Substance P and affective disorders: new treatment opportunities by neurokinin 1 receptor antagonists?

abstract：OBJECTIVES:Deficits in psychological functioning, cognitive functioning, and sleep are frequently experienced by individuals who have survived aneurysmal subarachnoid haemorrhage (aSAH). Exercise has been shown to improve these domains; to date, it has never been explored in patients following aSAH. The aim of this exp...

journal_title：Neuropsychobiology

authors： Colledge F,Brand S,Pühse U,Holsboer-Trachsler E,Zimmerer S,Schleith R,Gerber M

更新日期：2017-01-01 00:00:00

abstract：:The relation between fasting, a.m. plasma prolactin and plasma/homovanillic acid (HVA) was studied in 9 healthy males on one occasion and in 9 healthy females on two occasions (in the follicular and luteal phase of the menstrual cycle). There was a significant inverse correlation between plasma HVA and plasma prolacti...

journal_title：Neuropsychobiology

authors： Roy-Byrne PP,Rubinow DR,Linnoila M

更新日期：1986-01-01 00:00:00

abstract：:Besides their regulation of the pituitary-adrenal and pituitary-thyroidal axis, respectively, the neurohormones CRH and TRH act within the central nervous system to evoke and modulate a number of behavioral and physiological processes. In particular, an increase in the sympathetic nervous system and respiratory activi...

journal_title：Neuropsychobiology

authors： Lehnert H,Nink M,Mann K,Röschke J,Hellhammer DH

更新日期：1993-01-01 00:00:00

abstract：:In humans and several other mammals, a quantitative EEG analysis has been used to study the regulation of sleep-wake behavior. In all mammalian species studied, cortical EEG recorded during non-REM sleep (NREMS) is characterized by the occurrence of spindles and high voltage, slow waves (0.5-4.0 Hz). Furthermore, slow...

journal_title：Neuropsychobiology

authors： Lancel M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Executive functions (EF) are often impaired in autism spectrum disorder (ASD). Such dysfunctions are associated with anxiety, depression, and a lack of autonomy. Transcranial direct current stimulation (tDCS) has been shown to enhance EF in healthy adults and clinical populations and to improve working memor...

journal_title：Neuropsychobiology

authors： Rothärmel M,Moulier V,Vasse M,Isaac C,Faerber M,Bendib B,Mirea-Grivel I,Opolczynski G,Rosier A,Guillin O

更新日期：2019-01-01 00:00:00

abstract：:In the past, some researchers found increased cortisol and prolactin responses to the administration of fenfluramine in major-depressed patients. It was believed that the fenfluramine test could prove to constitute another challenge probe to reflect the central serotonergic function. The present study was conducted in...

journal_title：Neuropsychobiology

authors： Maes M,Jacobs MP,Suy E,Minner B,Raus J

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:Olfactory processing depends on dopamine metabolism and orbitofrontal cortex functioning, both known to be disturbed in attention-deficit/hyperactivity disorder (ADHD). Some investigations suggested alterations in olfactory processing (identification and sensitivity) in childhood and adult ADHD. METHODS:In t...

journal_title：Neuropsychobiology

authors： Schecklmann M,Schenk E,Maisch A,Kreiker S,Jacob C,Warnke A,Gerlach M,Fallgatter AJ,Romanos M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The 5-hydroxytryptamine (5-HT) neurotransmitter system and lateral habenula (LHb) are involved in the regulation of depression, while the mechanisms remain to be clarified. OBJECTIVES:The effects and possible mecha-nism underlying activation or blockade of 5-HT4 receptors (5-HT4Rs) in the LHb in depression ...

journal_title：Neuropsychobiology

authors： Guo Y,Zhang L,Zhang J,Lv SX,Du CX,Wang T,Wang HS,Xie W,Liu J

更新日期：2020-07-14 00:00:00

abstract：BACKGROUND:Structural brain changes and cognitive impairments have been identified as indicators of genetic risk for schizophrenia. However, the pattern of associations between such structural and functional liability markers has been less well investigated. METHODS:Magnetic resonance imaging data and cognitive assess...

journal_title：Neuropsychobiology

authors： Habets P,Krabbendam L,Hofman P,Suckling J,Oderwald F,Bullmore E,Woodruff P,Van Os J,Marcelis M

更新日期：2008-01-01 00:00:00

abstract：:Cortisol has a modulatory influence on cognitive functions in humans. Both impairing and enhancing effects of cortisol administration have been shown for hippocampus-dependent declarative memory, and impairing effects have been shown for prefrontal-cortex-dependent working memory function. Given the high density of gl...

journal_title：Neuropsychobiology

authors： Kumsta R,Entringer S,Koper JW,van Rossum EF,Hellhammer DH,Wüst S

更新日期：2010-01-01 00:00:00

abstract：:Male Wistar rats were able to drink water and different percentages of ethyl alcohol in a free-choice paradigm. Our results showed a clear-cut preference for 2 and 3% ethanol concentration. Addition of quinine in both drinking bottles increased preference for alcohol, while dilution of saccharin in both bottles totall...

journal_title：Neuropsychobiology

authors： De Witte P

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Eugen Bleuler, in his book Dementia praecox oder Gruppe der Schizophrenien, discussed issues of social psychiatry, and he considered complex interventions pivotal in the care for people with schizophrenia. Bleuler emphasised the potential of therapeutic communities in providing care, the drawbacks of extende...

journal_title：Neuropsychobiology

authors： Becker T,Kösters M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Suicidal behavior (SB) in bipolar disorder (BD) is a complex multifactorial event resulting from an interaction of genetic, neurobiological and psychosocial factors. Recent studies identified new possible mechanisms, suggesting a role for sirtuins (SIRTs 1-7), a family of nicotinamide adenine dinucleoti...

journal_title：Neuropsychobiology

authors： Nivoli A,Porcelli S,Albani D,Forloni G,Fusco F,Colom F,Vieta E,Serretti A

更新日期：2016-01-01 00:00:00

abstract：:Gamma oscillations (>30 Hz) in the brain are involved in attention, perception and memory. They are altered in various pathological states, as well as by neuropharmaceuticals, so that they are of interest in drug and clinical investigations. However, when the human electroencephalogram is recorded on the scalp, this n...

journal_title：Neuropsychobiology

authors： Nottage JF,Horder J

更新日期：2015-01-01 00:00:00

abstract：:Individuals differ in hypnotizability. Information on hypnotizability-related EEG characteristics is controversial and incomplete, particularly on intracerebral source localization and EEG dimensionality. 19-channel, eyes-closed resting EEGs from right-handed, healthy, 8 high- and 4 low-hynotizable subjects (age: 26.7...

journal_title：Neuropsychobiology

authors： Isotani T,Lehmann D,Pascual-Marqui RD,Kochi K,Wackermann J,Saito N,Yagyu T,Kinoshita T,Sasada K

更新日期：2001-01-01 00:00:00

abstract：:The cerebrospinal fluid (CSF) concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) as well as their ratios and correlations were analyzed in relation to the season of birth. The sample consisted of 241 drug-free patients par...

journal_title：Neuropsychobiology

authors： Chotai J,Asberg M

更新日期：1999-01-01 00:00:00

abstract：:The effects of the addition of short-term lithium to long-term administration of antidepressants (clomipramine or citalopram) on the levels of 5-HT and 5-HIAA and serotonergic receptors were studied in the rat cortex. The addition of short-term Li to long-term antidepressant treatment potentiated an increase in 5-HIAA...

journal_title：Neuropsychobiology

authors： Okamoto Y,Motohasi N,Hayakawa H,Muraoka M,Yamawaki S

更新日期：1996-01-01 00:00:00

abstract：:Time trends and periodic cycles in REM sleep eye movements were examined in 6 functional and 6 mongoloid adolescent retardates. Both groups of subjects showed approximately equal percentages of linear trends, quadratic trends, linear and quadratic trends, and absence of trend. The eye movement time-series were subject...

journal_title：Neuropsychobiology

authors： Krynicki V

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:We examined striatal dopamine transporter (DAT) binding in bipolar and unipolar depressed patients and compared these values to those obtained from healthy control subjects using the selective DAT radioligand [(99m)Tc]TRODAT-1 and single photon emission computed tomography imaging. We hypothesized that DAT le...

journal_title：Neuropsychobiology

authors： Amsterdam JD,Newberg AB

更新日期：2007-01-01 00:00:00

abstract：AIM:We describe the difficulties encountered in making a diagnosis where a somatic condition manifests itself alongside psychiatric symptoms associated with possible psychiatric comorbidities. METHODS:A case study is presented of a 15-year-old girl who was eventually diagnosed with ornithine transcarbamylase (OTC) def...

journal_title：Neuropsychobiology

authors： Niwinski P,Remberk B,Rybakowski F,Rokicki D

更新日期：2020-07-20 00:00:00

abstract：:Behavioral abnormalities, jumping reaction, increase in spontaneous activity abnormal violence, and lethargy were observed in long-term ultraviolet A (UVA)-irradiated hairy male Crj:CD-1 mice. The learning ability of 6- and 12-months UVA-irradiated mice was significantly reduced compared to un-irradiated age-matched m...

journal_title：Neuropsychobiology

authors： Hiramoto K,Okada T,Ito M

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP), a marker of underlying low-grade inflammation, has been associated with the pathophysiology of bipolar disorder. Additionally, bipolar disorder may be accompanied by functional or structural cerebral alterations. We attempted to discover whether serum high-sensitivity CRP (hs-CRP) le...

journal_title：Neuropsychobiology

authors： Chung KH,Huang SH,Wu JY,Chen PH,Hsu JL,Tsai SY

更新日期：2013-01-01 00:00:00

abstract：:Cephalosporins may induce nonconvulsive status epilepticus (NCSE), a potentially reversible condition. Despite the wide use of these antibiotics, there are only few reported cases, because this condition is probably underestimated. We report two new cases of NCSE occurring during treatment with cefepime and ceftazidim...

journal_title：Neuropsychobiology

authors： Primavera A,Cocito L,Audenino D

更新日期：2004-01-01 00:00:00

abstract：:The International Pharmaco-EEG Society (IPEG) presents updated guidelines summarising the requirements for the recording and computerised evaluation of pharmaco-EEG data in man. Since the publication of the first pharmaco-EEG guidelines in 1982, technical and data processing methods have advanced steadily, thus enhanc...

journal_title：Neuropsychobiology

authors： Jobert M,Wilson FJ,Ruigt GS,Brunovsky M,Prichep LS,Drinkenburg WH,IPEG Pharmaco-EEG Guidelines Committee.

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND AIM:Repetitive transcranial magnetic stimulation (rTMS) is supposed to be not as effective in severe depression as it is in medium depression. We evaluated the treatment response to an ultra-high-frequency (UHF; 30 Hz) approach, which was used to maximize the rTMS efficacy in severely ill patients. METH...

journal_title：Neuropsychobiology

authors： Ullrich H,Kranaster L,Sigges E,Andrich J,Sartorius A

更新日期：2012-01-01 00:00:00

abstract：:This report presents the results of a retrospective analysis of pooled efficacy data from eight studies in which buspirone was compared to placebo in 520 patients with generalized anxiety disorder (GAD). In addition to evaluating overall efficacy in the composite patient data base, four criteria were used to identify ...

journal_title：Neuropsychobiology

authors： Gammans RE,Stringfellow JC,Hvizdos AJ,Seidehamel RJ,Cohn JB,Wilcox CS,Fabre LF,Pecknold JC,Smith WT,Rickels K

更新日期：1992-01-01 00:00:00

abstract：:It has been 60 years since Cade first described patients who responded to antimanic lithium treatment. Two decades later, responders to lithium stabilization emerged in larger numbers. The responses of many severely ill bipolar patients to lithium were striking and called for an explanation. Remarkable reactions to a ...

journal_title：Neuropsychobiology

authors： Grof P

更新日期：2010-01-01 00:00:00

abstract：:The purpose of this study was to investigate the relationship between postoperative confusion and the plasma norepinephrine (NE), adrenocorticotropin (ACTH) or cortisol response to surgery in schizophrenic patients. We studied 50 schizophrenic patients and 35 control patients who underwent orthopedic surgery and perio...

journal_title：Neuropsychobiology

authors： Kudoh A,Takahira Y,Katagai H,Takazawa T

更新日期：2002-01-01 00:00:00

abstract：:Somatosensory event-related potentials (SERP) were recorded in 30 chronic young schizophrenic patients and in 15 age-matched controls. Objective SERP parameters were latencies, amplitudes and the determination of areas of the cognitive components N1 and P3 by integration. Highly significantly reduced areas and prolong...

journal_title：Neuropsychobiology

authors： Böning J,Drechsler F,Neuhauser B

更新日期：1989-01-01 00:00:00

abstract：:Prolactin (PRL) and growth hormone (GH) response to L-Dopa have been studied in 51 affectively ill women (26 unipolar and 25 bipolar) before and after amitriptyline treatment and in 14 normal female controls. There was no difference in GH response to L-dopa in all groups studied except for bipolar postmenopausal women...

journal_title：Neuropsychobiology

authors： Linkowski P,Brauman H,Mendlewicz J

更新日期：1983-01-01 00:00:00