Effects of chronic exposure to desipramine and mianserin on Ca2+ mobilization induced by noradrenaline, acetylcholine, and high K+ in rat frontocortical neurons.

abstract：BACKGROUND:Abnormalities in different parameters of the norepinephrine system have been widely described in major depression. The presence of alpha(2)-adrenoreceptors in blood platelets, similar to those in the brain, prompted us to evaluate them in depressed patients, as compared with healthy controls. METHODS:Fiftee...

journal_title：Neuropsychobiology

authors： Marazziti D,Baroni S,Masala I,Di Nasso E,Giannaccini G,Betti L,Lucacchini A,Cassano GB

更新日期：2001-01-01 00:00:00

abstract：:Eight healthy paid male volunteers (age: 21-28 years, mean: 24.5 +/- 1.7 years; weight 62-79 kg) were administered via intravenous infusion (3 min) acute 25-, 50-, and 75-mg doses of phosphatidylserine, or matching placebo in a latin-square design. Multichannel EEG recordings were performed in baseline conditions, dur...

journal_title：Neuropsychobiology

authors： Rosadini G,Sannita WG,Nobili F,Cenacchi T

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The present study investigated the effects of rapid tryptophan depletion (RTD), and the ensuing reduction of central nervous system levels of serotonin (5-HT), upon reactive aggression in patients with attention deficit/hyperactivity disorder (ADHD). Furthermore, it was asked whether the relation between 5-H...

journal_title：Neuropsychobiology

authors： Stadler C,Zepf FD,Demisch L,Schmitt M,Landgraf M,Poustka F

更新日期：2007-01-01 00:00:00

abstract：:Evidence from preclinical studies, preliminary clinical reports, pharmacologic challenge studies and a small number of controlled trials suggests that several antiepileptic agents--valproate, carbamazepine, and clonazepam--may have therapeutic effects in the treatment of patients with panic disorder. We review the the...

journal_title：Neuropsychobiology

authors： Keck PE Jr,McElroy SL,Tugrul KC,Bennett JA,Smith JM

更新日期：1993-01-01 00:00:00

abstract：:The medical histories of a group of 511 patients hospitalized for schizophrenia were examined for the occurrence of perinatal distress. These patients were part of a 40-year follow-up study, so that their prognostic outcome was known at the time of this study. In this way, 200 cases of chronic schizophrenia were compa...

journal_title：Neuropsychobiology

authors： Wilcox JA,Nasrallah HA

更新日期：1987-01-01 00:00:00

abstract：:It is known that P-4502E1 metabolizes both ethanol and acetaldehyde, and that it can be induced after birth by inducers such as ethanol. Genetic polymorphisms in the 5'-flanking region change its transcriptional regulation. Persons who are either hetereozygous or mutant homozygous for CYP2E1 (C1/C2 or C2/C2) can drink...

journal_title：Neuropsychobiology

authors： Nakamura K,Iwahashi K,Ameno K,Sekine Y,Suzuki K,Minabe Y,Mori N

更新日期：2003-01-01 00:00:00

abstract：:In the present study, single-unit extracellular recording was used in male Wistar rats to compare the effects of a single dose (acute treatment) and a 21-day regimen (long-term treatment) with clomipramine (2.5 mg/kg) and fluoxetine (1.0 mg/kg) on the spontaneous firing rate of nucleus accumbens (NAcc) neurons connect...

journal_title：Neuropsychobiology

authors： Rodríguez-Landa JF,Contreras CM,Gutiérrez-García AG,Bernal-Morales B

更新日期：2003-01-01 00:00:00

abstract：:Platelet 5-HT and plasma cortisol concentrations were determined in 59 schizophrenic patients with different time course of illness before and after dexamethasone suppression test (DST). An abnormal DST (nonsuppression) was observed in 51% of patients. In these patients basal cortisol and platelet 5-HT concentrations ...

journal_title：Neuropsychobiology

authors： Jakovljević M,Mück-Seler D,Pivac N,Crncević Z

更新日期：1998-01-01 00:00:00

abstract：:The prevalence of 3,4-methylenedioxymethamphetamine (MDMA) use has increased globally and the pattern of consumption has changed considerably. Previously, a subculture of MDMA users was fairly restricted to the dance club scene. More recently, use has spread outside of this subculture and now many users consume MDMA f...

journal_title：Neuropsychobiology

authors： Schenk S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Valproic acid or valproate (VA) is an anticonvulsant and mood-stabilizing drug primarily used in the treatment of epilepsy and bipolar disorder. Ziprasidone (ZPN) is an atypical antipsychotic drug used mainly for the treatment of schizophrenia. METHODS:This study is a part of our investigation on the c...

journal_title：Neuropsychobiology

authors： Karapidaki I,Ekonomopoulou MT,Akritopoulou K,Anestakis D,Iakovidou-Kritsi Z

更新日期：2011-01-01 00:00:00

abstract：:Administration of progesterone produces sleep EEG patterns that resemble those of agonistic modulators at the GABAA receptor. Previous studies evaluating the effects of an oral progesterone administration on attention performance in females pointed to putative sedative effects of progesterone at high dosages. However,...

journal_title：Neuropsychobiology

authors： Grön G,Friess E,Herpers M,Rupprecht R

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Time of onset of antipsychotic action is still a debated matter. We aimed to replicate and extend previous findings that early response can predict subsequent non-response. METHODS:86 acutely psychotic patients treated with haloperidol were studied. RESULTS:A PANSS reduction ≤16% at 1 week predict...

journal_title：Neuropsychobiology

authors： Giegling I,Porcelli S,Balzarro B,Andrisano C,Schäfer M,Möller HJ,Rujescu D,Serretti A

更新日期：2012-01-01 00:00:00

abstract：:46 severely depressed inpatients received 10-hour intravenous infusions supplying a dose of 720 mg dibenzepin daily on 2 or some cases 3 successive days. The patients were kept under close psychiatric surveillance and their cardiovascular function was carefully monitored. The shorter infusions were as effective as inf...

journal_title：Neuropsychobiology

authors： Gastpar M,Cornu F,Faessler J,Haefliger A,Keller H,von Lerber W,Pagan J,Rem J

更新日期：1984-01-01 00:00:00

abstract：:We present a randomized double-blind study on the efficacy of caroverine in the treatment of alcohol withdrawal symptoms. The group B Ca2+ channel blocking agent caroverine was tested against meprobamate in inpatient treatment of alcohol withdrawal. Patients of both groups were similar in age, weight, duration of drin...

journal_title：Neuropsychobiology

authors： Koppi S,Eberhardt G,Haller R,König P

更新日期：1987-01-01 00:00:00

abstract：:A 56-year-old male parkinsonian patient developed a unique behavioral change following the oral administration of cinepazide, a cerebral vasodilator. This behavior consisted of an apparent infatuation with a ward nurse, which ceased after medication was discontinued. ...

journal_title：Neuropsychobiology

authors： Hashimoto A,Hanada M

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Stress is a precipitating factor for both binge eating and bulimia nervosa (BN); however, the biological mechanisms through which it may trigger binge eating are poorly understood. There is evidence that the adrenal hormone cortisol and the gastric peptide ghrelin might be involved in stress-induced food ing...

journal_title：Neuropsychobiology

authors： Monteleone P,Tortorella A,Scognamiglio P,Serino I,Monteleone AM,Maj M

更新日期：2012-01-01 00:00:00

abstract：:The focus is on evaluating the relationships between early behavioural problems and biochemical variables at adult age and their significance for early criminality and violent behaviour in a life perspective. In the present study, using prospective longitudinal data, a sample of males with a history of early criminal ...

journal_title：Neuropsychobiology

authors： Eklund J,Alm PO,af Klinteberg B

更新日期：2005-01-01 00:00:00

abstract：:Monoamine oxidase A (MAOA) is a mitochondrial enzyme involved in the degradation of dopamine, serotonin and norepinephrine and these neurotransmitters are hypothesized to be involved in the cognitive function of humans. This study of a cohort of 191 healthy young Chinese females attempts to utilize the intelligence qu...

journal_title：Neuropsychobiology

authors： Yu YW,Tsai SJ,Hong CJ,Chen MC,Yang CW,Chen TJ

更新日期：2005-01-01 00:00:00

abstract：:In humans and several other mammals, a quantitative EEG analysis has been used to study the regulation of sleep-wake behavior. In all mammalian species studied, cortical EEG recorded during non-REM sleep (NREMS) is characterized by the occurrence of spindles and high voltage, slow waves (0.5-4.0 Hz). Furthermore, slow...

journal_title：Neuropsychobiology

authors： Lancel M

更新日期：1993-01-01 00:00:00

abstract：:Electrovestibulography (EVestG) recordings have been previously applied toward classifying and/or measuring the severity of several neurological disorders including depression with and without anxiety. This study's objectives were to: (1) extract EVestG features representing physiological differences of healthy women ...

journal_title：Neuropsychobiology

authors： Lithgow BJ,Moussavi Z

更新日期：2017-01-01 00:00:00

abstract：:Plasma cortisol, catecholamine and cyclic AMP levels, response to dexamethasone suppression test and platelet MAO activity have been determined in 15 patients suffering from bipolar affective psychosis, each examined during a depressive, a manic and an euthymic phase, and in 15 sex- and age-matched normal controls. Me...

journal_title：Neuropsychobiology

authors： Maj M,Ariano MG,Arena F,Kemali D

更新日期：1984-01-01 00:00:00

abstract：:Suicide is one of the leading causes of death among adolescents worldwide. Studies on the seasonal pattern of youth suicides are rare and the results are very contradictory and heterogeneous. Generally, suicide methods affect the pattern of suicide seasonality. Shooting is the most common suicide method among Finnish ...

journal_title：Neuropsychobiology

authors： Lahti A,Räsänen P,Karvonen K,Särkioja T,Meyer-Rochow VB,Hakko H

更新日期：2006-01-01 00:00:00

abstract：:Neural-network pattern classifiers were used to study the effects of long half-life flurazepam (30 mg) and quazepam (15 mg), and short half-life triazolam (0.5 mg) on non-REM sleep. We measured the magnitude of effect, time course, and EEG spectral signature of the three benzodiazepines as a function of third-of-night...

journal_title：Neuropsychobiology

authors： Gevins AS,Stone RK,Ragsdale SD

更新日期：1988-01-01 00:00:00

abstract：:Possible age effects on binding of [(3)H]lysergic acid diethylamide ([(3)H]LSD) to serotonin 5-HT(2A) receptors and of [(3)H]paroxetine to serotonin uptake sites were studied in platelets from healthy children (11-12 years of age), adolescents (16-17 years of age) and adults. Significant overall age effects were found...

journal_title：Neuropsychobiology

authors： Sigurdh J,Spigset O,Allard P,Mjörndal T,Hägglöf B

更新日期：1999-11-01 00:00:00

abstract：:The aim of this paper was to determine whether the prolonged decrease in seizure threshold produced by chemical kindling was accompanied by behavioural changes in tests of anxiety and aggression. The responses of rats in five tests were examined after chronic treatment with the benzodiazepine inverse agonist FG7142. T...

journal_title：Neuropsychobiology

authors： Taylor SC,Johnston AL,Wilks LJ,Nicholass JM,File SE,Little HJ

更新日期：1988-01-01 00:00:00

abstract：:Cardiovascular measurements were used as indicators of autonomic arousal during an orthostatic challenge test without medication and after a test dose of 150 mg perazine in 20 acute schizophrenic patients. Unmedicated schizophrenics showed elevated heart rates and elevated systolic and diastolic blood pressure in comp...

journal_title：Neuropsychobiology

authors： Volz HP,Mackert A,Diefenbacher A,Friedrich A,Gaebel W,Müller H,Stock G,Möller HJ

更新日期：1994-01-01 00:00:00

abstract：:The relation between fasting, a.m. plasma prolactin and plasma/homovanillic acid (HVA) was studied in 9 healthy males on one occasion and in 9 healthy females on two occasions (in the follicular and luteal phase of the menstrual cycle). There was a significant inverse correlation between plasma HVA and plasma prolacti...

journal_title：Neuropsychobiology

authors： Roy-Byrne PP,Rubinow DR,Linnoila M

更新日期：1986-01-01 00:00:00

abstract：:Recent findings indicate that the memory-impairing effects of benzodiazepines may preferentially involve the basolateral nucleus of the amygdala. To test this hypothesis we examined the effects on pretrial injection of diazepam into the central as compared to the lateral/basolateral amygdaloid nuclei on memory for a c...

journal_title：Neuropsychobiology

authors： Silva MA,Tomaz C

更新日期：1995-01-01 00:00:00

abstract：:Saliva cortisol was measured at 11 p.m. in a sample of 74 psychiatric inpatients composed of 24 primary endogenous depressives, 40 secondary depressives and 20 nondepressives (DSM III and Saint-Louis criteria). Primary depressives had significantly higher 11 p.m. saliva cortisol levels than nondepressives (p less than...

journal_title：Neuropsychobiology

authors： Guéchot J,Lépine JP,Cohen C,Fiet J,Lempérière T,Dreux C

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:The failure to inhibit pleasurable but inappropriate urges is associated with frontal lobe pathology and has been suggested as a possible cause of pedophilic behavior. However, imaging and neuropsychological findings about frontal pathology in pedophilia are heterogeneous. In our study we therefore address i...

journal_title：Neuropsychobiology

authors： Habermeyer B,Esposito F,Händel N,Lemoine P,Kuhl HC,Klarhöfer M,Mager R,Mokros A,Dittmann V,Seifritz E,Graf M

更新日期：2013-01-01 00:00:00