Sixty years of lithium responders.

abstract：:Dopamine depletion induced by administration of Ro4-1284 produces a condition of rapid and repeated eye blinking in rats. This condition mimics the human disorder, blepharospasm, which often accompanies parkinsonism and other dopamine deficiency disorders. When given a 3-week course of a compound (SR-3) developed from...

journal_title：Neuropsychobiology

authors： Mostofsky DI,Yehuda S,Rabinovitz S,Carasso R

更新日期：2000-01-01 00:00:00

abstract：:The search for specific predepressive personality factors has a long tradition in psychiatry. Studies in which assessments were made prospectively, before the onset of a first-ever episode of the illness, are, however, rare. In the present report from the Lundby Study we have investigated premorbid, mainly personality...

journal_title：Neuropsychobiology

authors： Rorsman B,Gräsbeck A,Hagnell O,Isberg PE,Otterbeck L

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Time of onset of antipsychotic action is still a debated matter. We aimed to replicate and extend previous findings that early response can predict subsequent non-response. METHODS:86 acutely psychotic patients treated with haloperidol were studied. RESULTS:A PANSS reduction ≤16% at 1 week predict...

journal_title：Neuropsychobiology

authors： Giegling I,Porcelli S,Balzarro B,Andrisano C,Schäfer M,Möller HJ,Rujescu D,Serretti A

更新日期：2012-01-01 00:00:00

abstract：:Changes of field potentials electrically evoked from the mesencephalon were studied in two dopaminergic target areas. The modulation of the responses in prefrontal cortex and striatum induced by intravenous injection of various compounds influencing central dopaminergic transmission is followed. In general, drugs with...

journal_title：Neuropsychobiology

authors： Dimpfel W

更新日期：1985-01-01 00:00:00

abstract：:This study investigated the acute effect of a dose range of low-to-moderate binge-like methamphetamine treatments on the regional expression of neurotrophin proteins in the brain and serum 2 h after the last dose, in addition to assessing the behavioural effects and dopamine neurotransmitter changes produced. Male Spr...

journal_title：Neuropsychobiology

authors： Moreira da Silva Santos A,Kelly JP,Doyle KM

更新日期：2017-01-01 00:00:00

abstract：:Analysis of the mechanisms underlying the clinical effects of different drugs is a vital part of psychopharmacology. It is fair to say, however, that such analyses have thus far met with little success. This lack of success can be traced to a variety of sources that have flawed the analytical process itself. Detailed ...

journal_title：Neuropsychobiology

authors： Carlton PL

更新日期：1984-01-01 00:00:00

abstract：:Saliva cortisol was measured at 11 p.m. in a sample of 74 psychiatric inpatients composed of 24 primary endogenous depressives, 40 secondary depressives and 20 nondepressives (DSM III and Saint-Louis criteria). Primary depressives had significantly higher 11 p.m. saliva cortisol levels than nondepressives (p less than...

journal_title：Neuropsychobiology

authors： Guéchot J,Lépine JP,Cohen C,Fiet J,Lempérière T,Dreux C

更新日期：1987-01-01 00:00:00

abstract：:In the present study, the effects of short-acting benzodiazepines on nocturnal sleep and the carryover effects of these drugs were studied. The study involved 10 young, healthy male subjects who had given their written informed consent to participate. Either a placebo (PLA), 0.125 mg triazolam (TRZ), 0.25 mg TRZ or 0....

journal_title：Neuropsychobiology

authors： Suzuki H,Yamadera H,Asayama K,Kudo Y,Ito T,Tamura Y,Endo S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:Previous functional neuroimaging studies have reported that patients with schizophrenia show reduced prefrontal activation during cognitive tasks whereas patients with schizotypal personality disorder (SPD) show preserved or even increased right prefrontal activation, compared to healthy controls; on th...

journal_title：Neuropsychobiology

authors： Hori H,Nagamine M,Soshi T,Okabe S,Kim Y,Kunugi H

更新日期：2008-01-01 00:00:00

abstract：:Acute quantitative electroencephalographic effects of cigarette smoking were examined in 15 smokers within a repeated-measures design which assessed changes in power-spectral estimates following acute pre-treatment with placebo, a dose (20 mg) of mecamylamine, a dose (0.6 mg) of scopolamine and a combined dose of meca...

journal_title：Neuropsychobiology

authors： Knott VJ,Harr A,Ilivitsky V,Mahoney C

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The present study investigated the effects of rapid tryptophan depletion (RTD), and the ensuing reduction of central nervous system levels of serotonin (5-HT), upon reactive aggression in patients with attention deficit/hyperactivity disorder (ADHD). Furthermore, it was asked whether the relation between 5-H...

journal_title：Neuropsychobiology

authors： Stadler C,Zepf FD,Demisch L,Schmitt M,Landgraf M,Poustka F

更新日期：2007-01-01 00:00:00

abstract：:Supine and standing heart rate (HR) and blood pressure measures were compared among 19 nonsmoking normal controls, 29 smoking patients and 36 nonsmoking patients with panic disorder. The smoking patients had a significantly higher supine HR, standing diastolic blood pressure, standing mean blood pressure and supine an...

journal_title：Neuropsychobiology

authors： Yeragani VK,Pohl R,Balon R,Ramesh C,Glitz D,Sherwood P

更新日期：1990-01-01 00:00:00

abstract：:Hallucinogenic drug-induced states are considered as models for acute schizophrenic disorders (experimental psychoses). In a double-blind study with healthy volunteers we investigated the influence of the serotonergic hallucinogen psilocybin, the ecstasy-like drug 3,4-methylenedioxyethylamphetamine (MDE), the stimulan...

journal_title：Neuropsychobiology

authors： Gouzoulis-Mayfrank E,Thelen B,Maier S,Heekeren K,Kovar KA,Sass H,Spitzer M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Reaction time variability (RTV) is considered a valid endophenotype of attention deficit/hyperactivity disorder (ADHD). It is also often used to examine the efficacy of drug treatment or individual patients' treatment responses and has been furthermore suggested to significantly reduce the potential number o...

journal_title：Neuropsychobiology

authors： Grant P,Kuepper Y,Wielpuetz C,Hennig J

更新日期：2014-01-01 00:00:00

abstract：:As low-dose amphetamine stimulation of locomotor activity in the rat depends upon a mesolimbic dopaminergic substrate, neuroleptic antagonism of this behavior has been suggested as a model for studying antipsychotic activity. Animals in the present study received 21 days of chronic treatment with 1.0 mg/kg amphetamine...

journal_title：Neuropsychobiology

authors： Lynch MR,Kuhn HG,Carey RJ

更新日期：1988-01-01 00:00:00

abstract：:Twenty-seven medicated chronic schizophrenic female patients were tested for right or left turning behavior. No substantial right or left asymmetry was found, nor did the addition of the indirect dopaminergic agonist amantadine influence these results. Previous studies demonstrated left circling preference in chronic ...

journal_title：Neuropsychobiology

authors： Levine J,Martine T,Feraro R,Kimhi R,Bracha HS

更新日期：1997-01-01 00:00:00

abstract：:The effects of two benzodiazepines (alprazolam and bromazepam) on performance and event-related brain potentials (ERPs) in visual search and verbal recognition memory paradigms were tested in a placebo-controlled double-blind paradigm employing 12 young healthy subjects. Both drugs exerted similar effects on performan...

journal_title：Neuropsychobiology

authors： Münte TF,Gehde E,Johannes S,Seewald M,Heinze HJ

更新日期：1996-01-01 00:00:00

abstract：:The genotypes of the CYP2E1 loci of 35 alcoholic and 130 nonalcoholic (healthy controls) Japanese were investigated to determine the relationship between CYP2E1 (C/D) polymorphism and susceptibility to alcohol dependence. There was a significant (d.f. = 1, chi2 = 11.0, p < 0.001) difference in the CYP2E1 C gene freque...

journal_title：Neuropsychobiology

authors： Iwahashi K,Ameno S,Ameno K,Okada N,Kinoshita H,Sakae Y,Nakamura K,Watanabe M,Ijiri I,Harada S

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Considerable evidence suggests that variation of the serotonin-transporter-linked promoter region (5- HTTLPR) is associated with anxiety-related traits. Academic outcomes are also more closely related to trait anxiety. This preliminary study aimed to explore the association between academic performance and l...

journal_title：Neuropsychobiology

authors： Calapoğlu M,Sahin-Calapoğlu N,Karaçöp A,Soyöz M,Elyıldırım UY,Avşaroğlu S

更新日期：2011-01-01 00:00:00

abstract：:Human personality traits, which are substantially heritable, may be modulated by monoamine neurotransmitters. It has been demonstrated that the catechol-O-methyltransferase (COMT) Val158Met genetic polymorphism, a functional polymorphism that may affect monoamine metabolism, is possibly associated with specific person...

journal_title：Neuropsychobiology

authors： Tsai SJ,Hong CJ,Yu YW,Chen TJ

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The rs1344706 single nucleotide polymorphism in the ZNF804A gene is a common variant with strong evidence for association with schizophrenia. Recent studies show an association of rs1344706 with cognitive functioning, and there is some evidence suggesting that the risk allele may increase susceptibility for ...

journal_title：Neuropsychobiology

authors： Van Den Bossche MJ,Docx L,Morrens M,Cammaerts S,Strazisar M,Bervoets C,Smolders S,Depreeuw V,Lenaerts AS,De Rijk P,Del-Favero J,Sabbe BG

更新日期：2012-01-01 00:00:00

abstract：:Failure to gain weight during withdrawal from chronic regimens of dependence-producing drugs is observed in laboratory rats. Withdrawal from the benzodiazepine anxiolytic agent diazepam, whether induced by cessation of treatment or precipitated by administration of the specific benzodiazepine antagonist Ro-15,1788, is...

journal_title：Neuropsychobiology

authors： Eison MS

更新日期：1986-01-01 00:00:00

abstract：:The International Pharmaco-EEG Society (IPEG) presents updated guidelines summarising the requirements for the recording and computerised evaluation of pharmaco-EEG data in man. Since the publication of the first pharmaco-EEG guidelines in 1982, technical and data processing methods have advanced steadily, thus enhanc...

journal_title：Neuropsychobiology

authors： Jobert M,Wilson FJ,Ruigt GS,Brunovsky M,Prichep LS,Drinkenburg WH,IPEG Pharmaco-EEG Guidelines Committee.

更新日期：2012-01-01 00:00:00

abstract：:This report presents the results of a retrospective analysis of pooled efficacy data from eight studies in which buspirone was compared to placebo in 520 patients with generalized anxiety disorder (GAD). In addition to evaluating overall efficacy in the composite patient data base, four criteria were used to identify ...

journal_title：Neuropsychobiology

authors： Gammans RE,Stringfellow JC,Hvizdos AJ,Seidehamel RJ,Cohn JB,Wilcox CS,Fabre LF,Pecknold JC,Smith WT,Rickels K

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:Corticotropin-releasing factor (CRF) plays a prominent role in mediating the effect of stressors on the hypothalamic-pituitary-adrenal axis. In this study, we examined the effects of chronic administration of second-generation antipsychotic drug ziprasidone on CRF mRNA expression in the hypothalamic paravent...

journal_title：Neuropsychobiology

authors： Park SW,Choi SM,Lee JG,Lee CH,Lee SJ,Kim NR,Kim YH

更新日期：2011-01-01 00:00:00

abstract：:This study was aimed to test the association between schizophrenia and a functional serotonin polymorphism (5-HTTLPR) in the upstream regulatory region. Genomic DNA analysis with polymerase chain reaction was used for 5-HTTLPR genotyping. One hundred and eleven patients with schizophrenia and 208 healthy individuals p...

journal_title：Neuropsychobiology

authors： Pae CU,Kim JJ,Lee SJ,Lee CU,Lee C,Paik IH,Park HR,Yang S,Serretti A

更新日期：2003-01-01 00:00:00

abstract：:We agree with the conclusions of a recent article in this journal [James, Neuropsychobiology 1994;30:124-125] that studies on the psychoactive effects of caffeine need to take into account the possibility that the results obtained might represent merely the reversal of deleterious effects of caffeine deprivation rathe...

journal_title：Neuropsychobiology

authors： Rogers PJ,Richardson NJ,Dernoncourt C

更新日期：1995-01-01 00:00:00

abstract：:The lithium RBC/plasma ratio was determined in 59 patients during prophylactic lithium therapy -- 10 cycloid psychotics, 28 unipolars and 21 bipolars -- as well as in 20 patients during lithium therapy in phase of illness -- 8 cycloid psychotics, 5 unipolars and 7 bipolars. The lithium ratio was found to be normally d...

journal_title：Neuropsychobiology

authors： von Knorring L,Oreland L,Perris C,Runeberg S

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:Due to its pharmacological properties, opipramol may be useful in the context of evening premedication in anaesthesiology. This trial examines whether quality of sleep the night prior to surgery can be improved by opipramol and whether this effect is dose dependent. A second objective of this study is to exam...

journal_title：Neuropsychobiology

authors： Hueppe M,Hartge D,Stoll KD,Ros A,Schmucker P,Gerlach K

更新日期：2011-01-01 00:00:00

abstract：:Plasma noradrenaline (NA), adrenaline (Ad), dopamine (DA), platelet serotonin (p5HT), free serotonin (f5HT), glucose, heart rate (HR) and blood pressure (BP) were measured before and after an oral load of glucose (OGTT) in 100 normal humans. One sham-feeding test was performed in every subject 2-3 weeks before OGTT. A...

journal_title：Neuropsychobiology

authors： Lechin F,van der Dijs B,Lechin M,Báez S,Jara H,Lechin A,Orozco B,Rada I,Cabrera A,Jiménez V

更新日期：1992-01-01 00:00:00