Polymorphism of the 5'-upstream region of the human SNAP-25 gene: an association analysis with schizophrenia.

abstract：:Carnitine is essential for mitochondrial energy production. Disturbance in mitochondrial function may contribute to or cause the fatigue seen in chronic fatigue syndrome (CFS) patients. One previous investigation has reported decreased acylcarnitine levels in 38 CFS patients. We investigated 35 CFS patients (27 female...

journal_title：Neuropsychobiology

authors： Plioplys AV,Plioplys S

更新日期：1995-01-01 00:00:00

abstract：:Genetic polymorphism of the serotonin 5-HT(2A) receptor seems to be associated with therapeutic response to selective serotonin reuptake inhibitors (SSRIs). The present study investigated whether a novel -1438G/A polymorphism in the promoter region of the 5-HT(2A )receptor gene is associated with therapeutic response ...

journal_title：Neuropsychobiology

authors： Sato K,Yoshida K,Takahashi H,Ito K,Kamata M,Higuchi H,Shimizu T,Itoh K,Inoue K,Tezuka T,Suzuki T,Ohkubo T,Sugawara K,Otani K

更新日期：2002-01-01 00:00:00

abstract：:An association between negative symptoms and frontal cortex abnormalities has been suggested in schizophrenic patients. We tested whether this association can be found when patients' task performance is good and while controlling for possible cortical atrophy. We investigated regional cerebral blood flow with the xeno...

journal_title：Neuropsychobiology

authors： Zemishlany Z,Alexander GE,Prohovnik I,Goldman RG,Mukherjee S,Sackeim H

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:In general, humans tend to discount the value of delayed reward. An increase in the rate of discounting leads to an inability to select a delayed reward over a smaller immediate reward (reward-delay impulsivity). Although deficits in the serotonergic system are implicated in this reward-delay impulsivit...

journal_title：Neuropsychobiology

authors： Demoto Y,Okada G,Okamoto Y,Kunisato Y,Aoyama S,Onoda K,Munakata A,Nomura M,Tanaka SC,Schweighofer N,Doya K,Yamawaki S

更新日期：2012-01-01 00:00:00

abstract：:Alcohol-dependent patients face a substantial risk of relapse after detoxification. Though psychosocial stress and coping strategies are regarded as major contributing factors in returning to drinking, the direct effects of coping styles on relapse are not clear. In this treatment outcome study, a mixed gender sample ...

journal_title：Neuropsychobiology

authors： Walter M,Gerhard U,Duersteler-MacFarland KM,Weijers HG,Boening J,Wiesbeck GA

更新日期：2006-01-01 00:00:00

abstract：:The purpose of this study was to investigate the relationship between postoperative confusion and the plasma norepinephrine (NE), adrenocorticotropin (ACTH) or cortisol response to surgery in schizophrenic patients. We studied 50 schizophrenic patients and 35 control patients who underwent orthopedic surgery and perio...

journal_title：Neuropsychobiology

authors： Kudoh A,Takahira Y,Katagai H,Takazawa T

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:We have investigated the efficacy of high-frequency left (HFL) versus low-frequency right (LFR) repetitive transcranial magnetic stimulation (rTMS) in depression, focusing on specific symptoms as possible predictors of outcome for these two different types of stimulation. METHOD:Seventy-four outpatients wit...

journal_title：Neuropsychobiology

authors： Rossini D,Lucca A,Magri L,Malaguti A,Smeraldi E,Colombo C,Zanardi R

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:There is some evidence that repetitive transcranial magnetic stimulation (rTMS) is an effective method of treating patients suffering from obsessive-compulsive disorder (OCD). Here, we tested the hypothesis that rTMS has a positive impact both on symptom severity and cognitive performance in such patients. Sp...

journal_title：Neuropsychobiology

authors： Jahangard L,Haghighi M,Shyayganfard M,Ahmadpanah M,Sadeghi Bahmani D,Bajoghli H,Holsboer-Trachsler E,Brand S

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIM:Repetitive transcranial magnetic stimulation (rTMS) is supposed to be not as effective in severe depression as it is in medium depression. We evaluated the treatment response to an ultra-high-frequency (UHF; 30 Hz) approach, which was used to maximize the rTMS efficacy in severely ill patients. METH...

journal_title：Neuropsychobiology

authors： Ullrich H,Kranaster L,Sigges E,Andrich J,Sartorius A

更新日期：2012-01-01 00:00:00

abstract：:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical import...

journal_title：Neuropsychobiology

authors： Refsum HE,Astrup C

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Patients with bipolar disorder are at a high risk for becoming obese. Adipokines are associated with depression and obesity via the inflammatory process. However, few studies have investigated the associations between depression and leptin, adiponectin and resistin levels in patients with bipolar disorder. W...

journal_title：Neuropsychobiology

authors： Lee HJ,Kim SH,Kim EY,Lee NY,Yu HY,Kim YS,Ahn YM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The characterization of an individual's hypothalamic-pituitary-adrenal axis stress response is a main research topic in neuropsychobiology since alterations have been causally linked to several disease states. Over the last years, several studies focused on the identification of sources of inter- and intrain...

journal_title：Neuropsychobiology

authors： Kudielka BM,Fischer JE,Metzenthin P,Helfricht S,Preckel D,von Känel R

更新日期：2007-01-01 00:00:00

abstract：:Piracetam, when applied microiontophoretically and/or by hydropneumatic pump on the somatosensory cortex and hippocampus of the rat, affected neuronal activity by depressing or facilitating the spontaneous firing rate, depending on the area studied. Its effect were either additive or counteracting the actions of gluta...

journal_title：Neuropsychobiology

authors： Maillis A,Karayanidis F,Koutsoukos E,Angelopoulos E,Stefanis C

更新日期：1988-01-01 00:00:00

abstract：:10 long-term schizophrenic patients with tardive dyskinesia were studied over 14 weeks and maintained on their usual neuroleptic medications while anticholinergic antiparkinson drugs were employed and then discontinued, and the cycle then repeated. Discontinuation of anticholinergic medications resulted in improvement...

journal_title：Neuropsychobiology

authors： Burnett GB,Prange AJ Jr,Wilson IC,Jolliff LA,Creese IC,Synder SH

更新日期：1980-01-01 00:00:00

abstract：:Substance P (SP) is a neuropeptide which is abundant in the periphery and the central nervous system, where it is colocalized with other neurotransmitters such as serotonin or dopamine. SP has been proposed to play a role in the regulation of pain including migraine and fibromyalgia, asthma, inflammatory bowel disease...

journal_title：Neuropsychobiology

authors： Lieb K,Treffurth Y,Berger M,Fiebich BL

更新日期：2002-01-01 00:00:00

abstract：:The effects of the dopaminergic agonists (L-dopa, pergolide) and antagonists (haloperidol, clozapin) and a cholinergic agonist (tacrine) and antagonist (mecamylamine) on the voluntary intake of nicotine were investigated with the 2-bottle paradigm with the test drugs being dissolved directly in the drinking fluid of t...

journal_title：Neuropsychobiology

authors： Kameda G,Dadmarz M,Vogel WH

更新日期：2000-01-01 00:00:00

abstract：:The analysis of the results obtained in different tests--sleep studies, cortical and hippocampal EEG activity, PGO-R spikes--in rats or in cats allows the characterization of different classes of drugs and to establish the relative efficacy of psychoactive drugs in these models. Moreover, the sequential spectral analy...

journal_title：Neuropsychobiology

authors： Depoortere H,Decobert M,Honoré L

更新日期：1983-01-01 00:00:00

abstract：:Two preliminary studies have indicated a variation in season of birth in severely language-disordered children. In the current study, the season of birth in 472 Danish children with language disorder born between 1958 and 1976 was compared with the season of birth of all Danish live-born children in the same period. F...

journal_title：Neuropsychobiology

authors： Hauschild KM,Mouridsen SE,Nielsen S

更新日期：2005-01-01 00:00:00

abstract：:This study aimed to investigate the binding affinity of [3H]GABA and [3H]beta-alanine to GABA transporters GAT-1 and GAT-3 in the human dorsolateral prefrontal cortex (Brodmanns' area 9) in schizophrenia. Using post mortem tissue from individuals diagnosed with schizophrenia (n=6) and control subjects (n=6), the densi...

journal_title：Neuropsychobiology

authors： Schleimer SB,Hinton T,Dixon G,Johnston GA

更新日期：2004-01-01 00:00:00

abstract：:Dysfunctional mechanisms in the serotonergic system have been implicated in suicidal behavior among patients with schizophrenia. However, previous association analyses of major serotonin genes have provided inconsistent findings regarding their role in suicidal behavior. The goal of the current study was to identify s...

journal_title：Neuropsychobiology

authors： Bani-Fatemi A,Howe AS,Matmari M,Koga A,Zai C,Strauss J,De Luca V

更新日期：2016-01-01 00:00:00

abstract：:There is evidence that serotonin and norepinephrine are in some way involved in the pathophysiology of anxiety disorders. Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 46 patients with generalized anxiety di...

journal_title：Neuropsychobiology

authors： Garvey MJ,Noyes R Jr,Woodman C,Laukes C

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Apolipoprotein E (APOE) is polymorphic, and may be involved in the pathogenesis and clinical expression of schizophrenia. This study aimed to investigate the frequency of specific APOE genotypes and alleles in a schizophrenic Arab population and evaluate the association of specific APOE types with clinical p...

journal_title：Neuropsychobiology

authors： Akanji AO,Ohaeri JU,Al-Shammri SN,Fatania HR

更新日期：2009-01-01 00:00:00

abstract：:We examined the chronic effects of desipramine and mianserin on increases of intracellular Ca2+ concentration ([Ca2+]i) induced by noradrenaline (NA), acetylcholine (ACh), or high K+ in cultured neurons of rat frontal cortex, using fluoromicroscopic analysis with Ca(2+)-sensitive dye fura-2. NA- and ACh-induced [Ca2+]...

journal_title：Neuropsychobiology

authors： Shimizu M,Nishida A,Fukuda H,Saito H,Yamawaki S

更新日期：1996-01-01 00:00:00

abstract：:The systematic recording of spontaneous electrodermal activity (EDA) on 23 normal subjects during 5 15-min sessions and the self-rating of anxious and/or depressive moods (Q-sort forced choice) shows a positive linear relationship between spontaneous EDA and anxious mood despite a low covariation between those two var...

journal_title：Neuropsychobiology

authors： de Bonis M,Baqué EF

更新日期：1978-01-01 00:00:00

abstract：:Abnormal anterior pituitary responsiveness to acute administration of thyrotropin-releasing hormone was investigated in 8 patients, 6 women and 2 men, with primary affective disorders in a depressive phase and in 2 women with schizoaffective disorders. Thyrotropin-releasing hormone, 500 micrograms i.v., induced a rise...

journal_title：Neuropsychobiology

authors： Brambilla F,Scarone S,Massironi R,Nobile P,Pugnetti L

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:Due to its pharmacological properties, opipramol may be useful in the context of evening premedication in anaesthesiology. This trial examines whether quality of sleep the night prior to surgery can be improved by opipramol and whether this effect is dose dependent. A second objective of this study is to exam...

journal_title：Neuropsychobiology

authors： Hueppe M,Hartge D,Stoll KD,Ros A,Schmucker P,Gerlach K

更新日期：2011-01-01 00:00:00

abstract：:Growth hormone (GH) possesses multiple metabolic effects, in particular with regard to glucose and lipid homeostasis. Studies on the effects of GH on body weight and food and water intake are scarce and have yielded controversial results. We investigated the effects of different modes of GH administration on the param...

journal_title：Neuropsychobiology

authors： Schulz C,Wieczorek I,Reschke K,Lehnert H

更新日期：2002-01-01 00:00:00

abstract：:Fifteen general practitioners treated 21 newly diagnosed insomniac patients with benzodiazepines. In 15 cases, a short-acting benzodiazepine was prescribed without regard to the type, severity, duration and probable cause of insomnia. Sleep-wake ambulatory recordings were made at the respective homes of the patients b...

journal_title：Neuropsychobiology

authors： Wauquier A,Declerck A

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Eugen Bleuler, in his book Dementia praecox oder Gruppe der Schizophrenien, discussed issues of social psychiatry, and he considered complex interventions pivotal in the care for people with schizophrenia. Bleuler emphasised the potential of therapeutic communities in providing care, the drawbacks of extende...

journal_title：Neuropsychobiology

authors： Becker T,Kösters M

更新日期：2012-01-01 00:00:00

abstract：:Dopamine depletion induced by administration of Ro4-1284 produces a condition of rapid and repeated eye blinking in rats. This condition mimics the human disorder, blepharospasm, which often accompanies parkinsonism and other dopamine deficiency disorders. When given a 3-week course of a compound (SR-3) developed from...

journal_title：Neuropsychobiology

authors： Mostofsky DI,Yehuda S,Rabinovitz S,Carasso R

更新日期：2000-01-01 00:00:00