Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia.

abstract：:In the present study, single-unit extracellular recording was used in male Wistar rats to compare the effects of a single dose (acute treatment) and a 21-day regimen (long-term treatment) with clomipramine (2.5 mg/kg) and fluoxetine (1.0 mg/kg) on the spontaneous firing rate of nucleus accumbens (NAcc) neurons connect...

journal_title：Neuropsychobiology

authors： Rodríguez-Landa JF,Contreras CM,Gutiérrez-García AG,Bernal-Morales B

更新日期：2003-01-01 00:00:00

abstract：:The International Pharmaco-EEG Society (IPEG) presents updated guidelines summarising the requirements for the recording and computerised evaluation of pharmaco-EEG data in man. Since the publication of the first pharmaco-EEG guidelines in 1982, technical and data processing methods have advanced steadily, thus enhanc...

journal_title：Neuropsychobiology

authors： Jobert M,Wilson FJ,Ruigt GS,Brunovsky M,Prichep LS,Drinkenburg WH,IPEG Pharmaco-EEG Guidelines Committee.

更新日期：2012-01-01 00:00:00

abstract：:In 63 depressed patients, the associations between severity of depression, psychomotor retardation, assessed by the Bech-Rafaelsen Melancholia Scale, and EEG spectral analysis were examined. Slow EEG activity (theta 2/alpha 1 bands) was positively and fast activity (alpha 3/beta bands) negatively correlated with the o...

journal_title：Neuropsychobiology

authors： Nieber D,Schlegel S

更新日期：1992-01-01 00:00:00

abstract：:Acute quantitative electroencephalographic effects of cigarette smoking were examined in 15 smokers within a repeated-measures design which assessed changes in power-spectral estimates following acute pre-treatment with placebo, a dose (20 mg) of mecamylamine, a dose (0.6 mg) of scopolamine and a combined dose of meca...

journal_title：Neuropsychobiology

authors： Knott VJ,Harr A,Ilivitsky V,Mahoney C

更新日期：1998-01-01 00:00:00

abstract：:Analysis of the mechanisms underlying the clinical effects of different drugs is a vital part of psychopharmacology. It is fair to say, however, that such analyses have thus far met with little success. This lack of success can be traced to a variety of sources that have flawed the analytical process itself. Detailed ...

journal_title：Neuropsychobiology

authors： Carlton PL

更新日期：1984-01-01 00:00:00

abstract：:The relationship between physical activity and mental health has been widely investigated, and several hypotheses have been formulated about it. Specifically, during the aging process, physical exercise might represent a potential adjunctive treatment for neuropsychiatric disorders and cognitive impairment, helping de...

journal_title：Neuropsychobiology

authors： Deslandes A,Moraes H,Ferreira C,Veiga H,Silveira H,Mouta R,Pompeu FA,Coutinho ES,Laks J

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Memory processes, as reflected by 'old/new' effects of event-related potentials (ERPs), have been shown to be impaired in depressed patients. This variability might be partly explained by biological factors. S100B is a glial calcium-binding protein with neuroplastic properties; S100B serum levels have been sh...

journal_title：Neuropsychobiology

authors： Zhang Y,Rothermundt M,Peters M,Wiesmann M,Hoy L,Arolt V,Emrich HM,Dietrich DE

更新日期：2009-01-01 00:00:00

abstract：:Cerebral impedance changes (F changes) indicating cerebral blood flow variations in the central and precentral areas were measured with a rheographic technique in normal subjects preparing for and carrying out a motor task. The time course of the F changes was studied and several significant correlations were establis...

journal_title：Neuropsychobiology

authors： Jacquy J,Piraux A,Jocquet P,Lhoas JP,Noel G

更新日期：1977-01-01 00:00:00

abstract：:Somatosensory event-related potentials (SERP) were recorded in 30 chronic young schizophrenic patients and in 15 age-matched controls. Objective SERP parameters were latencies, amplitudes and the determination of areas of the cognitive components N1 and P3 by integration. Highly significantly reduced areas and prolong...

journal_title：Neuropsychobiology

authors： Böning J,Drechsler F,Neuhauser B

更新日期：1989-01-01 00:00:00

abstract：:Human personality traits, which are substantially heritable, may be modulated by monoamine neurotransmitters. It has been demonstrated that the catechol-O-methyltransferase (COMT) Val158Met genetic polymorphism, a functional polymorphism that may affect monoamine metabolism, is possibly associated with specific person...

journal_title：Neuropsychobiology

authors： Tsai SJ,Hong CJ,Yu YW,Chen TJ

更新日期：2004-01-01 00:00:00

abstract：:Actions of the new antiepileptic drug lamotrigine (LTG) were characterized using extracellular and whole cell patch clamp recordings from rat CA1 and CA3 pyramidal cells in vitro. The results suggest that LTG, beside its previously described effect on the fast sodium inward current, also modulates - presumably voltage...

journal_title：Neuropsychobiology

authors： Grunze H,von Wegerer J,Greene RW,Walden J

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:In depressed patients, overstimulation of the hypothalamo-pituitary-adrenocortical (HPA) system, probably caused by glucocorticoid receptor resistance, is the most consistent neurobiological finding. Glucocorticoids themselves are reported to increase leptin synthesis and secretion in humans. METHODS:We exa...

journal_title：Neuropsychobiology

authors： Himmerich H,Zimmermann P,Ising M,Kloiber S,Lucae S,Kunzel HE,Binder EB,Holsboer F,Uhr M

更新日期：2007-01-01 00:00:00

abstract：:To clarify the circadian aspects of delayed sleep phase syndrome (DSPS) in 4 patients with DSPS, we recorded polysomnograms and rectal temperature before and after chronotherapy. The time interval (2.7 h) between sleep onset and rectal temperature minimum before chronotherapy was shorter than the time interval after c...

journal_title：Neuropsychobiology

authors： Ozaki N,Iwata T,Itoh A,Kogawa S,Ohta T,Okada T,Kasahara Y

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND/AIMS:Neurotrophins such as brain-derived neurotrophic factor (BDNF) are vital for neuronal survival and adaptive plasticity. With high BDNF gene expression in the prefrontal cortex, BDNF is a potential regulatory factor for building and maintaining cognitive reserves. Recent studies suggest that individual d...

journal_title：Neuropsychobiology

authors： Koven NS,Collins LR

更新日期：2014-01-01 00:00:00

abstract：:The search for specific predepressive personality factors has a long tradition in psychiatry. Studies in which assessments were made prospectively, before the onset of a first-ever episode of the illness, are, however, rare. In the present report from the Lundby Study we have investigated premorbid, mainly personality...

journal_title：Neuropsychobiology

authors： Rorsman B,Gräsbeck A,Hagnell O,Isberg PE,Otterbeck L

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Lithium augmentation is a first-line strategy for depressed patients resistant to antidepressive therapy, but little is known about patients' subsequent long-term course or outcome predictors. We investigated long-term outcomes of unipolar depressed patients who had participated in a study on the effects of ...

journal_title：Neuropsychobiology

authors： Adli M,Bschor T,Bauer M,Lucka C,Lewitzka U,Ising M,Uhr M,Mueller-Oerlinghausen B,Baethge C

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Reaction time variability (RTV) is considered a valid endophenotype of attention deficit/hyperactivity disorder (ADHD). It is also often used to examine the efficacy of drug treatment or individual patients' treatment responses and has been furthermore suggested to significantly reduce the potential number o...

journal_title：Neuropsychobiology

authors： Grant P,Kuepper Y,Wielpuetz C,Hennig J

更新日期：2014-01-01 00:00:00

abstract：:The effects of febarbamat and pipamperon on agitational and aggressive states of patients with diffuse psycho-organic syndrome were compared in a double-blind study on patients over 60 years of age requiring nursing care. Such disorders, particularly in the field of psychiatric gerontology, represent an increasing pro...

journal_title：Neuropsychobiology

authors： Brenner HD,Alberti L,Keller F,Schaffner L

更新日期：1984-01-01 00:00:00

abstract：:Abnormal anterior pituitary responsiveness to acute administration of thyrotropin-releasing hormone was investigated in 8 patients, 6 women and 2 men, with primary affective disorders in a depressive phase and in 2 women with schizoaffective disorders. Thyrotropin-releasing hormone, 500 micrograms i.v., induced a rise...

journal_title：Neuropsychobiology

authors： Brambilla F,Scarone S,Massironi R,Nobile P,Pugnetti L

更新日期：1982-01-01 00:00:00

abstract：:The aim of this paper was to determine whether the prolonged decrease in seizure threshold produced by chemical kindling was accompanied by behavioural changes in tests of anxiety and aggression. The responses of rats in five tests were examined after chronic treatment with the benzodiazepine inverse agonist FG7142. T...

journal_title：Neuropsychobiology

authors： Taylor SC,Johnston AL,Wilks LJ,Nicholass JM,File SE,Little HJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:In alcohol and other substance dependencies, patients often suffer relapse despite better knowledge and their intention to remain abstinent. A variety of neurotransmitter systems and their respective alterations due to the chronic drug intake are involved in mechanisms that facilitate relapse. It has been po...

journal_title：Neuropsychobiology

authors： Garbusow M,Sebold M,Beck A,Heinz A

更新日期：2014-01-01 00:00:00

abstract：:During interictal periods in 9 patients with partial epilepsy we examined whether there were correlations between the relative power of background EEG (power spectral analysis) and the absolute values of regional cerebral blood flow (rCBF) measured by 99mTc hexamethylpropylene amine oxime (HMPAO) SPECT in each cerebra...

journal_title：Neuropsychobiology

authors： Jibiki I,Kurokawa K,Fukushima T,Kido H,Yamaguchi N,Matsuda H,Hisada K

更新日期：1994-01-01 00:00:00

abstract：:The brain activity of 13 right-handed students (6 men and 7 women) was determined using high resolution (99m)Tc-HMPAO brain SPECT images during visuospatial tasks. The results showed that there was no significant gender-specific difference in solving the visuospatial tasks and that no meaningful statistical difference...

journal_title：Neuropsychobiology

authors： Unterrainer J,Wranek U,Staffen W,Gruber T,Ladurner G

更新日期：2000-01-01 00:00:00

abstract：:Like the industry, the medical profession takes now an interest in quality assurance programs. In the field of psychiatry, the quality assessment of antidepressive drug prescriptions is an ideal target. A brief review of previous studies reveals a high prevalence of the use of psychotropes among the general population...

journal_title：Neuropsychobiology

authors： Wilmotte J

更新日期：1989-01-01 00:00:00

abstract：:Cardiovascular measurements were used as indicators of autonomic arousal during an orthostatic challenge test without medication and after a test dose of 150 mg perazine in 20 acute schizophrenic patients. Unmedicated schizophrenics showed elevated heart rates and elevated systolic and diastolic blood pressure in comp...

journal_title：Neuropsychobiology

authors： Volz HP,Mackert A,Diefenbacher A,Friedrich A,Gaebel W,Müller H,Stock G,Möller HJ

更新日期：1994-01-01 00:00:00

abstract：:The formerly designed method for quantitative evaluation of drug effects in rats is employed for the classification of three different neuroleptic drugs, namely sulpiride, clozapine and haloperidol. Analysis of the power density spectra as obtained from the recorded activity in the cortex, striatum and reticular core ...

journal_title：Neuropsychobiology

authors： Dimpfel W,Decker H

更新日期：1985-01-01 00:00:00

abstract：:Plasma levels of free and conjugated 3,4-dihydroxyphenylethyleneglycol (DOPEG), the main deaminated metabolite of norepinephrine, were assayed in 48 depressed patients before initiating a treatment with either maprotiline, an inhibitor of norepinephrine reuptake, or indalpine, a specific inhibitor of serotonin reuptak...

journal_title：Neuropsychobiology

authors： Lôo H,Benkelfat C,Poirier MF,Vanelle JM,Olié JP,Dennis T,Scatton B

更新日期：1986-01-01 00:00:00

abstract：:28 cases of suicide committed in a Swedish population subjected to repeated psychiatric investigations are described. Two groups of controls were selected from the same population: sex- and age-matched living persons (normal group) and sex-matched persons who had died from organic disease at ages corresponding to thos...

journal_title：Neuropsychobiology

authors： Hagnell O,Rorsman B

更新日期：1979-01-01 00:00:00

abstract：:A 56-year-old male parkinsonian patient developed a unique behavioral change following the oral administration of cinepazide, a cerebral vasodilator. This behavior consisted of an apparent infatuation with a ward nurse, which ceased after medication was discontinued. ...

journal_title：Neuropsychobiology

authors： Hashimoto A,Hanada M

更新日期：1984-01-01 00:00:00

abstract：:Besides their regulation of the pituitary-adrenal and pituitary-thyroidal axis, respectively, the neurohormones CRH and TRH act within the central nervous system to evoke and modulate a number of behavioral and physiological processes. In particular, an increase in the sympathetic nervous system and respiratory activi...

journal_title：Neuropsychobiology

authors： Lehnert H,Nink M,Mann K,Röschke J,Hellhammer DH

更新日期：1993-01-01 00:00:00