Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor.

Abstract:

:Phagocytosis, H2O2 production, Mac-1 expression, and in vivo elimination of Listeria monocytogenes were enhanced in granulocyte colony-stimulating factor (G-CSF)-treated mice. Transfer of polymorphonuclear leukocytes prolonged survival of mice infected with a lethal dose of L. monocytogenes. G-CSF augments the functions of polymorphonuclear leukocytes and thus plays a role in protection.

journal_name

Infect Immun

journal_title

Infection and immunity

authors

Shinomiya N,Tsuru S,Katsura Y,Kayashima S,Nomoto K

doi

10.1128/IAI.59.12.4740-4743.1991

subject

Has Abstract

pub_date

1991-12-01 00:00:00

pages

4740-3

issue

12

eissn

0019-9567

issn

1098-5522

journal_volume

59

pub_type

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