Abstract:
:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical importance to establish the clinical diagnosis of reactive depression because these states are different from endogenous depressions with regard to pathogenesis, prognosis and treatment.
journal_name
Neuropsychobiologyjournal_title
Neuropsychobiologyauthors
Refsum HE,Astrup Cdoi
10.1159/000117739subject
Has Abstractpub_date
1980-01-01 00:00:00pages
79-90issue
2eissn
0302-282Xissn
1423-0224journal_volume
6pub_type
杂志文章abstract::A double-blind comparison of zimeldine, a selective 5-HT reuptake inhibitor, and nomifensine, a noradrenaline and a dopamine reuptake inhibitor, was carried out in 43 inpatients with a scheduled treatment period of 6 weeks. All patients were diagnosed as definite major depressive disorder according to Research Diagnos...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章
doi:10.1159/000118086
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:Schizophrenia is a genetically complex disorder with an unknown pathophysiology. Several genes implicated in glutamate metabolism have been associated with the disorder. Recent studies of polymorphisms in the dystrobrevin-binding protein 1 gene (DTNBP1; dysbindin) and D-amino-acid-oxidase (DAO) gene, both in...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000235799
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The availability of tobacco products is associated with the likelihood that adolescents will begin using tobacco. Yet the relationship between nicotine availability and voluntary consumption has not been tested experimentally in developing rats. METHOD:The impact of environmental availability on adolescent ...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000103905
更新日期:2007-01-01 00:00:00
abstract::The antidepressive and anxiolytic efficacy of flupenthixol has been investigated in numerous controlled and open trials involving patients with endogenous, reactive as well as senile depressions. When administered at a mean daily single or multiple dose of 1-2 mg, flupenthixol proved to be a very effective and well-to...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000117999
更新日期:1983-01-01 00:00:00
abstract::The serotonergic system has been implicated in the production of the N1 and P2 components of auditory evoked potentials (AEPs). Moreover, studies have indicated the influence of heritability in the genesis of these AEP components. The serotonin transporter is the major site of serotonin reuptake into the presynaptic n...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章
doi:10.1159/000065412
更新日期:2002-01-01 00:00:00
abstract::Two preliminary studies have indicated a variation in season of birth in severely language-disordered children. In the current study, the season of birth in 472 Danish children with language disorder born between 1958 and 1976 was compared with the season of birth of all Danish live-born children in the same period. F...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000084166
更新日期:2005-01-01 00:00:00
abstract::Eight patients with chronic obsessive-compulsive neurosis were subjected to trazodone, an antidepressant acting on the serotonergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement ha...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118274
更新日期:1986-01-01 00:00:00
abstract::We report 3 patients who experienced nonconvulsive status epilepticus following generalized convulsions during antidepressant treatment. All showed prolonged confusion with some psychiatric symptoms, and their electroencephalograms (EEGs) showed either bilateral synchronous multiple spike wave discharges or continuous...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000119397
更新日期:1997-01-01 00:00:00
abstract::During the last few years, the working group 'Psychophysiology' of the Association for Methodology and Documentation in Psychiatry (AMDP) discussed the possibility of the establishment of defined EEG modules in psychiatry. It was the aim to create a common data pool in order to be able to have access to larger data se...
journal_title:Neuropsychobiology
pub_type: 指南,杂志文章
doi:10.1159/000119370
更新日期:1997-01-01 00:00:00
abstract::The relationship between physical activity and mental health has been widely investigated, and several hypotheses have been formulated about it. Specifically, during the aging process, physical exercise might represent a potential adjunctive treatment for neuropsychiatric disorders and cognitive impairment, helping de...
journal_title:Neuropsychobiology
pub_type: 杂志文章,评审
doi:10.1159/000223730
更新日期:2009-01-01 00:00:00
abstract::Urinary 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in 53 depressed women were compared to current suicidal thoughts or activity. Comparisons were also made between MHPG and past suicide attempts, number of past attempts, and seriousness of the worst attempt. There was a weak trend for current but not past suicidali...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000119072
更新日期:1994-01-01 00:00:00
abstract::A sample of schizophrenic inpatients and a control sample of normal volunteers, matched for age and sex were tested on two tasks before and after an exposure condition in which they pointed repeatedly to a target while viewing their hands and the target through prisms. Both groups showed significant changes in both ta...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000117753
更新日期:1980-01-01 00:00:00
abstract::The effects of zolpidem or zaleplon on sleep architecture, respiratory patterns and performance were assessed at a simulated altitude of 4,000 m. Twelve male healthy subjects spent 4 nights in a decompression chamber, 1 at sea level (baseline), 3 at 4,000 m to test zolpidem (10 mg), zaleplon (10 mg) and placebo, given...
journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000076723
更新日期:2004-01-01 00:00:00
abstract::In the search for differential mechanisms underlying clozapine's superior antipsychotic efficacy, the purinergic system has been considered, since an antagonist of the adenosine receptor A(2A) was shown to block clozapine acute effects on c-fos expression in rat striatum. Further investigating the interaction of cloza...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000054925
更新日期:2001-01-01 00:00:00
abstract::The new anticonvulsant, lamotrigine, is becoming an important tool in the treatment of bipolar disorder, including bipolar depression. Its efficacy in bipolar depression might be linked to its inhibition of serotonin uptake. We present the case of a female schizoaffective patient successfully treated with 400 mg of la...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000026538
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:This study aimed to compare the effects of aerobic training (AT), strength training (ST) and low-intensity exercise in a control group (CG) as adjunct treatments to pharmacotherapy for major depressive disorder (MDD) in older persons. METHODS:Older persons clinically diagnosed with MDD (n = 27) and treated ...
journal_title:Neuropsychobiology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000503750
更新日期:2020-01-01 00:00:00
abstract::In the present study, single-unit extracellular recording was used in male Wistar rats to compare the effects of a single dose (acute treatment) and a 21-day regimen (long-term treatment) with clomipramine (2.5 mg/kg) and fluoxetine (1.0 mg/kg) on the spontaneous firing rate of nucleus accumbens (NAcc) neurons connect...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000073627
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND/AIMS:In general, humans tend to discount the value of delayed reward. An increase in the rate of discounting leads to an inability to select a delayed reward over a smaller immediate reward (reward-delay impulsivity). Although deficits in the serotonergic system are implicated in this reward-delay impulsivit...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000328990
更新日期:2012-01-01 00:00:00
abstract::Substance P (SP) is a neuropeptide which is abundant in the periphery and the central nervous system, where it is colocalized with other neurotransmitters such as serotonin or dopamine. SP has been proposed to play a role in the regulation of pain including migraine and fibromyalgia, asthma, inflammatory bowel disease...
journal_title:Neuropsychobiology
pub_type: 杂志文章,评审
doi:10.1159/000049254
更新日期:2002-01-01 00:00:00
abstract::Individuals differ in hypnotizability. Information on hypnotizability-related EEG characteristics is controversial and incomplete, particularly on intracerebral source localization and EEG dimensionality. 19-channel, eyes-closed resting EEGs from right-handed, healthy, 8 high- and 4 low-hynotizable subjects (age: 26.7...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000054942
更新日期:2001-01-01 00:00:00
abstract::The region coding human leukocyte antigen (HLA) on chromosome 6q21 was shown to be associated with both the vulnerability to schizophrenia and presence of eye movement disturbances (EMD). The aim of this preliminary study was to investigate how individual class I and II HLA antigens in schizophrenic patients may be re...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000085595
更新日期:2005-01-01 00:00:00
abstract::Nitric oxide (NO) has been implicated to play a role in the pathogenesis of depressive disorders. Adrenomedullin (AM) induces vasorelaxation by activating adenylate cyclase and also by stimulating the release of NO. AM immune reactivity is present in the brain, consistent with a role as neurotransmitter. Therefore, it...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000048677
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The 5-hydroxytryptamine (5-HT) neurotransmitter system and lateral habenula (LHb) are involved in the regulation of depression, while the mechanisms remain to be clarified. OBJECTIVES:The effects and possible mecha-nism underlying activation or blockade of 5-HT4 receptors (5-HT4Rs) in the LHb in depression ...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000508680
更新日期:2020-07-14 00:00:00
abstract::Ten closed head-injured patients and 10 matched control subjects participated in a study that examined quantitated EEG data during cognitive task performance. The head-injured patients performed significantly worse than controls on all four tasks and had significantly higher EEG amplitudes and amplitude variances. A d...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118471
更新日期:1988-01-01 00:00:00
abstract::Volunteers who develop a cold following virus challenge were significantly slower on choice reaction time tasks than those with no illness. This effect was still observed after the clinical symptoms had gone. In contrast to this, influenza illnesses only impaired performance in tasks in which subjects were uncertain w...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000118558
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:We examined striatal dopamine transporter (DAT) binding in bipolar and unipolar depressed patients and compared these values to those obtained from healthy control subjects using the selective DAT radioligand [(99m)Tc]TRODAT-1 and single photon emission computed tomography imaging. We hypothesized that DAT le...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000106476
更新日期:2007-01-01 00:00:00
abstract::This paper reports a replication study of a four-group cluster-analytic typology of depressed patients. Several hierarchial agglomerative clustering procedures were applied on the original patient sample using a slightly reduced variable pool. The best replication obtained used Ward's error sum of squares method and w...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000117595
更新日期:1977-01-01 00:00:00
abstract::The concentrations of adenosine 3'5'-cyclic monophosphate (cyclic AMP) in cerebrospinal fluid (CSF) in manic-melancholic patients were studied. As control groups served patients suffering from other psychiatric disorders as well as neruological and orthopedic patients. The results showed no difference between the vari...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000117548
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:We have investigated the efficacy of high-frequency left (HFL) versus low-frequency right (LFR) repetitive transcranial magnetic stimulation (rTMS) in depression, focusing on specific symptoms as possible predictors of outcome for these two different types of stimulation. METHOD:Seventy-four outpatients wit...
journal_title:Neuropsychobiology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000315439
更新日期:2010-01-01 00:00:00
abstract::Dysfunctional mechanisms in the serotonergic system have been implicated in suicidal behavior among patients with schizophrenia. However, previous association analyses of major serotonin genes have provided inconsistent findings regarding their role in suicidal behavior. The goal of the current study was to identify s...
journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000441191
更新日期:2016-01-01 00:00:00