Platelet-associated antibodies mediate protective autoimmune response in schizophrenia.

Abstract:

:The peripheral blood platelets of schizophrenic patients were isolated, and the level of the platelet-associated antibodies (SPAA) was correlated with the rating scores of discrete schizophrenic symptom clusters evaluated with the Brief Psychiatric Rating Scale. Irrespective of medication and gender, symptom-dependent correlations were established between the SPAA levels and the relevant psychometric scores. The results indicate a heterogeneous origin of schizophrenia and imply the involvement of an autoimmune arm as a predominantly protective immune response.

journal_name

Neuropsychobiology

journal_title

Neuropsychobiology

authors

Sinyakov MS,Kessler B,Karp L,Weizman A,Kessler AR

doi

10.1159/000071828

keywords:

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

41-6

issue

1

eissn

0302-282X

issn

1423-0224

pii

71828

journal_volume

48

pub_type

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