Relationship of N-acetyl-beta- glucosaminidase levels to seriousness of suicide attempts.

abstract：:As low-dose amphetamine stimulation of locomotor activity in the rat depends upon a mesolimbic dopaminergic substrate, neuroleptic antagonism of this behavior has been suggested as a model for studying antipsychotic activity. Animals in the present study received 21 days of chronic treatment with 1.0 mg/kg amphetamine...

journal_title：Neuropsychobiology

authors： Lynch MR,Kuhn HG,Carey RJ

更新日期：1988-01-01 00:00:00

abstract：:The effects of zolpidem or zaleplon on sleep architecture, respiratory patterns and performance were assessed at a simulated altitude of 4,000 m. Twelve male healthy subjects spent 4 nights in a decompression chamber, 1 at sea level (baseline), 3 at 4,000 m to test zolpidem (10 mg), zaleplon (10 mg) and placebo, given...

journal_title：Neuropsychobiology

authors： Beaumont M,Batéjat D,Coste O,Van Beers P,Colas A,Clère JM,Piérard C

更新日期：2004-01-01 00:00:00

abstract：:Evidence from preclinical studies, preliminary clinical reports, pharmacologic challenge studies and a small number of controlled trials suggests that several antiepileptic agents--valproate, carbamazepine, and clonazepam--may have therapeutic effects in the treatment of patients with panic disorder. We review the the...

journal_title：Neuropsychobiology

authors： Keck PE Jr,McElroy SL,Tugrul KC,Bennett JA,Smith JM

更新日期：1993-01-01 00:00:00

abstract：:The popular recreational drug, (+/-)3, 4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') is a potent and selective brain serotonin (5-HT) neurotoxin in animals. MDMA-induced 5-HT neurotoxicity can be demonstrated using a variety of neurochemical, neuroanatomical and, more recently, functional measures of 5-HT neurons....

journal_title：Neuropsychobiology

authors： Ricaurte GA,Yuan J,McCann UD

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND AIM:Repetitive transcranial magnetic stimulation (rTMS) is supposed to be not as effective in severe depression as it is in medium depression. We evaluated the treatment response to an ultra-high-frequency (UHF; 30 Hz) approach, which was used to maximize the rTMS efficacy in severely ill patients. METH...

journal_title：Neuropsychobiology

authors： Ullrich H,Kranaster L,Sigges E,Andrich J,Sartorius A

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:There is some evidence that repetitive transcranial magnetic stimulation (rTMS) is an effective method of treating patients suffering from obsessive-compulsive disorder (OCD). Here, we tested the hypothesis that rTMS has a positive impact both on symptom severity and cognitive performance in such patients. Sp...

journal_title：Neuropsychobiology

authors： Jahangard L,Haghighi M,Shyayganfard M,Ahmadpanah M,Sadeghi Bahmani D,Bajoghli H,Holsboer-Trachsler E,Brand S

更新日期：2016-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled study the effect of nocturnal traffic noise and bedtime medication of a new benzodiazepine, OX-373, on objective and subjective sleep variables as well as on the quality of morning awakenings was investigated. 10 healthy subjects spent 17 nights in the sleep laboratory: 2 adaptati...

journal_title：Neuropsychobiology

authors： Saletu B,Grünberger J

更新日期：1981-01-01 00:00:00

abstract：:The region coding human leukocyte antigen (HLA) on chromosome 6q21 was shown to be associated with both the vulnerability to schizophrenia and presence of eye movement disturbances (EMD). The aim of this preliminary study was to investigate how individual class I and II HLA antigens in schizophrenic patients may be re...

journal_title：Neuropsychobiology

authors： Bogacki PA,Borkowska A,Wojtanowska-Bogacka M,Rybakowski JK

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:A growing number of studies indicate increased impulsivity in patients with opioid dependence (OD). However, few studies exclude concomitant drug use and consider depression as a comorbidity, both of which can bias results. AIM:We aimed to compare impulsivity in patients with OD enrolled in maintenance thera...

journal_title：Neuropsychobiology

authors： Peters L,Soyka M

更新日期：2019-01-01 00:00:00

abstract：:Hallucinogenic drug-induced states are considered as models for acute schizophrenic disorders (experimental psychoses). In a double-blind study with healthy volunteers we investigated the influence of the serotonergic hallucinogen psilocybin, the ecstasy-like drug 3,4-methylenedioxyethylamphetamine (MDE), the stimulan...

journal_title：Neuropsychobiology

authors： Gouzoulis-Mayfrank E,Thelen B,Maier S,Heekeren K,Kovar KA,Sass H,Spitzer M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Psychosis spectrum disorders, especially schizophrenia, have been linked to disturbed dopaminergic activity in the brain. Plasma homovanillic acid (pHVA) levels partly represent dopaminergic metabolism in the central nervous system. In the present study associations between (changes in) pHVA levels, symptom ...

journal_title：Neuropsychobiology

authors： van de Kerkhof NW,Fekkes D,van der Heijden FM,Egger JI,Verhoeven WM

更新日期：2015-01-01 00:00:00

abstract：:Time trends and periodic cycles in REM sleep eye movements were examined in 6 functional and 6 mongoloid adolescent retardates. Both groups of subjects showed approximately equal percentages of linear trends, quadratic trends, linear and quadratic trends, and absence of trend. The eye movement time-series were subject...

journal_title：Neuropsychobiology

authors： Krynicki V

更新日期：1976-01-01 00:00:00

abstract：:Saliva cortisol was measured at 11 p.m. in a sample of 74 psychiatric inpatients composed of 24 primary endogenous depressives, 40 secondary depressives and 20 nondepressives (DSM III and Saint-Louis criteria). Primary depressives had significantly higher 11 p.m. saliva cortisol levels than nondepressives (p less than...

journal_title：Neuropsychobiology

authors： Guéchot J,Lépine JP,Cohen C,Fiet J,Lempérière T,Dreux C

更新日期：1987-01-01 00:00:00

abstract：:All-night sleep of 5 healthy male subjects was scored on the basis of EEG (paper records), EMG and EOG into the stages of wakefulness, REM sleep and slow sleep stages 1-4 according to Rechtschaffen and Kales. Spectral analysis for 8 EEG channels was then performed and spectral parameters (total power and coherence for...

journal_title：Neuropsychobiology

authors： Molinari L,Dumermuth G,Lange B

更新日期：1984-01-01 00:00:00

abstract：:Recent studies suggest that the eye blink response to intense acoustic stimuli consists of two components that may occasionally result in waveforms with two peaks. In the present study, the prevalence, peak latencies, and peak magnitudes in responses exhibiting one or two peaks were investigated in healthy subjects in...

journal_title：Neuropsychobiology

authors： Meincke U,Light GA,Geyer MA,Braff DL

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:Previous functional neuroimaging studies have reported that patients with schizophrenia show reduced prefrontal activation during cognitive tasks whereas patients with schizotypal personality disorder (SPD) show preserved or even increased right prefrontal activation, compared to healthy controls; on th...

journal_title：Neuropsychobiology

authors： Hori H,Nagamine M,Soshi T,Okabe S,Kim Y,Kunugi H

更新日期：2008-01-01 00:00:00

abstract：:The author contended opposite pharmacological effects resulting from lithium and amphetamine. Three groups, each one consisting of four rats, were put on chronic lithium condition to measure its effects on amphetamine hyperactivity. This condition was effected after appropriate handling and saline control periods and ...

journal_title：Neuropsychobiology

authors： Flemenbaum A

更新日期：1975-01-01 00:00:00

abstract：:Eight patients with chronic obsessive-compulsive neurosis were subjected to trazodone, an antidepressant acting on the serotonergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement ha...

journal_title：Neuropsychobiology

authors： Prasad A

更新日期：1986-01-01 00:00:00

abstract：:Little is known about the effects of cocaine on cognitive tasks. Event-related potentials (ERP) were recorded in 7 cocaine abusers during the performance of the auditory oddball task before and after the intravenous injections of saline and cocaine (60-80 mg). The P3B and slow wave components of the ERP were significa...

journal_title：Neuropsychobiology

authors： Herning RI,Glover BJ,Guo X

更新日期：1994-01-01 00:00:00

abstract：:Acute quantitative electroencephalographic effects of cigarette smoking were examined in 15 smokers within a repeated-measures design which assessed changes in power-spectral estimates following acute pre-treatment with placebo, a dose (20 mg) of mecamylamine, a dose (0.6 mg) of scopolamine and a combined dose of meca...

journal_title：Neuropsychobiology

authors： Knott VJ,Harr A,Ilivitsky V,Mahoney C

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Reaction time variability (RTV) is considered a valid endophenotype of attention deficit/hyperactivity disorder (ADHD). It is also often used to examine the efficacy of drug treatment or individual patients' treatment responses and has been furthermore suggested to significantly reduce the potential number o...

journal_title：Neuropsychobiology

authors： Grant P,Kuepper Y,Wielpuetz C,Hennig J

更新日期：2014-01-01 00:00:00

abstract：:Cardiovascular measurements were used as indicators of autonomic arousal during an orthostatic challenge test without medication and after a test dose of 150 mg perazine in 20 acute schizophrenic patients. Unmedicated schizophrenics showed elevated heart rates and elevated systolic and diastolic blood pressure in comp...

journal_title：Neuropsychobiology

authors： Volz HP,Mackert A,Diefenbacher A,Friedrich A,Gaebel W,Müller H,Stock G,Möller HJ

更新日期：1994-01-01 00:00:00

abstract：:Twenty-three chronic undifferentiated schizophrenics, 13 women and 10 men, aged 37-64 years with 15-to 40-year histories of the disease were given either thyrotropin-releasing hormone (TRH) (10 subjects) or DDAVP (13 subjects) with the aim to improve the negative symptoms of the disease and memory. TRH (600 micrograms...

journal_title：Neuropsychobiology

authors： Brambilla F,Aguglia E,Massironi R,Maggioni M,Grillo W,Castiglioni R,Catalano M,Drago F

更新日期：1986-01-01 00:00:00

abstract：:Tetrahydrobiopterin (BH(4)) is a vital cofactor maintaining availability of the amine neurotransmitters [dopamine (DA), noradrenaline (NA), and serotonin (5-HT)], regulating the synthesis of nitric oxide (NO) by nitric oxide synthase (NOS), and stimulating and modulating the glutamatergic system (directly and indirect...

journal_title：Neuropsychobiology

authors： Richardson MA,Read LL,Taylor Clelland CL,Reilly MA,Chao HM,Guynn RW,Suckow RF,Clelland JD

更新日期：2005-01-01 00:00:00

abstract：:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical import...

journal_title：Neuropsychobiology

authors： Refsum HE,Astrup C

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Although differences in symptom profiles and outcome between depressive patients with an underlying major depressive disorder (MDD) and bipolar depression (BD) have been reported, studies with sequential short-interval assessments in a real-life inpatient setting are scarce. OBJECTIVES:To examine potential ...

journal_title：Neuropsychobiology

authors： Hebbrecht K,Stuivenga M,Birkenhäger T,van der Mast RC,Sabbe B,Giltay EJ

更新日期：2020-01-01 00:00:00

abstract：:The aim of this paper was to determine whether the prolonged decrease in seizure threshold produced by chemical kindling was accompanied by behavioural changes in tests of anxiety and aggression. The responses of rats in five tests were examined after chronic treatment with the benzodiazepine inverse agonist FG7142. T...

journal_title：Neuropsychobiology

authors： Taylor SC,Johnston AL,Wilks LJ,Nicholass JM,File SE,Little HJ

更新日期：1988-01-01 00:00:00

abstract：:Supine and standing heart rate (HR) and blood pressure measures were compared among 19 nonsmoking normal controls, 29 smoking patients and 36 nonsmoking patients with panic disorder. The smoking patients had a significantly higher supine HR, standing diastolic blood pressure, standing mean blood pressure and supine an...

journal_title：Neuropsychobiology

authors： Yeragani VK,Pohl R,Balon R,Ramesh C,Glitz D,Sherwood P

更新日期：1990-01-01 00:00:00

abstract：:Marked hostility toward relatives, therapists and friends is very frequently observed in anorexia nervosa (AN) as expression of outward-directed aggressiveness which interferes with the therapeutic programs of the patients. With the purpose to investigate this aspect of the disorder and its biological background, we s...

journal_title：Neuropsychobiology

authors： Brambilla F,Bellodi L,Arancio C,Limonta D,Ferrari E,Solerte B

更新日期：2001-01-01 00:00:00

abstract：:Little information exists on the concentrations of recent antidepressants and their metabolites in cerebrospinal fluid (CSF). Using a stereoselective method, we measured plasma and CSF levels of mirtazapine (MIR), N-demethylmirtazapine and 8-OH-MIR in 3 depressed patients treated with racemic MIR (45 mg/day) for 4 wee...

journal_title：Neuropsychobiology

authors： Baumann P,Jonzier-Perey M,Paus E,Nikisch G

更新日期：2006-01-01 00:00:00