The association of urinary 5-hydroxyindoleacetic acid and vanillylmandelic acid in patients with generalized anxiety.

Abstract:

:There is evidence that serotonin and norepinephrine are in some way involved in the pathophysiology of anxiety disorders. Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 46 patients with generalized anxiety disorder. There was a significant association between urinary levels of 5-HIAA and VMA: r = 0.79; p = 0.0001. Possible implications of this finding are discussed.

journal_name

Neuropsychobiology

journal_title

Neuropsychobiology

authors

Garvey MJ,Noyes R Jr,Woodman C,Laukes C

doi

10.1159/000119165

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

6-9

issue

1

eissn

0302-282X

issn

1423-0224

journal_volume

31

pub_type

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