Cyclic AMP levels in cerebrospinal fluid in manic-melancholic patients.

Abstract:

:The concentrations of adenosine 3'5'-cyclic monophosphate (cyclic AMP) in cerebrospinal fluid (CSF) in manic-melancholic patients were studied. As control groups served patients suffering from other psychiatric disorders as well as neruological and orthopedic patients. The results showed no difference between the various diagnostic groups, including melancholic versus manic patients, unipolar versus bipolar types. The severity of the affective states measured by rating scales showed no correlation to cyclic AMP levels in CSF. The cyclic AMP levels were apparently not influenced by electroconvulsive therapy or treatment with lithium, neuroleptica, or tricyclic antidepressants.

journal_name

Neuropsychobiology

journal_title

Neuropsychobiology

authors

Geisler A,Bech P,Johannesen M,Rafaelsen OJ

doi

10.1159/000117548

subject

Has Abstract

pub_date

1976-01-01 00:00:00

pages

211-20

issue

4

eissn

0302-282X

issn

1423-0224

journal_volume

2

pub_type

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