Effects of alprazolam and bromazepam on visual search and verbal recognition memory in humans: a study with event-related brain potentials.

abstract：OBJECTIVES:Corticotropin-releasing factor (CRF) plays a prominent role in mediating the effect of stressors on the hypothalamic-pituitary-adrenal axis. In this study, we examined the effects of chronic administration of second-generation antipsychotic drug ziprasidone on CRF mRNA expression in the hypothalamic paravent...

journal_title：Neuropsychobiology

authors： Park SW,Choi SM,Lee JG,Lee CH,Lee SJ,Kim NR,Kim YH

更新日期：2011-01-01 00:00:00

abstract：:Twenty-three chronic undifferentiated schizophrenics, 13 women and 10 men, aged 37-64 years with 15-to 40-year histories of the disease were given either thyrotropin-releasing hormone (TRH) (10 subjects) or DDAVP (13 subjects) with the aim to improve the negative symptoms of the disease and memory. TRH (600 micrograms...

journal_title：Neuropsychobiology

authors： Brambilla F,Aguglia E,Massironi R,Maggioni M,Grillo W,Castiglioni R,Catalano M,Drago F

更新日期：1986-01-01 00:00:00

abstract：:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical import...

journal_title：Neuropsychobiology

authors： Refsum HE,Astrup C

更新日期：1980-01-01 00:00:00

abstract：:This study was conducted to elucidate the effects of electroconvulsive therapy (ECT) on frontal white matter in late-life depressed patients. Diffusion tensor imaging was performed on 8 late-life depressed patients and 12 healthy age-matched controls. The patients were scanned before and after a course of ECT. Fractio...

journal_title：Neuropsychobiology

authors： Nobuhara K,Okugawa G,Minami T,Takase K,Yoshida T,Yagyu T,Tajika A,Sugimoto T,Tamagaki C,Ikeda K,Sawada S,Kinoshita T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The availability of tobacco products is associated with the likelihood that adolescents will begin using tobacco. Yet the relationship between nicotine availability and voluntary consumption has not been tested experimentally in developing rats. METHOD:The impact of environmental availability on adolescent ...

journal_title：Neuropsychobiology

authors： Biondolillo KD,Pearce AR

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:So-called Porteus mazes are used to investigate prefrontal cortex (PFC) functioning in normal subjects and patients with different neuropsychiatric disorders. Here we present data confirming the involvement of the PFC for the first time by means of functional magnetic resonance imaging (fMRI). To minimize mo...

journal_title：Neuropsychobiology

authors： Kirsch P,Lis S,Esslinger C,Gruppe H,Danos P,Broll J,Wiltink J,Gallhofer B

更新日期：2006-01-01 00:00:00

abstract：:Performance on temporal discrimination of time intervals in the range of milliseconds is interpreted by the assumption of an internal clock; the higher the clock rate the better the temporal resolution of the internal clock will be, which is equivalent to more accuracy in timing of brief intervals. Although there is s...

journal_title：Neuropsychobiology

authors： Rammsayer TH,Vogel WH

更新日期：1992-01-01 00:00:00

abstract：:Apomorphine, a dopamine receptor agonist (given in a dose of 0.75 mg s.c.), was administered to 8 healthy volunteers; electroencephalograph (EEG) and event-related potential (ERP) mapping were performed before dosing and 0.5, 1.5 and 2.5 h after dosing. Apomorphine caused an overall increase in beta activity at time 0...

journal_title：Neuropsychobiology

authors： Luthringer R,Rinaudo G,Toussaint M,Bailey P,Muller G,Muzet A,Macher J

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The polymorphisms of serotonergic genes (5-HTTLPR and HTR1A rs6295) and separation life events have been studied to find an association with panic disorder, respectively. However, there are no studies that have yet evaluated the interaction effect between serotonergic genes and separation life events for pan...

journal_title：Neuropsychobiology

authors： Choe AY,Kim B,Lee KS,Lee JE,Lee JY,Choi TK,Lee SH

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Oxytocin interacts with the dopaminergic system, which plays a role in addiction behaviors. The association between oxytocin and addiction was confirmed in animal studies. Novelty seeking is one of the predictors and indicators of drug addiction. The aim of the present study was to probe the association betw...

journal_title：Neuropsychobiology

authors： Lin SH,Lee LT,Tsai HC,Chen KC,Chen WT,Lee IH,Lu RB,Chen PS,Yang YK

更新日期：2015-01-01 00:00:00

abstract：:The effects of the dopaminergic agonists (L-dopa, pergolide) and antagonists (haloperidol, clozapin) and a cholinergic agonist (tacrine) and antagonist (mecamylamine) on the voluntary intake of nicotine were investigated with the 2-bottle paradigm with the test drugs being dissolved directly in the drinking fluid of t...

journal_title：Neuropsychobiology

authors： Kameda G,Dadmarz M,Vogel WH

更新日期：2000-01-01 00:00:00

abstract：:The authors recorded contingent negative variation (CNV) in a group of subjects affected by presenile dementia, at the onset of the symptoms, with a slight degree of intellectual deterioration. Recordings were carried out in rest basal conditions and upon administration of an insignificant distracting stimulus. Result...

journal_title：Neuropsychobiology

authors： Rizzo PA,Albani G,Cicardi C,Spadaro M,Morocutti C

更新日期：1984-01-01 00:00:00

abstract：:Six WHO Collaborating Centre took part in the study of the antithymic activity of blood sera of patients suffering from schizophrenia. Blood serum specimens from 118 schizophrenic patients and 62 mentally healthy donors were investigated. Statistically significant differences between schizophrenic patients and the con...

journal_title：Neuropsychobiology

authors： Koliaskina G,Tsutsulkovskaya M,Domashneva I,Maznina T,Kielholz P,Gastpar M,Bunney W,Rafaelsen O,Heltberg J,Coppen A,Hippius H,Hoecherl B,Vartanian F

更新日期：1980-01-01 00:00:00

abstract：:Eight patients with chronic obsessive-compulsive neurosis were subjected to trazodone, an antidepressant acting on the serotonergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement ha...

journal_title：Neuropsychobiology

authors： Prasad A

更新日期：1986-01-01 00:00:00

abstract：:We report 3 patients who experienced nonconvulsive status epilepticus following generalized convulsions during antidepressant treatment. All showed prolonged confusion with some psychiatric symptoms, and their electroencephalograms (EEGs) showed either bilateral synchronous multiple spike wave discharges or continuous...

journal_title：Neuropsychobiology

authors： Yoshino A,Watanabe M,Shimizu K,Goto T,Ichinowatari N,Yoshimasu H,Masaki K,Aoyama T,Hara T

更新日期：1997-01-01 00:00:00

abstract：:Analysis of the mechanisms underlying the clinical effects of different drugs is a vital part of psychopharmacology. It is fair to say, however, that such analyses have thus far met with little success. This lack of success can be traced to a variety of sources that have flawed the analytical process itself. Detailed ...

journal_title：Neuropsychobiology

authors： Carlton PL

更新日期：1984-01-01 00:00:00

abstract：:The effects of zolpidem or zaleplon on sleep architecture, respiratory patterns and performance were assessed at a simulated altitude of 4,000 m. Twelve male healthy subjects spent 4 nights in a decompression chamber, 1 at sea level (baseline), 3 at 4,000 m to test zolpidem (10 mg), zaleplon (10 mg) and placebo, given...

journal_title：Neuropsychobiology

authors： Beaumont M,Batéjat D,Coste O,Van Beers P,Colas A,Clère JM,Piérard C

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Structural brain changes and cognitive impairments have been identified as indicators of genetic risk for schizophrenia. However, the pattern of associations between such structural and functional liability markers has been less well investigated. METHODS:Magnetic resonance imaging data and cognitive assess...

journal_title：Neuropsychobiology

authors： Habets P,Krabbendam L,Hofman P,Suckling J,Oderwald F,Bullmore E,Woodruff P,Van Os J,Marcelis M

更新日期：2008-01-01 00:00:00

abstract：:Saliva cortisol was measured at 11 p.m. in a sample of 74 psychiatric inpatients composed of 24 primary endogenous depressives, 40 secondary depressives and 20 nondepressives (DSM III and Saint-Louis criteria). Primary depressives had significantly higher 11 p.m. saliva cortisol levels than nondepressives (p less than...

journal_title：Neuropsychobiology

authors： Guéchot J,Lépine JP,Cohen C,Fiet J,Lempérière T,Dreux C

更新日期：1987-01-01 00:00:00

abstract：:Genetic polymorphism of the serotonin 5-HT(2A) receptor seems to be associated with therapeutic response to selective serotonin reuptake inhibitors (SSRIs). The present study investigated whether a novel -1438G/A polymorphism in the promoter region of the 5-HT(2A )receptor gene is associated with therapeutic response ...

journal_title：Neuropsychobiology

authors： Sato K,Yoshida K,Takahashi H,Ito K,Kamata M,Higuchi H,Shimizu T,Itoh K,Inoue K,Tezuka T,Suzuki T,Ohkubo T,Sugawara K,Otani K

更新日期：2002-01-01 00:00:00

abstract：:This study investigated the acute effect of a dose range of low-to-moderate binge-like methamphetamine treatments on the regional expression of neurotrophin proteins in the brain and serum 2 h after the last dose, in addition to assessing the behavioural effects and dopamine neurotransmitter changes produced. Male Spr...

journal_title：Neuropsychobiology

authors： Moreira da Silva Santos A,Kelly JP,Doyle KM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Schizophrenia is a genetically complex disorder with an unknown pathophysiology. Several genes implicated in glutamate metabolism have been associated with the disorder. Recent studies of polymorphisms in the dystrobrevin-binding protein 1 gene (DTNBP1; dysbindin) and D-amino-acid-oxidase (DAO) gene, both in...

journal_title：Neuropsychobiology

authors： Wirgenes KV,Djurovic S,Agartz I,Jonsson EG,Werge T,Melle I,Andreassen OA

更新日期：2009-01-01 00:00:00

abstract：:Recent findings indicate that the memory-impairing effects of benzodiazepines may preferentially involve the basolateral nucleus of the amygdala. To test this hypothesis we examined the effects on pretrial injection of diazepam into the central as compared to the lateral/basolateral amygdaloid nuclei on memory for a c...

journal_title：Neuropsychobiology

authors： Silva MA,Tomaz C

更新日期：1995-01-01 00:00:00

abstract：:Cortisol has a modulatory influence on cognitive functions in humans. Both impairing and enhancing effects of cortisol administration have been shown for hippocampus-dependent declarative memory, and impairing effects have been shown for prefrontal-cortex-dependent working memory function. Given the high density of gl...

journal_title：Neuropsychobiology

authors： Kumsta R,Entringer S,Koper JW,van Rossum EF,Hellhammer DH,Wüst S

更新日期：2010-01-01 00:00:00

abstract：:To examine volumetric abnormality, the caudate nucleus was measured in patients with schizophrenia and healthy subjects using magnetic resonance imaging. The absolute and relative volumes of white matter in the caudate nucleus were found to be significantly smaller in patients with schizophrenia compared to those in h...

journal_title：Neuropsychobiology

authors： Takase K,Tamagaki C,Okugawa G,Nobuhara K,Minami T,Sugimoto T,Sawada S,Kinoshita T

更新日期：2004-01-01 00:00:00

abstract：:Three anxiolytic drugs (bromazepam 3 mg, buspirone 10 mg, and clobazam 10 mg p.o.) were evaluated for their effects on memory, psychomotor performance and subjective response in a double-blind, placebo-controlled, crossover study in 20 healthy volunteers. At each session, measurements were made before and 2 and 6 h af...

journal_title：Neuropsychobiology

authors： Bourin M,Auget JL,Colombel MC,Larousse C

更新日期：1989-01-01 00:00:00

abstract：:Urinary 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in 53 depressed women were compared to current suicidal thoughts or activity. Comparisons were also made between MHPG and past suicide attempts, number of past attempts, and seriousness of the worst attempt. There was a weak trend for current but not past suicidali...

journal_title：Neuropsychobiology

authors： Garvey MJ,Hollon SD,Tuason VB

更新日期：1994-01-01 00:00:00

abstract：:In the present study, the effects of short-acting benzodiazepines on nocturnal sleep and the carryover effects of these drugs were studied. The study involved 10 young, healthy male subjects who had given their written informed consent to participate. Either a placebo (PLA), 0.125 mg triazolam (TRZ), 0.25 mg TRZ or 0....

journal_title：Neuropsychobiology

authors： Suzuki H,Yamadera H,Asayama K,Kudo Y,Ito T,Tamura Y,Endo S

更新日期：2003-01-01 00:00:00

abstract：:In two studies experimentally induced colds slowed the speed of response in a serial reaction task. Responding was also slower during the incubation period of the illness, which shows that performance on such a task may be used to predict subsequent illness. Volunteers who had no significant clinical illness, but who ...

journal_title：Neuropsychobiology

authors： Smith AP,Tyrrell DA,Al-Nakib W,Coyle KB,Donovan CB,Higgins PG,Willman JS

更新日期：1987-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled study the effect of nocturnal traffic noise and bedtime medication of a new benzodiazepine, OX-373, on objective and subjective sleep variables as well as on the quality of morning awakenings was investigated. 10 healthy subjects spent 17 nights in the sleep laboratory: 2 adaptati...

journal_title：Neuropsychobiology

authors： Saletu B,Grünberger J

更新日期：1981-01-01 00:00:00