Absence of a prominent Th2 cytokine response in human tuberculosis.

abstract：:In Pseudomonas aeruginosa, the second messenger cyclic-di-GMP and Gac/Rsm signaling pathways are associated with the transition from acute to chronic infection. Therefore, identification of the molecular mechanisms that govern lifestyle choice in bacteria is very important. Here, we identified a novel cyclic-di-GMP mo...

journal_title：Infection and immunity

authors： Jiao H,Li F,Wang T,Yam JKH,Yang L,Liang H

更新日期：2021-01-19 00:00:00

abstract：:Phorbol myristate acetate stimulated oxidative metabolism in alveolar macrophages and blood neutrophils. This compound also stimulated lysozyme release from neutrophils but not from alveolar macrophages. These findings suggest that the regulation of lysozyme release from alveolar macrophages is different than for poly...

journal_title：Infection and immunity

authors： Biggar WD

更新日期：1978-08-01 00:00:00

abstract：:Protection against infection with virulent blood (trypomastigote) forms of Trypanosoma cruzi was accomplished in mice by immunization with culture (mainly epimastigote) forms killed by treatment with sodium perchlorate. Sodium chloride, used instead of sodium perchlorate, with all other conditions kept the same, faile...

journal_title：Infection and immunity

authors： Kierszenbaum F,Budzko DB

更新日期：1975-09-01 00:00:00

abstract：:In order to develop a new system for the analysis of capsular biosynthetic pathways we have explored the possibility of expressing type 3 capsular polysaccharide (CPS) from the pathogen Streptococcus pneumoniae in Lactococcus lactis, an unencapsulated lactic acid bacterium being developed as a vaccine delivery vehicle...

journal_title：Infection and immunity

authors： Gilbert C,Robinson K,Le Page RW,Wells JM

更新日期：2000-06-01 00:00:00

abstract：:Streptococcus pyogenes is one of the most frequent human pathogens. Recent studies have identified dendritic cells (DCs) as important contributors to host defense against S. pyogenes. The objective of this study was to identify the receptors involved in immune recognition of S. pyogenes by DCs. To determine whether To...

journal_title：Infection and immunity

authors： Loof TG,Goldmann O,Medina E

更新日期：2008-06-01 00:00:00

abstract：:3-O-methylmannose isolated from Coccidioides immitis was characterized by gas chromatographic comparison of derivatives with those of synthetic 3-O-methylmannose. Gas chromatographic behavior of three derivatives of the natural and synthetic sugars was identical. ...

journal_title：Infection and immunity

authors： Porter JF,Scheer ER,Wheat RW

更新日期：1971-11-01 00:00:00

abstract：:The effects of an ornithine-containing lipid [alpha-N-(3-acyloxyacyl)-ornithine (Orn-L)] or a serine-containing lipid [alpha-N-(3-acyloxyacyl)-serine (Ser-L)] from Flavobacterium meningosepticum on lethal endotoxemia in mice were examined. When 500 micrograms of Orn-L was intravenously administered 1 h before intraven...

journal_title：Infection and immunity

authors： Kawai Y,Kaneda K,Morisawa Y,Akagawa K

更新日期：1991-08-01 00:00:00

abstract：:We have constructed an improved recombination-based in vivo expression technology (RIVET) and used it as a screening method to identify Vibrio cholerae genes that are transcriptionally induced during infection of infant mice. The improvements include the introduction of modified substrate cassettes for resolvase that ...

journal_title：Infection and immunity

authors： Osorio CG,Crawford JA,Michalski J,Martinez-Wilson H,Kaper JB,Camilli A

更新日期：2005-02-01 00:00:00

abstract：:T cells are important in systemic anticryptococcal defenses, but a role in controlling an initial pulmonary infection has not been demonstrated. A murine model with intratracheal inoculation was developed to study the acquisition and expression of pulmonary T cell-mediated immunity against Cryptococcus neoformans. Inf...

journal_title：Infection and immunity

authors： Huffnagle GB,Yates JL,Lipscomb MF

更新日期：1991-04-01 00:00:00

abstract：:The Toll-like receptor 2 (TLR2)/TLR1 receptor complex responds to amyloid fibrils, a common component of biofilm material produced by members of the phyla Firmicutes, Bacteroidetes, and Proteobacteria. To determine whether this TLR2/TLR1 ligand stimulates inflammatory responses when bacteria enter intestinal tissue, w...

journal_title：Infection and immunity

authors： Nishimori JH,Newman TN,Oppong GO,Rapsinski GJ,Yen JH,Biesecker SG,Wilson RP,Butler BP,Winter MG,Tsolis RM,Ganea D,Tükel Ç

更新日期：2012-12-01 00:00:00

abstract：:Toxoplasma gondii and Neospora caninum (both Apicomplexa) are closely related cyst-forming coccidian parasites that differ significantly in their host ranges and ability to cause disease. Unlike eutherian mammals, Australian marsupials (metatherian mammals) have long been thought to be highly susceptible to toxoplasmo...

journal_title：Infection and immunity

authors： Donahoe SL,Phalen DN,McAllan BM,O'Meally D,McAllister MM,Ellis J,Šlapeta J

更新日期：2017-05-23 00:00:00

abstract：:Type II heat-labile enterotoxin (LT-II) from Escherichia coli 41 was purified and compared with prototype LT-II encoded by genes from E. coli SA53. Both toxins were oligomeric proteins consisting of polypeptides A (Mr, 28,000) and B (Mr, 11,800). The A polypeptides were cleaved by trypsin into fragments A1 (Mr, 21,000...

journal_title：Infection and immunity

authors： Guth BE,Twiddy EM,Trabulsi LR,Holmes RK

更新日期：1986-11-01 00:00:00

abstract：:A family of high-molecular-weight (HMW) surface-exposed proteins important in the attachment of nontypeable Haemophilus influenzae (NTHi) to human epithelial cells was previously identified (J. W. St. Geme III, S. Falkow, and S. J. Barenkamp, Proc. Natl. Acad. Sci. USA 90:2875-2879, 1993). In the present investigation...

journal_title：Infection and immunity

authors： Bakaletz LO,Barenkamp SJ

更新日期：1994-10-01 00:00:00

abstract：:Agglutinogen 1 of Bordetella pertussis strain 353/Z (serotype 1) was separated from protective antigen and histamine-sensitizing factor by starch-block electrophoresis. Most of the agglutinogen 1 migrated towards the cathode in starch-block electrophoresis, although some remained near the origin. Fractions containing ...

journal_title：Infection and immunity

authors： Ross RF,Munoz J

更新日期：1971-02-01 00:00:00

abstract：:Guinea pigs were treated with anti-CD18 antibody (M8), and subsequently middle ears (ME) were infected with nontypeable Haemophilus influenzae. Forty-eight hours after infection, the ME washes of these animals had significantly lower polymorphonuclear leukocyte numbers but higher bacterial counts compared with washes ...

journal_title：Infection and immunity

authors： Patel J,Chonmaitree T,Schmalstieg F

更新日期：1993-03-01 00:00:00

abstract：:Initiation of a gonococcal infection involves attachment of Neisseria gonorrhoeae to the plasma membrane of an epithelial cell in the mucosal epithelium and its internalization, transepithelial trafficking, and exocytosis from the basal membrane. Piliation and expression of certain Opa proteins and the immunoglobulin ...

journal_title：Infection and immunity

authors： Hopper S,Wilbur JS,Vasquez BL,Larson J,Clary S,Mehr IJ,Seifert HS,So M

更新日期：2000-02-01 00:00:00

abstract：:Aeromonas salmonicida causes furunculosis in salmonids and is a threat to Atlantic salmon aquaculture. The epithelial surfaces that the pathogen colonizes are covered by a mucus layer predominantly comprised of secreted mucins. By using mass spectrometry to identify mucin glycan structures with and without enzymatic r...

journal_title：Infection and immunity

authors： Padra JT,Sundh H,Sundell K,Venkatakrishnan V,Jin C,Samuelsson T,Karlsson NG,Lindén SK

更新日期：2017-07-19 00:00:00

abstract：:Vaccine candidates against Shigella dysenteriae type 1, which is associated with the most severe cases of bacillary dysentery, were constructed. The rfp and rfb gene clusters, which code for S. dysenteriae 1 O antigen biosynthesis, were randomly integrated into either the chromosome or the virulence plasmid of the rou...

journal_title：Infection and immunity

authors： Klee SR,Tzschaschel BD,Fält I,Kärnell A,Lindberg AA,Timmis KN,Guzmán CA

更新日期：1997-06-01 00:00:00

abstract：:Actinomyces naeslundii and Streptococcus gordonii, oral bacteria that possess Gal/GalNAc- and sialic acid-reactive lectins, respectively, were adherent to immobilized secretory immunoglobulin A (IgA) and two IgA1 myeloma proteins but not to two IgA2 myeloma proteins. Apparently, O-linked oligosaccharides at the hinge ...

journal_title：Infection and immunity

authors： Ruhl S,Sandberg AL,Cole MF,Cisar JO

更新日期：1996-12-01 00:00:00

abstract：:Tuberculosis remains the leading cause of death among infectious diseases, accounting for more than two million deaths annually. The incidence of the disease is increasing globally, partially because of the resurgence of drug-resistant strains of Mycobacterium tuberculosis. Calixarenes are macrocyclic oligomers, some ...

journal_title：Infection and immunity

authors： Colston MJ,Hailes HC,Stavropoulos E,Hervé AC,Hervé G,Goodworth KJ,Hill AM,Jenner P,Hart PD,Tascon RE

更新日期：2004-11-01 00:00:00

abstract：:Attachment and ingestion of Mycobacterium avium subsp. paratuberculosis by two epithelial cell lines were enhanced by soluble fibronectin (FN). Peptide blocking of the FN attachment protein (FAP-P) inhibited the internalization of M. avium subsp. paratuberculosis. Disruption of FAP-P expression significantly reduced a...

journal_title：Infection and immunity

authors： Secott TE,Lin TL,Wu CC

更新日期：2002-05-01 00:00:00

abstract：:Two extremely oxygen-sensitive strains of Clostridium sp., designated Clostridium E and P, were obtained from digestive microflora of conventional mice and found to constitute a barrier against Shigella flexneri SF-2 when associated in vivo with Escherichia coli K-12. These and other simplified fractions of the conven...

journal_title：Infection and immunity

authors： Ducluzeau R,Ladire M,Callut C,Raibaud P,Abrams GD

更新日期：1977-08-01 00:00:00

abstract：:Hemin induced germination of Candida albicans blastoconidia when cells grown up to the early exponential phase were shifted from 28 to 37 degrees C (70 to 75% of cells exhibited germ tubes). N-Acetyl-D-glucosamine (GlcNAc), another inducer of myceliation in this fungus, caused a similar effect. The combination of hemi...

journal_title：Infection and immunity

authors： Casanova M,Cervera AM,Gozalbo D,Martínez JP

更新日期：1997-10-01 00:00:00

abstract：:In this communication, we examine the specificity of anti-herpes simplex virus (HSV) cytotoxic T lymphocytes (CTL). Serological studies of the two related HSV serotypes (HSV-1 and HSV-2) have revealed both type-specific and cross-reactive antigenic determinants in the viral envelope and on the surface of infected cell...

journal_title：Infection and immunity

authors： Eberle R,Russell RG,Rouse BT

更新日期：1981-12-01 00:00:00

abstract：:Urinary tract infections (UTIs) are among the most common infectious diseases of humans, with Escherichia coli responsible for >80% of all cases. One extreme of UTI is asymptomatic bacteriuria (ABU), which occurs as an asymptomatic carrier state that resembles commensalism. To understand the evolution and molecular me...

journal_title：Infection and immunity

authors： Beatson SA,Ben Zakour NL,Totsika M,Forde BM,Watts RE,Mabbett AN,Szubert JM,Sarkar S,Phan MD,Peters KM,Petty NK,Alikhan NF,Sullivan MJ,Gawthorne JA,Stanton-Cook M,Nhu NT,Chong TM,Yin WF,Chan KG,Hancock V,Ussery DW

更新日期：2015-05-01 00:00:00

abstract：:Minor salivary glands of the oral mucosa in healthy monkeys (Macaca fascicularis and Macaca mulatta) contain organized structural units suitable for recognizing and processing antigens. A previous study of M. fascicularis monkeys provided experimental evidence of retrograde access of oral antigens deep into the minor ...

journal_title：Infection and immunity

authors： Nair PN,Schroeder HE

更新日期：1983-07-01 00:00:00

abstract：:Bacterial superantigens (SAgs) have been implicated in inflammatory disease, and SAg-treated mice have increased jejunal T cells. Here we show that T84 cells (a human epithelial cell line) display increased MCP-1 and RANTES mRNA expression and protein production in response to conditioned medium from Staphylococcus au...

journal_title：Infection and immunity

authors： Jedrzkiewicz S,Kataeva G,Hogaboam CM,Kunkel SL,Strieter RM,McKay DM

更新日期：1999-11-01 00:00:00

abstract：:Streptococcus equi and Streptococcus zooepidemicus are major etiological agents of upper and lower airway disease in horses. Despite the considerable animal suffering and economic burden associated with these diseases, the factors that contribute to the virulence of these equine pathogens have not been extensively inv...

journal_title：Infection and immunity

authors： Harrington DJ,Greated JS,Chanter N,Sutcliffe IC

更新日期：2000-10-01 00:00:00

abstract：:Previously we demonstrated that recombinant murine interleukin-12 (rmIL-12) administration can promote a primary Th1 response while suppressing the Th2 response in mice primed with 2,4, 6-trinitrophenyl-keyhole limpet hemocyanin (TNP-KLH). The present studies examined the capacity of rmIL-12 to drive a Th1 response to...

journal_title：Infection and immunity

authors： Schopf LR,Bliss JL,Lavigne LM,Chung CL,Wolf SF,Sypek JP

更新日期：1999-05-01 00:00:00

abstract：:A novel immunobiologically active fraction was prepared from a phenol-water extract of Prevotella intermedia ATCC 25611 by Sephadex G-100 column chromatography. The fraction consisted mainly of carbohydrate and protein and was devoid of fatty acid. The fraction showed high-molecular-weight bands (10,000 to 12,000) on ...

journal_title：Infection and immunity

authors： Iki K,Kawahara K,Sawamura S,Arakaki R,Sakuta T,Sugiyama A,Tamura H,Sueda T,Hamada S,Takada H

更新日期：1997-11-01 00:00:00