Drug effects on the EEG of various species of laboratory animals.

abstract：:This study aimed to investigate the binding affinity of [3H]GABA and [3H]beta-alanine to GABA transporters GAT-1 and GAT-3 in the human dorsolateral prefrontal cortex (Brodmanns' area 9) in schizophrenia. Using post mortem tissue from individuals diagnosed with schizophrenia (n=6) and control subjects (n=6), the densi...

journal_title：Neuropsychobiology

authors： Schleimer SB,Hinton T,Dixon G,Johnston GA

更新日期：2004-01-01 00:00:00

abstract：:In obstructive sleep apnea patients, who intermittently stop breathing at night for some seconds, functions of vigilance and attention seem to be impaired. The aim of our study was to investigate if nocturnal hypoxia as one possible detrimental factor is associated with the degree of modality shift effect expressing a...

journal_title：Neuropsychobiology

authors： Gresele C,Hein H,Eggert F

更新日期：1998-01-01 00:00:00

abstract：:Isolation causes important changes in the behavioral reactivity of rats to environmental stimuli. These changes include deficit in sensorimotor gating and altered fear-like responses to aversive stimuli. Measures of ultrasound vocalizations at 20-22 kHz when rats are exposed to threatening conditions, such as novelty,...

journal_title：Neuropsychobiology

authors： Nunes Mamede Rosa ML,Nobre MJ,Ribeiro Oliveira A,Brandão ML

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Schizophrenia, a common neurological disorder appearing in the late teens or early adulthood, is characterized by disorganized thinking, behaviour, and perception of emotions. Aberrant N-methyl-D-aspartate (NMDA) receptor-mediated synaptic plasticity is a major pathological event here due to dysfunction of do...

journal_title：Neuropsychobiology

authors： Janardhanan A,Sadanand A,Vanisree AJ

更新日期：2016-01-01 00:00:00

abstract：:The effects of zolpidem or zaleplon on sleep architecture, respiratory patterns and performance were assessed at a simulated altitude of 4,000 m. Twelve male healthy subjects spent 4 nights in a decompression chamber, 1 at sea level (baseline), 3 at 4,000 m to test zolpidem (10 mg), zaleplon (10 mg) and placebo, given...

journal_title：Neuropsychobiology

authors： Beaumont M,Batéjat D,Coste O,Van Beers P,Colas A,Clère JM,Piérard C

更新日期：2004-01-01 00:00:00

abstract：:Acute quantitative electroencephalographic effects of cigarette smoking were examined in 15 smokers within a repeated-measures design which assessed changes in power-spectral estimates following acute pre-treatment with placebo, a dose (20 mg) of mecamylamine, a dose (0.6 mg) of scopolamine and a combined dose of meca...

journal_title：Neuropsychobiology

authors： Knott VJ,Harr A,Ilivitsky V,Mahoney C

更新日期：1998-01-01 00:00:00

abstract：:Like the industry, the medical profession takes now an interest in quality assurance programs. In the field of psychiatry, the quality assessment of antidepressive drug prescriptions is an ideal target. A brief review of previous studies reveals a high prevalence of the use of psychotropes among the general population...

journal_title：Neuropsychobiology

authors： Wilmotte J

更新日期：1989-01-01 00:00:00

abstract：:In contrast to the single-channel dimensional complexity, the global dimensional complexity is calculated from a multichannel EEG. The intention with the method is to measure the spatial distribution of information processing in the brain. The method seems to be of interest in psychopharmacological research, but the i...

journal_title：Neuropsychobiology

authors： Matousek M,Wackermann J,Palus M,Berankova A,Albrecht V,Dvorak I

更新日期：1995-01-01 00:00:00

abstract：:Previously, we performed an MRI study that revealed smaller volumes of the subregions of the cerebellar vermis in men and women with chronic schizophrenia. An issue that arose from that study was whether similar structural changes in the cerebellum are found in patients with first-episode schizophrenia. In the present...

journal_title：Neuropsychobiology

authors： Okugawa G,Nobuhara K,Takase K,Kinoshita T

更新日期：2007-01-01 00:00:00

abstract：:In 63 depressed patients, the associations between severity of depression, psychomotor retardation, assessed by the Bech-Rafaelsen Melancholia Scale, and EEG spectral analysis were examined. Slow EEG activity (theta 2/alpha 1 bands) was positively and fast activity (alpha 3/beta bands) negatively correlated with the o...

journal_title：Neuropsychobiology

authors： Nieber D,Schlegel S

更新日期：1992-01-01 00:00:00

abstract：:Recent studies have suggested that synaptic abnormalities may be part of the pathophysiology of schizophrenia. SNAP-25 (synaptosomal-associated protein of 25 kD) is one of the synaptic proteins responsible for presynaptic neurotransmission, axonal elongation and synaptogenesis. Genetic variation in the 5'-upstream reg...

journal_title：Neuropsychobiology

authors： Tachikawa H,Harada S,Kawanishi Y,Okubo T,Suzuki T

更新日期：2001-01-01 00:00:00

abstract：:The cerebrospinal fluid (CSF) concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) as well as their ratios and correlations were analyzed in relation to the season of birth. The sample consisted of 241 drug-free patients par...

journal_title：Neuropsychobiology

authors： Chotai J,Asberg M

更新日期：1999-01-01 00:00:00

abstract：:Nitric oxide (NO) has been implicated to play a role in the pathogenesis of depressive disorders. Adrenomedullin (AM) induces vasorelaxation by activating adenylate cyclase and also by stimulating the release of NO. AM immune reactivity is present in the brain, consistent with a role as neurotransmitter. Therefore, it...

journal_title：Neuropsychobiology

authors： Savaş HA,Herken H,Yürekli M,Uz E,Tutkun H,Zoroğlu SS,Ozen ME,Cengiz B,Akyol O

更新日期：2002-01-01 00:00:00

abstract：:The prevalence of 3,4-methylenedioxymethamphetamine (MDMA) use has increased globally and the pattern of consumption has changed considerably. Previously, a subculture of MDMA users was fairly restricted to the dance club scene. More recently, use has spread outside of this subculture and now many users consume MDMA f...

journal_title：Neuropsychobiology

authors： Schenk S

更新日期：2009-01-01 00:00:00

abstract：:Memory loss and severe cognitive deficits in Alzheimer patients are supposed to be related to a reduction of acetylcholine as well as to central nervous deactivation. For the investigation of cholinergic deficits and deactivation, we used computer-assisted pupillometry. Cholinergic deficits caused by a particularly se...

journal_title：Neuropsychobiology

authors： Grünberger J,Linzmayer L,Walter H,Rainer M,Masching A,Pezawas L,Saletu-Zyhlarz G,Stöhr H,Grünberger M

更新日期：1999-01-01 00:00:00

abstract：:To clarify the role of the serotonergic system in limbic and thalamic epileptic activity, we examined the effects of 5-hydroxytryptophan (5-HTP, 20 and 40 mg/kg) on fully kindled seizures from the hippocampus and lateral geniculate nucleus. The intraperitoneal administration of 20 mg/kg 5-HTP exerted no anticonvulsant...

journal_title：Neuropsychobiology

authors： Wada Y,Hasegawa H,Nakamura M,Yamaguchi N

更新日期：1992-01-01 00:00:00

abstract：:Quantitative assessment of regional cerebral blood flow (rCBF) was performed in a 22-year-old man with intractable temporal lobe epilepsy on long-term high-dose phenytoin (PHT) therapy, using single photon emission computed tomography (SPECT) with N-isopropyl-(iodine-123)-p-iodoamphetamine. In all the SPECT scans repe...

journal_title：Neuropsychobiology

authors： Jibiki I,Kido H,Yamaguchi N,Matsuda H,Hisada K

更新日期：1993-01-01 00:00:00

abstract：:46 severely depressed inpatients received 10-hour intravenous infusions supplying a dose of 720 mg dibenzepin daily on 2 or some cases 3 successive days. The patients were kept under close psychiatric surveillance and their cardiovascular function was carefully monitored. The shorter infusions were as effective as inf...

journal_title：Neuropsychobiology

authors： Gastpar M,Cornu F,Faessler J,Haefliger A,Keller H,von Lerber W,Pagan J,Rem J

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP), a marker of underlying low-grade inflammation, has been associated with the pathophysiology of bipolar disorder. Additionally, bipolar disorder may be accompanied by functional or structural cerebral alterations. We attempted to discover whether serum high-sensitivity CRP (hs-CRP) le...

journal_title：Neuropsychobiology

authors： Chung KH,Huang SH,Wu JY,Chen PH,Hsu JL,Tsai SY

更新日期：2013-01-01 00:00:00

abstract：:The acute effects of alcohol (0.7 g/kg) on visual signal detection performance and critical flicker fusion frequency (CFF) of normal volunteers were investigated using a signal detection theory analysis. When signal probability was low, alcohol affected the stimulus sensitivity and the reaction times of hits. Under a ...

journal_title：Neuropsychobiology

authors： Jansen AA,de Gier JJ,Slangen JL

更新日期：1985-01-01 00:00:00

abstract：:The authors recorded contingent negative variation (CNV) in a group of subjects affected by presenile dementia, at the onset of the symptoms, with a slight degree of intellectual deterioration. Recordings were carried out in rest basal conditions and upon administration of an insignificant distracting stimulus. Result...

journal_title：Neuropsychobiology

authors： Rizzo PA,Albani G,Cicardi C,Spadaro M,Morocutti C

更新日期：1984-01-01 00:00:00

abstract：:The author contended opposite pharmacological effects resulting from lithium and amphetamine. Three groups, each one consisting of four rats, were put on chronic lithium condition to measure its effects on amphetamine hyperactivity. This condition was effected after appropriate handling and saline control periods and ...

journal_title：Neuropsychobiology

authors： Flemenbaum A

更新日期：1975-01-01 00:00:00

abstract：:Urinary 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in 53 depressed women were compared to current suicidal thoughts or activity. Comparisons were also made between MHPG and past suicide attempts, number of past attempts, and seriousness of the worst attempt. There was a weak trend for current but not past suicidali...

journal_title：Neuropsychobiology

authors： Garvey MJ,Hollon SD,Tuason VB

更新日期：1994-01-01 00:00:00

abstract：:Cerebrospinal fluid (CSF) homovanillic acid, 5-hydroxyindoleacetic acid, 3-methoxy-4-hydroxyphenylglycol, and somatostatin and beta-endorphin levels were measured in 12 patients with panic disorder before and after 7 months of treatment with alprazolam or imipramine. The concentrations of CSF monoamine metabolites and...

journal_title：Neuropsychobiology

authors： Lepola U,Jolkkonen J,Rimón R,Riekkinen P

更新日期：1989-01-01 00:00:00

abstract：:Schizophrenia is a heterogeneous and multidimensional disorder. The different syndromes or dimensions of this disorder represent distinct pathophysiological processes. Evidence is growing that each of the composite syndromes or dimensions of this disorder is associated with specific validators. This article reviewed n...

journal_title：Neuropsychobiology

authors： Aderibigbe YA,Gureje O

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:There is evidence that the nicotinic alpha7-acetylcholine receptor (alpha7-AChR) is involved in the pathophysiology of schizophrenia. Several neurotransmitter receptors, including alpha7-AChR, have been demonstrated on peripheral blood lymphocytes (PBL) and it has been suggested that these peripheral recepto...

journal_title：Neuropsychobiology

authors： Perl O,Strous RD,Dranikov A,Chen R,Fuchs S

更新日期：2006-01-01 00:00:00

abstract：:Volunteers who develop a cold following virus challenge were significantly slower on choice reaction time tasks than those with no illness. This effect was still observed after the clinical symptoms had gone. In contrast to this, influenza illnesses only impaired performance in tasks in which subjects were uncertain w...

journal_title：Neuropsychobiology

authors： Smith AP,Tyrrell DA,al-Nakib W,Barrow PG,Higgins PG,Leekam S,Trickett S

更新日期：1989-01-01 00:00:00

abstract：:We have previously shown that the tilt aftereffect (TAE) appears to respond to changes in central dopaminergic function. In this study, the TAE was investigated during the preovulatory and the premenstrual phases of the menstrual cycle. Results in the preovulatory phase mimicked those previously found associated with ...

journal_title：Neuropsychobiology

authors： Symons E,Calvert JE,Snelgar RS,Harris JP

更新日期：1990-01-01 00:00:00

abstract：:Genetic polymorphism of the serotonin 5-HT(2A) receptor seems to be associated with therapeutic response to selective serotonin reuptake inhibitors (SSRIs). The present study investigated whether a novel -1438G/A polymorphism in the promoter region of the 5-HT(2A )receptor gene is associated with therapeutic response ...

journal_title：Neuropsychobiology

authors： Sato K,Yoshida K,Takahashi H,Ito K,Kamata M,Higuchi H,Shimizu T,Itoh K,Inoue K,Tezuka T,Suzuki T,Ohkubo T,Sugawara K,Otani K

更新日期：2002-01-01 00:00:00

abstract：:The growing number of studies examining the relationship between suicide and lipid metabolism are based upon studies suggesting that cholesterol-lowering procedures may increase the risk of death due to suicide or impulsive-aggressive behavior. Leptin seems to be strongly associated with lipid metabolism. In the prese...

journal_title：Neuropsychobiology

authors： Atmaca M,Kuloglu M,Tezcan E,Ustundag B,Gecici O,Firidin B

更新日期：2002-01-01 00:00:00