Repetitive Transcranial Magnetic Stimulation Improved Symptoms of Obsessive-Compulsive Disorder, but Also Cognitive Performance: Results from a Randomized Clinical Trial with a Cross-Over Design and Sham Condition.

abstract：BACKGROUND:In alcohol and other substance dependencies, patients often suffer relapse despite better knowledge and their intention to remain abstinent. A variety of neurotransmitter systems and their respective alterations due to the chronic drug intake are involved in mechanisms that facilitate relapse. It has been po...

journal_title：Neuropsychobiology

authors： Garbusow M,Sebold M,Beck A,Heinz A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The 5-hydroxytryptamine (5-HT) neurotransmitter system and lateral habenula (LHb) are involved in the regulation of depression, while the mechanisms remain to be clarified. OBJECTIVES:The effects and possible mecha-nism underlying activation or blockade of 5-HT4 receptors (5-HT4Rs) in the LHb in depression ...

journal_title：Neuropsychobiology

authors： Guo Y,Zhang L,Zhang J,Lv SX,Du CX,Wang T,Wang HS,Xie W,Liu J

更新日期：2020-07-14 00:00:00

abstract：:Neural-network pattern classifiers were used to study the effects of long half-life flurazepam (30 mg) and quazepam (15 mg), and short half-life triazolam (0.5 mg) on non-REM sleep. We measured the magnitude of effect, time course, and EEG spectral signature of the three benzodiazepines as a function of third-of-night...

journal_title：Neuropsychobiology

authors： Gevins AS,Stone RK,Ragsdale SD

更新日期：1988-01-01 00:00:00

abstract：:Morningness-eveningness preference by the self-rated Morningness-Eveningness Questionnaire (MEQ) has earlier been shown to be associated with the subjects' season of birth. Here, we obtain this result for a new sample of 2,125 university students and for the sample obtained by pooling the data with the earlier study, ...

journal_title：Neuropsychobiology

authors： Natale V,Adan A,Chotai J

更新日期：2002-01-01 00:00:00

abstract：:We agree with the conclusions of a recent article in this journal [James, Neuropsychobiology 1994;30:124-125] that studies on the psychoactive effects of caffeine need to take into account the possibility that the results obtained might represent merely the reversal of deleterious effects of caffeine deprivation rathe...

journal_title：Neuropsychobiology

authors： Rogers PJ,Richardson NJ,Dernoncourt C

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Psychosis spectrum disorders, especially schizophrenia, have been linked to disturbed dopaminergic activity in the brain. Plasma homovanillic acid (pHVA) levels partly represent dopaminergic metabolism in the central nervous system. In the present study associations between (changes in) pHVA levels, symptom ...

journal_title：Neuropsychobiology

authors： van de Kerkhof NW,Fekkes D,van der Heijden FM,Egger JI,Verhoeven WM

更新日期：2015-01-01 00:00:00

abstract：:There is evidence that serotonin and norepinephrine are in some way involved in the pathophysiology of anxiety disorders. Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 46 patients with generalized anxiety di...

journal_title：Neuropsychobiology

authors： Garvey MJ,Noyes R Jr,Woodman C,Laukes C

更新日期：1995-01-01 00:00:00

abstract：:The analysis of the results obtained in different tests--sleep studies, cortical and hippocampal EEG activity, PGO-R spikes--in rats or in cats allows the characterization of different classes of drugs and to establish the relative efficacy of psychoactive drugs in these models. Moreover, the sequential spectral analy...

journal_title：Neuropsychobiology

authors： Depoortere H,Decobert M,Honoré L

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND/AIMS:Valproic acid or valproate (VA) is an anticonvulsant and mood-stabilizing drug primarily used in the treatment of epilepsy and bipolar disorder. Ziprasidone (ZPN) is an atypical antipsychotic drug used mainly for the treatment of schizophrenia. METHODS:This study is a part of our investigation on the c...

journal_title：Neuropsychobiology

authors： Karapidaki I,Ekonomopoulou MT,Akritopoulou K,Anestakis D,Iakovidou-Kritsi Z

更新日期：2011-01-01 00:00:00

abstract：:The serotonergic system has been implicated in the production of the N1 and P2 components of auditory evoked potentials (AEPs). Moreover, studies have indicated the influence of heritability in the genesis of these AEP components. The serotonin transporter is the major site of serotonin reuptake into the presynaptic n...

journal_title：Neuropsychobiology

authors： Chen TJ,Yu YW,Chen MC,Tsai SJ,Hong CJ

更新日期：2002-01-01 00:00:00

abstract：:The formerly designed method for quantitative evaluation of drug effects in rats is employed for the classification of three different neuroleptic drugs, namely sulpiride, clozapine and haloperidol. Analysis of the power density spectra as obtained from the recorded activity in the cortex, striatum and reticular core ...

journal_title：Neuropsychobiology

authors： Dimpfel W,Decker H

更新日期：1985-01-01 00:00:00

abstract：:Alcohol-dependent patients face a substantial risk of relapse after detoxification. Though psychosocial stress and coping strategies are regarded as major contributing factors in returning to drinking, the direct effects of coping styles on relapse are not clear. In this treatment outcome study, a mixed gender sample ...

journal_title：Neuropsychobiology

authors： Walter M,Gerhard U,Duersteler-MacFarland KM,Weijers HG,Boening J,Wiesbeck GA

更新日期：2006-01-01 00:00:00

abstract：:Dopamine depletion induced by administration of Ro4-1284 produces a condition of rapid and repeated eye blinking in rats. This condition mimics the human disorder, blepharospasm, which often accompanies parkinsonism and other dopamine deficiency disorders. When given a 3-week course of a compound (SR-3) developed from...

journal_title：Neuropsychobiology

authors： Mostofsky DI,Yehuda S,Rabinovitz S,Carasso R

更新日期：2000-01-01 00:00:00

abstract：:Twelve healthy male volunteers received pyritinol 600 or 1,200 mg or placebo for 3 days according to a randomised, double-blind crossover design. On the 1st and 3rd days of each of the three treatment periods subjects completed a battery of psychological tests including Critical Flicker Fusion (CFFT), Choice Reaction ...

journal_title：Neuropsychobiology

authors： Hindmarch I,Coleston DM,Kerr JS

更新日期：1990-01-01 00:00:00

abstract：:The relationship between clinical effect of imipramine (IP) in 39 depressed patients and biochemical distinction, serum drug levels, and diagnostic classification was investigated retrospectively. Based on pretreatment plasma ratios of tryptophan and tyrosine to competing amino acids, which reflect the availability of...

journal_title：Neuropsychobiology

authors： Møller SE,Reisby N,Elley J,Krautwald O,Ortmann J,Larsen OB

更新日期：1985-01-01 00:00:00

abstract：:Monoamine oxidase A (MAOA) is a mitochondrial enzyme involved in the degradation of dopamine, serotonin and norepinephrine and these neurotransmitters are hypothesized to be involved in the cognitive function of humans. This study of a cohort of 191 healthy young Chinese females attempts to utilize the intelligence qu...

journal_title：Neuropsychobiology

authors： Yu YW,Tsai SJ,Hong CJ,Chen MC,Yang CW,Chen TJ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Women have twice the rate of depression and anxiety disorders as men. Some studies suggest that this could be caused by women's greater sensitivity to negative emotions. Few brain imaging studies have compared the brain activity of men to women during a presentation of emotional stimuli. Our objective was to...

journal_title：Neuropsychobiology

authors： Thomas M,Gaudeau-Bosma C,Bouaziz N,Schenin-King Andrianisaina P,Benadhira R,Januel D,Moulier V

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Limbic circuitry, especially the anterior cingulate gyrus, has been implicated in the pathophysiology and cognitive changes of schizophrenia. Previous diffusion tensor imaging studies have demonstrated that the integrity of the anterior cingulum (AC) is abnormal in schizophrenia. However, the relationship be...

journal_title：Neuropsychobiology

authors： Hayakawa YK,Kirino E,Shimoji K,Kamagata K,Hori M,Ito K,Kunimatsu A,Abe O,Ohtomo K,Aoki S

更新日期：2013-01-01 00:00:00

abstract：:7 women and 3 men with anorexia nervosa were tested with thyrotropin-releasing hormone (TRH) and luteinizing hormone-follicle stimulating hormone-releasing hormone (LH-RH) and the growth hormone (GH), prolactin (PRL), gonadotropin (FSH-LH) and thyrotropin (TSH) responsiveness of their anterior pituitaries (AP) to the ...

journal_title：Neuropsychobiology

authors： Brambilla F,Cocchi D,Nobile P,Müller EE

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Reaction time variability (RTV) is considered a valid endophenotype of attention deficit/hyperactivity disorder (ADHD). It is also often used to examine the efficacy of drug treatment or individual patients' treatment responses and has been furthermore suggested to significantly reduce the potential number o...

journal_title：Neuropsychobiology

authors： Grant P,Kuepper Y,Wielpuetz C,Hennig J

更新日期：2014-01-01 00:00:00

abstract：:The soporific effect of the neuroactive steroid pregnanolone, a metabolite of progesterone, and its relationship with plasma concentrations was assessed in 18 young, healthy, male volunteers for 2 h after administration of a single dose of pregnanolone prepared in two different formulations. Sedation was measured as s...

journal_title：Neuropsychobiology

authors： Schulz H,Jobert M,Gee KW,Ashbrook DW

更新日期：1996-01-01 00:00:00

abstract：:A considerable proportion of chronic non-organic pain patients suffer from insomnia, and alpha sleep has been suggested to be specifically associated with fibromyalgia. However, the clinical significance of those symptoms is not clear. This study was carried out to investigate this question. Twenty-six middle-aged, no...

journal_title：Neuropsychobiology

authors： Schneider-Helmert D,Whitehouse I,Kumar A,Lijzenga C

更新日期：2001-01-01 00:00:00

abstract：:This report presents the results of a retrospective analysis of pooled efficacy data from eight studies in which buspirone was compared to placebo in 520 patients with generalized anxiety disorder (GAD). In addition to evaluating overall efficacy in the composite patient data base, four criteria were used to identify ...

journal_title：Neuropsychobiology

authors： Gammans RE,Stringfellow JC,Hvizdos AJ,Seidehamel RJ,Cohn JB,Wilcox CS,Fabre LF,Pecknold JC,Smith WT,Rickels K

更新日期：1992-01-01 00:00:00

abstract：:77 primary depressive in-patients aged 18-70 years (mean = 46/47 years) were assigned randomly to experimental and control groups and treated in double-blind conditions in ten centers. Butriptyline and amitriptyline were both administered with an identical increasing schedule, up to 150 mg daily in the first week and ...

journal_title：Neuropsychobiology

authors： Guelfi JD,Dreyfus JF,Delcros M,Pichot P

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:We examined striatal dopamine transporter (DAT) binding in bipolar and unipolar depressed patients and compared these values to those obtained from healthy control subjects using the selective DAT radioligand [(99m)Tc]TRODAT-1 and single photon emission computed tomography imaging. We hypothesized that DAT le...

journal_title：Neuropsychobiology

authors： Amsterdam JD,Newberg AB

更新日期：2007-01-01 00:00:00

abstract：:The systematic recording of spontaneous electrodermal activity (EDA) on 23 normal subjects during 5 15-min sessions and the self-rating of anxious and/or depressive moods (Q-sort forced choice) shows a positive linear relationship between spontaneous EDA and anxious mood despite a low covariation between those two var...

journal_title：Neuropsychobiology

authors： de Bonis M,Baqué EF

更新日期：1978-01-01 00:00:00

abstract：:Time trends and periodic cycles in REM sleep eye movements were examined in 6 functional and 6 mongoloid adolescent retardates. Both groups of subjects showed approximately equal percentages of linear trends, quadratic trends, linear and quadratic trends, and absence of trend. The eye movement time-series were subject...

journal_title：Neuropsychobiology

authors： Krynicki V

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Derangements of the gut microbiome have been linked to increased systemic inflammation and central nervous system disorders, including schizophrenia. This systematic review thus aimed to investigate the hypothesis that probiotic supplementation improves schizophrenia symptoms. METHODS:By using the keywords ...

journal_title：Neuropsychobiology

authors： Ng QX,Soh AYS,Venkatanarayanan N,Ho CYX,Lim DY,Yeo WS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Although differences in symptom profiles and outcome between depressive patients with an underlying major depressive disorder (MDD) and bipolar depression (BD) have been reported, studies with sequential short-interval assessments in a real-life inpatient setting are scarce. OBJECTIVES:To examine potential ...

journal_title：Neuropsychobiology

authors： Hebbrecht K,Stuivenga M,Birkenhäger T,van der Mast RC,Sabbe B,Giltay EJ

更新日期：2020-01-01 00:00:00

abstract：:Gamma oscillations (>30 Hz) in the brain are involved in attention, perception and memory. They are altered in various pathological states, as well as by neuropharmaceuticals, so that they are of interest in drug and clinical investigations. However, when the human electroencephalogram is recorded on the scalp, this n...

journal_title：Neuropsychobiology

authors： Nottage JF,Horder J

更新日期：2015-01-01 00:00:00