Spontaneous and drug-induced locomotor activity after partial dopamine denervation of the ventral striatum.

abstract：:The relationship between physical activity and mental health has been widely investigated, and several hypotheses have been formulated about it. Specifically, during the aging process, physical exercise might represent a potential adjunctive treatment for neuropsychiatric disorders and cognitive impairment, helping de...

journal_title：Neuropsychobiology

authors： Deslandes A,Moraes H,Ferreira C,Veiga H,Silveira H,Mouta R,Pompeu FA,Coutinho ES,Laks J

更新日期：2009-01-01 00:00:00

abstract：:The search for specific predepressive personality factors has a long tradition in psychiatry. Studies in which assessments were made prospectively, before the onset of a first-ever episode of the illness, are, however, rare. In the present report from the Lundby Study we have investigated premorbid, mainly personality...

journal_title：Neuropsychobiology

authors： Rorsman B,Gräsbeck A,Hagnell O,Isberg PE,Otterbeck L

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Stress is a precipitating factor for both binge eating and bulimia nervosa (BN); however, the biological mechanisms through which it may trigger binge eating are poorly understood. There is evidence that the adrenal hormone cortisol and the gastric peptide ghrelin might be involved in stress-induced food ing...

journal_title：Neuropsychobiology

authors： Monteleone P,Tortorella A,Scognamiglio P,Serino I,Monteleone AM,Maj M

更新日期：2012-01-01 00:00:00

abstract：:The region coding human leukocyte antigen (HLA) on chromosome 6q21 was shown to be associated with both the vulnerability to schizophrenia and presence of eye movement disturbances (EMD). The aim of this preliminary study was to investigate how individual class I and II HLA antigens in schizophrenic patients may be re...

journal_title：Neuropsychobiology

authors： Bogacki PA,Borkowska A,Wojtanowska-Bogacka M,Rybakowski JK

更新日期：2005-01-01 00:00:00

abstract：:Premenstrual tension was studied in 16 females, using both biochemical and psychological parameters during the pre- and postmenstrual phases. Uptake of serotonin (5-HT) and the levels of 5-HT in platelet-rich plasma and platelet-poor plasmas were determined. Degrees of distress experienced pre- and postmenstrually wer...

journal_title：Neuropsychobiology

authors： Taylor DL,Mathew RJ,Ho BT,Weinman ML

更新日期：1984-01-01 00:00:00

abstract：:Serotonergic dysfunction is implicated in Alzheimer's disease (AD) on the basis of studies of serotonin and its metabolite in postmortem specimens and CSF. There were also reports on association of a tryptophan hydroxylase (TPH) intron 7 variant and CSF 5-hydroxyindoleacetic acid concentrations. These suggested TPH mi...

journal_title：Neuropsychobiology

authors： Wang YC,Tsai SJ,Liu TY,Liu HC,Hong CJ

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:There is some evidence that repetitive transcranial magnetic stimulation (rTMS) is an effective method of treating patients suffering from obsessive-compulsive disorder (OCD). Here, we tested the hypothesis that rTMS has a positive impact both on symptom severity and cognitive performance in such patients. Sp...

journal_title：Neuropsychobiology

authors： Jahangard L,Haghighi M,Shyayganfard M,Ahmadpanah M,Sadeghi Bahmani D,Bajoghli H,Holsboer-Trachsler E,Brand S

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:A growing number of studies indicate increased impulsivity in patients with opioid dependence (OD). However, few studies exclude concomitant drug use and consider depression as a comorbidity, both of which can bias results. AIM:We aimed to compare impulsivity in patients with OD enrolled in maintenance thera...

journal_title：Neuropsychobiology

authors： Peters L,Soyka M

更新日期：2019-01-01 00:00:00

abstract：:Twenty-two female patients with anorexia nervosa, restricted type, 14-35 years old, were treated with a 4-month course of combined cognitive-behavioral therapy, nutritional counselling and antidepressant drugs (nortriptyline for 7, fluoxetine for 15). Patients were monitored for body mass index (BMI), for eating disor...

journal_title：Neuropsychobiology

authors： Brambilla F,Draisci A,Peirone A,Brunetta M

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Panic disorder (PD) is a common and often chronic psychiatric condition that can lead to considerable disability in daily life. Using [(18)F]fluorodeoxyglucose-PET, we examined brain baseline glucose metabolism in PD patients in comparison with normal controls and the changes in glucose metabolism after 12 w...

journal_title：Neuropsychobiology

authors： Kang EH,Park JE,Lee KH,Cho YS,Kim JJ,Yu BH

更新日期：2012-01-01 00:00:00

abstract：:Neural-network pattern classifiers were used to study the effects of long half-life flurazepam (30 mg) and quazepam (15 mg), and short half-life triazolam (0.5 mg) on non-REM sleep. We measured the magnitude of effect, time course, and EEG spectral signature of the three benzodiazepines as a function of third-of-night...

journal_title：Neuropsychobiology

authors： Gevins AS,Stone RK,Ragsdale SD

更新日期：1988-01-01 00:00:00

abstract：:In humans and several other mammals, a quantitative EEG analysis has been used to study the regulation of sleep-wake behavior. In all mammalian species studied, cortical EEG recorded during non-REM sleep (NREMS) is characterized by the occurrence of spindles and high voltage, slow waves (0.5-4.0 Hz). Furthermore, slow...

journal_title：Neuropsychobiology

authors： Lancel M

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP), a marker of underlying low-grade inflammation, has been associated with the pathophysiology of bipolar disorder. Additionally, bipolar disorder may be accompanied by functional or structural cerebral alterations. We attempted to discover whether serum high-sensitivity CRP (hs-CRP) le...

journal_title：Neuropsychobiology

authors： Chung KH,Huang SH,Wu JY,Chen PH,Hsu JL,Tsai SY

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Memory processes, as reflected by 'old/new' effects of event-related potentials (ERPs), have been shown to be impaired in depressed patients. This variability might be partly explained by biological factors. S100B is a glial calcium-binding protein with neuroplastic properties; S100B serum levels have been sh...

journal_title：Neuropsychobiology

authors： Zhang Y,Rothermundt M,Peters M,Wiesmann M,Hoy L,Arolt V,Emrich HM,Dietrich DE

更新日期：2009-01-01 00:00:00

abstract：:Recent studies have suggested that synaptic abnormalities may be part of the pathophysiology of schizophrenia. SNAP-25 (synaptosomal-associated protein of 25 kD) is one of the synaptic proteins responsible for presynaptic neurotransmission, axonal elongation and synaptogenesis. Genetic variation in the 5'-upstream reg...

journal_title：Neuropsychobiology

authors： Tachikawa H,Harada S,Kawanishi Y,Okubo T,Suzuki T

更新日期：2001-01-01 00:00:00

abstract：:This report presents the results of a retrospective analysis of pooled efficacy data from eight studies in which buspirone was compared to placebo in 520 patients with generalized anxiety disorder (GAD). In addition to evaluating overall efficacy in the composite patient data base, four criteria were used to identify ...

journal_title：Neuropsychobiology

authors： Gammans RE,Stringfellow JC,Hvizdos AJ,Seidehamel RJ,Cohn JB,Wilcox CS,Fabre LF,Pecknold JC,Smith WT,Rickels K

更新日期：1992-01-01 00:00:00

abstract：:The responses of cortisol to acute administration of saline and of clonidine (2.5 micrograms/kg B.W.) were examined in 10 children and adolescents with major depressive disorder and in 10 age- and sex-matched controls. Clonidine administration did not inhibit cortisol secretion in controls or in patients, contrary to ...

journal_title：Neuropsychobiology

authors： Brambilla F,Guareschi-Cazzullo A,Musetti C,Nobile P,Tacchini C

更新日期：1993-01-01 00:00:00

abstract：:The usual method for extracting evoked potentials from EEG, the so-called averaging, is based on the hypothesis of the stationarity of the single responses in every EEG segment. Therefore, the possible variability of the single responses cannot be regarded. In this paper, a method for estimating single evoked response...

journal_title：Neuropsychobiology

authors： Heinze HJ,Künkel H

更新日期：1984-01-01 00:00:00

abstract：:Cortisol has a modulatory influence on cognitive functions in humans. Both impairing and enhancing effects of cortisol administration have been shown for hippocampus-dependent declarative memory, and impairing effects have been shown for prefrontal-cortex-dependent working memory function. Given the high density of gl...

journal_title：Neuropsychobiology

authors： Kumsta R,Entringer S,Koper JW,van Rossum EF,Hellhammer DH,Wüst S

更新日期：2010-01-01 00:00:00

abstract：:Previously, we performed an MRI study that revealed smaller volumes of the subregions of the cerebellar vermis in men and women with chronic schizophrenia. An issue that arose from that study was whether similar structural changes in the cerebellum are found in patients with first-episode schizophrenia. In the present...

journal_title：Neuropsychobiology

authors： Okugawa G,Nobuhara K,Takase K,Kinoshita T

更新日期：2007-01-01 00:00:00

abstract：:We agree with the conclusions of a recent article in this journal [James, Neuropsychobiology 1994;30:124-125] that studies on the psychoactive effects of caffeine need to take into account the possibility that the results obtained might represent merely the reversal of deleterious effects of caffeine deprivation rathe...

journal_title：Neuropsychobiology

authors： Rogers PJ,Richardson NJ,Dernoncourt C

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Derangements of the gut microbiome have been linked to increased systemic inflammation and central nervous system disorders, including schizophrenia. This systematic review thus aimed to investigate the hypothesis that probiotic supplementation improves schizophrenia symptoms. METHODS:By using the keywords ...

journal_title：Neuropsychobiology

authors： Ng QX,Soh AYS,Venkatanarayanan N,Ho CYX,Lim DY,Yeo WS

更新日期：2019-01-01 00:00:00

abstract：:Eight patients with chronic obsessive-compulsive neurosis were subjected to trazodone, an antidepressant acting on the serotonergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement ha...

journal_title：Neuropsychobiology

authors： Prasad A

更新日期：1986-01-01 00:00:00

abstract：:A common polymorphism in the alpha1-antichymotrypsin (ACT) gene is associated with Alzheimer's disease. ACT is also a trophic factor in the hippocampal neurons. In order to examine if the ACT gene plays a role in the pathogenesis of schizophrenic disorders, patients (n = 175) and control subjects (n = 114) were genoty...

journal_title：Neuropsychobiology

authors： Chiu HJ,Hong CJ,Chen JY,Wang YC,Lin CY,Bai YM,Song HL,Lai HC,Tsai SJ

更新日期：1999-01-01 00:00:00

abstract：:A group of 27 patients with definite (n = 20) or probable (n = 7) RDC major depressive disorder underwent 2 sleep EEGs and 1 TRH test while in a drug-free depressive phase. A short mean REM latency (less than 60 min) identified 55.5% of major depressives while added use of blunted TSH responses (delta max. less than 5...

journal_title：Neuropsychobiology

authors： Pugnetti L,Scarone S,Brambilla F

更新日期：1987-01-01 00:00:00

abstract：:Evidence from preclinical studies, preliminary clinical reports, pharmacologic challenge studies and a small number of controlled trials suggests that several antiepileptic agents--valproate, carbamazepine, and clonazepam--may have therapeutic effects in the treatment of patients with panic disorder. We review the the...

journal_title：Neuropsychobiology

authors： Keck PE Jr,McElroy SL,Tugrul KC,Bennett JA,Smith JM

更新日期：1993-01-01 00:00:00

abstract：:Suicide is a major problem for psychiatry. Depression is the most common mental disorder related to suicidal behavior. The present study aimed at investigating the relationship between the symptomatology related to death, dying, and suicide and neurobiological factors in depressed patients. Fifty patients aged 21-60 y...

journal_title：Neuropsychobiology

authors： Fountoulakis KN,Iacovides A,Fotiou F,Nimatoudis J,Bascialla F,Ioannidou C,Kaprinis G,Bech P

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Patients with bulimia nervosa (BN) are reported to have decreased postprandial levels of cholecystokinin (CCK) and peptide YY (PYY). Fatty nutrients are the most powerful stimulus for releasing these peptides. Cholestyramine is an anion exchanger which adsorbs bile salts and reduces the digestion of lipids, a...

journal_title：Neuropsychobiology

authors： Rigamonti AE,Sartorio A,Scognamiglio P,Bini S,Monteleone AM,Mastromo D,Marazzi N,Cella SG,Monteleone P

更新日期：2014-01-01 00:00:00

abstract：:Neurobiological and pharmacological research has suggested that dysregulation of the central noradrenergic systems might be involved in the pathophysiology of attention deficit hyperactivity disorder (ADHD). Previous studies have demonstrated that the norepinephrine transporter gene (SLC6A2) is associated with ADHD. T...

journal_title：Neuropsychobiology

authors： Cho SC,Kim JW,Kim BN,Hwang JW,Park M,Kim SA,Cho DY,Yoo HJ,Chung US,Son JW,Park TW

更新日期：2008-01-01 00:00:00

abstract：:Fifteen general practitioners treated 21 newly diagnosed insomniac patients with benzodiazepines. In 15 cases, a short-acting benzodiazepine was prescribed without regard to the type, severity, duration and probable cause of insomnia. Sleep-wake ambulatory recordings were made at the respective homes of the patients b...

journal_title：Neuropsychobiology

authors： Wauquier A,Declerck A

更新日期：1990-01-01 00:00:00