Acute and chronic effects of caffeine on performance, mood, headache, and sleep.

Abstract:

:Despite being the most widely consumed psychoactive substance in the world, there is considerable confusion regarding the effects of caffeine. This study examined objective indices of performance, and self-reported mood, headache, and sleep in 36 healthy male and female habitual caffeine consumers exposed to a pattern of moderate intake. A double-blind placebo-controlled cross-over design with counterbalancing was employed in which all subjects participated in four experimental conditions involving the ingestion of placebo or caffeine 3 times daily for 6 days followed by a 7th (challenge) day of placebo or caffeine ingestion. No evidence was found that caffeine improved performance, either in the context of acute or habitual use. On the contrary, performance was found to be significantly impaired when caffeine was withdrawn abruptly following habitual use. Participants reported feeling more alert and less tired following acute ingestion of caffeine, but feeling less alert in conjunction with chronic exposure to the drug. In addition, caffeine withdrawal was associated with reported increases in frequency and severity of headache, and with reports of sleeping longer and more soundly.

journal_name

Neuropsychobiology

journal_title

Neuropsychobiology

authors

James JE

doi

10.1159/000026514

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

32-41

issue

1

eissn

0302-282X

issn

1423-0224

pii

nps38032

journal_volume

38

pub_type

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