Anterior cingulate abnormality as a neural correlate of mismatch negativity in schizophrenia.

abstract：BACKGROUND/AIMS:Neurotrophins such as brain-derived neurotrophic factor (BDNF) are vital for neuronal survival and adaptive plasticity. With high BDNF gene expression in the prefrontal cortex, BDNF is a potential regulatory factor for building and maintaining cognitive reserves. Recent studies suggest that individual d...

journal_title：Neuropsychobiology

authors： Koven NS,Collins LR

更新日期：2014-01-01 00:00:00

abstract：:Gamma-aminobutyric acid-B (GABAB) binding sites labelled with [3H]GABA were determined in postmortem frontal cortex samples of 20 control subjects and 16 suicides. The suicide group was further subdivided according to the method of suicide and the existence of depressive symptoms prior to death. No significant differe...

journal_title：Neuropsychobiology

authors： Arranz B,Cowburn R,Eriksson A,Vestling M,Marcusson J

更新日期：1992-01-01 00:00:00

abstract：:The brain activity of 13 right-handed students (6 men and 7 women) was determined using high resolution (99m)Tc-HMPAO brain SPECT images during visuospatial tasks. The results showed that there was no significant gender-specific difference in solving the visuospatial tasks and that no meaningful statistical difference...

journal_title：Neuropsychobiology

authors： Unterrainer J,Wranek U,Staffen W,Gruber T,Ladurner G

更新日期：2000-01-01 00:00:00

abstract：:The possible involvement of anxiety and learning/memory processes in escape-directed (struggling) behavior in a two-trial swimming test was investigated in mice, as well as the differential effects that low doses of flumazenil (a benzodiazepine receptor antagonist) could display depending on the animals' anxiety level...

journal_title：Neuropsychobiology

authors： Ferré P,Fernández Teruel A,Escorihuela RM,García E,Zapata A,Tobeña A

更新日期：1994-01-01 00:00:00

abstract：:Neurobiological and pharmacological research has suggested that dysregulation of the central noradrenergic systems might be involved in the pathophysiology of attention deficit hyperactivity disorder (ADHD). Previous studies have demonstrated that the norepinephrine transporter gene (SLC6A2) is associated with ADHD. T...

journal_title：Neuropsychobiology

authors： Cho SC,Kim JW,Kim BN,Hwang JW,Park M,Kim SA,Cho DY,Yoo HJ,Chung US,Son JW,Park TW

更新日期：2008-01-01 00:00:00

abstract：:In this study, we examined the effect of the 5-HT2A,C receptor agonist (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on locomotor activity and the head twitch response in rats by the repeated (twice daily for 4 days) subcutaneous administration of 0.9% saline (1 ml/kg) or (+/-)-3,4-Methylenedioxymethamphet...

journal_title：Neuropsychobiology

authors： Granoff MI,Ashby CR Jr

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:We have investigated the efficacy of high-frequency left (HFL) versus low-frequency right (LFR) repetitive transcranial magnetic stimulation (rTMS) in depression, focusing on specific symptoms as possible predictors of outcome for these two different types of stimulation. METHOD:Seventy-four outpatients wit...

journal_title：Neuropsychobiology

authors： Rossini D,Lucca A,Magri L,Malaguti A,Smeraldi E,Colombo C,Zanardi R

更新日期：2010-01-01 00:00:00

abstract：:Gamma oscillations (>30 Hz) in the brain are involved in attention, perception and memory. They are altered in various pathological states, as well as by neuropharmaceuticals, so that they are of interest in drug and clinical investigations. However, when the human electroencephalogram is recorded on the scalp, this n...

journal_title：Neuropsychobiology

authors： Nottage JF,Horder J

更新日期：2015-01-01 00:00:00

abstract：:Plasma levels of free and conjugated 3,4-dihydroxyphenylethyleneglycol (DOPEG), the main deaminated metabolite of norepinephrine, were assayed in 48 depressed patients before initiating a treatment with either maprotiline, an inhibitor of norepinephrine reuptake, or indalpine, a specific inhibitor of serotonin reuptak...

journal_title：Neuropsychobiology

authors： Lôo H,Benkelfat C,Poirier MF,Vanelle JM,Olié JP,Dennis T,Scatton B

更新日期：1986-01-01 00:00:00

abstract：:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical import...

journal_title：Neuropsychobiology

authors： Refsum HE,Astrup C

更新日期：1980-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled, multiple-ascending-dose study, the encephalotropic and psychotropic properties of ABIO-08/01, a new potentially anxiolytic and nootropic isoxazoline, were studied in 16 young healthy males. In a randomized nonbalanced phase 1 study, they received 3 oral drug doses (10, 20, 40 mg)...

journal_title：Neuropsychobiology

authors： Saletu-Zyhlarz GM,Anderer P,Wolzt M,Semlitsch HV,Assandri A,Nessi P,Nannipieri F,Rosini S,Saletu B

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:A growing number of studies indicate increased impulsivity in patients with opioid dependence (OD). However, few studies exclude concomitant drug use and consider depression as a comorbidity, both of which can bias results. AIM:We aimed to compare impulsivity in patients with OD enrolled in maintenance thera...

journal_title：Neuropsychobiology

authors： Peters L,Soyka M

更新日期：2019-01-01 00:00:00

abstract：:46 severely depressed inpatients received 10-hour intravenous infusions supplying a dose of 720 mg dibenzepin daily on 2 or some cases 3 successive days. The patients were kept under close psychiatric surveillance and their cardiovascular function was carefully monitored. The shorter infusions were as effective as inf...

journal_title：Neuropsychobiology

authors： Gastpar M,Cornu F,Faessler J,Haefliger A,Keller H,von Lerber W,Pagan J,Rem J

更新日期：1984-01-01 00:00:00

abstract：:Eight healthy paid male volunteers (age: 21-28 years, mean: 24.5 +/- 1.7 years; weight 62-79 kg) were administered via intravenous infusion (3 min) acute 25-, 50-, and 75-mg doses of phosphatidylserine, or matching placebo in a latin-square design. Multichannel EEG recordings were performed in baseline conditions, dur...

journal_title：Neuropsychobiology

authors： Rosadini G,Sannita WG,Nobili F,Cenacchi T

更新日期：1990-01-01 00:00:00

abstract：:The somnopolygraphs of 26 sober chronic alcoholics were compared with those of an age-matched control group, after approximately 25 days of sobriety. The sleep efficiency index and latency to sleep onset were significantly disturbed in alcoholic subjects. There was a decrease in the number of REM episodes. Slow-wave s...

journal_title：Neuropsychobiology

authors： Snyder S,Karacan I

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Eugen Bleuler, in his book Dementia praecox oder Gruppe der Schizophrenien, discussed issues of social psychiatry, and he considered complex interventions pivotal in the care for people with schizophrenia. Bleuler emphasised the potential of therapeutic communities in providing care, the drawbacks of extende...

journal_title：Neuropsychobiology

authors： Becker T,Kösters M

更新日期：2012-01-01 00:00:00

abstract：:The genotypes of the CYP2E1 loci of 35 alcoholic and 130 nonalcoholic (healthy controls) Japanese were investigated to determine the relationship between CYP2E1 (C/D) polymorphism and susceptibility to alcohol dependence. There was a significant (d.f. = 1, chi2 = 11.0, p < 0.001) difference in the CYP2E1 C gene freque...

journal_title：Neuropsychobiology

authors： Iwahashi K,Ameno S,Ameno K,Okada N,Kinoshita H,Sakae Y,Nakamura K,Watanabe M,Ijiri I,Harada S

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:This study aimed to compare the effects of aerobic training (AT), strength training (ST) and low-intensity exercise in a control group (CG) as adjunct treatments to pharmacotherapy for major depressive disorder (MDD) in older persons. METHODS:Older persons clinically diagnosed with MDD (n = 27) and treated ...

journal_title：Neuropsychobiology

authors： Moraes HS,Silveira HS,Oliveira NA,Matta Mello Portugal E,Araújo NB,Vasques PE,Bergland A,Santos TM,Engedal K,Coutinho ES,Schuch FB,Laks J,Deslandes AC

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Derangements of the gut microbiome have been linked to increased systemic inflammation and central nervous system disorders, including schizophrenia. This systematic review thus aimed to investigate the hypothesis that probiotic supplementation improves schizophrenia symptoms. METHODS:By using the keywords ...

journal_title：Neuropsychobiology

authors： Ng QX,Soh AYS,Venkatanarayanan N,Ho CYX,Lim DY,Yeo WS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Women have twice the rate of depression and anxiety disorders as men. Some studies suggest that this could be caused by women's greater sensitivity to negative emotions. Few brain imaging studies have compared the brain activity of men to women during a presentation of emotional stimuli. Our objective was to...

journal_title：Neuropsychobiology

authors： Thomas M,Gaudeau-Bosma C,Bouaziz N,Schenin-King Andrianisaina P,Benadhira R,Januel D,Moulier V

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Memory processes, as reflected by 'old/new' effects of event-related potentials (ERPs), have been shown to be impaired in depressed patients. This variability might be partly explained by biological factors. S100B is a glial calcium-binding protein with neuroplastic properties; S100B serum levels have been sh...

journal_title：Neuropsychobiology

authors： Zhang Y,Rothermundt M,Peters M,Wiesmann M,Hoy L,Arolt V,Emrich HM,Dietrich DE

更新日期：2009-01-01 00:00:00

abstract：:Evidence from preclinical studies, preliminary clinical reports, pharmacologic challenge studies and a small number of controlled trials suggests that several antiepileptic agents--valproate, carbamazepine, and clonazepam--may have therapeutic effects in the treatment of patients with panic disorder. We review the the...

journal_title：Neuropsychobiology

authors： Keck PE Jr,McElroy SL,Tugrul KC,Bennett JA,Smith JM

更新日期：1993-01-01 00:00:00

abstract：:This study investigated the acute effect of a dose range of low-to-moderate binge-like methamphetamine treatments on the regional expression of neurotrophin proteins in the brain and serum 2 h after the last dose, in addition to assessing the behavioural effects and dopamine neurotransmitter changes produced. Male Spr...

journal_title：Neuropsychobiology

authors： Moreira da Silva Santos A,Kelly JP,Doyle KM

更新日期：2017-01-01 00:00:00

abstract：:The prevalence of an abnormal response to the 1 mg dexamethasone suppression test (DST) was examined in 40 inpatients suffering from a major depressive disorder (MDD), 17 inpatients suffering from schizophrenia, and 30 normal controls. 23.5% of the schizophrenics were DST nonsuppressors compared to 52.5% of MDD patien...

journal_title：Neuropsychobiology

authors： Asnis GM,Eisenberg J,Lemus CZ,Halbreich U

更新日期：1986-01-01 00:00:00

abstract：:To clarify the circadian aspects of delayed sleep phase syndrome (DSPS) in 4 patients with DSPS, we recorded polysomnograms and rectal temperature before and after chronotherapy. The time interval (2.7 h) between sleep onset and rectal temperature minimum before chronotherapy was shorter than the time interval after c...

journal_title：Neuropsychobiology

authors： Ozaki N,Iwata T,Itoh A,Kogawa S,Ohta T,Okada T,Kasahara Y

更新日期：1988-01-01 00:00:00

abstract：:Using event-related potentials (ERPs), a reduction in the auditory N100, N200 and P300 amplitude has been found in schizophrenic patients and may represent some pathophysiological deficit. Therefore, we investigated whether the genetic variant of the serotonin-2A receptor is associated with ERP change after clozapine ...

journal_title：Neuropsychobiology

authors： Yu YW,Tsai SJ,Yang KH,Lin CH,Chen MC,Hong CJ

更新日期：2001-01-01 00:00:00

abstract：:This study was aimed to test the association between schizophrenia and a functional serotonin polymorphism (5-HTTLPR) in the upstream regulatory region. Genomic DNA analysis with polymerase chain reaction was used for 5-HTTLPR genotyping. One hundred and eleven patients with schizophrenia and 208 healthy individuals p...

journal_title：Neuropsychobiology

authors： Pae CU,Kim JJ,Lee SJ,Lee CU,Lee C,Paik IH,Park HR,Yang S,Serretti A

更新日期：2003-01-01 00:00:00

abstract：:The cerebrospinal fluid (CSF) concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) as well as their ratios and correlations were analyzed in relation to the season of birth. The sample consisted of 241 drug-free patients par...

journal_title：Neuropsychobiology

authors： Chotai J,Asberg M

更新日期：1999-01-01 00:00:00

abstract：:Fengabine is a new GABAmimetic compound active in animal models predictive of antidepressant activity. The present overview reports the results of 6 double-blind trials versus tricyclics (TCAs) (3 in outpatients and 3 in inpatients). Overall, 398 adult patients (149 males and 249 females) were treated; 194 with fengab...

journal_title：Neuropsychobiology

authors： Magni G,Garreau M,Orofiamma B,Palminteri R

更新日期：1989-01-01 00:00:00

abstract：:The medical histories of 600 psychotic and 369 nonpsychotic subjects were examined for the occurrence of rheumatic chorea. There was significantly more rheumatic chorea in the histories of psychotic patients than in nonpsychotics (p less than 0.01, chi-square). Neuropathological associations are discussed. ...

journal_title：Neuropsychobiology

authors： Wilcox JA,Nasrallah HA

更新日期：1986-01-01 00:00:00