Leptin is associated with mood status and metabolic homeostasis in patients with bipolar disorder.

abstract：:Monoamine oxidase A (MAOA) is a mitochondrial enzyme involved in the degradation of dopamine, serotonin and norepinephrine and these neurotransmitters are hypothesized to be involved in the cognitive function of humans. This study of a cohort of 191 healthy young Chinese females attempts to utilize the intelligence qu...

journal_title：Neuropsychobiology

authors： Yu YW,Tsai SJ,Hong CJ,Chen MC,Yang CW,Chen TJ

更新日期：2005-01-01 00:00:00

abstract：:The acute effects of alcohol (0.7 g/kg) on visual signal detection performance and critical flicker fusion frequency (CFF) of normal volunteers were investigated using a signal detection theory analysis. When signal probability was low, alcohol affected the stimulus sensitivity and the reaction times of hits. Under a ...

journal_title：Neuropsychobiology

authors： Jansen AA,de Gier JJ,Slangen JL

更新日期：1985-01-01 00:00:00

abstract：:The present paper is a review of the use of psychophysiology in diagnosis and treatment of simple phobias. The paper begins with a definition and characterization of phobic fears, together with a description of prevalence rates, age onset, and gender differences. Acquisition is then discussed within a Three-Systems mo...

journal_title：Neuropsychobiology

authors： Hugdahl K

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:Corticotropin-releasing factor (CRF) plays a prominent role in mediating the effect of stressors on the hypothalamic-pituitary-adrenal axis. In this study, we examined the effects of chronic administration of second-generation antipsychotic drug ziprasidone on CRF mRNA expression in the hypothalamic paravent...

journal_title：Neuropsychobiology

authors： Park SW,Choi SM,Lee JG,Lee CH,Lee SJ,Kim NR,Kim YH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The rs1344706 single nucleotide polymorphism in the ZNF804A gene is a common variant with strong evidence for association with schizophrenia. Recent studies show an association of rs1344706 with cognitive functioning, and there is some evidence suggesting that the risk allele may increase susceptibility for ...

journal_title：Neuropsychobiology

authors： Van Den Bossche MJ,Docx L,Morrens M,Cammaerts S,Strazisar M,Bervoets C,Smolders S,Depreeuw V,Lenaerts AS,De Rijk P,Del-Favero J,Sabbe BG

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In depressed patients, overstimulation of the hypothalamo-pituitary-adrenocortical (HPA) system, probably caused by glucocorticoid receptor resistance, is the most consistent neurobiological finding. Glucocorticoids themselves are reported to increase leptin synthesis and secretion in humans. METHODS:We exa...

journal_title：Neuropsychobiology

authors： Himmerich H,Zimmermann P,Ising M,Kloiber S,Lucae S,Kunzel HE,Binder EB,Holsboer F,Uhr M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Schizophrenia is a genetically complex disorder with an unknown pathophysiology. Several genes implicated in glutamate metabolism have been associated with the disorder. Recent studies of polymorphisms in the dystrobrevin-binding protein 1 gene (DTNBP1; dysbindin) and D-amino-acid-oxidase (DAO) gene, both in...

journal_title：Neuropsychobiology

authors： Wirgenes KV,Djurovic S,Agartz I,Jonsson EG,Werge T,Melle I,Andreassen OA

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:We have investigated the efficacy of high-frequency left (HFL) versus low-frequency right (LFR) repetitive transcranial magnetic stimulation (rTMS) in depression, focusing on specific symptoms as possible predictors of outcome for these two different types of stimulation. METHOD:Seventy-four outpatients wit...

journal_title：Neuropsychobiology

authors： Rossini D,Lucca A,Magri L,Malaguti A,Smeraldi E,Colombo C,Zanardi R

更新日期：2010-01-01 00:00:00

abstract：:Nitric oxide (NO) has been implicated to play a role in the pathogenesis of depressive disorders. Adrenomedullin (AM) induces vasorelaxation by activating adenylate cyclase and also by stimulating the release of NO. AM immune reactivity is present in the brain, consistent with a role as neurotransmitter. Therefore, it...

journal_title：Neuropsychobiology

authors： Savaş HA,Herken H,Yürekli M,Uz E,Tutkun H,Zoroğlu SS,Ozen ME,Cengiz B,Akyol O

更新日期：2002-01-01 00:00:00

abstract：:Performance on temporal discrimination of time intervals in the range of milliseconds is interpreted by the assumption of an internal clock; the higher the clock rate the better the temporal resolution of the internal clock will be, which is equivalent to more accuracy in timing of brief intervals. Although there is s...

journal_title：Neuropsychobiology

authors： Rammsayer TH,Vogel WH

更新日期：1992-01-01 00:00:00

abstract：:Spontaneous and drug-induced locomotor behavior was investigated in rats subjected to lesions of the ventral striatum, using the neurotoxin 6-hydroxydopamine to produce selective depletions of dopamine. Locomotor activity changed with time after lesion. At 2 weeks postoperative less spontaneous rearings were observed ...

journal_title：Neuropsychobiology

authors： Carey RJ,Schwarting R

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:Olfactory processing depends on dopamine metabolism and orbitofrontal cortex functioning, both known to be disturbed in attention-deficit/hyperactivity disorder (ADHD). Some investigations suggested alterations in olfactory processing (identification and sensitivity) in childhood and adult ADHD. METHODS:In t...

journal_title：Neuropsychobiology

authors： Schecklmann M,Schenk E,Maisch A,Kreiker S,Jacob C,Warnke A,Gerlach M,Fallgatter AJ,Romanos M

更新日期：2011-01-01 00:00:00

abstract：:The International Pharmaco-EEG Society (IPEG) presents updated guidelines summarising the requirements for the recording and computerised evaluation of pharmaco-EEG data in man. Since the publication of the first pharmaco-EEG guidelines in 1982, technical and data processing methods have advanced steadily, thus enhanc...

journal_title：Neuropsychobiology

authors： Jobert M,Wilson FJ,Ruigt GS,Brunovsky M,Prichep LS,Drinkenburg WH,IPEG Pharmaco-EEG Guidelines Committee.

更新日期：2012-01-01 00:00:00

abstract：:Personality traits were assessed in a series of 148 patients classified according to Winokur into depression pure disease (DPD), depression spectrum disease (DSD) and sporadic depression (SD) with the addition of a fourth group: family history positive-others (FH + .O) comprised of patients with psychiatric disorders ...

journal_title：Neuropsychobiology

authors： Perris C,Eisemann M,Ericsson U,von Knorring L,Perris H

更新日期：1983-01-01 00:00:00

abstract：:The cerebrospinal fluid (CSF) concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) as well as their ratios and correlations were analyzed in relation to the season of birth. The sample consisted of 241 drug-free patients par...

journal_title：Neuropsychobiology

authors： Chotai J,Asberg M

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The characterization of an individual's hypothalamic-pituitary-adrenal axis stress response is a main research topic in neuropsychobiology since alterations have been causally linked to several disease states. Over the last years, several studies focused on the identification of sources of inter- and intrain...

journal_title：Neuropsychobiology

authors： Kudielka BM,Fischer JE,Metzenthin P,Helfricht S,Preckel D,von Känel R

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Previous evidence suggested the possible association of FK506 binding protein 5 (FKBP5) gene variants in bipolar disorder (BPD). OBJECTIVE:Given the need of refinement of the findings obtained in large but poorly phenotyped samples, this study investigated the possible role of variants within FKBP5 in a sma...

journal_title：Neuropsychobiology

authors： Calabrò M,Crisafulli C,Di Nicola M,Colombo R,Janiri L,Serretti A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The polymorphisms of serotonergic genes (5-HTTLPR and HTR1A rs6295) and separation life events have been studied to find an association with panic disorder, respectively. However, there are no studies that have yet evaluated the interaction effect between serotonergic genes and separation life events for pan...

journal_title：Neuropsychobiology

authors： Choe AY,Kim B,Lee KS,Lee JE,Lee JY,Choi TK,Lee SH

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Memory processes, as reflected by 'old/new' effects of event-related potentials (ERPs), have been shown to be impaired in depressed patients. This variability might be partly explained by biological factors. S100B is a glial calcium-binding protein with neuroplastic properties; S100B serum levels have been sh...

journal_title：Neuropsychobiology

authors： Zhang Y,Rothermundt M,Peters M,Wiesmann M,Hoy L,Arolt V,Emrich HM,Dietrich DE

更新日期：2009-01-01 00:00:00

abstract：:In the present study all available young social alcohol abusers in the capital of Iceland are compared with a control group matched for age and intellectual level. Certain behaviour and social characteristics were found to occur more often during childhood among the abusers. Boys showing these characteristics should b...

journal_title：Neuropsychobiology

authors： Helgason T,Asmundsson G

更新日期：1975-01-01 00:00:00

abstract：:The effects of two benzodiazepines (alprazolam and bromazepam) on performance and event-related brain potentials (ERPs) in visual search and verbal recognition memory paradigms were tested in a placebo-controlled double-blind paradigm employing 12 young healthy subjects. Both drugs exerted similar effects on performan...

journal_title：Neuropsychobiology

authors： Münte TF,Gehde E,Johannes S,Seewald M,Heinze HJ

更新日期：1996-01-01 00:00:00

abstract：:The medical histories of 600 psychotic and 369 nonpsychotic subjects were examined for the occurrence of rheumatic chorea. There was significantly more rheumatic chorea in the histories of psychotic patients than in nonpsychotics (p less than 0.01, chi-square). Neuropathological associations are discussed. ...

journal_title：Neuropsychobiology

authors： Wilcox JA,Nasrallah HA

更新日期：1986-01-01 00:00:00

abstract：:This study was conducted to elucidate the effects of electroconvulsive therapy (ECT) on frontal white matter in late-life depressed patients. Diffusion tensor imaging was performed on 8 late-life depressed patients and 12 healthy age-matched controls. The patients were scanned before and after a course of ECT. Fractio...

journal_title：Neuropsychobiology

authors： Nobuhara K,Okugawa G,Minami T,Takase K,Yoshida T,Yagyu T,Tajika A,Sugimoto T,Tamagaki C,Ikeda K,Sawada S,Kinoshita T

更新日期：2004-01-01 00:00:00

abstract：:Two preliminary studies have indicated a variation in season of birth in severely language-disordered children. In the current study, the season of birth in 472 Danish children with language disorder born between 1958 and 1976 was compared with the season of birth of all Danish live-born children in the same period. F...

journal_title：Neuropsychobiology

authors： Hauschild KM,Mouridsen SE,Nielsen S

更新日期：2005-01-01 00:00:00

abstract：:93 cases of reactive depression have been followed up in order to investigate the long-term course of illness. By independent classification of reactive and endogenous depressions the authors agreed on diagnosis for 94%. Ten subgroups of reactive depressions are illustrated by case histories. It is of practical import...

journal_title：Neuropsychobiology

authors： Refsum HE,Astrup C

更新日期：1980-01-01 00:00:00

abstract：:The relationship between clinical effect of imipramine (IP) in 39 depressed patients and biochemical distinction, serum drug levels, and diagnostic classification was investigated retrospectively. Based on pretreatment plasma ratios of tryptophan and tyrosine to competing amino acids, which reflect the availability of...

journal_title：Neuropsychobiology

authors： Møller SE,Reisby N,Elley J,Krautwald O,Ortmann J,Larsen OB

更新日期：1985-01-01 00:00:00

abstract：:Several antipsychotics and antidepressants have been associated with electrocardiogram alterations, the most clinically relevant of which is the heart rate-corrected QT interval (QTc) prolongation, a risk factor for sudden cardiac death. Genetic variants influence drug-induced QTc prolongation and can provide valuable...

journal_title：Neuropsychobiology

authors： Corponi F,Fabbri C,Boriani G,Diemberger I,Albani D,Forloni G,Serretti A

更新日期：2019-01-01 00:00:00

abstract：:Saliva cortisol was measured at 11 p.m. in a sample of 74 psychiatric inpatients composed of 24 primary endogenous depressives, 40 secondary depressives and 20 nondepressives (DSM III and Saint-Louis criteria). Primary depressives had significantly higher 11 p.m. saliva cortisol levels than nondepressives (p less than...

journal_title：Neuropsychobiology

authors： Guéchot J,Lépine JP,Cohen C,Fiet J,Lempérière T,Dreux C

更新日期：1987-01-01 00:00:00

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for many neurotransmitter receptors. Among the adverse effects of clozapine, urinary incontinence is commonly found and is suggested to be caused by alpha-adrenergic blockade. We tested the hypothesis that clozapine-induced urinary incontinence is...

journal_title：Neuropsychobiology

authors： Hsu JW,Wang YC,Lin CC,Bai YM,Chen JY,Chiu HJ,Tsai SJ,Hong CJ

更新日期：2000-01-01 00:00:00

abstract：:The search for specific predepressive personality factors has a long tradition in psychiatry. Studies in which assessments were made prospectively, before the onset of a first-ever episode of the illness, are, however, rare. In the present report from the Lundby Study we have investigated premorbid, mainly personality...

journal_title：Neuropsychobiology

authors： Rorsman B,Gräsbeck A,Hagnell O,Isberg PE,Otterbeck L

更新日期：1993-01-01 00:00:00