Relationship between alcoholism and CYP2E1 C/D polymorphism.

abstract：:Somatosensory event-related potentials (SERP) were recorded in 30 chronic young schizophrenic patients and in 15 age-matched controls. Objective SERP parameters were latencies, amplitudes and the determination of areas of the cognitive components N1 and P3 by integration. Highly significantly reduced areas and prolong...

journal_title：Neuropsychobiology

authors： Böning J,Drechsler F,Neuhauser B

更新日期：1989-01-01 00:00:00

abstract：:A group of 27 patients with definite (n = 20) or probable (n = 7) RDC major depressive disorder underwent 2 sleep EEGs and 1 TRH test while in a drug-free depressive phase. A short mean REM latency (less than 60 min) identified 55.5% of major depressives while added use of blunted TSH responses (delta max. less than 5...

journal_title：Neuropsychobiology

authors： Pugnetti L,Scarone S,Brambilla F

更新日期：1987-01-01 00:00:00

abstract：:The soporific effect of the neuroactive steroid pregnanolone, a metabolite of progesterone, and its relationship with plasma concentrations was assessed in 18 young, healthy, male volunteers for 2 h after administration of a single dose of pregnanolone prepared in two different formulations. Sedation was measured as s...

journal_title：Neuropsychobiology

authors： Schulz H,Jobert M,Gee KW,Ashbrook DW

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Although differences in symptom profiles and outcome between depressive patients with an underlying major depressive disorder (MDD) and bipolar depression (BD) have been reported, studies with sequential short-interval assessments in a real-life inpatient setting are scarce. OBJECTIVES:To examine potential ...

journal_title：Neuropsychobiology

authors： Hebbrecht K,Stuivenga M,Birkenhäger T,van der Mast RC,Sabbe B,Giltay EJ

更新日期：2020-01-01 00:00:00

abstract：:Peripheral benzodiazepine receptors (PBR) have been identified in peripheral organs as well as in brain glial cells. PBR differ from central benzodiazepine receptors (CBR) in their lack of coupling to the gamma-aminobutyric acid receptors and the chloride ion channels. We investigated the effect of 21 days administrat...

journal_title：Neuropsychobiology

authors： Leschiner S,Weizman R,Shoukrun R,Veenman L,Gavish M

更新日期：2000-01-01 00:00:00

abstract：:Single, 50- and 100-mg oral doses of phenobarbital and a matching placebo were administered double-blind to 8 young, healthy male subjects. Multilead electroencephalographic (EEG) samples were recorded prior to, and at regular intervals within the 2 h following administration. The EEG signal was processed by power spe...

journal_title：Neuropsychobiology

authors： Sannita WG,Balbi A,Giacchino F,Rosadini G

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Psychosis spectrum disorders, especially schizophrenia, have been linked to disturbed dopaminergic activity in the brain. Plasma homovanillic acid (pHVA) levels partly represent dopaminergic metabolism in the central nervous system. In the present study associations between (changes in) pHVA levels, symptom ...

journal_title：Neuropsychobiology

authors： van de Kerkhof NW,Fekkes D,van der Heijden FM,Egger JI,Verhoeven WM

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Abnormalities in different parameters of the norepinephrine system have been widely described in major depression. The presence of alpha(2)-adrenoreceptors in blood platelets, similar to those in the brain, prompted us to evaluate them in depressed patients, as compared with healthy controls. METHODS:Fiftee...

journal_title：Neuropsychobiology

authors： Marazziti D,Baroni S,Masala I,Di Nasso E,Giannaccini G,Betti L,Lucacchini A,Cassano GB

更新日期：2001-01-01 00:00:00

abstract：:The cerebrospinal fluid (CSF) concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) as well as their ratios and correlations were analyzed in relation to the season of birth. The sample consisted of 241 drug-free patients par...

journal_title：Neuropsychobiology

authors： Chotai J,Asberg M

更新日期：1999-01-01 00:00:00

abstract：:The serotonergic system has been implicated in the production of the N1 and P2 components of auditory evoked potentials (AEPs). Moreover, studies have indicated the influence of heritability in the genesis of these AEP components. The serotonin transporter is the major site of serotonin reuptake into the presynaptic n...

journal_title：Neuropsychobiology

authors： Chen TJ,Yu YW,Chen MC,Tsai SJ,Hong CJ

更新日期：2002-01-01 00:00:00

abstract：:There is increasing evidence for an influence of directed attention on prepulse inhibition (PPI) of the acoustic startle reflex. However, the existing paradigms for the assessment of this effect have methodological problems and pitfalls. In particular, most previous studies used a paradigm which directed the attention...

journal_title：Neuropsychobiology

authors： Heekeren K,Meincke U,Geyer MA,Gouzoulis-Mayfrank E

更新日期：2004-01-01 00:00:00

abstract：:The aim of this paper was to determine whether the prolonged decrease in seizure threshold produced by chemical kindling was accompanied by behavioural changes in tests of anxiety and aggression. The responses of rats in five tests were examined after chronic treatment with the benzodiazepine inverse agonist FG7142. T...

journal_title：Neuropsychobiology

authors： Taylor SC,Johnston AL,Wilks LJ,Nicholass JM,File SE,Little HJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:The availability of tobacco products is associated with the likelihood that adolescents will begin using tobacco. Yet the relationship between nicotine availability and voluntary consumption has not been tested experimentally in developing rats. METHOD:The impact of environmental availability on adolescent ...

journal_title：Neuropsychobiology

authors： Biondolillo KD,Pearce AR

更新日期：2007-01-01 00:00:00

abstract：:Both thyrotropin-releasing hormone (TRH) and amphetamine antagonize pentobarbital. They are more effective in the day than at night. This is true for TRH even when the dose of pentobarbital is increased at night to prolong sedation. Under this condition the day-night difference is lost for amphetamine. Both substances...

journal_title：Neuropsychobiology

authors： Prange AJ Jr,Breese GR,Jahnke GD,Cooper BR,Cott JM,Wilson IC,Lipton MA,Plotnikoff NP

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND/AIMS:Recent findings suggest an involvement of insulin-like growth factor-1 (IGF-1) in the pathogenesis of many psychiatric disorders; however, there is a lack of data regarding IGF-1 in patients with obsessive-compulsive disorder (OCD). The aims of the present study were (1) to analyze putative alterations ...

journal_title：Neuropsychobiology

authors： Rosso G,Zanardini R,Chiodelli DF,Ferrari C,Gennarelli M,Bocchio-Chiavetto L

更新日期：2016-01-01 00:00:00

abstract：:The acute effects of alcohol (0.7 g/kg) on visual signal detection performance and critical flicker fusion frequency (CFF) of normal volunteers were investigated using a signal detection theory analysis. When signal probability was low, alcohol affected the stimulus sensitivity and the reaction times of hits. Under a ...

journal_title：Neuropsychobiology

authors： Jansen AA,de Gier JJ,Slangen JL

更新日期：1985-01-01 00:00:00

abstract：:We present a randomized double-blind study on the efficacy of caroverine in the treatment of alcohol withdrawal symptoms. The group B Ca2+ channel blocking agent caroverine was tested against meprobamate in inpatient treatment of alcohol withdrawal. Patients of both groups were similar in age, weight, duration of drin...

journal_title：Neuropsychobiology

authors： Koppi S,Eberhardt G,Haller R,König P

更新日期：1987-01-01 00:00:00

abstract：:The effects of the dopaminergic agonists (L-dopa, pergolide) and antagonists (haloperidol, clozapin) and a cholinergic agonist (tacrine) and antagonist (mecamylamine) on the voluntary intake of nicotine were investigated with the 2-bottle paradigm with the test drugs being dissolved directly in the drinking fluid of t...

journal_title：Neuropsychobiology

authors： Kameda G,Dadmarz M,Vogel WH

更新日期：2000-01-01 00:00:00

abstract：:In a double-blind, placebo-controlled, multiple-ascending-dose study, the encephalotropic and psychotropic properties of ABIO-08/01, a new potentially anxiolytic and nootropic isoxazoline, were studied in 16 young healthy males. In a randomized nonbalanced phase 1 study, they received 3 oral drug doses (10, 20, 40 mg)...

journal_title：Neuropsychobiology

authors： Saletu-Zyhlarz GM,Anderer P,Wolzt M,Semlitsch HV,Assandri A,Nessi P,Nannipieri F,Rosini S,Saletu B

更新日期：2009-01-01 00:00:00

abstract：:The effects of two benzodiazepines (alprazolam and bromazepam) on performance and event-related brain potentials (ERPs) in visual search and verbal recognition memory paradigms were tested in a placebo-controlled double-blind paradigm employing 12 young healthy subjects. Both drugs exerted similar effects on performan...

journal_title：Neuropsychobiology

authors： Münte TF,Gehde E,Johannes S,Seewald M,Heinze HJ

更新日期：1996-01-01 00:00:00

abstract：:The relationship between clinical effect of imipramine (IP) in 39 depressed patients and biochemical distinction, serum drug levels, and diagnostic classification was investigated retrospectively. Based on pretreatment plasma ratios of tryptophan and tyrosine to competing amino acids, which reflect the availability of...

journal_title：Neuropsychobiology

authors： Møller SE,Reisby N,Elley J,Krautwald O,Ortmann J,Larsen OB

更新日期：1985-01-01 00:00:00

abstract：:Recent findings indicate that the memory-impairing effects of benzodiazepines may preferentially involve the basolateral nucleus of the amygdala. To test this hypothesis we examined the effects on pretrial injection of diazepam into the central as compared to the lateral/basolateral amygdaloid nuclei on memory for a c...

journal_title：Neuropsychobiology

authors： Silva MA,Tomaz C

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:In depressed patients, overstimulation of the hypothalamo-pituitary-adrenocortical (HPA) system, probably caused by glucocorticoid receptor resistance, is the most consistent neurobiological finding. Glucocorticoids themselves are reported to increase leptin synthesis and secretion in humans. METHODS:We exa...

journal_title：Neuropsychobiology

authors： Himmerich H,Zimmermann P,Ising M,Kloiber S,Lucae S,Kunzel HE,Binder EB,Holsboer F,Uhr M

更新日期：2007-01-01 00:00:00

abstract：:28 cases of suicide committed in a Swedish population subjected to repeated psychiatric investigations are described. Two groups of controls were selected from the same population: sex- and age-matched living persons (normal group) and sex-matched persons who had died from organic disease at ages corresponding to thos...

journal_title：Neuropsychobiology

authors： Hagnell O,Rorsman B

更新日期：1979-01-01 00:00:00

abstract：:Regular repetition of one monitor of sensory perception and another of psychomotor perception revealed similar frequency and amplitude aspects of spontaneous endogenous free-running cycles of perception and others of vigilance. The ultradian periodicities of these cycles distinguish between persons with intact nervous...

journal_title：Neuropsychobiology

authors： Lovett Doust JW,Podnieks I

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND/AIMS:Valproic acid or valproate (VA) is an anticonvulsant and mood-stabilizing drug primarily used in the treatment of epilepsy and bipolar disorder. Ziprasidone (ZPN) is an atypical antipsychotic drug used mainly for the treatment of schizophrenia. METHODS:This study is a part of our investigation on the c...

journal_title：Neuropsychobiology

authors： Karapidaki I,Ekonomopoulou MT,Akritopoulou K,Anestakis D,Iakovidou-Kritsi Z

更新日期：2011-01-01 00:00:00

abstract：:Diabetes mellitus can induce impairment in learning and memory. Cognitive and memory deficits are common in older adults and especially in those with diabetes. This is mainly because of hyperglycemia, oxidative stress, and vascular abnormalities. Coenzyme Q10 (CoQ10) can decrease oxidative stress, hyperglycemia, and i...

journal_title：Neuropsychobiology

authors： Monsef A,Shahidi S,Komaki A

更新日期：2019-01-01 00:00:00

abstract：:The relationships between sensation seeking, curiosity about sex, and total and free testosterone in inmates were investigated. The role of other hormones such as luteinizing hormone (LH), follicle-stimulating hormone (FSH), and sex hormone-binding globulin (SHBG) in these relationships was also analyzed. Previous ana...

journal_title：Neuropsychobiology

authors： Aluja A,García LF

更新日期：2005-01-01 00:00:00

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for many neurotransmitter receptors. Among the adverse effects of clozapine, urinary incontinence is commonly found and is suggested to be caused by alpha-adrenergic blockade. We tested the hypothesis that clozapine-induced urinary incontinence is...

journal_title：Neuropsychobiology

authors： Hsu JW,Wang YC,Lin CC,Bai YM,Chen JY,Chiu HJ,Tsai SJ,Hong CJ

更新日期：2000-01-01 00:00:00

abstract：:Using event-related potentials (ERPs), a reduction in the auditory N100, N200 and P300 amplitude has been found in schizophrenic patients and may represent some pathophysiological deficit. Therefore, we investigated whether the genetic variant of the serotonin-2A receptor is associated with ERP change after clozapine ...

journal_title：Neuropsychobiology

authors： Yu YW,Tsai SJ,Yang KH,Lin CH,Chen MC,Hong CJ

更新日期：2001-01-01 00:00:00