Plasma 3,4-dihydroxyphenylethyleneglycol and therapeutic response to maprotiline and indalpine in major depression.

abstract：:There is increasing evidence for an influence of directed attention on prepulse inhibition (PPI) of the acoustic startle reflex. However, the existing paradigms for the assessment of this effect have methodological problems and pitfalls. In particular, most previous studies used a paradigm which directed the attention...

journal_title：Neuropsychobiology

authors： Heekeren K,Meincke U,Geyer MA,Gouzoulis-Mayfrank E

更新日期：2004-01-01 00:00:00

abstract：:Administration of progesterone produces sleep EEG patterns that resemble those of agonistic modulators at the GABAA receptor. Previous studies evaluating the effects of an oral progesterone administration on attention performance in females pointed to putative sedative effects of progesterone at high dosages. However,...

journal_title：Neuropsychobiology

authors： Grön G,Friess E,Herpers M,Rupprecht R

更新日期：1997-01-01 00:00:00

abstract：:Symptoms of anxiety suggest autonomic dysfunction and most of the psychotropic agents used to treat anxiety and affective disorders have strong autonomic effects. This article describes the utility and importance of analysis of heart rate and blood pressure time series to study cardiac autonomic function in psychiatri...

journal_title：Neuropsychobiology

authors： Yeragani VK

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:We examined striatal dopamine transporter (DAT) binding in bipolar and unipolar depressed patients and compared these values to those obtained from healthy control subjects using the selective DAT radioligand [(99m)Tc]TRODAT-1 and single photon emission computed tomography imaging. We hypothesized that DAT le...

journal_title：Neuropsychobiology

authors： Amsterdam JD,Newberg AB

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Psychosis spectrum disorders, especially schizophrenia, have been linked to disturbed dopaminergic activity in the brain. Plasma homovanillic acid (pHVA) levels partly represent dopaminergic metabolism in the central nervous system. In the present study associations between (changes in) pHVA levels, symptom ...

journal_title：Neuropsychobiology

authors： van de Kerkhof NW,Fekkes D,van der Heijden FM,Egger JI,Verhoeven WM

更新日期：2015-01-01 00:00:00

abstract：:Six WHO Collaborating Centre took part in the study of the antithymic activity of blood sera of patients suffering from schizophrenia. Blood serum specimens from 118 schizophrenic patients and 62 mentally healthy donors were investigated. Statistically significant differences between schizophrenic patients and the con...

journal_title：Neuropsychobiology

authors： Koliaskina G,Tsutsulkovskaya M,Domashneva I,Maznina T,Kielholz P,Gastpar M,Bunney W,Rafaelsen O,Heltberg J,Coppen A,Hippius H,Hoecherl B,Vartanian F

更新日期：1980-01-01 00:00:00

abstract：:77 primary depressive in-patients aged 18-70 years (mean = 46/47 years) were assigned randomly to experimental and control groups and treated in double-blind conditions in ten centers. Butriptyline and amitriptyline were both administered with an identical increasing schedule, up to 150 mg daily in the first week and ...

journal_title：Neuropsychobiology

authors： Guelfi JD,Dreyfus JF,Delcros M,Pichot P

更新日期：1983-01-01 00:00:00

abstract：:All-night sleep of 5 healthy male subjects was scored on the basis of EEG (paper records), EMG and EOG into the stages of wakefulness, REM sleep and slow sleep stages 1-4 according to Rechtschaffen and Kales. Spectral analysis for 8 EEG channels was then performed and spectral parameters (total power and coherence for...

journal_title：Neuropsychobiology

authors： Molinari L,Dumermuth G,Lange B

更新日期：1984-01-01 00:00:00

abstract：:Isolation causes important changes in the behavioral reactivity of rats to environmental stimuli. These changes include deficit in sensorimotor gating and altered fear-like responses to aversive stimuli. Measures of ultrasound vocalizations at 20-22 kHz when rats are exposed to threatening conditions, such as novelty,...

journal_title：Neuropsychobiology

authors： Nunes Mamede Rosa ML,Nobre MJ,Ribeiro Oliveira A,Brandão ML

更新日期：2005-01-01 00:00:00

abstract：:Quantitative pharmaco-EEG has become a useful technique for determining pharmacodynamic parameters after CNS-active drug administration. Nevertheless, one of the most important problems faced by practitioners of pharmaco-EEG is the difficulty in evaluating drug-specific effects. In this article, a methodology for comp...

journal_title：Neuropsychobiology

authors： Dago KT,Luthringer R,Lengellé R,Rinaudo G,Macher JP

更新日期：1994-01-01 00:00:00

abstract：:The search for specific predepressive personality factors has a long tradition in psychiatry. Studies in which assessments were made prospectively, before the onset of a first-ever episode of the illness, are, however, rare. In the present report from the Lundby Study we have investigated premorbid, mainly personality...

journal_title：Neuropsychobiology

authors： Rorsman B,Gräsbeck A,Hagnell O,Isberg PE,Otterbeck L

更新日期：1993-01-01 00:00:00

abstract：:We have previously shown that the tilt aftereffect (TAE) appears to respond to changes in central dopaminergic function. In this study, the TAE was investigated during the preovulatory and the premenstrual phases of the menstrual cycle. Results in the preovulatory phase mimicked those previously found associated with ...

journal_title：Neuropsychobiology

authors： Symons E,Calvert JE,Snelgar RS,Harris JP

更新日期：1990-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled study the effect of nocturnal traffic noise and bedtime medication of a new benzodiazepine, OX-373, on objective and subjective sleep variables as well as on the quality of morning awakenings was investigated. 10 healthy subjects spent 17 nights in the sleep laboratory: 2 adaptati...

journal_title：Neuropsychobiology

authors： Saletu B,Grünberger J

更新日期：1981-01-01 00:00:00

abstract：:The popular recreational drug, (+/-)3, 4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') is a potent and selective brain serotonin (5-HT) neurotoxin in animals. MDMA-induced 5-HT neurotoxicity can be demonstrated using a variety of neurochemical, neuroanatomical and, more recently, functional measures of 5-HT neurons....

journal_title：Neuropsychobiology

authors： Ricaurte GA,Yuan J,McCann UD

更新日期：2000-01-01 00:00:00

abstract：:Serum dopamine-beta-hydroxylase (DBH) levels were assessed in 150 depressed patients of both sexes, with a mean age of 44.0 +/- 12.3 (SD) years. Patients were divided into unipolars (n = 46), bipolars (n = 25), neurotic-reactive (n = 46) and unspecified (n = 38) i.e., those who did not fit into any of the previous cat...

journal_title：Neuropsychobiology

authors： Eisemann M,Ericsson U,Von Knorring L,Perris C,Perris H,Ross S

更新日期：1983-01-01 00:00:00

abstract：:To clarify the circadian aspects of delayed sleep phase syndrome (DSPS) in 4 patients with DSPS, we recorded polysomnograms and rectal temperature before and after chronotherapy. The time interval (2.7 h) between sleep onset and rectal temperature minimum before chronotherapy was shorter than the time interval after c...

journal_title：Neuropsychobiology

authors： Ozaki N,Iwata T,Itoh A,Kogawa S,Ohta T,Okada T,Kasahara Y

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND/AIMS:Suicidal behavior (SB) in bipolar disorder (BD) is a complex multifactorial event resulting from an interaction of genetic, neurobiological and psychosocial factors. Recent studies identified new possible mechanisms, suggesting a role for sirtuins (SIRTs 1-7), a family of nicotinamide adenine dinucleoti...

journal_title：Neuropsychobiology

authors： Nivoli A,Porcelli S,Albani D,Forloni G,Fusco F,Colom F,Vieta E,Serretti A

更新日期：2016-01-01 00:00:00

abstract：:Cortisol has a modulatory influence on cognitive functions in humans. Both impairing and enhancing effects of cortisol administration have been shown for hippocampus-dependent declarative memory, and impairing effects have been shown for prefrontal-cortex-dependent working memory function. Given the high density of gl...

journal_title：Neuropsychobiology

authors： Kumsta R,Entringer S,Koper JW,van Rossum EF,Hellhammer DH,Wüst S

更新日期：2010-01-01 00:00:00

abstract：:No consensus has been obtained about blood electrolyte status, especially about magnesium, in affective disorders. This is mainly due to the lack of information about the distribution of the patients in clinical subgroups, sex, type of treatment and about the severity of their illnesses. Most of these studies concerne...

journal_title：Neuropsychobiology

authors： Widmer J,Bovier P,Karege F,Raffin Y,Hilleret H,Gaillard JM,Tissot R

更新日期：1992-01-01 00:00:00

abstract：:In the search for differential mechanisms underlying clozapine's superior antipsychotic efficacy, the purinergic system has been considered, since an antagonist of the adenosine receptor A(2A) was shown to block clozapine acute effects on c-fos expression in rat striatum. Further investigating the interaction of cloza...

journal_title：Neuropsychobiology

authors： Lara DR,Vianna MR,de Paris F,Quevedo J,Oses JP,Battastini AM,Sarkis JJ,Souza DO

更新日期：2001-01-01 00:00:00

abstract：:The medical histories of 600 psychotic and 369 nonpsychotic subjects were examined for the occurrence of rheumatic chorea. There was significantly more rheumatic chorea in the histories of psychotic patients than in nonpsychotics (p less than 0.01, chi-square). Neuropathological associations are discussed. ...

journal_title：Neuropsychobiology

authors： Wilcox JA,Nasrallah HA

更新日期：1986-01-01 00:00:00

abstract：:Despite being the most widely consumed psychoactive substance in the world, there is considerable confusion regarding the effects of caffeine. This study examined objective indices of performance, and self-reported mood, headache, and sleep in 36 healthy male and female habitual caffeine consumers exposed to a pattern...

journal_title：Neuropsychobiology

authors： James JE

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The present study investigated the effects of rapid tryptophan depletion (RTD), and the ensuing reduction of central nervous system levels of serotonin (5-HT), upon reactive aggression in patients with attention deficit/hyperactivity disorder (ADHD). Furthermore, it was asked whether the relation between 5-H...

journal_title：Neuropsychobiology

authors： Stadler C,Zepf FD,Demisch L,Schmitt M,Landgraf M,Poustka F

更新日期：2007-01-01 00:00:00

abstract：:To clarify the role of the serotonergic system in limbic and thalamic epileptic activity, we examined the effects of 5-hydroxytryptophan (5-HTP, 20 and 40 mg/kg) on fully kindled seizures from the hippocampus and lateral geniculate nucleus. The intraperitoneal administration of 20 mg/kg 5-HTP exerted no anticonvulsant...

journal_title：Neuropsychobiology

authors： Wada Y,Hasegawa H,Nakamura M,Yamaguchi N

更新日期：1992-01-01 00:00:00

abstract：:Eight patients with chronic obsessive-compulsive neurosis were subjected to trazodone, an antidepressant acting on the serotonergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement ha...

journal_title：Neuropsychobiology

authors： Prasad A

更新日期：1986-01-01 00:00:00

abstract：:Apomorphine, a dopamine receptor agonist (given in a dose of 0.75 mg s.c.), was administered to 8 healthy volunteers; electroencephalograph (EEG) and event-related potential (ERP) mapping were performed before dosing and 0.5, 1.5 and 2.5 h after dosing. Apomorphine caused an overall increase in beta activity at time 0...

journal_title：Neuropsychobiology

authors： Luthringer R,Rinaudo G,Toussaint M,Bailey P,Muller G,Muzet A,Macher J

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The failure to inhibit pleasurable but inappropriate urges is associated with frontal lobe pathology and has been suggested as a possible cause of pedophilic behavior. However, imaging and neuropsychological findings about frontal pathology in pedophilia are heterogeneous. In our study we therefore address i...

journal_title：Neuropsychobiology

authors： Habermeyer B,Esposito F,Händel N,Lemoine P,Kuhl HC,Klarhöfer M,Mager R,Mokros A,Dittmann V,Seifritz E,Graf M

更新日期：2013-01-01 00:00:00

abstract：:In the present study, single-unit extracellular recording was used in male Wistar rats to compare the effects of a single dose (acute treatment) and a 21-day regimen (long-term treatment) with clomipramine (2.5 mg/kg) and fluoxetine (1.0 mg/kg) on the spontaneous firing rate of nucleus accumbens (NAcc) neurons connect...

journal_title：Neuropsychobiology

authors： Rodríguez-Landa JF,Contreras CM,Gutiérrez-García AG,Bernal-Morales B

更新日期：2003-01-01 00:00:00

abstract：:Saliva cortisol was measured at 11 p.m. in a sample of 74 psychiatric inpatients composed of 24 primary endogenous depressives, 40 secondary depressives and 20 nondepressives (DSM III and Saint-Louis criteria). Primary depressives had significantly higher 11 p.m. saliva cortisol levels than nondepressives (p less than...

journal_title：Neuropsychobiology

authors： Guéchot J,Lépine JP,Cohen C,Fiet J,Lempérière T,Dreux C

更新日期：1987-01-01 00:00:00

abstract：:Diabetes mellitus can induce impairment in learning and memory. Cognitive and memory deficits are common in older adults and especially in those with diabetes. This is mainly because of hyperglycemia, oxidative stress, and vascular abnormalities. Coenzyme Q10 (CoQ10) can decrease oxidative stress, hyperglycemia, and i...

journal_title：Neuropsychobiology

authors： Monsef A,Shahidi S,Komaki A

更新日期：2019-01-01 00:00:00