Schizophrenia susceptibility and HL-A antigen.

abstract：BACKGROUND:Psychosis spectrum disorders, especially schizophrenia, have been linked to disturbed dopaminergic activity in the brain. Plasma homovanillic acid (pHVA) levels partly represent dopaminergic metabolism in the central nervous system. In the present study associations between (changes in) pHVA levels, symptom ...

journal_title：Neuropsychobiology

authors： van de Kerkhof NW,Fekkes D,van der Heijden FM,Egger JI,Verhoeven WM

更新日期：2015-01-01 00:00:00

abstract：:We have previously shown that the tilt aftereffect (TAE) appears to respond to changes in central dopaminergic function. In this study, the TAE was investigated during the preovulatory and the premenstrual phases of the menstrual cycle. Results in the preovulatory phase mimicked those previously found associated with ...

journal_title：Neuropsychobiology

authors： Symons E,Calvert JE,Snelgar RS,Harris JP

更新日期：1990-01-01 00:00:00

abstract：:Substance P (SP) is a neuropeptide which is abundant in the periphery and the central nervous system, where it is colocalized with other neurotransmitters such as serotonin or dopamine. SP has been proposed to play a role in the regulation of pain including migraine and fibromyalgia, asthma, inflammatory bowel disease...

journal_title：Neuropsychobiology

authors： Lieb K,Treffurth Y,Berger M,Fiebich BL

更新日期：2002-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled, multiple-ascending-dose study, the encephalotropic and psychotropic properties of ABIO-08/01, a new potentially anxiolytic and nootropic isoxazoline, were studied in 16 young healthy males. In a randomized nonbalanced phase 1 study, they received 3 oral drug doses (10, 20, 40 mg)...

journal_title：Neuropsychobiology

authors： Saletu-Zyhlarz GM,Anderer P,Wolzt M,Semlitsch HV,Assandri A,Nessi P,Nannipieri F,Rosini S,Saletu B

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:In general, humans tend to discount the value of delayed reward. An increase in the rate of discounting leads to an inability to select a delayed reward over a smaller immediate reward (reward-delay impulsivity). Although deficits in the serotonergic system are implicated in this reward-delay impulsivit...

journal_title：Neuropsychobiology

authors： Demoto Y,Okada G,Okamoto Y,Kunisato Y,Aoyama S,Onoda K,Munakata A,Nomura M,Tanaka SC,Schweighofer N,Doya K,Yamawaki S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Depressive disorder (DD) is characterized by an inflammatory process and oxidative stress. Cyclooxygenase-2 (COX-2), the expression of which increases in depression, is an enzyme involved in inflammation and free radical processes. The aim of our study was to assess the correlation between single nucleotide ...

journal_title：Neuropsychobiology

authors： Gałecki P,Florkowski A,Bieńkiewicz M,Szemraj J

更新日期：2010-01-01 00:00:00

abstract：:Urinary 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in 53 depressed women were compared to current suicidal thoughts or activity. Comparisons were also made between MHPG and past suicide attempts, number of past attempts, and seriousness of the worst attempt. There was a weak trend for current but not past suicidali...

journal_title：Neuropsychobiology

authors： Garvey MJ,Hollon SD,Tuason VB

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND AIM:Repetitive transcranial magnetic stimulation (rTMS) is supposed to be not as effective in severe depression as it is in medium depression. We evaluated the treatment response to an ultra-high-frequency (UHF; 30 Hz) approach, which was used to maximize the rTMS efficacy in severely ill patients. METH...

journal_title：Neuropsychobiology

authors： Ullrich H,Kranaster L,Sigges E,Andrich J,Sartorius A

更新日期：2012-01-01 00:00:00

abstract：:It has been 60 years since Cade first described patients who responded to antimanic lithium treatment. Two decades later, responders to lithium stabilization emerged in larger numbers. The responses of many severely ill bipolar patients to lithium were striking and called for an explanation. Remarkable reactions to a ...

journal_title：Neuropsychobiology

authors： Grof P

更新日期：2010-01-01 00:00:00

abstract：:In contrast to the single-channel dimensional complexity, the global dimensional complexity is calculated from a multichannel EEG. The intention with the method is to measure the spatial distribution of information processing in the brain. The method seems to be of interest in psychopharmacological research, but the i...

journal_title：Neuropsychobiology

authors： Matousek M,Wackermann J,Palus M,Berankova A,Albrecht V,Dvorak I

更新日期：1995-01-01 00:00:00

abstract：:In 63 depressed patients, the associations between severity of depression, psychomotor retardation, assessed by the Bech-Rafaelsen Melancholia Scale, and EEG spectral analysis were examined. Slow EEG activity (theta 2/alpha 1 bands) was positively and fast activity (alpha 3/beta bands) negatively correlated with the o...

journal_title：Neuropsychobiology

authors： Nieber D,Schlegel S

更新日期：1992-01-01 00:00:00

abstract：:Cardiovascular measurements were used as indicators of autonomic arousal during an orthostatic challenge test without medication and after a test dose of 150 mg perazine in 20 acute schizophrenic patients. Unmedicated schizophrenics showed elevated heart rates and elevated systolic and diastolic blood pressure in comp...

journal_title：Neuropsychobiology

authors： Volz HP,Mackert A,Diefenbacher A,Friedrich A,Gaebel W,Müller H,Stock G,Möller HJ

更新日期：1994-01-01 00:00:00

abstract：:The peripheral blood platelets of schizophrenic patients were isolated, and the level of the platelet-associated antibodies (SPAA) was correlated with the rating scores of discrete schizophrenic symptom clusters evaluated with the Brief Psychiatric Rating Scale. Irrespective of medication and gender, symptom-dependent...

journal_title：Neuropsychobiology

authors： Sinyakov MS,Kessler B,Karp L,Weizman A,Kessler AR

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that altered immune responses play a role in the pathogenesis of autism spectrum disorders (ASD), together with dysfunction of the serotonergic and glutamatergic systems. Since the kynurenine (KYN) pathway that degrades tryptophan (TRP) is activated in various neuroinflammatory s...

journal_title：Neuropsychobiology

authors： Bryn V,Verkerk R,Skjeldal OH,Saugstad OD,Ormstad H

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:Recent findings suggest an involvement of insulin-like growth factor-1 (IGF-1) in the pathogenesis of many psychiatric disorders; however, there is a lack of data regarding IGF-1 in patients with obsessive-compulsive disorder (OCD). The aims of the present study were (1) to analyze putative alterations ...

journal_title：Neuropsychobiology

authors： Rosso G,Zanardini R,Chiodelli DF,Ferrari C,Gennarelli M,Bocchio-Chiavetto L

更新日期：2016-01-01 00:00:00

abstract：:Quantitative assessment of regional cerebral blood flow (rCBF) was performed in a 22-year-old man with intractable temporal lobe epilepsy on long-term high-dose phenytoin (PHT) therapy, using single photon emission computed tomography (SPECT) with N-isopropyl-(iodine-123)-p-iodoamphetamine. In all the SPECT scans repe...

journal_title：Neuropsychobiology

authors： Jibiki I,Kido H,Yamaguchi N,Matsuda H,Hisada K

更新日期：1993-01-01 00:00:00

abstract：:The effects of two benzodiazepines (alprazolam and bromazepam) on performance and event-related brain potentials (ERPs) in visual search and verbal recognition memory paradigms were tested in a placebo-controlled double-blind paradigm employing 12 young healthy subjects. Both drugs exerted similar effects on performan...

journal_title：Neuropsychobiology

authors： Münte TF,Gehde E,Johannes S,Seewald M,Heinze HJ

更新日期：1996-01-01 00:00:00

abstract：:Neural-network pattern classifiers were used to study the effects of long half-life flurazepam (30 mg) and quazepam (15 mg), and short half-life triazolam (0.5 mg) on non-REM sleep. We measured the magnitude of effect, time course, and EEG spectral signature of the three benzodiazepines as a function of third-of-night...

journal_title：Neuropsychobiology

authors： Gevins AS,Stone RK,Ragsdale SD

更新日期：1988-01-01 00:00:00

abstract：:In 60 patients, hospitalized for a depressive syndrome, visual average evoked potentials (V .AEP) to stimuli of different intensities and the occurrence of life-events during the last year, as assessed by means of a specially constructed questionnaire, were investigated. Patients with an augmenter response in V .AEP, ...

journal_title：Neuropsychobiology

authors： von Knorring L,Jacobsson L,Perris C,Perris H

更新日期：1980-01-01 00:00:00

abstract：:Serum dopamine-beta-hydroxylase (DBH) levels were assessed in 150 depressed patients of both sexes, with a mean age of 44.0 +/- 12.3 (SD) years. Patients were divided into unipolars (n = 46), bipolars (n = 25), neurotic-reactive (n = 46) and unspecified (n = 38) i.e., those who did not fit into any of the previous cat...

journal_title：Neuropsychobiology

authors： Eisemann M,Ericsson U,Von Knorring L,Perris C,Perris H,Ross S

更新日期：1983-01-01 00:00:00

abstract：:Supine and standing heart rate (HR) and blood pressure measures were compared among 19 nonsmoking normal controls, 29 smoking patients and 36 nonsmoking patients with panic disorder. The smoking patients had a significantly higher supine HR, standing diastolic blood pressure, standing mean blood pressure and supine an...

journal_title：Neuropsychobiology

authors： Yeragani VK,Pohl R,Balon R,Ramesh C,Glitz D,Sherwood P

更新日期：1990-01-01 00:00:00

abstract：:Based on 5-HT hypothesis, L-5-HTP (150 or 300 mg/day) was given orally to 18 depressed patients. The global estimates were 2 very much improved; 8 much improved; 3 minimally improved, and 5 unchanged. The action of L-5-HTP was usually rapid. The elevation of the serum 5-HT level 1 week after L-5-HTP administration was...

journal_title：Neuropsychobiology

authors： Kaneko M,Kumashiro H,Takahashi Y,Hoshino Y

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Structural brain changes and cognitive impairments have been identified as indicators of genetic risk for schizophrenia. However, the pattern of associations between such structural and functional liability markers has been less well investigated. METHODS:Magnetic resonance imaging data and cognitive assess...

journal_title：Neuropsychobiology

authors： Habets P,Krabbendam L,Hofman P,Suckling J,Oderwald F,Bullmore E,Woodruff P,Van Os J,Marcelis M

更新日期：2008-01-01 00:00:00

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for many neurotransmitter receptors. Among the adverse effects of clozapine, urinary incontinence is commonly found and is suggested to be caused by alpha-adrenergic blockade. We tested the hypothesis that clozapine-induced urinary incontinence is...

journal_title：Neuropsychobiology

authors： Hsu JW,Wang YC,Lin CC,Bai YM,Chen JY,Chiu HJ,Tsai SJ,Hong CJ

更新日期：2000-01-01 00:00:00

abstract：:A potential candidate gene that could contribute to the education process is the apolipoprotein E (apo E) gene that has been shown to correlate with memory function and memory decline. We measured apo E polymorphism in groups of probands with different levels of education selected from a population sample. In the grou...

journal_title：Neuropsychobiology

authors： Hubacek JA,Pitha J,Skodová Z,Adámková V,Lánská V,Poledne R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Patients with bipolar disorder are at a high risk for becoming obese. Adipokines are associated with depression and obesity via the inflammatory process. However, few studies have investigated the associations between depression and leptin, adiponectin and resistin levels in patients with bipolar disorder. W...

journal_title：Neuropsychobiology

authors： Lee HJ,Kim SH,Kim EY,Lee NY,Yu HY,Kim YS,Ahn YM

更新日期：2014-01-01 00:00:00

abstract：:Clinical observations have suggested that lithium may exert adverse effects on memory. The difficulty in achieving empirical consensus regarding this issue has reflected several methodological problems: diversity of research designs, heterogeneous samples, lack of control groups and the possible confounding of memory ...

journal_title：Neuropsychobiology

authors： Engelsmann F,Ghadirian AM,Grof P

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The present study investigated the effects of rapid tryptophan depletion (RTD), and the ensuing reduction of central nervous system levels of serotonin (5-HT), upon reactive aggression in patients with attention deficit/hyperactivity disorder (ADHD). Furthermore, it was asked whether the relation between 5-H...

journal_title：Neuropsychobiology

authors： Stadler C,Zepf FD,Demisch L,Schmitt M,Landgraf M,Poustka F

更新日期：2007-01-01 00:00:00

abstract：:The medical histories of 600 psychotic and 369 nonpsychotic subjects were examined for the occurrence of rheumatic chorea. There was significantly more rheumatic chorea in the histories of psychotic patients than in nonpsychotics (p less than 0.01, chi-square). Neuropathological associations are discussed. ...

journal_title：Neuropsychobiology

authors： Wilcox JA,Nasrallah HA

更新日期：1986-01-01 00:00:00

abstract：:Like the industry, the medical profession takes now an interest in quality assurance programs. In the field of psychiatry, the quality assessment of antidepressive drug prescriptions is an ideal target. A brief review of previous studies reveals a high prevalence of the use of psychotropes among the general population...

journal_title：Neuropsychobiology

authors： Wilmotte J

更新日期：1989-01-01 00:00:00