Evidence for an association between polymorphism in the serotonin-2A receptor variant (102T/C) and increment of N100 amplitude in schizophrenics treated with clozapine.

abstract：:Changes of field potentials electrically evoked from the mesencephalon were studied in two dopaminergic target areas. The modulation of the responses in prefrontal cortex and striatum induced by intravenous injection of various compounds influencing central dopaminergic transmission is followed. In general, drugs with...

journal_title：Neuropsychobiology

authors： Dimpfel W

更新日期：1985-01-01 00:00:00

abstract：:Failure to gain weight during withdrawal from chronic regimens of dependence-producing drugs is observed in laboratory rats. Withdrawal from the benzodiazepine anxiolytic agent diazepam, whether induced by cessation of treatment or precipitated by administration of the specific benzodiazepine antagonist Ro-15,1788, is...

journal_title：Neuropsychobiology

authors： Eison MS

更新日期：1986-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled study the effect of nocturnal traffic noise and bedtime medication of a new benzodiazepine, OX-373, on objective and subjective sleep variables as well as on the quality of morning awakenings was investigated. 10 healthy subjects spent 17 nights in the sleep laboratory: 2 adaptati...

journal_title：Neuropsychobiology

authors： Saletu B,Grünberger J

更新日期：1981-01-01 00:00:00

abstract：:In this study, we examined the effect of the 5-HT2A,C receptor agonist (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on locomotor activity and the head twitch response in rats by the repeated (twice daily for 4 days) subcutaneous administration of 0.9% saline (1 ml/kg) or (+/-)-3,4-Methylenedioxymethamphet...

journal_title：Neuropsychobiology

authors： Granoff MI,Ashby CR Jr

更新日期：1998-01-01 00:00:00

abstract：:The prevalence of 3,4-methylenedioxymethamphetamine (MDMA) use has increased globally and the pattern of consumption has changed considerably. Previously, a subculture of MDMA users was fairly restricted to the dance club scene. More recently, use has spread outside of this subculture and now many users consume MDMA f...

journal_title：Neuropsychobiology

authors： Schenk S

更新日期：2009-01-01 00:00:00

abstract：:Six WHO Collaborating Centre took part in the study of the antithymic activity of blood sera of patients suffering from schizophrenia. Blood serum specimens from 118 schizophrenic patients and 62 mentally healthy donors were investigated. Statistically significant differences between schizophrenic patients and the con...

journal_title：Neuropsychobiology

authors： Koliaskina G,Tsutsulkovskaya M,Domashneva I,Maznina T,Kielholz P,Gastpar M,Bunney W,Rafaelsen O,Heltberg J,Coppen A,Hippius H,Hoecherl B,Vartanian F

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND AIM:Repetitive transcranial magnetic stimulation (rTMS) is supposed to be not as effective in severe depression as it is in medium depression. We evaluated the treatment response to an ultra-high-frequency (UHF; 30 Hz) approach, which was used to maximize the rTMS efficacy in severely ill patients. METH...

journal_title：Neuropsychobiology

authors： Ullrich H,Kranaster L,Sigges E,Andrich J,Sartorius A

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:eLORETA (exact low-resolution brain electromagnetic tomography) is a technique created by Pascual-Marqui et al. [Int J Psychophysiol. 1994 Oct; 18(1): 49-65] for the 3-dimensional representation of current source density in the brain by electroencephalography (EEG) data. Kurtosis analysis allows for the iden...

journal_title：Neuropsychobiology

authors： Ikeda S,Ishii R,Pascual-Marqui RD,Canuet L,Yoshimura M,Nishida K,Kitaura Y,Katsura K,Kinoshita T

更新日期：2019-01-01 00:00:00

abstract：:Regular repetition of one monitor of sensory perception and another of psychomotor perception revealed similar frequency and amplitude aspects of spontaneous endogenous free-running cycles of perception and others of vigilance. The ultradian periodicities of these cycles distinguish between persons with intact nervous...

journal_title：Neuropsychobiology

authors： Lovett Doust JW,Podnieks I

更新日期：1975-01-01 00:00:00

abstract：:We hypothesized that levels of N-acetyl-beta-glucosaminidase (NAG) would differ between patients making serious versus nonserious suicide attempts. The levels of NAG from 11 patients hospitalized for serious suicide attempts were compared to 5 patients whose suicide attempts were not rated serious. There was a signifi...

journal_title：Neuropsychobiology

authors： Garvey MJ,Underwood K

更新日期：2000-01-01 00:00:00

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for many neurotransmitter receptors. Among the adverse effects of clozapine, urinary incontinence is commonly found and is suggested to be caused by alpha-adrenergic blockade. We tested the hypothesis that clozapine-induced urinary incontinence is...

journal_title：Neuropsychobiology

authors： Hsu JW,Wang YC,Lin CC,Bai YM,Chen JY,Chiu HJ,Tsai SJ,Hong CJ

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:Corticotropin-releasing factor (CRF) plays a prominent role in mediating the effect of stressors on the hypothalamic-pituitary-adrenal axis. In this study, we examined the effects of chronic administration of second-generation antipsychotic drug ziprasidone on CRF mRNA expression in the hypothalamic paravent...

journal_title：Neuropsychobiology

authors： Park SW,Choi SM,Lee JG,Lee CH,Lee SJ,Kim NR,Kim YH

更新日期：2011-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled, multiple-ascending-dose study, the encephalotropic and psychotropic properties of ABIO-08/01, a new potentially anxiolytic and nootropic isoxazoline, were studied in 16 young healthy males. In a randomized nonbalanced phase 1 study, they received 3 oral drug doses (10, 20, 40 mg)...

journal_title：Neuropsychobiology

authors： Saletu-Zyhlarz GM,Anderer P,Wolzt M,Semlitsch HV,Assandri A,Nessi P,Nannipieri F,Rosini S,Saletu B

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The 5-hydroxytryptamine (5-HT) neurotransmitter system and lateral habenula (LHb) are involved in the regulation of depression, while the mechanisms remain to be clarified. OBJECTIVES:The effects and possible mecha-nism underlying activation or blockade of 5-HT4 receptors (5-HT4Rs) in the LHb in depression ...

journal_title：Neuropsychobiology

authors： Guo Y,Zhang L,Zhang J,Lv SX,Du CX,Wang T,Wang HS,Xie W,Liu J

更新日期：2020-07-14 00:00:00

abstract：:The relationships between sensation seeking, curiosity about sex, and total and free testosterone in inmates were investigated. The role of other hormones such as luteinizing hormone (LH), follicle-stimulating hormone (FSH), and sex hormone-binding globulin (SHBG) in these relationships was also analyzed. Previous ana...

journal_title：Neuropsychobiology

authors： Aluja A,García LF

更新日期：2005-01-01 00:00:00

abstract：:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical import...

journal_title：Neuropsychobiology

authors： Refsum HE,Astrup C

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:The failure to inhibit pleasurable but inappropriate urges is associated with frontal lobe pathology and has been suggested as a possible cause of pedophilic behavior. However, imaging and neuropsychological findings about frontal pathology in pedophilia are heterogeneous. In our study we therefore address i...

journal_title：Neuropsychobiology

authors： Habermeyer B,Esposito F,Händel N,Lemoine P,Kuhl HC,Klarhöfer M,Mager R,Mokros A,Dittmann V,Seifritz E,Graf M

更新日期：2013-01-01 00:00:00

abstract：:Cerebral impedance changes (F changes) indicating cerebral blood flow variations in the central and precentral areas were measured with a rheographic technique in normal subjects preparing for and carrying out a motor task. The time course of the F changes was studied and several significant correlations were establis...

journal_title：Neuropsychobiology

authors： Jacquy J,Piraux A,Jocquet P,Lhoas JP,Noel G

更新日期：1977-01-01 00:00:00

abstract：:Based on 5-HT hypothesis, L-5-HTP (150 or 300 mg/day) was given orally to 18 depressed patients. The global estimates were 2 very much improved; 8 much improved; 3 minimally improved, and 5 unchanged. The action of L-5-HTP was usually rapid. The elevation of the serum 5-HT level 1 week after L-5-HTP administration was...

journal_title：Neuropsychobiology

authors： Kaneko M,Kumashiro H,Takahashi Y,Hoshino Y

更新日期：1979-01-01 00:00:00

abstract：:Clinical observations have suggested that lithium may exert adverse effects on memory. The difficulty in achieving empirical consensus regarding this issue has reflected several methodological problems: diversity of research designs, heterogeneous samples, lack of control groups and the possible confounding of memory ...

journal_title：Neuropsychobiology

authors： Engelsmann F,Ghadirian AM,Grof P

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Self-immolation (SI) is considered one of the most painful, dramatic, and at the same time most inexplicable methods of suicide, with a high social impact. Prevalence rates are particularly high in Iran, and in north-western Iran specifically. Here, we report sociodemographic, psychological, and psychiatric ...

journal_title：Neuropsychobiology

authors： Ahmadpanah M,Rahighi AH,Haghighi M

更新日期：2017-01-01 00:00:00

abstract：:As low-dose amphetamine stimulation of locomotor activity in the rat depends upon a mesolimbic dopaminergic substrate, neuroleptic antagonism of this behavior has been suggested as a model for studying antipsychotic activity. Animals in the present study received 21 days of chronic treatment with 1.0 mg/kg amphetamine...

journal_title：Neuropsychobiology

authors： Lynch MR,Kuhn HG,Carey RJ

更新日期：1988-01-01 00:00:00

abstract：:This study was conducted to elucidate the effects of electroconvulsive therapy (ECT) on frontal white matter in late-life depressed patients. Diffusion tensor imaging was performed on 8 late-life depressed patients and 12 healthy age-matched controls. The patients were scanned before and after a course of ECT. Fractio...

journal_title：Neuropsychobiology

authors： Nobuhara K,Okugawa G,Minami T,Takase K,Yoshida T,Yagyu T,Tajika A,Sugimoto T,Tamagaki C,Ikeda K,Sawada S,Kinoshita T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Abnormalities in different parameters of the norepinephrine system have been widely described in major depression. The presence of alpha(2)-adrenoreceptors in blood platelets, similar to those in the brain, prompted us to evaluate them in depressed patients, as compared with healthy controls. METHODS:Fiftee...

journal_title：Neuropsychobiology

authors： Marazziti D,Baroni S,Masala I,Di Nasso E,Giannaccini G,Betti L,Lucacchini A,Cassano GB

更新日期：2001-01-01 00:00:00

abstract：:The cerebrospinal fluid (CSF) concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) as well as their ratios and correlations were analyzed in relation to the season of birth. The sample consisted of 241 drug-free patients par...

journal_title：Neuropsychobiology

authors： Chotai J,Asberg M

更新日期：1999-01-01 00:00:00

abstract：:Neurobiological and pharmacological research has suggested that dysregulation of the central noradrenergic systems might be involved in the pathophysiology of attention deficit hyperactivity disorder (ADHD). Previous studies have demonstrated that the norepinephrine transporter gene (SLC6A2) is associated with ADHD. T...

journal_title：Neuropsychobiology

authors： Cho SC,Kim JW,Kim BN,Hwang JW,Park M,Kim SA,Cho DY,Yoo HJ,Chung US,Son JW,Park TW

更新日期：2008-01-01 00:00:00

abstract：:The somnopolygraphs of 26 sober chronic alcoholics were compared with those of an age-matched control group, after approximately 25 days of sobriety. The sleep efficiency index and latency to sleep onset were significantly disturbed in alcoholic subjects. There was a decrease in the number of REM episodes. Slow-wave s...

journal_title：Neuropsychobiology

authors： Snyder S,Karacan I

更新日期：1985-01-01 00:00:00

abstract：:Symptoms of anxiety suggest autonomic dysfunction and most of the psychotropic agents used to treat anxiety and affective disorders have strong autonomic effects. This article describes the utility and importance of analysis of heart rate and blood pressure time series to study cardiac autonomic function in psychiatri...

journal_title：Neuropsychobiology

authors： Yeragani VK

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:Patients with bulimia nervosa (BN) are reported to have decreased postprandial levels of cholecystokinin (CCK) and peptide YY (PYY). Fatty nutrients are the most powerful stimulus for releasing these peptides. Cholestyramine is an anion exchanger which adsorbs bile salts and reduces the digestion of lipids, a...

journal_title：Neuropsychobiology

authors： Rigamonti AE,Sartorio A,Scognamiglio P,Bini S,Monteleone AM,Mastromo D,Marazzi N,Cella SG,Monteleone P

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Due to its pharmacological properties, opipramol may be useful in the context of evening premedication in anaesthesiology. This trial examines whether quality of sleep the night prior to surgery can be improved by opipramol and whether this effect is dose dependent. A second objective of this study is to exam...

journal_title：Neuropsychobiology

authors： Hueppe M,Hartge D,Stoll KD,Ros A,Schmucker P,Gerlach K

更新日期：2011-01-01 00:00:00