Enhancement of growth of Mycobacterium lepraemurium in macrophages by gamma interferon.

Abstract:

:Gamma interferon, an immune lymphokine that protects mouse macrophages against infection by several parasites, was ineffective against Mycobacterium lepraemurium. On the contrary, it significantly stimulated multiplication of M. lepraemurium in the macrophages. Simultaneous treatment of macrophages with gamma interferon and interleukin-4 or interleukin-2 or a combination of all three did not enhance the macrophage resistance to infection with M. lepraemurium, but instead stimulated growth of M. lepraemurium.

journal_name

Infect Immun

journal_title

Infection and immunity

authors

Mor N,Goren MB,Crowle AJ

doi

10.1128/IAI.57.8.2586-2587.1989

subject

Has Abstract

pub_date

1989-08-01 00:00:00

pages

2586-7

issue

8

eissn

0019-9567

issn

1098-5522

journal_volume

57

pub_type

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