Female genital disorder as adverse symptom of lamotrigine treatment. A serotoninergic effect?

Abstract:

:The new anticonvulsant, lamotrigine, is becoming an important tool in the treatment of bipolar disorder, including bipolar depression. Its efficacy in bipolar depression might be linked to its inhibition of serotonin uptake. We present the case of a female schizoaffective patient successfully treated with 400 mg of lamotrigine developing considerable genital disorder, a side effect well known from the treatment with selective serotonin reuptake inhibitors (SSRIs). We suggest that female genital disorder induced by high doses of lamotrigine is a serotoninergic side effect.

journal_name

Neuropsychobiology

journal_title

Neuropsychobiology

authors

Erfurth A,Amann B,Grunze H

doi

10.1159/000026538

subject

Has Abstract

pub_date

1998-10-01 00:00:00

pages

200-1

issue

3

eissn

0302-282X

issn

1423-0224

pii

nps38200

journal_volume

38

pub_type

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