Abstract:
:Cephalosporins may induce nonconvulsive status epilepticus (NCSE), a potentially reversible condition. Despite the wide use of these antibiotics, there are only few reported cases, because this condition is probably underestimated. We report two new cases of NCSE occurring during treatment with cefepime and ceftazidime, and emphasize the utility of emergent electroencephalogram in patients with an acute altered state of consciousness while receiving treatment with cephalosporins, particularly when there is evidence of impaired renal function.
journal_name
Neuropsychobiologyjournal_title
Neuropsychobiologyauthors
Primavera A,Cocito L,Audenino Ddoi
10.1159/000077370keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
218-22issue
4eissn
0302-282Xissn
1423-0224pii
77370journal_volume
49pub_type
杂志文章abstract::In obstructive sleep apnea patients, who intermittently stop breathing at night for some seconds, functions of vigilance and attention seem to be impaired. The aim of our study was to investigate if nocturnal hypoxia as one possible detrimental factor is associated with the degree of modality shift effect expressing a...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000026505
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Derangements of the gut microbiome have been linked to increased systemic inflammation and central nervous system disorders, including schizophrenia. This systematic review thus aimed to investigate the hypothesis that probiotic supplementation improves schizophrenia symptoms. METHODS:By using the keywords ...
journal_title:Neuropsychobiology
pub_type: 杂志文章,meta分析
doi:10.1159/000498862
更新日期:2019-01-01 00:00:00
abstract::The concentrations of adenosine 3'5'-cyclic monophosphate (cyclic AMP) in cerebrospinal fluid (CSF) in manic-melancholic patients were studied. As control groups served patients suffering from other psychiatric disorders as well as neruological and orthopedic patients. The results showed no difference between the vari...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000117548
更新日期:1976-01-01 00:00:00
abstract::Failure to gain weight during withdrawal from chronic regimens of dependence-producing drugs is observed in laboratory rats. Withdrawal from the benzodiazepine anxiolytic agent diazepam, whether induced by cessation of treatment or precipitated by administration of the specific benzodiazepine antagonist Ro-15,1788, is...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118291
更新日期:1986-01-01 00:00:00
abstract::Marked hostility toward relatives, therapists and friends is very frequently observed in anorexia nervosa (AN) as expression of outward-directed aggressiveness which interferes with the therapeutic programs of the patients. With the purpose to investigate this aspect of the disorder and its biological background, we s...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章
doi:10.1159/000054894
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND/AIMS:Suicidal behavior (SB) in bipolar disorder (BD) is a complex multifactorial event resulting from an interaction of genetic, neurobiological and psychosocial factors. Recent studies identified new possible mechanisms, suggesting a role for sirtuins (SIRTs 1-7), a family of nicotinamide adenine dinucleoti...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000446921
更新日期:2016-01-01 00:00:00
abstract::The acute effects of alcohol (0.7 g/kg) on visual signal detection performance and critical flicker fusion frequency (CFF) of normal volunteers were investigated using a signal detection theory analysis. When signal probability was low, alcohol affected the stimulus sensitivity and the reaction times of hits. Under a ...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章
doi:10.1159/000118209
更新日期:1985-01-01 00:00:00
abstract::Recent findings indicate that the memory-impairing effects of benzodiazepines may preferentially involve the basolateral nucleus of the amygdala. To test this hypothesis we examined the effects on pretrial injection of diazepam into the central as compared to the lateral/basolateral amygdaloid nuclei on memory for a c...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000119209
更新日期:1995-01-01 00:00:00
abstract::Isolation causes important changes in the behavioral reactivity of rats to environmental stimuli. These changes include deficit in sensorimotor gating and altered fear-like responses to aversive stimuli. Measures of ultrasound vocalizations at 20-22 kHz when rats are exposed to threatening conditions, such as novelty,...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000085820
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES:Deficits in psychological functioning, cognitive functioning, and sleep are frequently experienced by individuals who have survived aneurysmal subarachnoid haemorrhage (aSAH). Exercise has been shown to improve these domains; to date, it has never been explored in patients following aSAH. The aim of this exp...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章
doi:10.1159/000486903
更新日期:2017-01-01 00:00:00
abstract::Changes of field potentials electrically evoked from the mesencephalon were studied in two dopaminergic target areas. The modulation of the responses in prefrontal cortex and striatum induced by intravenous injection of various compounds influencing central dopaminergic transmission is followed. In general, drugs with...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118200
更新日期:1985-01-01 00:00:00
abstract::This study was aimed to test the association between schizophrenia and a functional serotonin polymorphism (5-HTTLPR) in the upstream regulatory region. Genomic DNA analysis with polymerase chain reaction was used for 5-HTTLPR genotyping. One hundred and eleven patients with schizophrenia and 208 healthy individuals p...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000071212
更新日期:2003-01-01 00:00:00
abstract::This report presents the results of a retrospective analysis of pooled efficacy data from eight studies in which buspirone was compared to placebo in 520 patients with generalized anxiety disorder (GAD). In addition to evaluating overall efficacy in the composite patient data base, four criteria were used to identify ...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章,meta分析,随机对照试验
doi:10.1159/000118837
更新日期:1992-01-01 00:00:00
abstract::The aim of this paper was to determine whether the prolonged decrease in seizure threshold produced by chemical kindling was accompanied by behavioural changes in tests of anxiety and aggression. The responses of rats in five tests were examined after chronic treatment with the benzodiazepine inverse agonist FG7142. T...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118460
更新日期:1988-01-01 00:00:00
abstract::Little is known about the effects of cocaine on cognitive tasks. Event-related potentials (ERP) were recorded in 7 cocaine abusers during the performance of the auditory oddball task before and after the intravenous injections of saline and cocaine (60-80 mg). The P3B and slow wave components of the ERP were significa...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000119148
更新日期:1994-01-01 00:00:00
abstract::A double-blind comparison of zimeldine, a selective 5-HT reuptake inhibitor, and nomifensine, a noradrenaline and a dopamine reuptake inhibitor, was carried out in 43 inpatients with a scheduled treatment period of 6 weeks. All patients were diagnosed as definite major depressive disorder according to Research Diagnos...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章
doi:10.1159/000118086
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:There is increasing evidence that altered immune responses play a role in the pathogenesis of autism spectrum disorders (ASD), together with dysfunction of the serotonergic and glutamatergic systems. Since the kynurenine (KYN) pathway that degrades tryptophan (TRP) is activated in various neuroinflammatory s...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000488157
更新日期:2017-01-01 00:00:00
abstract::Peripheral benzodiazepine receptors (PBR) have been identified in peripheral organs as well as in brain glial cells. PBR differ from central benzodiazepine receptors (CBR) in their lack of coupling to the gamma-aminobutyric acid receptors and the chloride ion channels. We investigated the effect of 21 days administrat...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000026682
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Although differences in symptom profiles and outcome between depressive patients with an underlying major depressive disorder (MDD) and bipolar depression (BD) have been reported, studies with sequential short-interval assessments in a real-life inpatient setting are scarce. OBJECTIVES:To examine potential ...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000503686
更新日期:2020-01-01 00:00:00
abstract::Human personality traits, which are substantially heritable, may be modulated by monoamine neurotransmitters. It has been demonstrated that the catechol-O-methyltransferase (COMT) Val158Met genetic polymorphism, a functional polymorphism that may affect monoamine metabolism, is possibly associated with specific person...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000079107
更新日期:2004-01-01 00:00:00
abstract::The relationship between clinical effect of imipramine (IP) in 39 depressed patients and biochemical distinction, serum drug levels, and diagnostic classification was investigated retrospectively. Based on pretreatment plasma ratios of tryptophan and tyrosine to competing amino acids, which reflect the availability of...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118182
更新日期:1985-01-01 00:00:00
abstract::The prevalence of 3,4-methylenedioxymethamphetamine (MDMA) use has increased globally and the pattern of consumption has changed considerably. Previously, a subculture of MDMA users was fairly restricted to the dance club scene. More recently, use has spread outside of this subculture and now many users consume MDMA f...
journal_title:Neuropsychobiology
pub_type: 杂志文章,评审
doi:10.1159/000253549
更新日期:2009-01-01 00:00:00
abstract::The focus is on evaluating the relationships between early behavioural problems and biochemical variables at adult age and their significance for early criminality and violent behaviour in a life perspective. In the present study, using prospective longitudinal data, a sample of males with a history of early criminal ...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000087557
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:The availability of tobacco products is associated with the likelihood that adolescents will begin using tobacco. Yet the relationship between nicotine availability and voluntary consumption has not been tested experimentally in developing rats. METHOD:The impact of environmental availability on adolescent ...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000103905
更新日期:2007-01-01 00:00:00
abstract::The relationship between physical activity and mental health has been widely investigated, and several hypotheses have been formulated about it. Specifically, during the aging process, physical exercise might represent a potential adjunctive treatment for neuropsychiatric disorders and cognitive impairment, helping de...
journal_title:Neuropsychobiology
pub_type: 杂志文章,评审
doi:10.1159/000223730
更新日期:2009-01-01 00:00:00
abstract::10 long-term schizophrenic patients with tardive dyskinesia were studied over 14 weeks and maintained on their usual neuroleptic medications while anticholinergic antiparkinson drugs were employed and then discontinued, and the cycle then repeated. Discontinuation of anticholinergic medications resulted in improvement...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000117742
更新日期:1980-01-01 00:00:00
abstract::The author contended opposite pharmacological effects resulting from lithium and amphetamine. Three groups, each one consisting of four rats, were put on chronic lithium condition to measure its effects on amphetamine hyperactivity. This condition was effected after appropriate handling and saline control periods and ...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000117509
更新日期:1975-01-01 00:00:00
abstract::Quantitative assessment of regional cerebral blood flow (rCBF) was performed in a 22-year-old man with intractable temporal lobe epilepsy on long-term high-dose phenytoin (PHT) therapy, using single photon emission computed tomography (SPECT) with N-isopropyl-(iodine-123)-p-iodoamphetamine. In all the SPECT scans repe...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118982
更新日期:1993-01-01 00:00:00
abstract::Plasma levels of free and conjugated 3,4-dihydroxyphenylethyleneglycol (DOPEG), the main deaminated metabolite of norepinephrine, were assayed in 48 depressed patients before initiating a treatment with either maprotiline, an inhibitor of norepinephrine reuptake, or indalpine, a specific inhibitor of serotonin reuptak...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118243
更新日期:1986-01-01 00:00:00
abstract::The growing number of studies examining the relationship between suicide and lipid metabolism are based upon studies suggesting that cholesterol-lowering procedures may increase the risk of death due to suicide or impulsive-aggressive behavior. Leptin seems to be strongly associated with lipid metabolism. In the prese...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000054950
更新日期:2002-01-01 00:00:00