A preliminary study of dopamine transporter binding in bipolar and unipolar depressed patients and healthy controls.

abstract：BACKGROUND:Lithium augmentation is a first-line strategy for depressed patients resistant to antidepressive therapy, but little is known about patients' subsequent long-term course or outcome predictors. We investigated long-term outcomes of unipolar depressed patients who had participated in a study on the effects of ...

journal_title：Neuropsychobiology

authors： Adli M,Bschor T,Bauer M,Lucka C,Lewitzka U,Ising M,Uhr M,Mueller-Oerlinghausen B,Baethge C

更新日期：2009-01-01 00:00:00

abstract：:Suicide is one of the leading causes of death among adolescents worldwide. Studies on the seasonal pattern of youth suicides are rare and the results are very contradictory and heterogeneous. Generally, suicide methods affect the pattern of suicide seasonality. Shooting is the most common suicide method among Finnish ...

journal_title：Neuropsychobiology

authors： Lahti A,Räsänen P,Karvonen K,Särkioja T,Meyer-Rochow VB,Hakko H

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:In general, humans tend to discount the value of delayed reward. An increase in the rate of discounting leads to an inability to select a delayed reward over a smaller immediate reward (reward-delay impulsivity). Although deficits in the serotonergic system are implicated in this reward-delay impulsivit...

journal_title：Neuropsychobiology

authors： Demoto Y,Okada G,Okamoto Y,Kunisato Y,Aoyama S,Onoda K,Munakata A,Nomura M,Tanaka SC,Schweighofer N,Doya K,Yamawaki S

更新日期：2012-01-01 00:00:00

abstract：:Six WHO Collaborating Centre took part in the study of the antithymic activity of blood sera of patients suffering from schizophrenia. Blood serum specimens from 118 schizophrenic patients and 62 mentally healthy donors were investigated. Statistically significant differences between schizophrenic patients and the con...

journal_title：Neuropsychobiology

authors： Koliaskina G,Tsutsulkovskaya M,Domashneva I,Maznina T,Kielholz P,Gastpar M,Bunney W,Rafaelsen O,Heltberg J,Coppen A,Hippius H,Hoecherl B,Vartanian F

更新日期：1980-01-01 00:00:00

abstract：:The author contended opposite pharmacological effects resulting from lithium and amphetamine. Three groups, each one consisting of four rats, were put on chronic lithium condition to measure its effects on amphetamine hyperactivity. This condition was effected after appropriate handling and saline control periods and ...

journal_title：Neuropsychobiology

authors： Flemenbaum A

更新日期：1975-01-01 00:00:00

abstract：:Prolactin (PRL) and growth hormone (GH) response to L-Dopa have been studied in 51 affectively ill women (26 unipolar and 25 bipolar) before and after amitriptyline treatment and in 14 normal female controls. There was no difference in GH response to L-dopa in all groups studied except for bipolar postmenopausal women...

journal_title：Neuropsychobiology

authors： Linkowski P,Brauman H,Mendlewicz J

更新日期：1983-01-01 00:00:00

abstract：:The present paper is a review of the use of psychophysiology in diagnosis and treatment of simple phobias. The paper begins with a definition and characterization of phobic fears, together with a description of prevalence rates, age onset, and gender differences. Acquisition is then discussed within a Three-Systems mo...

journal_title：Neuropsychobiology

authors： Hugdahl K

更新日期：1988-01-01 00:00:00

abstract：INTRODUCTION:REM sleep behavior disorder (RBD) is considered a prodromal phase of α-synucleinopathy like Parkinson disease (PD). PD is characterized by a progressive decline of dopamine (DA) in the striatum. Here we report the surprising increase in DA transporter density over successive years in an RBD patient treated...

journal_title：Neuropsychobiology

authors： Kunz D,Bes F

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Memory processes, as reflected by 'old/new' effects of event-related potentials (ERPs), have been shown to be impaired in depressed patients. This variability might be partly explained by biological factors. S100B is a glial calcium-binding protein with neuroplastic properties; S100B serum levels have been sh...

journal_title：Neuropsychobiology

authors： Zhang Y,Rothermundt M,Peters M,Wiesmann M,Hoy L,Arolt V,Emrich HM,Dietrich DE

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP), a marker of underlying low-grade inflammation, has been associated with the pathophysiology of bipolar disorder. Additionally, bipolar disorder may be accompanied by functional or structural cerebral alterations. We attempted to discover whether serum high-sensitivity CRP (hs-CRP) le...

journal_title：Neuropsychobiology

authors： Chung KH,Huang SH,Wu JY,Chen PH,Hsu JL,Tsai SY

更新日期：2013-01-01 00:00:00

abstract：:The effects of zolpidem or zaleplon on sleep architecture, respiratory patterns and performance were assessed at a simulated altitude of 4,000 m. Twelve male healthy subjects spent 4 nights in a decompression chamber, 1 at sea level (baseline), 3 at 4,000 m to test zolpidem (10 mg), zaleplon (10 mg) and placebo, given...

journal_title：Neuropsychobiology

authors： Beaumont M,Batéjat D,Coste O,Van Beers P,Colas A,Clère JM,Piérard C

更新日期：2004-01-01 00:00:00

abstract：:Sleep apnea is the most common sleep-related breathing disorder characterized by repetitive episodes of hypoxemia. Therapies include behavioral, surgical, orthodontic, pneumological, and pharmacological interventions. The aim of the present study was to compare the efficiency of pneumological therapy by nasal continuo...

journal_title：Neuropsychobiology

authors： Saletu B,Oberndorfer S,Anderer P,Gruber G,Divos H,Lachner A,Mandl M,Parapatics S,Popp W,Saletu M,Saletu-Zyhlarz G,Sertl K,Strobl R,Tschida U,Winkler A

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIMS:Heschl's gyrus (HG) is functionally involved in the genesis of auditory verbal hallucinations (AVH). This dysfunction seems to be structurally facilitated. The aim of the study was to analyze macrostructural features of HG in a group of patients reporting AVH who demonstrated white matter diffusion tens...

journal_title：Neuropsychobiology

authors： Hubl D,Dougoud-Chauvin V,Zeller M,Federspiel A,Boesch C,Strik W,Dierks T,Koenig T

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:Deficits in psychological functioning, cognitive functioning, and sleep are frequently experienced by individuals who have survived aneurysmal subarachnoid haemorrhage (aSAH). Exercise has been shown to improve these domains; to date, it has never been explored in patients following aSAH. The aim of this exp...

journal_title：Neuropsychobiology

authors： Colledge F,Brand S,Pühse U,Holsboer-Trachsler E,Zimmerer S,Schleith R,Gerber M

更新日期：2017-01-01 00:00:00

abstract：:Diabetes mellitus can induce impairment in learning and memory. Cognitive and memory deficits are common in older adults and especially in those with diabetes. This is mainly because of hyperglycemia, oxidative stress, and vascular abnormalities. Coenzyme Q10 (CoQ10) can decrease oxidative stress, hyperglycemia, and i...

journal_title：Neuropsychobiology

authors： Monsef A,Shahidi S,Komaki A

更新日期：2019-01-01 00:00:00

abstract：:Nitric oxide (NO) has been implicated to play a role in the pathogenesis of depressive disorders. Adrenomedullin (AM) induces vasorelaxation by activating adenylate cyclase and also by stimulating the release of NO. AM immune reactivity is present in the brain, consistent with a role as neurotransmitter. Therefore, it...

journal_title：Neuropsychobiology

authors： Savaş HA,Herken H,Yürekli M,Uz E,Tutkun H,Zoroğlu SS,Ozen ME,Cengiz B,Akyol O

更新日期：2002-01-01 00:00:00

abstract：:Recent findings indicate that the memory-impairing effects of benzodiazepines may preferentially involve the basolateral nucleus of the amygdala. To test this hypothesis we examined the effects on pretrial injection of diazepam into the central as compared to the lateral/basolateral amygdaloid nuclei on memory for a c...

journal_title：Neuropsychobiology

authors： Silva MA,Tomaz C

更新日期：1995-01-01 00:00:00

abstract：:The effects of lithium treatment on serotonin (5-HT) receptors in rat frontal cortex and hippocampus were investigated. Long-term lithium treatment strongly blocked 5-hydroxytryptophan-induced head twitches, while acute lithium administration by itself induced head twitches in rats, and ketanserin blocked this acute l...

journal_title：Neuropsychobiology

authors： Hotta I,Yamawaki S,Segawa T

更新日期：1986-01-01 00:00:00

abstract：:Renal lithium clearance and the serum lithium levels following a single oral loading dose of lithium were used as measures to predict lithium dose requirement during long-term maintenance at 3 different psychiatric centers in North America. Saliva lithium values were also investigated at one of the centers. The correl...

journal_title：Neuropsychobiology

authors： Tyrer SP,Grof P,Kalvar M,Shopsin B

更新日期：1981-01-01 00:00:00

abstract：:The performance on spatial and nonspatial associative learning tasks was tested in a sample of male drug-free DSM III-diagnosed schizophrenic patients and in a closely matched normal control group. Schizophrenics showed a worse performance on both versions of the task, but especially on the nonspatial one. A significa...

journal_title：Neuropsychobiology

authors： Kemali D,Maj M,Galderisi S,Monteleone P,Mucci A

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that altered immune responses play a role in the pathogenesis of autism spectrum disorders (ASD), together with dysfunction of the serotonergic and glutamatergic systems. Since the kynurenine (KYN) pathway that degrades tryptophan (TRP) is activated in various neuroinflammatory s...

journal_title：Neuropsychobiology

authors： Bryn V,Verkerk R,Skjeldal OH,Saugstad OD,Ormstad H

更新日期：2017-01-01 00:00:00

abstract：:The influence of restraint stress on potential aluminum (Al)-induced behavioral changes was assessed in CD-1 mice. Three groups of adult mice were given 0, 300 and 600 mg Al/kg body weight per day in drinking water for 2 weeks. One-half of the animals in each group were concurrently subjected to restraint stress durin...

journal_title：Neuropsychobiology

authors： Colomina MT,Sanchez DJ,Sanchez-Turet M,Domingo JL

更新日期：1999-09-01 00:00:00

abstract：:Substance P (SP) is a neuropeptide which is abundant in the periphery and the central nervous system, where it is colocalized with other neurotransmitters such as serotonin or dopamine. SP has been proposed to play a role in the regulation of pain including migraine and fibromyalgia, asthma, inflammatory bowel disease...

journal_title：Neuropsychobiology

authors： Lieb K,Treffurth Y,Berger M,Fiebich BL

更新日期：2002-01-01 00:00:00

abstract：:We report 3 patients who experienced nonconvulsive status epilepticus following generalized convulsions during antidepressant treatment. All showed prolonged confusion with some psychiatric symptoms, and their electroencephalograms (EEGs) showed either bilateral synchronous multiple spike wave discharges or continuous...

journal_title：Neuropsychobiology

authors： Yoshino A,Watanabe M,Shimizu K,Goto T,Ichinowatari N,Yoshimasu H,Masaki K,Aoyama T,Hara T

更新日期：1997-01-01 00:00:00

abstract：:To clarify the circadian aspects of delayed sleep phase syndrome (DSPS) in 4 patients with DSPS, we recorded polysomnograms and rectal temperature before and after chronotherapy. The time interval (2.7 h) between sleep onset and rectal temperature minimum before chronotherapy was shorter than the time interval after c...

journal_title：Neuropsychobiology

authors： Ozaki N,Iwata T,Itoh A,Kogawa S,Ohta T,Okada T,Kasahara Y

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Previous evidence suggested the possible association of FK506 binding protein 5 (FKBP5) gene variants in bipolar disorder (BPD). OBJECTIVE:Given the need of refinement of the findings obtained in large but poorly phenotyped samples, this study investigated the possible role of variants within FKBP5 in a sma...

journal_title：Neuropsychobiology

authors： Calabrò M,Crisafulli C,Di Nicola M,Colombo R,Janiri L,Serretti A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The availability of tobacco products is associated with the likelihood that adolescents will begin using tobacco. Yet the relationship between nicotine availability and voluntary consumption has not been tested experimentally in developing rats. METHOD:The impact of environmental availability on adolescent ...

journal_title：Neuropsychobiology

authors： Biondolillo KD,Pearce AR

更新日期：2007-01-01 00:00:00

abstract：AIMS:The aim was to measure the prefrontal cortical activity involved in shifting spatial attention to visual stimuli in the left or right visual field using near-infrared spectroscopy. METHODS:Eleven participants performed a simple vigilance task, an endogenous attention task and an exogenous attention task. In the e...

journal_title：Neuropsychobiology

authors： Takahashi M,Ikegami M

更新日期：2008-01-01 00:00:00

abstract：:In the search for differential mechanisms underlying clozapine's superior antipsychotic efficacy, the purinergic system has been considered, since an antagonist of the adenosine receptor A(2A) was shown to block clozapine acute effects on c-fos expression in rat striatum. Further investigating the interaction of cloza...

journal_title：Neuropsychobiology

authors： Lara DR,Vianna MR,de Paris F,Quevedo J,Oses JP,Battastini AM,Sarkis JJ,Souza DO

更新日期：2001-01-01 00:00:00

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for many neurotransmitter receptors. Among the adverse effects of clozapine, urinary incontinence is commonly found and is suggested to be caused by alpha-adrenergic blockade. We tested the hypothesis that clozapine-induced urinary incontinence is...

journal_title：Neuropsychobiology

authors： Hsu JW,Wang YC,Lin CC,Bai YM,Chen JY,Chiu HJ,Tsai SJ,Hong CJ

更新日期：2000-01-01 00:00:00