Fap2 of Fusobacterium nucleatum is a galactose-inhibitable adhesin involved in coaggregation, cell adhesion, and preterm birth.

abstract：:Several studies have demonstrated roles for eosinophils during innate and adaptive immune responses to helminth infections. However, evidence that eosinophils are capable of initiating an immune response to parasite antigens is lacking. The goal of the present in vitro study was to investigate the potential of eosinop...

journal_title：Infection and immunity

authors： Padigel UM,Lee JJ,Nolan TJ,Schad GA,Abraham D

更新日期：2006-06-01 00:00:00

abstract：:Streptococcal pyrogenic exotoxin B (SpeB), a conserved cysteine protease expressed by virtually all Streptococcus pyogenes strains, has recently been shown to be an important virulence factor (S. Lukomski, S. Sreevatsan, C. Amberg, W. Reichardt, M. Woischnik, A. Podbielski, and J. M. Musser, J. Clin. Invest. 99:2574-2...

journal_title：Infection and immunity

authors： Lukomski S,Burns EH Jr,Wyde PR,Podbielski A,Rurangirwa J,Moore-Poveda DK,Musser JM

更新日期：1998-02-01 00:00:00

abstract：:Brucella spp. are gram-negative intracellular pathogens that survive and multiply within phagocytic cells of their hosts. Smooth organisms present O polysaccharides (OPS) on their surface. These OPS help the bacteria avoid the bactericidal action of serum. The wboA gene, coding for the enzyme glycosyltransferase, is e...

journal_title：Infection and immunity

authors： Fernandez-Prada CM,Nikolich M,Vemulapalli R,Sriranganathan N,Boyle SM,Schurig GG,Hadfield TL,Hoover DL

更新日期：2001-07-01 00:00:00

abstract：:The role of gamma-delta T cells in host resistance to Chlamydia trachomatis was characterized by using a murine model of pneumonia caused by the mouse pneumonitis agent (MoPn), murine C. trachomatis. At days 3 and 7 after infection, gamma-delta T-cell-deficient knockout mice had significantly higher levels of MoPn in ...

journal_title：Infection and immunity

authors： Williams DM,Grubbs BG,Kelly K,Pack E,Rank RG

更新日期：1996-09-01 00:00:00

abstract：:Lipopolysaccharides (LPS), either in the free form or complexed to CD14, a LPS receptor, are elicitors of the immune system. Lactoferrin (Lf), a LPS-chelating glycoprotein, protects animals against septic shock. Since optimal protection requires administration of Lf prior to lethal doses of LPS, we hypothesized that i...

journal_title：Infection and immunity

authors： Baveye S,Elass E,Fernig DG,Blanquart C,Mazurier J,Legrand D

更新日期：2000-12-01 00:00:00

abstract：:Cryptosporidial infections were established in five young foals with severe combined immunodeficiency following oral administration of 10(8) Cryptosporidium parvum oocysts. All foals shed oocysts (average of 8 x 10(6) to 2 x 10(8)/g of feces) until death. Inflammation and C. parvum organisms were observed in the commo...

journal_title：Infection and immunity

authors： Bjorneby JM,Leach DR,Perryman LE

更新日期：1991-10-01 00:00:00

abstract：:Vibrio cholerae O1 bacteria harvested directly from ligated or nonligated intestines of rabbits with experimental cholera expressed at least 7 to 8 novel, in vivo-specific cell envelope (env) proteins that were not found on vibrios after in vitro culture in various ordinary liquid media. At the same time, several of t...

journal_title：Infection and immunity

authors： Jonson G,Svennerholm AM,Holmgren J

更新日期：1989-06-01 00:00:00

abstract：:Schistosoma mansoni eggs produced by adult worms in the mesenteric vasculature become trapped in the liver, where they induce granulomatous lesions and strong immune responses. Infected individuals suffer from intestinal schistosomiasis (INT) in 90% of cases, whereas the remaining 10% present with severe hepatosplenic...

journal_title：Infection and immunity

authors： Manivannan B,Rawson P,Jordan TW,Secor WE,La Flamme AC

更新日期：2010-02-01 00:00:00

abstract：:Porphyromonas gingivalis is a gram-negative anaerobic bacterium that is considered the key etiologic agent of chronic periodontitis. Arg- and Lys-gingipain cysteine proteinases produced by P. gingivalis are key virulence factors and are believed to be essential for significant tissue component degradation, leading to ...

journal_title：Infection and immunity

authors： Andrian E,Grenier D,Rouabhia M

更新日期：2004-08-01 00:00:00

abstract：:We determined the diphtheria toxin phenotype of specially selected isolates of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis (C. ovis). All produced proteins similar in size and immunological structure to diphtheria toxin. As with diphtheria toxin, they exhibited ADP-ribosylating activity, and their ...

journal_title：Infection and immunity

authors： Wong TP,Groman N

更新日期：1984-03-01 00:00:00

abstract：:The Leishmania pifanoi amastigote antigen P-8 has been previously shown to induce protective immunity in a murine model of cutaneous leishmaniasis (L. Soong, S. M. Duboise, P. Kima, and D. McMahon-Pratt, Infect. Immun. 63:3559-3566, 1995). As this antigen is of interest for further vaccine studies, the biochemical cha...

journal_title：Infection and immunity

authors： Colmenares M,Tiemeyer M,Kima P,McMahon-Pratt D

更新日期：2001-11-01 00:00:00

abstract：:Polymorphonuclear leukocytes (PMN) from patients with chronic granulomatous disease (CGD) fail to produce microbicidal concentrations of reactive oxygen species (ROS) due to mutations in NOX2. Patients with CGD suffer from severe, life-threatening infections and inflammatory complications. Granulibacter bethesdensis i...

journal_title：Infection and immunity

authors： Greenberg DE,Sturdevant DE,Marshall-Batty KR,Chu J,Pettinato AM,Virtaneva K,Lane J,Geller BL,Porcella SF,Gallin JI,Holland SM,Zarember KA

更新日期：2015-11-01 00:00:00

abstract：:Infection of CFW mice with Trichinella spiralis induced a state of relative unresponsiveness to passive cutaneous anaphylaxis (PCA) induced with hen egg albumin and its corresponding antibodies. The unresponsiveness was to PCA produced either with immunoglobulin G1 (IgG1) or IgE type of antibodies, but was more pronou...

journal_title：Infection and immunity

authors： Munoz JJ,Cole RL

更新日期：1977-01-01 00:00:00

abstract：:We found that thiols reduced the amount of cholera toxin produced by Vibrio cholerae 569B in vitro. A sulfhydryl group at least was necessary for the reduction of cholera toxin production by thiols. ...

journal_title：Infection and immunity

authors： Shimamura T,Watanabe S,Sasaki S

更新日期：1986-09-01 00:00:00

abstract：:Ehrlichia chaffeensis is an obligately intracellular gram-negative bacterium and is the etiologic agent of human monocytic ehrlichiosis (HME). Although E. chaffeensis induces the generation of several cytokines and chemokines by leukocytes, E. chaffeensis lacks lipopolysaccharide and peptidoglycan. Bioinfomatic analys...

journal_title：Infection and immunity

authors： Huang H,Lin M,Wang X,Kikuchi T,Mottaz H,Norbeck A,Rikihisa Y

更新日期：2008-08-01 00:00:00

abstract：:Black melanin-like pigments are produced by several neurotropic fungi, including Cryptococcus neoformans. Pigment production is associated with virulence. In media containing phenolic substrates such as L-dopa, C. neoformans cells become black as a result of pigment accumulation. Pigmented and nonpigmented C. neoforma...

journal_title：Infection and immunity

authors： Wang Y,Aisen P,Casadevall A

更新日期：1995-08-01 00:00:00

abstract：:Streptococcus iniae causes systemic infection characterized by meningitis and sepsis. Here, we report a larval zebrafish model of S. iniae infection. Injection of wild-type S. iniae into the otic vesicle induced a lethal infection by 24 h postinfection. In contrast, an S. iniae mutant deficient in polysaccharide capsu...

journal_title：Infection and immunity

authors： Harvie EA,Green JM,Neely MN,Huttenlocher A

更新日期：2013-01-01 00:00:00

abstract：:Antigenic competition between bovine gamma globulin (BGG) and endotoxin from a smooth strain (S-ET) and a rough (R-ET) heptoseless mutant strain of Salmonella minnesota was studied in mice. Both endotoxins acted as adjuvants for enhancing the antibody response to BGG. However, other work showed that the R-ET had minim...

journal_title：Infection and immunity

authors： Leong DL,Rudbach JA

更新日期：1971-02-01 00:00:00

abstract：:Mycobacterium marinum grows at an optimal temperature of 33 degrees C, far lower than that for M. tuberculosis. Consequently, M. marinum infection of mammals is restricted largely to the cooler surfaces of the body, such as the extremities, but it causes a systemic infection in a large number of poikilothermic animals...

journal_title：Infection and immunity

authors： Ramakrishnan L,Valdivia RH,McKerrow JH,Falkow S

更新日期：1997-02-01 00:00:00

abstract：:Ehrlichia chaffeensis, an obligatory intracellular bacterium of monocytes or macrophages, is the etiologic agent of human monocytic ehrlichiosis. Our previous study showed that gamma interferon (IFN-gamma) added prior to or at early stage of infection inhibited infection of human monocytes with E. chaffeensis; however...

journal_title：Infection and immunity

authors： Lee EH,Rikihisa Y

更新日期：1998-06-01 00:00:00

abstract：:An anti-glucosyltransferase serum was prepared against a pure enzyme preparation from Streptococcus sanguis OMZ 9, which synthesized both soluble and insoluble dextran. Sera, crude gamma globulins, and antibody fractions obtained after gel filtration on a Bio-Gel P200 column were used to study enzyme-antibody interact...

journal_title：Infection and immunity

authors： Klein JP,Schöller M,Frank RM

更新日期：1978-06-01 00:00:00

abstract：:Chlamydia trachomatis L2 is an obligate intracellular microorganism with a unique biphasic life cycle. The extracellular form, the elementary body (EB), is infectious but metabolically inactive. Attachment of EBs to host cells is medicated by a heparan sulfate-like glycosaminoglycan. Following attachment, the EB is in...

journal_title：Infection and immunity

authors： Birkelund S,Johnsen H,Christiansen G

更新日期：1994-11-01 00:00:00

abstract：:The adherence of Enterococcus faecalis strains to human T24 cells was examined by scanning electron microscopy. Five highly adhesive strains were identified from 30 strains isolated from the urine of patients with urinary tract infections. No efficiently adhesive strains were found among the 30 strains isolated from t...

journal_title：Infection and immunity

authors： Shiono A,Ike Y

更新日期：1999-04-01 00:00:00

abstract：:The selection of influenza B virus recombinants from plaques in bovine kidney cell monolayers is described. Two sets of recombinants were each derived from parents of high and low virulence for humans, respectively. Recombination frequency was apparently high, and reassortment of genes made it possible to obtain atten...

journal_title：Infection and immunity

authors： Beare AS,Sherwood JE,Callow KA,Craig JW

更新日期：1977-02-01 00:00:00

abstract：:White-footed mice (Peromyscus leucopus), the primary reservoir for Borrelia burgdorferi in the northern midwest and northeastern United States, were experimentally inoculated with an infectious strain or a noninfectious strain of the Lyme disease spirochete and examined for their specific antibody response with the en...

journal_title：Infection and immunity

authors： Schwan TG,Kime KK,Schrumpf ME,Coe JE,Simpson WJ

更新日期：1989-11-01 00:00:00

abstract：:The P8 proteoglycolipid complex (P8 PGLC) is a glyconjugate expressed by Leishmania mexicana complex parasites. We previously have shown that vaccination with P8 PGLC provides protection against cutaneous leishmaniasis in susceptible BALB/c mice. However, the biological importance of this complex remains unknown. Here...

journal_title：Infection and immunity

authors： Whitaker SM,Colmenares M,Pestana KG,McMahon-Pratt D

更新日期：2008-05-01 00:00:00

abstract：:The NikR protein is a nickel-dependent regulatory protein which is a member of the ribbon-helix-helix family of transcriptional regulators. The gastric pathogen Helicobacter pylori expresses a NikR ortholog, which was previously shown to mediate regulation of metal metabolism and urease expression, but the mechanism g...

journal_title：Infection and immunity

authors： Ernst FD,Kuipers EJ,Heijens A,Sarwari R,Stoof J,Penn CW,Kusters JG,van Vliet AH

更新日期：2005-11-01 00:00:00

abstract：:The cytopathic effect (CPE) of Escherichia coli producing cytotoxic necrotizing factor type 1 (CNF1) was investigated by using a human epithelial cell (HeLa) model of infection with CNF1-producing E. coli BM2-1. This strain was shown to bind loosely, but massively, to HeLa cells. A 4-h interaction between bacteria and...

journal_title：Infection and immunity

authors： De Rycke J,Mazars P,Nougayrede JP,Tasca C,Boury M,Herault F,Valette A,Oswald E

更新日期：1996-05-01 00:00:00

abstract：:H(2)O(2) levels accumulated by Mycoplasma pneumoniae can be influenced by carbon source, different horse sera, yeast extract, thallium acetate, or growth in a simplified, dialyzed medium. Thus, increased levels of H(2)O(2) were detected by growth in glycerol, by omission of thallium acetate, and by the use of dialyzed...

journal_title：Infection and immunity

authors： Low IE

更新日期：1971-01-01 00:00:00

abstract：:Borrelia burgdorferi resembles gram-negative bacteria in having both cellular and outer membranes. We previously showed that a lipopolysaccharide (LPS)-like material could be extracted from B. burgdorferi with phenol-chloroform-petroleum ether (PCP). The PCP extract of B. burgdorferi exhibited biological activity in s...

journal_title：Infection and immunity

authors： Katona LI,Beck G,Habicht GS

更新日期：1992-12-01 00:00:00