Differentiating the effects of three benzodiazepines on non-REM sleep EEG spectra. A neural-network pattern classification analysis.

abstract：:Single, 50- and 100-mg oral doses of phenobarbital and a matching placebo were administered double-blind to 8 young, healthy male subjects. Multilead electroencephalographic (EEG) samples were recorded prior to, and at regular intervals within the 2 h following administration. The EEG signal was processed by power spe...

journal_title：Neuropsychobiology

authors： Sannita WG,Balbi A,Giacchino F,Rosadini G

更新日期：1990-01-01 00:00:00

abstract：:The present paper is a review of the use of psychophysiology in diagnosis and treatment of simple phobias. The paper begins with a definition and characterization of phobic fears, together with a description of prevalence rates, age onset, and gender differences. Acquisition is then discussed within a Three-Systems mo...

journal_title：Neuropsychobiology

authors： Hugdahl K

更新日期：1988-01-01 00:00:00

abstract：:A potential candidate gene that could contribute to the education process is the apolipoprotein E (apo E) gene that has been shown to correlate with memory function and memory decline. We measured apo E polymorphism in groups of probands with different levels of education selected from a population sample. In the grou...

journal_title：Neuropsychobiology

authors： Hubacek JA,Pitha J,Skodová Z,Adámková V,Lánská V,Poledne R

更新日期：2001-01-01 00:00:00

abstract：:In 63 depressed patients, the associations between severity of depression, psychomotor retardation, assessed by the Bech-Rafaelsen Melancholia Scale, and EEG spectral analysis were examined. Slow EEG activity (theta 2/alpha 1 bands) was positively and fast activity (alpha 3/beta bands) negatively correlated with the o...

journal_title：Neuropsychobiology

authors： Nieber D,Schlegel S

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Considerable evidence suggests that variation of the serotonin-transporter-linked promoter region (5- HTTLPR) is associated with anxiety-related traits. Academic outcomes are also more closely related to trait anxiety. This preliminary study aimed to explore the association between academic performance and l...

journal_title：Neuropsychobiology

authors： Calapoğlu M,Sahin-Calapoğlu N,Karaçöp A,Soyöz M,Elyıldırım UY,Avşaroğlu S

更新日期：2011-01-01 00:00:00

abstract：:This paper reports a replication study of a four-group cluster-analytic typology of depressed patients. Several hierarchial agglomerative clustering procedures were applied on the original patient sample using a slightly reduced variable pool. The best replication obtained used Ward's error sum of squares method and w...

journal_title：Neuropsychobiology

authors： Paykel ES,Henderson AJ

更新日期：1977-01-01 00:00:00

abstract：:Dopamine depletion induced by administration of Ro4-1284 produces a condition of rapid and repeated eye blinking in rats. This condition mimics the human disorder, blepharospasm, which often accompanies parkinsonism and other dopamine deficiency disorders. When given a 3-week course of a compound (SR-3) developed from...

journal_title：Neuropsychobiology

authors： Mostofsky DI,Yehuda S,Rabinovitz S,Carasso R

更新日期：2000-01-01 00:00:00

abstract：:Apomorphine, a dopamine receptor agonist (given in a dose of 0.75 mg s.c.), was administered to 8 healthy volunteers; electroencephalograph (EEG) and event-related potential (ERP) mapping were performed before dosing and 0.5, 1.5 and 2.5 h after dosing. Apomorphine caused an overall increase in beta activity at time 0...

journal_title：Neuropsychobiology

authors： Luthringer R,Rinaudo G,Toussaint M,Bailey P,Muller G,Muzet A,Macher J

更新日期：1999-01-01 00:00:00

abstract：:In humans and several other mammals, a quantitative EEG analysis has been used to study the regulation of sleep-wake behavior. In all mammalian species studied, cortical EEG recorded during non-REM sleep (NREMS) is characterized by the occurrence of spindles and high voltage, slow waves (0.5-4.0 Hz). Furthermore, slow...

journal_title：Neuropsychobiology

authors： Lancel M

更新日期：1993-01-01 00:00:00

abstract：:Analysis of the mechanisms underlying the clinical effects of different drugs is a vital part of psychopharmacology. It is fair to say, however, that such analyses have thus far met with little success. This lack of success can be traced to a variety of sources that have flawed the analytical process itself. Detailed ...

journal_title：Neuropsychobiology

authors： Carlton PL

更新日期：1984-01-01 00:00:00

abstract：:Individuals differ in hypnotizability. Information on hypnotizability-related EEG characteristics is controversial and incomplete, particularly on intracerebral source localization and EEG dimensionality. 19-channel, eyes-closed resting EEGs from right-handed, healthy, 8 high- and 4 low-hynotizable subjects (age: 26.7...

journal_title：Neuropsychobiology

authors： Isotani T,Lehmann D,Pascual-Marqui RD,Kochi K,Wackermann J,Saito N,Yagyu T,Kinoshita T,Sasada K

更新日期：2001-01-01 00:00:00

abstract：:Actions of the new antiepileptic drug lamotrigine (LTG) were characterized using extracellular and whole cell patch clamp recordings from rat CA1 and CA3 pyramidal cells in vitro. The results suggest that LTG, beside its previously described effect on the fast sodium inward current, also modulates - presumably voltage...

journal_title：Neuropsychobiology

authors： Grunze H,von Wegerer J,Greene RW,Walden J

更新日期：1998-10-01 00:00:00

abstract：:Schizophrenia is a heterogeneous and multidimensional disorder. The different syndromes or dimensions of this disorder represent distinct pathophysiological processes. Evidence is growing that each of the composite syndromes or dimensions of this disorder is associated with specific validators. This article reviewed n...

journal_title：Neuropsychobiology

authors： Aderibigbe YA,Gureje O

更新日期：1996-01-01 00:00:00

abstract：:The purpose of this study was to investigate the relationship between postoperative confusion and the plasma norepinephrine (NE), adrenocorticotropin (ACTH) or cortisol response to surgery in schizophrenic patients. We studied 50 schizophrenic patients and 35 control patients who underwent orthopedic surgery and perio...

journal_title：Neuropsychobiology

authors： Kudoh A,Takahira Y,Katagai H,Takazawa T

更新日期：2002-01-01 00:00:00

abstract：:Failure to gain weight during withdrawal from chronic regimens of dependence-producing drugs is observed in laboratory rats. Withdrawal from the benzodiazepine anxiolytic agent diazepam, whether induced by cessation of treatment or precipitated by administration of the specific benzodiazepine antagonist Ro-15,1788, is...

journal_title：Neuropsychobiology

authors： Eison MS

更新日期：1986-01-01 00:00:00

abstract：:The efficacy and safety of tianeptine were compared, in the course of a multicentre randomised, double-blind, parallel group study, to those of placebo in the treatment of Major Depressions and Bipolar Disorder, Depressed with or without melancholia, without psychotic features. After a 1-week run-in placebo period, 12...

journal_title：Neuropsychobiology

authors： Costa e Silva JA,Ruschel SI,Caetano D,Rocha FL,da Silva Lippi JR,Arruda S,Ozun M

更新日期：1997-01-01 00:00:00

abstract：:The analysis of the results obtained in different tests--sleep studies, cortical and hippocampal EEG activity, PGO-R spikes--in rats or in cats allows the characterization of different classes of drugs and to establish the relative efficacy of psychoactive drugs in these models. Moreover, the sequential spectral analy...

journal_title：Neuropsychobiology

authors： Depoortere H,Decobert M,Honoré L

更新日期：1983-01-01 00:00:00

abstract：:This study aimed to investigate the binding affinity of [3H]GABA and [3H]beta-alanine to GABA transporters GAT-1 and GAT-3 in the human dorsolateral prefrontal cortex (Brodmanns' area 9) in schizophrenia. Using post mortem tissue from individuals diagnosed with schizophrenia (n=6) and control subjects (n=6), the densi...

journal_title：Neuropsychobiology

authors： Schleimer SB,Hinton T,Dixon G,Johnston GA

更新日期：2004-01-01 00:00:00

abstract：:Like the industry, the medical profession takes now an interest in quality assurance programs. In the field of psychiatry, the quality assessment of antidepressive drug prescriptions is an ideal target. A brief review of previous studies reveals a high prevalence of the use of psychotropes among the general population...

journal_title：Neuropsychobiology

authors： Wilmotte J

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Panic disorder (PD) is a common and often chronic psychiatric condition that can lead to considerable disability in daily life. Using [(18)F]fluorodeoxyglucose-PET, we examined brain baseline glucose metabolism in PD patients in comparison with normal controls and the changes in glucose metabolism after 12 w...

journal_title：Neuropsychobiology

authors： Kang EH,Park JE,Lee KH,Cho YS,Kim JJ,Yu BH

更新日期：2012-01-01 00:00:00

abstract：:Recent findings indicate that the memory-impairing effects of benzodiazepines may preferentially involve the basolateral nucleus of the amygdala. To test this hypothesis we examined the effects on pretrial injection of diazepam into the central as compared to the lateral/basolateral amygdaloid nuclei on memory for a c...

journal_title：Neuropsychobiology

authors： Silva MA,Tomaz C

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Women have twice the rate of depression and anxiety disorders as men. Some studies suggest that this could be caused by women's greater sensitivity to negative emotions. Few brain imaging studies have compared the brain activity of men to women during a presentation of emotional stimuli. Our objective was to...

journal_title：Neuropsychobiology

authors： Thomas M,Gaudeau-Bosma C,Bouaziz N,Schenin-King Andrianisaina P,Benadhira R,Januel D,Moulier V

更新日期：2019-01-01 00:00:00

abstract：:A common polymorphism in the alpha1-antichymotrypsin (ACT) gene is associated with Alzheimer's disease. ACT is also a trophic factor in the hippocampal neurons. In order to examine if the ACT gene plays a role in the pathogenesis of schizophrenic disorders, patients (n = 175) and control subjects (n = 114) were genoty...

journal_title：Neuropsychobiology

authors： Chiu HJ,Hong CJ,Chen JY,Wang YC,Lin CY,Bai YM,Song HL,Lai HC,Tsai SJ

更新日期：1999-01-01 00:00:00

abstract：AIM:We describe the difficulties encountered in making a diagnosis where a somatic condition manifests itself alongside psychiatric symptoms associated with possible psychiatric comorbidities. METHODS:A case study is presented of a 15-year-old girl who was eventually diagnosed with ornithine transcarbamylase (OTC) def...

journal_title：Neuropsychobiology

authors： Niwinski P,Remberk B,Rybakowski F,Rokicki D

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:Rasagiline and selegiline are classified as monoamine oxidase B (MAO-B) inhibitors. The present investigation deals with time-dependent electrical frequency changes (electropharmacograms) induced by these, as well as by aminoindan, the major metabolite of rasagiline. METHOD:Adult rats (day-night converted, ...

journal_title：Neuropsychobiology

authors： Dimpfel W,Hoffmann JA

更新日期：2010-01-01 00:00:00

abstract：:Evidence from preclinical studies, preliminary clinical reports, pharmacologic challenge studies and a small number of controlled trials suggests that several antiepileptic agents--valproate, carbamazepine, and clonazepam--may have therapeutic effects in the treatment of patients with panic disorder. We review the the...

journal_title：Neuropsychobiology

authors： Keck PE Jr,McElroy SL,Tugrul KC,Bennett JA,Smith JM

更新日期：1993-01-01 00:00:00

abstract：:Intermittent short-lived episodes of depression were examined in a group of 20 recurrent suicidal attempters without major depression, classified misleadingly as borderline personality disorders on DSM-IIIR, during careful prospective follow-up for between 4 and 6 months. The duration of depressions clustered tightly ...

journal_title：Neuropsychobiology

authors： Montgomery SA,Montgomery D,Baldwin D,Green M

更新日期：1989-01-01 00:00:00

abstract：:During interictal periods in 9 patients with partial epilepsy we examined whether there were correlations between the relative power of background EEG (power spectral analysis) and the absolute values of regional cerebral blood flow (rCBF) measured by 99mTc hexamethylpropylene amine oxime (HMPAO) SPECT in each cerebra...

journal_title：Neuropsychobiology

authors： Jibiki I,Kurokawa K,Fukushima T,Kido H,Yamaguchi N,Matsuda H,Hisada K

更新日期：1994-01-01 00:00:00

abstract：:Two preliminary studies have indicated a variation in season of birth in severely language-disordered children. In the current study, the season of birth in 472 Danish children with language disorder born between 1958 and 1976 was compared with the season of birth of all Danish live-born children in the same period. F...

journal_title：Neuropsychobiology

authors： Hauschild KM,Mouridsen SE,Nielsen S

更新日期：2005-01-01 00:00:00

abstract：:Disturbances in the serotonergic neurotransmission system have been implicated in the etiology of attention deficit/hyperactivity disorder (ADHD). As the importance of genetic factors is well established, genes encoding for proteins of the serotonergic pathway are important candidates to unravel the underlying genetic...

journal_title：Neuropsychobiology

authors： Zoroglu SS,Erdal ME,Erdal N,Ozen S,Alasehirli B,Sivasli E

更新日期：2003-01-01 00:00:00