Interaction between Methylation and CpG Single-Nucleotide Polymorphisms in the HTR2A Gene: Association Analysis with Suicide Attempt in Schizophrenia.

abstract：BACKGROUND AND AIM:Repetitive transcranial magnetic stimulation (rTMS) is supposed to be not as effective in severe depression as it is in medium depression. We evaluated the treatment response to an ultra-high-frequency (UHF; 30 Hz) approach, which was used to maximize the rTMS efficacy in severely ill patients. METH...

journal_title：Neuropsychobiology

authors： Ullrich H,Kranaster L,Sigges E,Andrich J,Sartorius A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Previous functional neuroimaging studies have reported that patients with schizophrenia show reduced prefrontal activation during cognitive tasks whereas patients with schizotypal personality disorder (SPD) show preserved or even increased right prefrontal activation, compared to healthy controls; on th...

journal_title：Neuropsychobiology

authors： Hori H,Nagamine M,Soshi T,Okabe S,Kim Y,Kunugi H

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Disgust is a basic emotion that involves feelings of revulsion and withdrawal behavior from dangerous/infectious situations. Very little is known about the genetic basis of disgust sensitivity. The dopamine receptor D4 (DRD4) and catechol-O-methyltransferase (COMT) genes have been implicated in neuroticism-r...

journal_title：Neuropsychobiology

authors： Kang JI,Kim SJ,Namkoong K,An SK

更新日期：2010-01-01 00:00:00

abstract：:The search for specific predepressive personality factors has a long tradition in psychiatry. Studies in which assessments were made prospectively, before the onset of a first-ever episode of the illness, are, however, rare. In the present report from the Lundby Study we have investigated premorbid, mainly personality...

journal_title：Neuropsychobiology

authors： Rorsman B,Gräsbeck A,Hagnell O,Isberg PE,Otterbeck L

更新日期：1993-01-01 00:00:00

abstract：:The performance on spatial and nonspatial associative learning tasks was tested in a sample of male drug-free DSM III-diagnosed schizophrenic patients and in a closely matched normal control group. Schizophrenics showed a worse performance on both versions of the task, but especially on the nonspatial one. A significa...

journal_title：Neuropsychobiology

authors： Kemali D,Maj M,Galderisi S,Monteleone P,Mucci A

更新日期：1987-01-01 00:00:00

abstract：:Both thyrotropin-releasing hormone (TRH) and amphetamine antagonize pentobarbital. They are more effective in the day than at night. This is true for TRH even when the dose of pentobarbital is increased at night to prolong sedation. Under this condition the day-night difference is lost for amphetamine. Both substances...

journal_title：Neuropsychobiology

authors： Prange AJ Jr,Breese GR,Jahnke GD,Cooper BR,Cott JM,Wilson IC,Lipton MA,Plotnikoff NP

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Patients with bipolar disorder are at a high risk for becoming obese. Adipokines are associated with depression and obesity via the inflammatory process. However, few studies have investigated the associations between depression and leptin, adiponectin and resistin levels in patients with bipolar disorder. W...

journal_title：Neuropsychobiology

authors： Lee HJ,Kim SH,Kim EY,Lee NY,Yu HY,Kim YS,Ahn YM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Structural brain changes and cognitive impairments have been identified as indicators of genetic risk for schizophrenia. However, the pattern of associations between such structural and functional liability markers has been less well investigated. METHODS:Magnetic resonance imaging data and cognitive assess...

journal_title：Neuropsychobiology

authors： Habets P,Krabbendam L,Hofman P,Suckling J,Oderwald F,Bullmore E,Woodruff P,Van Os J,Marcelis M

更新日期：2008-01-01 00:00:00

abstract：:The lithium RBC/plasma ratio was determined in 59 patients during prophylactic lithium therapy -- 10 cycloid psychotics, 28 unipolars and 21 bipolars -- as well as in 20 patients during lithium therapy in phase of illness -- 8 cycloid psychotics, 5 unipolars and 7 bipolars. The lithium ratio was found to be normally d...

journal_title：Neuropsychobiology

authors： von Knorring L,Oreland L,Perris C,Runeberg S

更新日期：1976-01-01 00:00:00

abstract：:In contrast to the single-channel dimensional complexity, the global dimensional complexity is calculated from a multichannel EEG. The intention with the method is to measure the spatial distribution of information processing in the brain. The method seems to be of interest in psychopharmacological research, but the i...

journal_title：Neuropsychobiology

authors： Matousek M,Wackermann J,Palus M,Berankova A,Albrecht V,Dvorak I

更新日期：1995-01-01 00:00:00

abstract：:This study aimed to investigate the binding affinity of [3H]GABA and [3H]beta-alanine to GABA transporters GAT-1 and GAT-3 in the human dorsolateral prefrontal cortex (Brodmanns' area 9) in schizophrenia. Using post mortem tissue from individuals diagnosed with schizophrenia (n=6) and control subjects (n=6), the densi...

journal_title：Neuropsychobiology

authors： Schleimer SB,Hinton T,Dixon G,Johnston GA

更新日期：2004-01-01 00:00:00

abstract：:The effects of febarbamat and pipamperon on agitational and aggressive states of patients with diffuse psycho-organic syndrome were compared in a double-blind study on patients over 60 years of age requiring nursing care. Such disorders, particularly in the field of psychiatric gerontology, represent an increasing pro...

journal_title：Neuropsychobiology

authors： Brenner HD,Alberti L,Keller F,Schaffner L

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:There is evidence that the nicotinic alpha7-acetylcholine receptor (alpha7-AChR) is involved in the pathophysiology of schizophrenia. Several neurotransmitter receptors, including alpha7-AChR, have been demonstrated on peripheral blood lymphocytes (PBL) and it has been suggested that these peripheral recepto...

journal_title：Neuropsychobiology

authors： Perl O,Strous RD,Dranikov A,Chen R,Fuchs S

更新日期：2006-01-01 00:00:00

abstract：:The focus is on evaluating the relationships between early behavioural problems and biochemical variables at adult age and their significance for early criminality and violent behaviour in a life perspective. In the present study, using prospective longitudinal data, a sample of males with a history of early criminal ...

journal_title：Neuropsychobiology

authors： Eklund J,Alm PO,af Klinteberg B

更新日期：2005-01-01 00:00:00

abstract：:Renal lithium clearance and the serum lithium levels following a single oral loading dose of lithium were used as measures to predict lithium dose requirement during long-term maintenance at 3 different psychiatric centers in North America. Saliva lithium values were also investigated at one of the centers. The correl...

journal_title：Neuropsychobiology

authors： Tyrer SP,Grof P,Kalvar M,Shopsin B

更新日期：1981-01-01 00:00:00

abstract：:Personality traits were assessed in a series of 148 patients classified according to Winokur into depression pure disease (DPD), depression spectrum disease (DSD) and sporadic depression (SD) with the addition of a fourth group: family history positive-others (FH + .O) comprised of patients with psychiatric disorders ...

journal_title：Neuropsychobiology

authors： Perris C,Eisemann M,Ericsson U,von Knorring L,Perris H

更新日期：1983-01-01 00:00:00

abstract：:Angiotensin-converting enzyme (ACE) is a key enzyme in the renin-angiotensin system and can modulate dopamine turnover in the midbrain. Previous studies have revealed changes in the central ACE levels for schizophrenic patients, possibly related to the polydipsia commonly demonstrated for chronic schizophrenia. An ins...

journal_title：Neuropsychobiology

authors： Ouyang WC,Wang YC,Hong CJ,Cheng CY,Tsai SJ

更新日期：2001-01-01 00:00:00

abstract：:The somnopolygraphs of 26 sober chronic alcoholics were compared with those of an age-matched control group, after approximately 25 days of sobriety. The sleep efficiency index and latency to sleep onset were significantly disturbed in alcoholic subjects. There was a decrease in the number of REM episodes. Slow-wave s...

journal_title：Neuropsychobiology

authors： Snyder S,Karacan I

更新日期：1985-01-01 00:00:00

abstract：:Single, 50- and 100-mg oral doses of phenobarbital and a matching placebo were administered double-blind to 8 young, healthy male subjects. Multilead electroencephalographic (EEG) samples were recorded prior to, and at regular intervals within the 2 h following administration. The EEG signal was processed by power spe...

journal_title：Neuropsychobiology

authors： Sannita WG,Balbi A,Giacchino F,Rosadini G

更新日期：1990-01-01 00:00:00

abstract：:Little information exists on the concentrations of recent antidepressants and their metabolites in cerebrospinal fluid (CSF). Using a stereoselective method, we measured plasma and CSF levels of mirtazapine (MIR), N-demethylmirtazapine and 8-OH-MIR in 3 depressed patients treated with racemic MIR (45 mg/day) for 4 wee...

journal_title：Neuropsychobiology

authors： Baumann P,Jonzier-Perey M,Paus E,Nikisch G

更新日期：2006-01-01 00:00:00

abstract：:Eight healthy paid male volunteers (age: 21-28 years, mean: 24.5 +/- 1.7 years; weight 62-79 kg) were administered via intravenous infusion (3 min) acute 25-, 50-, and 75-mg doses of phosphatidylserine, or matching placebo in a latin-square design. Multichannel EEG recordings were performed in baseline conditions, dur...

journal_title：Neuropsychobiology

authors： Rosadini G,Sannita WG,Nobili F,Cenacchi T

更新日期：1990-01-01 00:00:00

abstract：:Twenty-two female patients with anorexia nervosa, restricted type, 14-35 years old, were treated with a 4-month course of combined cognitive-behavioral therapy, nutritional counselling and antidepressant drugs (nortriptyline for 7, fluoxetine for 15). Patients were monitored for body mass index (BMI), for eating disor...

journal_title：Neuropsychobiology

authors： Brambilla F,Draisci A,Peirone A,Brunetta M

更新日期：1995-01-01 00:00:00

abstract：:In this study, we examined the effect of the 5-HT2A,C receptor agonist (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on locomotor activity and the head twitch response in rats by the repeated (twice daily for 4 days) subcutaneous administration of 0.9% saline (1 ml/kg) or (+/-)-3,4-Methylenedioxymethamphet...

journal_title：Neuropsychobiology

authors： Granoff MI,Ashby CR Jr

更新日期：1998-01-01 00:00:00

abstract：:Intermittent short-lived episodes of depression were examined in a group of 20 recurrent suicidal attempters without major depression, classified misleadingly as borderline personality disorders on DSM-IIIR, during careful prospective follow-up for between 4 and 6 months. The duration of depressions clustered tightly ...

journal_title：Neuropsychobiology

authors： Montgomery SA,Montgomery D,Baldwin D,Green M

更新日期：1989-01-01 00:00:00

abstract：:Plasma cortisol, catecholamine and cyclic AMP levels, response to dexamethasone suppression test and platelet MAO activity have been determined in 15 patients suffering from bipolar affective psychosis, each examined during a depressive, a manic and an euthymic phase, and in 15 sex- and age-matched normal controls. Me...

journal_title：Neuropsychobiology

authors： Maj M,Ariano MG,Arena F,Kemali D

更新日期：1984-01-01 00:00:00

abstract：:The responses of cortisol to acute administration of saline and of clonidine (2.5 micrograms/kg B.W.) were examined in 10 children and adolescents with major depressive disorder and in 10 age- and sex-matched controls. Clonidine administration did not inhibit cortisol secretion in controls or in patients, contrary to ...

journal_title：Neuropsychobiology

authors： Brambilla F,Guareschi-Cazzullo A,Musetti C,Nobile P,Tacchini C

更新日期：1993-01-01 00:00:00

abstract：:A potential candidate gene that could contribute to the education process is the apolipoprotein E (apo E) gene that has been shown to correlate with memory function and memory decline. We measured apo E polymorphism in groups of probands with different levels of education selected from a population sample. In the grou...

journal_title：Neuropsychobiology

authors： Hubacek JA,Pitha J,Skodová Z,Adámková V,Lánská V,Poledne R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:In depressed patients, overstimulation of the hypothalamo-pituitary-adrenocortical (HPA) system, probably caused by glucocorticoid receptor resistance, is the most consistent neurobiological finding. Glucocorticoids themselves are reported to increase leptin synthesis and secretion in humans. METHODS:We exa...

journal_title：Neuropsychobiology

authors： Himmerich H,Zimmermann P,Ising M,Kloiber S,Lucae S,Kunzel HE,Binder EB,Holsboer F,Uhr M

更新日期：2007-01-01 00:00:00

abstract：:In 63 depressed patients, the associations between severity of depression, psychomotor retardation, assessed by the Bech-Rafaelsen Melancholia Scale, and EEG spectral analysis were examined. Slow EEG activity (theta 2/alpha 1 bands) was positively and fast activity (alpha 3/beta bands) negatively correlated with the o...

journal_title：Neuropsychobiology

authors： Nieber D,Schlegel S

更新日期：1992-01-01 00:00:00

abstract：:The effects of zolpidem or zaleplon on sleep architecture, respiratory patterns and performance were assessed at a simulated altitude of 4,000 m. Twelve male healthy subjects spent 4 nights in a decompression chamber, 1 at sea level (baseline), 3 at 4,000 m to test zolpidem (10 mg), zaleplon (10 mg) and placebo, given...

journal_title：Neuropsychobiology

authors： Beaumont M,Batéjat D,Coste O,Van Beers P,Colas A,Clère JM,Piérard C

更新日期：2004-01-01 00:00:00