The effect of the repeated administration of the compound 3,4-methylenedioxymethamphetamine on the response of rats to the 5-HT2A,C receptor agonist (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI).

abstract：:We hypothesized that levels of N-acetyl-beta-glucosaminidase (NAG) would differ between patients making serious versus nonserious suicide attempts. The levels of NAG from 11 patients hospitalized for serious suicide attempts were compared to 5 patients whose suicide attempts were not rated serious. There was a signifi...

journal_title：Neuropsychobiology

authors： Garvey MJ,Underwood K

更新日期：2000-01-01 00:00:00

abstract：:Symptoms of anxiety suggest autonomic dysfunction and most of the psychotropic agents used to treat anxiety and affective disorders have strong autonomic effects. This article describes the utility and importance of analysis of heart rate and blood pressure time series to study cardiac autonomic function in psychiatri...

journal_title：Neuropsychobiology

authors： Yeragani VK

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Considerable evidence suggests that variation of the serotonin-transporter-linked promoter region (5- HTTLPR) is associated with anxiety-related traits. Academic outcomes are also more closely related to trait anxiety. This preliminary study aimed to explore the association between academic performance and l...

journal_title：Neuropsychobiology

authors： Calapoğlu M,Sahin-Calapoğlu N,Karaçöp A,Soyöz M,Elyıldırım UY,Avşaroğlu S

更新日期：2011-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled, multiple-ascending-dose study, the encephalotropic and psychotropic properties of ABIO-08/01, a new potentially anxiolytic and nootropic isoxazoline, were studied in 16 young healthy males. In a randomized nonbalanced phase 1 study, they received 3 oral drug doses (10, 20, 40 mg)...

journal_title：Neuropsychobiology

authors： Saletu-Zyhlarz GM,Anderer P,Wolzt M,Semlitsch HV,Assandri A,Nessi P,Nannipieri F,Rosini S,Saletu B

更新日期：2009-01-01 00:00:00

abstract：:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical import...

journal_title：Neuropsychobiology

authors： Refsum HE,Astrup C

更新日期：1980-01-01 00:00:00

abstract：:Cerebral impedance changes (F changes) indicating cerebral blood flow variations in the central and precentral areas were measured with a rheographic technique in normal subjects preparing for and carrying out a motor task. The time course of the F changes was studied and several significant correlations were establis...

journal_title：Neuropsychobiology

authors： Jacquy J,Piraux A,Jocquet P,Lhoas JP,Noel G

更新日期：1977-01-01 00:00:00

abstract：:The relation between EEG spectral power and alterations of the visual evoked potential (VEP) during different behavioral states and after intraperitoneal application of neuroactive drugs have been investigated in Long-Evans rats. FFT power and field potential maps were made in five behavioral states of the unrestraine...

journal_title：Neuropsychobiology

authors： Bringmann A,Klingberg F

更新日期：1995-01-01 00:00:00

abstract：:Isolation causes important changes in the behavioral reactivity of rats to environmental stimuli. These changes include deficit in sensorimotor gating and altered fear-like responses to aversive stimuli. Measures of ultrasound vocalizations at 20-22 kHz when rats are exposed to threatening conditions, such as novelty,...

journal_title：Neuropsychobiology

authors： Nunes Mamede Rosa ML,Nobre MJ,Ribeiro Oliveira A,Brandão ML

更新日期：2005-01-01 00:00:00

abstract：:In the search for differential mechanisms underlying clozapine's superior antipsychotic efficacy, the purinergic system has been considered, since an antagonist of the adenosine receptor A(2A) was shown to block clozapine acute effects on c-fos expression in rat striatum. Further investigating the interaction of cloza...

journal_title：Neuropsychobiology

authors： Lara DR,Vianna MR,de Paris F,Quevedo J,Oses JP,Battastini AM,Sarkis JJ,Souza DO

更新日期：2001-01-01 00:00:00

abstract：:In two studies experimentally induced colds slowed the speed of response in a serial reaction task. Responding was also slower during the incubation period of the illness, which shows that performance on such a task may be used to predict subsequent illness. Volunteers who had no significant clinical illness, but who ...

journal_title：Neuropsychobiology

authors： Smith AP,Tyrrell DA,Al-Nakib W,Coyle KB,Donovan CB,Higgins PG,Willman JS

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Patients with bipolar disorder are at a high risk for becoming obese. Adipokines are associated with depression and obesity via the inflammatory process. However, few studies have investigated the associations between depression and leptin, adiponectin and resistin levels in patients with bipolar disorder. W...

journal_title：Neuropsychobiology

authors： Lee HJ,Kim SH,Kim EY,Lee NY,Yu HY,Kim YS,Ahn YM

更新日期：2014-01-01 00:00:00

abstract：:Platelet 5-HT and plasma cortisol concentrations were determined in 59 schizophrenic patients with different time course of illness before and after dexamethasone suppression test (DST). An abnormal DST (nonsuppression) was observed in 51% of patients. In these patients basal cortisol and platelet 5-HT concentrations ...

journal_title：Neuropsychobiology

authors： Jakovljević M,Mück-Seler D,Pivac N,Crncević Z

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The failure to inhibit pleasurable but inappropriate urges is associated with frontal lobe pathology and has been suggested as a possible cause of pedophilic behavior. However, imaging and neuropsychological findings about frontal pathology in pedophilia are heterogeneous. In our study we therefore address i...

journal_title：Neuropsychobiology

authors： Habermeyer B,Esposito F,Händel N,Lemoine P,Kuhl HC,Klarhöfer M,Mager R,Mokros A,Dittmann V,Seifritz E,Graf M

更新日期：2013-01-01 00:00:00

abstract：:Several antipsychotics and antidepressants have been associated with electrocardiogram alterations, the most clinically relevant of which is the heart rate-corrected QT interval (QTc) prolongation, a risk factor for sudden cardiac death. Genetic variants influence drug-induced QTc prolongation and can provide valuable...

journal_title：Neuropsychobiology

authors： Corponi F,Fabbri C,Boriani G,Diemberger I,Albani D,Forloni G,Serretti A

更新日期：2019-01-01 00:00:00

abstract：:Quantitative assessment of regional cerebral blood flow (rCBF) was performed in a 22-year-old man with intractable temporal lobe epilepsy on long-term high-dose phenytoin (PHT) therapy, using single photon emission computed tomography (SPECT) with N-isopropyl-(iodine-123)-p-iodoamphetamine. In all the SPECT scans repe...

journal_title：Neuropsychobiology

authors： Jibiki I,Kido H,Yamaguchi N,Matsuda H,Hisada K

更新日期：1993-01-01 00:00:00

abstract：:Abnormal anterior pituitary responsiveness to acute administration of thyrotropin-releasing hormone was investigated in 8 patients, 6 women and 2 men, with primary affective disorders in a depressive phase and in 2 women with schizoaffective disorders. Thyrotropin-releasing hormone, 500 micrograms i.v., induced a rise...

journal_title：Neuropsychobiology

authors： Brambilla F,Scarone S,Massironi R,Nobile P,Pugnetti L

更新日期：1982-01-01 00:00:00

abstract：:The performance on spatial and nonspatial associative learning tasks was tested in a sample of male drug-free DSM III-diagnosed schizophrenic patients and in a closely matched normal control group. Schizophrenics showed a worse performance on both versions of the task, but especially on the nonspatial one. A significa...

journal_title：Neuropsychobiology

authors： Kemali D,Maj M,Galderisi S,Monteleone P,Mucci A

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that altered immune responses play a role in the pathogenesis of autism spectrum disorders (ASD), together with dysfunction of the serotonergic and glutamatergic systems. Since the kynurenine (KYN) pathway that degrades tryptophan (TRP) is activated in various neuroinflammatory s...

journal_title：Neuropsychobiology

authors： Bryn V,Verkerk R,Skjeldal OH,Saugstad OD,Ormstad H

更新日期：2017-01-01 00:00:00

abstract：:The effects of the addition of short-term lithium to long-term administration of antidepressants (clomipramine or citalopram) on the levels of 5-HT and 5-HIAA and serotonergic receptors were studied in the rat cortex. The addition of short-term Li to long-term antidepressant treatment potentiated an increase in 5-HIAA...

journal_title：Neuropsychobiology

authors： Okamoto Y,Motohasi N,Hayakawa H,Muraoka M,Yamawaki S

更新日期：1996-01-01 00:00:00

abstract：:Plasma cortisol, catecholamine and cyclic AMP levels, response to dexamethasone suppression test and platelet MAO activity have been determined in 15 patients suffering from bipolar affective psychosis, each examined during a depressive, a manic and an euthymic phase, and in 15 sex- and age-matched normal controls. Me...

journal_title：Neuropsychobiology

authors： Maj M,Ariano MG,Arena F,Kemali D

更新日期：1984-01-01 00:00:00

abstract：INTRODUCTION:Butyrate is a short-chain fatty acid metabolite produced by microbiota in the colon. With its antioxidant properties, butyrate has also been shown to alter the neurological functions in affective disorder models, suggesting it as a key mediator in gut-brain interactions. OBJECTIVE:Here, we evaluated the n...

journal_title：Neuropsychobiology

authors： Rode J,Yang L,König J,Hutchinson AN,Wall R,Venizelos N,Brummer RJ,Rangel I,Vumma R

更新日期：2020-10-19 00:00:00

abstract：:Behavioral abnormalities, jumping reaction, increase in spontaneous activity abnormal violence, and lethargy were observed in long-term ultraviolet A (UVA)-irradiated hairy male Crj:CD-1 mice. The learning ability of 6- and 12-months UVA-irradiated mice was significantly reduced compared to un-irradiated age-matched m...

journal_title：Neuropsychobiology

authors： Hiramoto K,Okada T,Ito M

更新日期：1996-01-01 00:00:00

abstract：:Hallucinogenic drug-induced states are considered as models for acute schizophrenic disorders (experimental psychoses). In a double-blind study with healthy volunteers we investigated the influence of the serotonergic hallucinogen psilocybin, the ecstasy-like drug 3,4-methylenedioxyethylamphetamine (MDE), the stimulan...

journal_title：Neuropsychobiology

authors： Gouzoulis-Mayfrank E,Thelen B,Maier S,Heekeren K,Kovar KA,Sass H,Spitzer M

更新日期：2002-01-01 00:00:00

abstract：AIMS:The aim was to measure the prefrontal cortical activity involved in shifting spatial attention to visual stimuli in the left or right visual field using near-infrared spectroscopy. METHODS:Eleven participants performed a simple vigilance task, an endogenous attention task and an exogenous attention task. In the e...

journal_title：Neuropsychobiology

authors： Takahashi M,Ikegami M

更新日期：2008-01-01 00:00:00

abstract：:Dopamine depletion induced by administration of Ro4-1284 produces a condition of rapid and repeated eye blinking in rats. This condition mimics the human disorder, blepharospasm, which often accompanies parkinsonism and other dopamine deficiency disorders. When given a 3-week course of a compound (SR-3) developed from...

journal_title：Neuropsychobiology

authors： Mostofsky DI,Yehuda S,Rabinovitz S,Carasso R

更新日期：2000-01-01 00:00:00

abstract：:The genotypes of the CYP2E1 loci of 35 alcoholic and 130 nonalcoholic (healthy controls) Japanese were investigated to determine the relationship between CYP2E1 (C/D) polymorphism and susceptibility to alcohol dependence. There was a significant (d.f. = 1, chi2 = 11.0, p < 0.001) difference in the CYP2E1 C gene freque...

journal_title：Neuropsychobiology

authors： Iwahashi K,Ameno S,Ameno K,Okada N,Kinoshita H,Sakae Y,Nakamura K,Watanabe M,Ijiri I,Harada S

更新日期：1998-11-01 00:00:00

abstract：:An auditory event-related potential paradigm was designed to objectively quantify the effects of drugs on the central nervous system (CNS). A series of tones was presented at three random interstimulus intervals (ISI). The amplitude of N1-P2 and the recovery of this complex across ISI appear to be rapid, reliable and ...

journal_title：Neuropsychobiology

authors： Noldy NE,Neiman J,el-Nesr B,Carlen PL

更新日期：1990-01-01 00:00:00

abstract：:Monoamine oxidase A (MAOA) is a mitochondrial enzyme involved in the degradation of dopamine, serotonin and norepinephrine and these neurotransmitters are hypothesized to be involved in the cognitive function of humans. This study of a cohort of 191 healthy young Chinese females attempts to utilize the intelligence qu...

journal_title：Neuropsychobiology

authors： Yu YW,Tsai SJ,Hong CJ,Chen MC,Yang CW,Chen TJ

更新日期：2005-01-01 00:00:00

abstract：:Recent studies have suggested that synaptic abnormalities may be part of the pathophysiology of schizophrenia. SNAP-25 (synaptosomal-associated protein of 25 kD) is one of the synaptic proteins responsible for presynaptic neurotransmission, axonal elongation and synaptogenesis. Genetic variation in the 5'-upstream reg...

journal_title：Neuropsychobiology

authors： Tachikawa H,Harada S,Kawanishi Y,Okubo T,Suzuki T

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Although differences in symptom profiles and outcome between depressive patients with an underlying major depressive disorder (MDD) and bipolar depression (BD) have been reported, studies with sequential short-interval assessments in a real-life inpatient setting are scarce. OBJECTIVES:To examine potential ...

journal_title：Neuropsychobiology

authors： Hebbrecht K,Stuivenga M,Birkenhäger T,van der Mast RC,Sabbe B,Giltay EJ

更新日期：2020-01-01 00:00:00