Symptom dimensions of schizophrenia: a selective integration of neurophysiological and neuropsychological correlates.

abstract：:Three anxiolytic drugs (bromazepam 3 mg, buspirone 10 mg, and clobazam 10 mg p.o.) were evaluated for their effects on memory, psychomotor performance and subjective response in a double-blind, placebo-controlled, crossover study in 20 healthy volunteers. At each session, measurements were made before and 2 and 6 h af...

journal_title：Neuropsychobiology

authors： Bourin M,Auget JL,Colombel MC,Larousse C

更新日期：1989-01-01 00:00:00

abstract：:Somatosensory event-related potentials (SERP) were recorded in 30 chronic young schizophrenic patients and in 15 age-matched controls. Objective SERP parameters were latencies, amplitudes and the determination of areas of the cognitive components N1 and P3 by integration. Highly significantly reduced areas and prolong...

journal_title：Neuropsychobiology

authors： Böning J,Drechsler F,Neuhauser B

更新日期：1989-01-01 00:00:00

abstract：:Symptoms of anxiety suggest autonomic dysfunction and most of the psychotropic agents used to treat anxiety and affective disorders have strong autonomic effects. This article describes the utility and importance of analysis of heart rate and blood pressure time series to study cardiac autonomic function in psychiatri...

journal_title：Neuropsychobiology

authors： Yeragani VK

更新日期：1995-01-01 00:00:00

abstract：:Nitric oxide (NO) has been implicated to play a role in the pathogenesis of depressive disorders. Adrenomedullin (AM) induces vasorelaxation by activating adenylate cyclase and also by stimulating the release of NO. AM immune reactivity is present in the brain, consistent with a role as neurotransmitter. Therefore, it...

journal_title：Neuropsychobiology

authors： Savaş HA,Herken H,Yürekli M,Uz E,Tutkun H,Zoroğlu SS,Ozen ME,Cengiz B,Akyol O

更新日期：2002-01-01 00:00:00

abstract：:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical import...

journal_title：Neuropsychobiology

authors： Refsum HE,Astrup C

更新日期：1980-01-01 00:00:00

abstract：:Cerebral impedance changes (F changes) indicating cerebral blood flow variations in the central and precentral areas were measured with a rheographic technique in normal subjects preparing for and carrying out a motor task. The time course of the F changes was studied and several significant correlations were establis...

journal_title：Neuropsychobiology

authors： Jacquy J,Piraux A,Jocquet P,Lhoas JP,Noel G

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND/AIMS:Suicidal behavior (SB) in bipolar disorder (BD) is a complex multifactorial event resulting from an interaction of genetic, neurobiological and psychosocial factors. Recent studies identified new possible mechanisms, suggesting a role for sirtuins (SIRTs 1-7), a family of nicotinamide adenine dinucleoti...

journal_title：Neuropsychobiology

authors： Nivoli A,Porcelli S,Albani D,Forloni G,Fusco F,Colom F,Vieta E,Serretti A

更新日期：2016-01-01 00:00:00

abstract：:7 women and 3 men with anorexia nervosa were tested with thyrotropin-releasing hormone (TRH) and luteinizing hormone-follicle stimulating hormone-releasing hormone (LH-RH) and the growth hormone (GH), prolactin (PRL), gonadotropin (FSH-LH) and thyrotropin (TSH) responsiveness of their anterior pituitaries (AP) to the ...

journal_title：Neuropsychobiology

authors： Brambilla F,Cocchi D,Nobile P,Müller EE

更新日期：1981-01-01 00:00:00

abstract：:Gamma-aminobutyric acid-B (GABAB) binding sites labelled with [3H]GABA were determined in postmortem frontal cortex samples of 20 control subjects and 16 suicides. The suicide group was further subdivided according to the method of suicide and the existence of depressive symptoms prior to death. No significant differe...

journal_title：Neuropsychobiology

authors： Arranz B,Cowburn R,Eriksson A,Vestling M,Marcusson J

更新日期：1992-01-01 00:00:00

abstract：:In two studies experimentally induced colds slowed the speed of response in a serial reaction task. Responding was also slower during the incubation period of the illness, which shows that performance on such a task may be used to predict subsequent illness. Volunteers who had no significant clinical illness, but who ...

journal_title：Neuropsychobiology

authors： Smith AP,Tyrrell DA,Al-Nakib W,Coyle KB,Donovan CB,Higgins PG,Willman JS

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Schizophrenia, a common neurological disorder appearing in the late teens or early adulthood, is characterized by disorganized thinking, behaviour, and perception of emotions. Aberrant N-methyl-D-aspartate (NMDA) receptor-mediated synaptic plasticity is a major pathological event here due to dysfunction of do...

journal_title：Neuropsychobiology

authors： Janardhanan A,Sadanand A,Vanisree AJ

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Corticotropin-releasing factor (CRF) plays a prominent role in mediating the effect of stressors on the hypothalamic-pituitary-adrenal axis. In this study, we examined the effects of chronic administration of second-generation antipsychotic drug ziprasidone on CRF mRNA expression in the hypothalamic paravent...

journal_title：Neuropsychobiology

authors： Park SW,Choi SM,Lee JG,Lee CH,Lee SJ,Kim NR,Kim YH

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:We examined striatal dopamine transporter (DAT) binding in bipolar and unipolar depressed patients and compared these values to those obtained from healthy control subjects using the selective DAT radioligand [(99m)Tc]TRODAT-1 and single photon emission computed tomography imaging. We hypothesized that DAT le...

journal_title：Neuropsychobiology

authors： Amsterdam JD,Newberg AB

更新日期：2007-01-01 00:00:00

abstract：:Single, 50- and 100-mg oral doses of phenobarbital and a matching placebo were administered double-blind to 8 young, healthy male subjects. Multilead electroencephalographic (EEG) samples were recorded prior to, and at regular intervals within the 2 h following administration. The EEG signal was processed by power spe...

journal_title：Neuropsychobiology

authors： Sannita WG,Balbi A,Giacchino F,Rosadini G

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Stress is a precipitating factor for both binge eating and bulimia nervosa (BN); however, the biological mechanisms through which it may trigger binge eating are poorly understood. There is evidence that the adrenal hormone cortisol and the gastric peptide ghrelin might be involved in stress-induced food ing...

journal_title：Neuropsychobiology

authors： Monteleone P,Tortorella A,Scognamiglio P,Serino I,Monteleone AM,Maj M

更新日期：2012-01-01 00:00:00

abstract：:The serotonergic system has been implicated in the production of the N1 and P2 components of auditory evoked potentials (AEPs). Moreover, studies have indicated the influence of heritability in the genesis of these AEP components. The serotonin transporter is the major site of serotonin reuptake into the presynaptic n...

journal_title：Neuropsychobiology

authors： Chen TJ,Yu YW,Chen MC,Tsai SJ,Hong CJ

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Deficits in psychological functioning, cognitive functioning, and sleep are frequently experienced by individuals who have survived aneurysmal subarachnoid haemorrhage (aSAH). Exercise has been shown to improve these domains; to date, it has never been explored in patients following aSAH. The aim of this exp...

journal_title：Neuropsychobiology

authors： Colledge F,Brand S,Pühse U,Holsboer-Trachsler E,Zimmerer S,Schleith R,Gerber M

更新日期：2017-01-01 00:00:00

abstract：:The influence of restraint stress on potential aluminum (Al)-induced behavioral changes was assessed in CD-1 mice. Three groups of adult mice were given 0, 300 and 600 mg Al/kg body weight per day in drinking water for 2 weeks. One-half of the animals in each group were concurrently subjected to restraint stress durin...

journal_title：Neuropsychobiology

authors： Colomina MT,Sanchez DJ,Sanchez-Turet M,Domingo JL

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Rasagiline and selegiline are classified as monoamine oxidase B (MAO-B) inhibitors. The present investigation deals with time-dependent electrical frequency changes (electropharmacograms) induced by these, as well as by aminoindan, the major metabolite of rasagiline. METHOD:Adult rats (day-night converted, ...

journal_title：Neuropsychobiology

authors： Dimpfel W,Hoffmann JA

更新日期：2010-01-01 00:00:00

abstract：:Hallucinogenic drug-induced states are considered as models for acute schizophrenic disorders (experimental psychoses). In a double-blind study with healthy volunteers we investigated the influence of the serotonergic hallucinogen psilocybin, the ecstasy-like drug 3,4-methylenedioxyethylamphetamine (MDE), the stimulan...

journal_title：Neuropsychobiology

authors： Gouzoulis-Mayfrank E,Thelen B,Maier S,Heekeren K,Kovar KA,Sass H,Spitzer M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Psychosis spectrum disorders, especially schizophrenia, have been linked to disturbed dopaminergic activity in the brain. Plasma homovanillic acid (pHVA) levels partly represent dopaminergic metabolism in the central nervous system. In the present study associations between (changes in) pHVA levels, symptom ...

journal_title：Neuropsychobiology

authors： van de Kerkhof NW,Fekkes D,van der Heijden FM,Egger JI,Verhoeven WM

更新日期：2015-01-01 00:00:00

abstract：:Monoamine oxidase A (MAOA) is a mitochondrial enzyme involved in the degradation of dopamine, serotonin and norepinephrine and these neurotransmitters are hypothesized to be involved in the cognitive function of humans. This study of a cohort of 191 healthy young Chinese females attempts to utilize the intelligence qu...

journal_title：Neuropsychobiology

authors： Yu YW,Tsai SJ,Hong CJ,Chen MC,Yang CW,Chen TJ

更新日期：2005-01-01 00:00:00

abstract：:We examined the chronic effects of desipramine and mianserin on increases of intracellular Ca2+ concentration ([Ca2+]i) induced by noradrenaline (NA), acetylcholine (ACh), or high K+ in cultured neurons of rat frontal cortex, using fluoromicroscopic analysis with Ca(2+)-sensitive dye fura-2. NA- and ACh-induced [Ca2+]...

journal_title：Neuropsychobiology

authors： Shimizu M,Nishida A,Fukuda H,Saito H,Yamawaki S

更新日期：1996-01-01 00:00:00

abstract：:Alcohol-dependent patients face a substantial risk of relapse after detoxification. Though psychosocial stress and coping strategies are regarded as major contributing factors in returning to drinking, the direct effects of coping styles on relapse are not clear. In this treatment outcome study, a mixed gender sample ...

journal_title：Neuropsychobiology

authors： Walter M,Gerhard U,Duersteler-MacFarland KM,Weijers HG,Boening J,Wiesbeck GA

更新日期：2006-01-01 00:00:00

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for many neurotransmitter receptors. Among the adverse effects of clozapine, urinary incontinence is commonly found and is suggested to be caused by alpha-adrenergic blockade. We tested the hypothesis that clozapine-induced urinary incontinence is...

journal_title：Neuropsychobiology

authors： Hsu JW,Wang YC,Lin CC,Bai YM,Chen JY,Chiu HJ,Tsai SJ,Hong CJ

更新日期：2000-01-01 00:00:00

abstract：:This report presents the results of a retrospective analysis of pooled efficacy data from eight studies in which buspirone was compared to placebo in 520 patients with generalized anxiety disorder (GAD). In addition to evaluating overall efficacy in the composite patient data base, four criteria were used to identify ...

journal_title：Neuropsychobiology

authors： Gammans RE,Stringfellow JC,Hvizdos AJ,Seidehamel RJ,Cohn JB,Wilcox CS,Fabre LF,Pecknold JC,Smith WT,Rickels K

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Lithium augmentation is a first-line strategy for depressed patients resistant to antidepressive therapy, but little is known about patients' subsequent long-term course or outcome predictors. We investigated long-term outcomes of unipolar depressed patients who had participated in a study on the effects of ...

journal_title：Neuropsychobiology

authors： Adli M,Bschor T,Bauer M,Lucka C,Lewitzka U,Ising M,Uhr M,Mueller-Oerlinghausen B,Baethge C

更新日期：2009-01-01 00:00:00

abstract：:Platelet 5-HT and plasma cortisol concentrations were determined in 59 schizophrenic patients with different time course of illness before and after dexamethasone suppression test (DST). An abnormal DST (nonsuppression) was observed in 51% of patients. In these patients basal cortisol and platelet 5-HT concentrations ...

journal_title：Neuropsychobiology

authors： Jakovljević M,Mück-Seler D,Pivac N,Crncević Z

更新日期：1998-01-01 00:00:00

abstract：:Cerebrospinal fluid (CSF) homovanillic acid, 5-hydroxyindoleacetic acid, 3-methoxy-4-hydroxyphenylglycol, and somatostatin and beta-endorphin levels were measured in 12 patients with panic disorder before and after 7 months of treatment with alprazolam or imipramine. The concentrations of CSF monoamine metabolites and...

journal_title：Neuropsychobiology

authors： Lepola U,Jolkkonen J,Rimón R,Riekkinen P

更新日期：1989-01-01 00:00:00

abstract：:Twelve healthy male volunteers received pyritinol 600 or 1,200 mg or placebo for 3 days according to a randomised, double-blind crossover design. On the 1st and 3rd days of each of the three treatment periods subjects completed a battery of psychological tests including Critical Flicker Fusion (CFFT), Choice Reaction ...

journal_title：Neuropsychobiology

authors： Hindmarch I,Coleston DM,Kerr JS

更新日期：1990-01-01 00:00:00