Naloxone reduces alcohol intake in a free-choice procedure even when both drinking bottles contain saccharin sodium or quinine substances.

abstract：:The systematic recording of spontaneous electrodermal activity (EDA) on 23 normal subjects during 5 15-min sessions and the self-rating of anxious and/or depressive moods (Q-sort forced choice) shows a positive linear relationship between spontaneous EDA and anxious mood despite a low covariation between those two var...

journal_title：Neuropsychobiology

authors： de Bonis M,Baqué EF

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:In depressed patients, overstimulation of the hypothalamo-pituitary-adrenocortical (HPA) system, probably caused by glucocorticoid receptor resistance, is the most consistent neurobiological finding. Glucocorticoids themselves are reported to increase leptin synthesis and secretion in humans. METHODS:We exa...

journal_title：Neuropsychobiology

authors： Himmerich H,Zimmermann P,Ising M,Kloiber S,Lucae S,Kunzel HE,Binder EB,Holsboer F,Uhr M

更新日期：2007-01-01 00:00:00

abstract：:Clinical observations have suggested that lithium may exert adverse effects on memory. The difficulty in achieving empirical consensus regarding this issue has reflected several methodological problems: diversity of research designs, heterogeneous samples, lack of control groups and the possible confounding of memory ...

journal_title：Neuropsychobiology

authors： Engelsmann F,Ghadirian AM,Grof P

更新日期：1992-01-01 00:00:00

abstract：:Hallucinogenic drug-induced states are considered as models for acute schizophrenic disorders (experimental psychoses). In a double-blind study with healthy volunteers we investigated the influence of the serotonergic hallucinogen psilocybin, the ecstasy-like drug 3,4-methylenedioxyethylamphetamine (MDE), the stimulan...

journal_title：Neuropsychobiology

authors： Gouzoulis-Mayfrank E,Thelen B,Maier S,Heekeren K,Kovar KA,Sass H,Spitzer M

更新日期：2002-01-01 00:00:00

abstract：:The author contended opposite pharmacological effects resulting from lithium and amphetamine. Three groups, each one consisting of four rats, were put on chronic lithium condition to measure its effects on amphetamine hyperactivity. This condition was effected after appropriate handling and saline control periods and ...

journal_title：Neuropsychobiology

authors： Flemenbaum A

更新日期：1975-01-01 00:00:00

abstract：:Recent studies suggest that the eye blink response to intense acoustic stimuli consists of two components that may occasionally result in waveforms with two peaks. In the present study, the prevalence, peak latencies, and peak magnitudes in responses exhibiting one or two peaks were investigated in healthy subjects in...

journal_title：Neuropsychobiology

authors： Meincke U,Light GA,Geyer MA,Braff DL

更新日期：2005-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled study the effect of nocturnal traffic noise and bedtime medication of a new benzodiazepine, OX-373, on objective and subjective sleep variables as well as on the quality of morning awakenings was investigated. 10 healthy subjects spent 17 nights in the sleep laboratory: 2 adaptati...

journal_title：Neuropsychobiology

authors： Saletu B,Grünberger J

更新日期：1981-01-01 00:00:00

abstract：:This paper reports a replication study of a four-group cluster-analytic typology of depressed patients. Several hierarchial agglomerative clustering procedures were applied on the original patient sample using a slightly reduced variable pool. The best replication obtained used Ward's error sum of squares method and w...

journal_title：Neuropsychobiology

authors： Paykel ES,Henderson AJ

更新日期：1977-01-01 00:00:00

abstract：:Like the industry, the medical profession takes now an interest in quality assurance programs. In the field of psychiatry, the quality assessment of antidepressive drug prescriptions is an ideal target. A brief review of previous studies reveals a high prevalence of the use of psychotropes among the general population...

journal_title：Neuropsychobiology

authors： Wilmotte J

更新日期：1989-01-01 00:00:00

abstract：:The popular recreational drug, (+/-)3, 4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') is a potent and selective brain serotonin (5-HT) neurotoxin in animals. MDMA-induced 5-HT neurotoxicity can be demonstrated using a variety of neurochemical, neuroanatomical and, more recently, functional measures of 5-HT neurons....

journal_title：Neuropsychobiology

authors： Ricaurte GA,Yuan J,McCann UD

更新日期：2000-01-01 00:00:00

abstract：:We present a randomized double-blind study on the efficacy of caroverine in the treatment of alcohol withdrawal symptoms. The group B Ca2+ channel blocking agent caroverine was tested against meprobamate in inpatient treatment of alcohol withdrawal. Patients of both groups were similar in age, weight, duration of drin...

journal_title：Neuropsychobiology

authors： Koppi S,Eberhardt G,Haller R,König P

更新日期：1987-01-01 00:00:00

abstract：:In the present study, the effects of short-acting benzodiazepines on nocturnal sleep and the carryover effects of these drugs were studied. The study involved 10 young, healthy male subjects who had given their written informed consent to participate. Either a placebo (PLA), 0.125 mg triazolam (TRZ), 0.25 mg TRZ or 0....

journal_title：Neuropsychobiology

authors： Suzuki H,Yamadera H,Asayama K,Kudo Y,Ito T,Tamura Y,Endo S

更新日期：2003-01-01 00:00:00

abstract：:In the past, some researchers found increased cortisol and prolactin responses to the administration of fenfluramine in major-depressed patients. It was believed that the fenfluramine test could prove to constitute another challenge probe to reflect the central serotonergic function. The present study was conducted in...

journal_title：Neuropsychobiology

authors： Maes M,Jacobs MP,Suy E,Minner B,Raus J

更新日期：1989-01-01 00:00:00

abstract：:Piracetam, when applied microiontophoretically and/or by hydropneumatic pump on the somatosensory cortex and hippocampus of the rat, affected neuronal activity by depressing or facilitating the spontaneous firing rate, depending on the area studied. Its effect were either additive or counteracting the actions of gluta...

journal_title：Neuropsychobiology

authors： Maillis A,Karayanidis F,Koutsoukos E,Angelopoulos E,Stefanis C

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:There is evidence that the nicotinic alpha7-acetylcholine receptor (alpha7-AChR) is involved in the pathophysiology of schizophrenia. Several neurotransmitter receptors, including alpha7-AChR, have been demonstrated on peripheral blood lymphocytes (PBL) and it has been suggested that these peripheral recepto...

journal_title：Neuropsychobiology

authors： Perl O,Strous RD,Dranikov A,Chen R,Fuchs S

更新日期：2006-01-01 00:00:00

abstract：:We agree with the conclusions of a recent article in this journal [James, Neuropsychobiology 1994;30:124-125] that studies on the psychoactive effects of caffeine need to take into account the possibility that the results obtained might represent merely the reversal of deleterious effects of caffeine deprivation rathe...

journal_title：Neuropsychobiology

authors： Rogers PJ,Richardson NJ,Dernoncourt C

更新日期：1995-01-01 00:00:00

abstract：:In obstructive sleep apnea patients, who intermittently stop breathing at night for some seconds, functions of vigilance and attention seem to be impaired. The aim of our study was to investigate if nocturnal hypoxia as one possible detrimental factor is associated with the degree of modality shift effect expressing a...

journal_title：Neuropsychobiology

authors： Gresele C,Hein H,Eggert F

更新日期：1998-01-01 00:00:00

abstract：:In the Lundby Study, all mental illnesses, treated as well as untreated, that occurred during a 25-year period in a geographically defined Swedish general population sample were evaluated. All forms of psychiatric services used by the population during the same period were registered. The present study investigates th...

journal_title：Neuropsychobiology

authors： Rorsman B,Hagnell O,Lanke J

更新日期：1983-01-01 00:00:00

abstract：:The effects of febarbamat and pipamperon on agitational and aggressive states of patients with diffuse psycho-organic syndrome were compared in a double-blind study on patients over 60 years of age requiring nursing care. Such disorders, particularly in the field of psychiatric gerontology, represent an increasing pro...

journal_title：Neuropsychobiology

authors： Brenner HD,Alberti L,Keller F,Schaffner L

更新日期：1984-01-01 00:00:00

abstract：:To clarify the role of the serotonergic system in limbic and thalamic epileptic activity, we examined the effects of 5-hydroxytryptophan (5-HTP, 20 and 40 mg/kg) on fully kindled seizures from the hippocampus and lateral geniculate nucleus. The intraperitoneal administration of 20 mg/kg 5-HTP exerted no anticonvulsant...

journal_title：Neuropsychobiology

authors： Wada Y,Hasegawa H,Nakamura M,Yamaguchi N

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Women have twice the rate of depression and anxiety disorders as men. Some studies suggest that this could be caused by women's greater sensitivity to negative emotions. Few brain imaging studies have compared the brain activity of men to women during a presentation of emotional stimuli. Our objective was to...

journal_title：Neuropsychobiology

authors： Thomas M,Gaudeau-Bosma C,Bouaziz N,Schenin-King Andrianisaina P,Benadhira R,Januel D,Moulier V

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Previous functional neuroimaging studies have reported that patients with schizophrenia show reduced prefrontal activation during cognitive tasks whereas patients with schizotypal personality disorder (SPD) show preserved or even increased right prefrontal activation, compared to healthy controls; on th...

journal_title：Neuropsychobiology

authors： Hori H,Nagamine M,Soshi T,Okabe S,Kim Y,Kunugi H

更新日期：2008-01-01 00:00:00

abstract：:The possible involvement of anxiety and learning/memory processes in escape-directed (struggling) behavior in a two-trial swimming test was investigated in mice, as well as the differential effects that low doses of flumazenil (a benzodiazepine receptor antagonist) could display depending on the animals' anxiety level...

journal_title：Neuropsychobiology

authors： Ferré P,Fernández Teruel A,Escorihuela RM,García E,Zapata A,Tobeña A

更新日期：1994-01-01 00:00:00

abstract：:Three anxiolytic drugs (bromazepam 3 mg, buspirone 10 mg, and clobazam 10 mg p.o.) were evaluated for their effects on memory, psychomotor performance and subjective response in a double-blind, placebo-controlled, crossover study in 20 healthy volunteers. At each session, measurements were made before and 2 and 6 h af...

journal_title：Neuropsychobiology

authors： Bourin M,Auget JL,Colombel MC,Larousse C

更新日期：1989-01-01 00:00:00

abstract：:Serotonergic dysfunction is implicated in Alzheimer's disease (AD) on the basis of studies of serotonin and its metabolite in postmortem specimens and CSF. There were also reports on association of a tryptophan hydroxylase (TPH) intron 7 variant and CSF 5-hydroxyindoleacetic acid concentrations. These suggested TPH mi...

journal_title：Neuropsychobiology

authors： Wang YC,Tsai SJ,Liu TY,Liu HC,Hong CJ

更新日期：2001-01-01 00:00:00

abstract：:Tetrahydrobiopterin (BH(4)) is a vital cofactor maintaining availability of the amine neurotransmitters [dopamine (DA), noradrenaline (NA), and serotonin (5-HT)], regulating the synthesis of nitric oxide (NO) by nitric oxide synthase (NOS), and stimulating and modulating the glutamatergic system (directly and indirect...

journal_title：Neuropsychobiology

authors： Richardson MA,Read LL,Taylor Clelland CL,Reilly MA,Chao HM,Guynn RW,Suckow RF,Clelland JD

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Previous results indicated a facilitated transcallosal inhibition via the corpus callosum (CC) in alexithymic male students. This study investigates transcallosal inhibition in alexithymic and nonalexithymic psychiatric inpatients. METHOD:Transcallosal inhibition was elicited by means of transcranial magneti...

journal_title：Neuropsychobiology

authors： Richter J,Möller B,Spitzer C,Letzel S,Bartols S,Barnow S,Willert C,Freyberger HJ,Grabe HJ

更新日期：2006-01-01 00:00:00

abstract：:Marked hostility toward relatives, therapists and friends is very frequently observed in anorexia nervosa (AN) as expression of outward-directed aggressiveness which interferes with the therapeutic programs of the patients. With the purpose to investigate this aspect of the disorder and its biological background, we s...

journal_title：Neuropsychobiology

authors： Brambilla F,Bellodi L,Arancio C,Limonta D,Ferrari E,Solerte B

更新日期：2001-01-01 00:00:00

abstract：:Serum dopamine-beta-hydroxylase (DBH) levels were assessed in 150 depressed patients of both sexes, with a mean age of 44.0 +/- 12.3 (SD) years. Patients were divided into unipolars (n = 46), bipolars (n = 25), neurotic-reactive (n = 46) and unspecified (n = 38) i.e., those who did not fit into any of the previous cat...

journal_title：Neuropsychobiology

authors： Eisemann M,Ericsson U,Von Knorring L,Perris C,Perris H,Ross S

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The present study investigated the effects of rapid tryptophan depletion (RTD), and the ensuing reduction of central nervous system levels of serotonin (5-HT), upon reactive aggression in patients with attention deficit/hyperactivity disorder (ADHD). Furthermore, it was asked whether the relation between 5-H...

journal_title：Neuropsychobiology

authors： Stadler C,Zepf FD,Demisch L,Schmitt M,Landgraf M,Poustka F

更新日期：2007-01-01 00:00:00