Adverse effects of anticholinergic antiparkinsonian drugs in tardive dyskinesia. An investigation of mechanism.

abstract：BACKGROUND:Oxytocin interacts with the dopaminergic system, which plays a role in addiction behaviors. The association between oxytocin and addiction was confirmed in animal studies. Novelty seeking is one of the predictors and indicators of drug addiction. The aim of the present study was to probe the association betw...

journal_title：Neuropsychobiology

authors： Lin SH,Lee LT,Tsai HC,Chen KC,Chen WT,Lee IH,Lu RB,Chen PS,Yang YK

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP), a marker of underlying low-grade inflammation, has been associated with the pathophysiology of bipolar disorder. Additionally, bipolar disorder may be accompanied by functional or structural cerebral alterations. We attempted to discover whether serum high-sensitivity CRP (hs-CRP) le...

journal_title：Neuropsychobiology

authors： Chung KH,Huang SH,Wu JY,Chen PH,Hsu JL,Tsai SY

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that altered immune responses play a role in the pathogenesis of autism spectrum disorders (ASD), together with dysfunction of the serotonergic and glutamatergic systems. Since the kynurenine (KYN) pathway that degrades tryptophan (TRP) is activated in various neuroinflammatory s...

journal_title：Neuropsychobiology

authors： Bryn V,Verkerk R,Skjeldal OH,Saugstad OD,Ormstad H

更新日期：2017-01-01 00:00:00

abstract：:Cerebrospinal fluid (CSF) homovanillic acid, 5-hydroxyindoleacetic acid, 3-methoxy-4-hydroxyphenylglycol, and somatostatin and beta-endorphin levels were measured in 12 patients with panic disorder before and after 7 months of treatment with alprazolam or imipramine. The concentrations of CSF monoamine metabolites and...

journal_title：Neuropsychobiology

authors： Lepola U,Jolkkonen J,Rimón R,Riekkinen P

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Executive functions (EF) are often impaired in autism spectrum disorder (ASD). Such dysfunctions are associated with anxiety, depression, and a lack of autonomy. Transcranial direct current stimulation (tDCS) has been shown to enhance EF in healthy adults and clinical populations and to improve working memor...

journal_title：Neuropsychobiology

authors： Rothärmel M,Moulier V,Vasse M,Isaac C,Faerber M,Bendib B,Mirea-Grivel I,Opolczynski G,Rosier A,Guillin O

更新日期：2019-01-01 00:00:00

abstract：:There is increasing evidence for an influence of directed attention on prepulse inhibition (PPI) of the acoustic startle reflex. However, the existing paradigms for the assessment of this effect have methodological problems and pitfalls. In particular, most previous studies used a paradigm which directed the attention...

journal_title：Neuropsychobiology

authors： Heekeren K,Meincke U,Geyer MA,Gouzoulis-Mayfrank E

更新日期：2004-01-01 00:00:00

abstract：:Several antipsychotics and antidepressants have been associated with electrocardiogram alterations, the most clinically relevant of which is the heart rate-corrected QT interval (QTc) prolongation, a risk factor for sudden cardiac death. Genetic variants influence drug-induced QTc prolongation and can provide valuable...

journal_title：Neuropsychobiology

authors： Corponi F,Fabbri C,Boriani G,Diemberger I,Albani D,Forloni G,Serretti A

更新日期：2019-01-01 00:00:00

abstract：:The search for specific predepressive personality factors has a long tradition in psychiatry. Studies in which assessments were made prospectively, before the onset of a first-ever episode of the illness, are, however, rare. In the present report from the Lundby Study we have investigated premorbid, mainly personality...

journal_title：Neuropsychobiology

authors： Rorsman B,Gräsbeck A,Hagnell O,Isberg PE,Otterbeck L

更新日期：1993-01-01 00:00:00

abstract：:Growth hormone (GH) possesses multiple metabolic effects, in particular with regard to glucose and lipid homeostasis. Studies on the effects of GH on body weight and food and water intake are scarce and have yielded controversial results. We investigated the effects of different modes of GH administration on the param...

journal_title：Neuropsychobiology

authors： Schulz C,Wieczorek I,Reschke K,Lehnert H

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND/AIMS:Neurotrophins such as brain-derived neurotrophic factor (BDNF) are vital for neuronal survival and adaptive plasticity. With high BDNF gene expression in the prefrontal cortex, BDNF is a potential regulatory factor for building and maintaining cognitive reserves. Recent studies suggest that individual d...

journal_title：Neuropsychobiology

authors： Koven NS,Collins LR

更新日期：2014-01-01 00:00:00

abstract：:A potential candidate gene that could contribute to the education process is the apolipoprotein E (apo E) gene that has been shown to correlate with memory function and memory decline. We measured apo E polymorphism in groups of probands with different levels of education selected from a population sample. In the grou...

journal_title：Neuropsychobiology

authors： Hubacek JA,Pitha J,Skodová Z,Adámková V,Lánská V,Poledne R

更新日期：2001-01-01 00:00:00

abstract：:The focus is on evaluating the relationships between early behavioural problems and biochemical variables at adult age and their significance for early criminality and violent behaviour in a life perspective. In the present study, using prospective longitudinal data, a sample of males with a history of early criminal ...

journal_title：Neuropsychobiology

authors： Eklund J,Alm PO,af Klinteberg B

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Rasagiline and selegiline are classified as monoamine oxidase B (MAO-B) inhibitors. The present investigation deals with time-dependent electrical frequency changes (electropharmacograms) induced by these, as well as by aminoindan, the major metabolite of rasagiline. METHOD:Adult rats (day-night converted, ...

journal_title：Neuropsychobiology

authors： Dimpfel W,Hoffmann JA

更新日期：2010-01-01 00:00:00

abstract：:The concentrations of adenosine 3'5'-cyclic monophosphate (cyclic AMP) in cerebrospinal fluid (CSF) in manic-melancholic patients were studied. As control groups served patients suffering from other psychiatric disorders as well as neruological and orthopedic patients. The results showed no difference between the vari...

journal_title：Neuropsychobiology

authors： Geisler A,Bech P,Johannesen M,Rafaelsen OJ

更新日期：1976-01-01 00:00:00

abstract：:Nitric oxide (NO) has been implicated to play a role in the pathogenesis of depressive disorders. Adrenomedullin (AM) induces vasorelaxation by activating adenylate cyclase and also by stimulating the release of NO. AM immune reactivity is present in the brain, consistent with a role as neurotransmitter. Therefore, it...

journal_title：Neuropsychobiology

authors： Savaş HA,Herken H,Yürekli M,Uz E,Tutkun H,Zoroğlu SS,Ozen ME,Cengiz B,Akyol O

更新日期：2002-01-01 00:00:00

abstract：:An electric potential measurement tells us only about the difference between two electrode locations. When prior experiments or present measurements prove that an electrode's location is inactive (especially in 'mono-polar' or scalp-to-reference technique), then EEG records and EEG maps can be interpreted regionally n...

journal_title：Neuropsychobiology

authors： Walter DO,Etevenon P,Pidoux B,Tortrat D,Guillou S

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND/AIMS/METHODS:Electroconvulsive therapy (ECT) is still one of the most potent treatments in the acute phase of major depressive disorder (MDD) and particularly applied in patients considered treatment resistant. However, despite the frequent and widespread use of ECT for >70 years, the exact neurobiological m...

journal_title：Neuropsychobiology

authors： Stippl A,Kirkgöze FN,Bajbouj M,Grimm S

更新日期：2020-01-01 00:00:00

abstract：:The purpose of this study was to investigate the relationship between postoperative confusion and the plasma norepinephrine (NE), adrenocorticotropin (ACTH) or cortisol response to surgery in schizophrenic patients. We studied 50 schizophrenic patients and 35 control patients who underwent orthopedic surgery and perio...

journal_title：Neuropsychobiology

authors： Kudoh A,Takahira Y,Katagai H,Takazawa T

更新日期：2002-01-01 00:00:00

abstract：:Twelve healthy male volunteers received pyritinol 600 or 1,200 mg or placebo for 3 days according to a randomised, double-blind crossover design. On the 1st and 3rd days of each of the three treatment periods subjects completed a battery of psychological tests including Critical Flicker Fusion (CFFT), Choice Reaction ...

journal_title：Neuropsychobiology

authors： Hindmarch I,Coleston DM,Kerr JS

更新日期：1990-01-01 00:00:00

abstract：:Serum dopamine-beta-hydroxylase (DBH) levels were assessed in 150 depressed patients of both sexes, with a mean age of 44.0 +/- 12.3 (SD) years. Patients were divided into unipolars (n = 46), bipolars (n = 25), neurotic-reactive (n = 46) and unspecified (n = 38) i.e., those who did not fit into any of the previous cat...

journal_title：Neuropsychobiology

authors： Eisemann M,Ericsson U,Von Knorring L,Perris C,Perris H,Ross S

更新日期：1983-01-01 00:00:00

abstract：:Behavioral abnormalities, jumping reaction, increase in spontaneous activity abnormal violence, and lethargy were observed in long-term ultraviolet A (UVA)-irradiated hairy male Crj:CD-1 mice. The learning ability of 6- and 12-months UVA-irradiated mice was significantly reduced compared to un-irradiated age-matched m...

journal_title：Neuropsychobiology

authors： Hiramoto K,Okada T,Ito M

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:Patients with bulimia nervosa (BN) are reported to have decreased postprandial levels of cholecystokinin (CCK) and peptide YY (PYY). Fatty nutrients are the most powerful stimulus for releasing these peptides. Cholestyramine is an anion exchanger which adsorbs bile salts and reduces the digestion of lipids, a...

journal_title：Neuropsychobiology

authors： Rigamonti AE,Sartorio A,Scognamiglio P,Bini S,Monteleone AM,Mastromo D,Marazzi N,Cella SG,Monteleone P

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Although differences in symptom profiles and outcome between depressive patients with an underlying major depressive disorder (MDD) and bipolar depression (BD) have been reported, studies with sequential short-interval assessments in a real-life inpatient setting are scarce. OBJECTIVES:To examine potential ...

journal_title：Neuropsychobiology

authors： Hebbrecht K,Stuivenga M,Birkenhäger T,van der Mast RC,Sabbe B,Giltay EJ

更新日期：2020-01-01 00:00:00

abstract：:77 primary depressive in-patients aged 18-70 years (mean = 46/47 years) were assigned randomly to experimental and control groups and treated in double-blind conditions in ten centers. Butriptyline and amitriptyline were both administered with an identical increasing schedule, up to 150 mg daily in the first week and ...

journal_title：Neuropsychobiology

authors： Guelfi JD,Dreyfus JF,Delcros M,Pichot P

更新日期：1983-01-01 00:00:00

abstract：:Possible age effects on binding of [(3)H]lysergic acid diethylamide ([(3)H]LSD) to serotonin 5-HT(2A) receptors and of [(3)H]paroxetine to serotonin uptake sites were studied in platelets from healthy children (11-12 years of age), adolescents (16-17 years of age) and adults. Significant overall age effects were found...

journal_title：Neuropsychobiology

authors： Sigurdh J,Spigset O,Allard P,Mjörndal T,Hägglöf B

更新日期：1999-11-01 00:00:00

abstract：:Previously, we performed an MRI study that revealed smaller volumes of the subregions of the cerebellar vermis in men and women with chronic schizophrenia. An issue that arose from that study was whether similar structural changes in the cerebellum are found in patients with first-episode schizophrenia. In the present...

journal_title：Neuropsychobiology

authors： Okugawa G,Nobuhara K,Takase K,Kinoshita T

更新日期：2007-01-01 00:00:00

abstract：:The aim of this paper was to determine whether the prolonged decrease in seizure threshold produced by chemical kindling was accompanied by behavioural changes in tests of anxiety and aggression. The responses of rats in five tests were examined after chronic treatment with the benzodiazepine inverse agonist FG7142. T...

journal_title：Neuropsychobiology

authors： Taylor SC,Johnston AL,Wilks LJ,Nicholass JM,File SE,Little HJ

更新日期：1988-01-01 00:00:00

abstract：:Dysfunctional mechanisms in the serotonergic system have been implicated in suicidal behavior among patients with schizophrenia. However, previous association analyses of major serotonin genes have provided inconsistent findings regarding their role in suicidal behavior. The goal of the current study was to identify s...

journal_title：Neuropsychobiology

authors： Bani-Fatemi A,Howe AS,Matmari M,Koga A,Zai C,Strauss J,De Luca V

更新日期：2016-01-01 00:00:00

abstract：:The relationship between physical activity and mental health has been widely investigated, and several hypotheses have been formulated about it. Specifically, during the aging process, physical exercise might represent a potential adjunctive treatment for neuropsychiatric disorders and cognitive impairment, helping de...

journal_title：Neuropsychobiology

authors： Deslandes A,Moraes H,Ferreira C,Veiga H,Silveira H,Mouta R,Pompeu FA,Coutinho ES,Laks J

更新日期：2009-01-01 00:00:00

abstract：:Like the industry, the medical profession takes now an interest in quality assurance programs. In the field of psychiatry, the quality assessment of antidepressive drug prescriptions is an ideal target. A brief review of previous studies reveals a high prevalence of the use of psychotropes among the general population...

journal_title：Neuropsychobiology

authors： Wilmotte J

更新日期：1989-01-01 00:00:00