Altered frontal and temporal brain function during olfactory stimulation in adult attention-deficit/hyperactivity disorder.

abstract：BACKGROUND:The characterization of an individual's hypothalamic-pituitary-adrenal axis stress response is a main research topic in neuropsychobiology since alterations have been causally linked to several disease states. Over the last years, several studies focused on the identification of sources of inter- and intrain...

journal_title：Neuropsychobiology

authors： Kudielka BM,Fischer JE,Metzenthin P,Helfricht S,Preckel D,von Känel R

更新日期：2007-01-01 00:00:00

abstract：:The popular recreational drug, (+/-)3, 4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') is a potent and selective brain serotonin (5-HT) neurotoxin in animals. MDMA-induced 5-HT neurotoxicity can be demonstrated using a variety of neurochemical, neuroanatomical and, more recently, functional measures of 5-HT neurons....

journal_title：Neuropsychobiology

authors： Ricaurte GA,Yuan J,McCann UD

更新日期：2000-01-01 00:00:00

abstract：:Morningness-eveningness preference by the self-rated Morningness-Eveningness Questionnaire (MEQ) has earlier been shown to be associated with the subjects' season of birth. Here, we obtain this result for a new sample of 2,125 university students and for the sample obtained by pooling the data with the earlier study, ...

journal_title：Neuropsychobiology

authors： Natale V,Adan A,Chotai J

更新日期：2002-01-01 00:00:00

abstract：:Previously, we performed an MRI study that revealed smaller volumes of the subregions of the cerebellar vermis in men and women with chronic schizophrenia. An issue that arose from that study was whether similar structural changes in the cerebellum are found in patients with first-episode schizophrenia. In the present...

journal_title：Neuropsychobiology

authors： Okugawa G,Nobuhara K,Takase K,Kinoshita T

更新日期：2007-01-01 00:00:00

abstract：:There is evidence that serotonin and norepinephrine are in some way involved in the pathophysiology of anxiety disorders. Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 46 patients with generalized anxiety di...

journal_title：Neuropsychobiology

authors： Garvey MJ,Noyes R Jr,Woodman C,Laukes C

更新日期：1995-01-01 00:00:00

abstract：:Administration of progesterone produces sleep EEG patterns that resemble those of agonistic modulators at the GABAA receptor. Previous studies evaluating the effects of an oral progesterone administration on attention performance in females pointed to putative sedative effects of progesterone at high dosages. However,...

journal_title：Neuropsychobiology

authors： Grön G,Friess E,Herpers M,Rupprecht R

更新日期：1997-01-01 00:00:00

abstract：:This study was conducted to elucidate the effects of electroconvulsive therapy (ECT) on frontal white matter in late-life depressed patients. Diffusion tensor imaging was performed on 8 late-life depressed patients and 12 healthy age-matched controls. The patients were scanned before and after a course of ECT. Fractio...

journal_title：Neuropsychobiology

authors： Nobuhara K,Okugawa G,Minami T,Takase K,Yoshida T,Yagyu T,Tajika A,Sugimoto T,Tamagaki C,Ikeda K,Sawada S,Kinoshita T

更新日期：2004-01-01 00:00:00

abstract：:Little information exists on the concentrations of recent antidepressants and their metabolites in cerebrospinal fluid (CSF). Using a stereoselective method, we measured plasma and CSF levels of mirtazapine (MIR), N-demethylmirtazapine and 8-OH-MIR in 3 depressed patients treated with racemic MIR (45 mg/day) for 4 wee...

journal_title：Neuropsychobiology

authors： Baumann P,Jonzier-Perey M,Paus E,Nikisch G

更新日期：2006-01-01 00:00:00

abstract：:REM sleep behavior disorder (RBD) is so far a possibly underestimated yet well-described sleep disorder. Its major impact is the vigorous sleep behavior that often results in injuries to the patient himself or to people sleeping nearby. We treated a 64-year-old male with a clinically and polysomnographically confirmed...

journal_title：Neuropsychobiology

authors： Kunz D,Bes F

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Considerable evidence suggests that variation of the serotonin-transporter-linked promoter region (5- HTTLPR) is associated with anxiety-related traits. Academic outcomes are also more closely related to trait anxiety. This preliminary study aimed to explore the association between academic performance and l...

journal_title：Neuropsychobiology

authors： Calapoğlu M,Sahin-Calapoğlu N,Karaçöp A,Soyöz M,Elyıldırım UY,Avşaroğlu S

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:In general, humans tend to discount the value of delayed reward. An increase in the rate of discounting leads to an inability to select a delayed reward over a smaller immediate reward (reward-delay impulsivity). Although deficits in the serotonergic system are implicated in this reward-delay impulsivit...

journal_title：Neuropsychobiology

authors： Demoto Y,Okada G,Okamoto Y,Kunisato Y,Aoyama S,Onoda K,Munakata A,Nomura M,Tanaka SC,Schweighofer N,Doya K,Yamawaki S

更新日期：2012-01-01 00:00:00

abstract：:In the present study, single-unit extracellular recording was used in male Wistar rats to compare the effects of a single dose (acute treatment) and a 21-day regimen (long-term treatment) with clomipramine (2.5 mg/kg) and fluoxetine (1.0 mg/kg) on the spontaneous firing rate of nucleus accumbens (NAcc) neurons connect...

journal_title：Neuropsychobiology

authors： Rodríguez-Landa JF,Contreras CM,Gutiérrez-García AG,Bernal-Morales B

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:There is some evidence that repetitive transcranial magnetic stimulation (rTMS) is an effective method of treating patients suffering from obsessive-compulsive disorder (OCD). Here, we tested the hypothesis that rTMS has a positive impact both on symptom severity and cognitive performance in such patients. Sp...

journal_title：Neuropsychobiology

authors： Jahangard L,Haghighi M,Shyayganfard M,Ahmadpanah M,Sadeghi Bahmani D,Bajoghli H,Holsboer-Trachsler E,Brand S

更新日期：2016-01-01 00:00:00

abstract：:Motor impairments of psychiatric patients can be assessed with digital recordings of handwriting tasks. The investigation of patients with bipolar affective disorders differentiates intraindividual changes related to the patient's fluctuating affective states. An unmedicated 67-year-old male with 48-hour bipolar ultra...

journal_title：Neuropsychobiology

authors： Tigges P,Juckel G,Schröter A,Möller HJ,Hegerl U

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Lithium augmentation is a first-line strategy for depressed patients resistant to antidepressive therapy, but little is known about patients' subsequent long-term course or outcome predictors. We investigated long-term outcomes of unipolar depressed patients who had participated in a study on the effects of ...

journal_title：Neuropsychobiology

authors： Adli M,Bschor T,Bauer M,Lucka C,Lewitzka U,Ising M,Uhr M,Mueller-Oerlinghausen B,Baethge C

更新日期：2009-01-01 00:00:00

abstract：:Apomorphine, a dopamine receptor agonist (given in a dose of 0.75 mg s.c.), was administered to 8 healthy volunteers; electroencephalograph (EEG) and event-related potential (ERP) mapping were performed before dosing and 0.5, 1.5 and 2.5 h after dosing. Apomorphine caused an overall increase in beta activity at time 0...

journal_title：Neuropsychobiology

authors： Luthringer R,Rinaudo G,Toussaint M,Bailey P,Muller G,Muzet A,Macher J

更新日期：1999-01-01 00:00:00

abstract：:We present a randomized double-blind study on the efficacy of caroverine in the treatment of alcohol withdrawal symptoms. The group B Ca2+ channel blocking agent caroverine was tested against meprobamate in inpatient treatment of alcohol withdrawal. Patients of both groups were similar in age, weight, duration of drin...

journal_title：Neuropsychobiology

authors： Koppi S,Eberhardt G,Haller R,König P

更新日期：1987-01-01 00:00:00

abstract：:46 severely depressed inpatients received 10-hour intravenous infusions supplying a dose of 720 mg dibenzepin daily on 2 or some cases 3 successive days. The patients were kept under close psychiatric surveillance and their cardiovascular function was carefully monitored. The shorter infusions were as effective as inf...

journal_title：Neuropsychobiology

authors： Gastpar M,Cornu F,Faessler J,Haefliger A,Keller H,von Lerber W,Pagan J,Rem J

更新日期：1984-01-01 00:00:00

abstract：:Marked hostility toward relatives, therapists and friends is very frequently observed in anorexia nervosa (AN) as expression of outward-directed aggressiveness which interferes with the therapeutic programs of the patients. With the purpose to investigate this aspect of the disorder and its biological background, we s...

journal_title：Neuropsychobiology

authors： Brambilla F,Bellodi L,Arancio C,Limonta D,Ferrari E,Solerte B

更新日期：2001-01-01 00:00:00

abstract：:Possible age effects on binding of [(3)H]lysergic acid diethylamide ([(3)H]LSD) to serotonin 5-HT(2A) receptors and of [(3)H]paroxetine to serotonin uptake sites were studied in platelets from healthy children (11-12 years of age), adolescents (16-17 years of age) and adults. Significant overall age effects were found...

journal_title：Neuropsychobiology

authors： Sigurdh J,Spigset O,Allard P,Mjörndal T,Hägglöf B

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND/AIMS:Previous functional neuroimaging studies have reported that patients with schizophrenia show reduced prefrontal activation during cognitive tasks whereas patients with schizotypal personality disorder (SPD) show preserved or even increased right prefrontal activation, compared to healthy controls; on th...

journal_title：Neuropsychobiology

authors： Hori H,Nagamine M,Soshi T,Okabe S,Kim Y,Kunugi H

更新日期：2008-01-01 00:00:00

abstract：:Renal lithium clearance and the serum lithium levels following a single oral loading dose of lithium were used as measures to predict lithium dose requirement during long-term maintenance at 3 different psychiatric centers in North America. Saliva lithium values were also investigated at one of the centers. The correl...

journal_title：Neuropsychobiology

authors： Tyrer SP,Grof P,Kalvar M,Shopsin B

更新日期：1981-01-01 00:00:00

abstract：:Personality traits were assessed in a series of 148 patients classified according to Winokur into depression pure disease (DPD), depression spectrum disease (DSD) and sporadic depression (SD) with the addition of a fourth group: family history positive-others (FH + .O) comprised of patients with psychiatric disorders ...

journal_title：Neuropsychobiology

authors： Perris C,Eisemann M,Ericsson U,von Knorring L,Perris H

更新日期：1983-01-01 00:00:00

abstract：:In the past, some researchers found increased cortisol and prolactin responses to the administration of fenfluramine in major-depressed patients. It was believed that the fenfluramine test could prove to constitute another challenge probe to reflect the central serotonergic function. The present study was conducted in...

journal_title：Neuropsychobiology

authors： Maes M,Jacobs MP,Suy E,Minner B,Raus J

更新日期：1989-01-01 00:00:00

abstract：:To clarify the role of the serotonergic system in limbic and thalamic epileptic activity, we examined the effects of 5-hydroxytryptophan (5-HTP, 20 and 40 mg/kg) on fully kindled seizures from the hippocampus and lateral geniculate nucleus. The intraperitoneal administration of 20 mg/kg 5-HTP exerted no anticonvulsant...

journal_title：Neuropsychobiology

authors： Wada Y,Hasegawa H,Nakamura M,Yamaguchi N

更新日期：1992-01-01 00:00:00

abstract：:A considerable proportion of chronic non-organic pain patients suffer from insomnia, and alpha sleep has been suggested to be specifically associated with fibromyalgia. However, the clinical significance of those symptoms is not clear. This study was carried out to investigate this question. Twenty-six middle-aged, no...

journal_title：Neuropsychobiology

authors： Schneider-Helmert D,Whitehouse I,Kumar A,Lijzenga C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Limbic circuitry, especially the anterior cingulate gyrus, has been implicated in the pathophysiology and cognitive changes of schizophrenia. Previous diffusion tensor imaging studies have demonstrated that the integrity of the anterior cingulum (AC) is abnormal in schizophrenia. However, the relationship be...

journal_title：Neuropsychobiology

authors： Hayakawa YK,Kirino E,Shimoji K,Kamagata K,Hori M,Ito K,Kunimatsu A,Abe O,Ohtomo K,Aoki S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Time of onset of antipsychotic action is still a debated matter. We aimed to replicate and extend previous findings that early response can predict subsequent non-response. METHODS:86 acutely psychotic patients treated with haloperidol were studied. RESULTS:A PANSS reduction ≤16% at 1 week predict...

journal_title：Neuropsychobiology

authors： Giegling I,Porcelli S,Balzarro B,Andrisano C,Schäfer M,Möller HJ,Rujescu D,Serretti A

更新日期：2012-01-01 00:00:00

abstract：:The region coding human leukocyte antigen (HLA) on chromosome 6q21 was shown to be associated with both the vulnerability to schizophrenia and presence of eye movement disturbances (EMD). The aim of this preliminary study was to investigate how individual class I and II HLA antigens in schizophrenic patients may be re...

journal_title：Neuropsychobiology

authors： Bogacki PA,Borkowska A,Wojtanowska-Bogacka M,Rybakowski JK

更新日期：2005-01-01 00:00:00

abstract：:The analysis of the results obtained in different tests--sleep studies, cortical and hippocampal EEG activity, PGO-R spikes--in rats or in cats allows the characterization of different classes of drugs and to establish the relative efficacy of psychoactive drugs in these models. Moreover, the sequential spectral analy...

journal_title：Neuropsychobiology

authors： Depoortere H,Decobert M,Honoré L

更新日期：1983-01-01 00:00:00