Abstract:
:Abnormal anterior pituitary responsiveness to acute administration of thyrotropin-releasing hormone was investigated in 8 patients, 6 women and 2 men, with primary affective disorders in a depressive phase and in 2 women with schizoaffective disorders. Thyrotropin-releasing hormone, 500 micrograms i.v., induced a rise of plasma growth hormone levels in 1 patient suffering from primary affective disorders and in the 2 schizoaffective subjects, a rise of follicle-stimulating hormone in 1 schizoaffective patient, of luteinizing hormone in the 2 schizoaffective patients, an excessive prolactin rise in 5 patients with primary affective disorders and in 1 schizoaffective subject and a flat response of thyroid-stimulating hormone in 4 patients with primary affective disorders and in 2 schizoaffective patients. Desipramine was given at a dose of 50-100 mg/day for 3-5 weeks. The thyrotropin-releasing hormone stimulation test was repeated when the patients were improving or after 5 weeks of treatment without improvement. The hormonal impairments tended to disappear in those patients showing symptomatic improvement and were still present in those who did not improve.
journal_name
Neuropsychobiologyjournal_title
Neuropsychobiologyauthors
Brambilla F,Scarone S,Massironi R,Nobile P,Pugnetti Ldoi
10.1159/000117908subject
Has Abstractpub_date
1982-01-01 00:00:00pages
269-75issue
5eissn
0302-282Xissn
1423-0224journal_volume
8pub_type
杂志文章abstract::Clinical observations have suggested that lithium may exert adverse effects on memory. The difficulty in achieving empirical consensus regarding this issue has reflected several methodological problems: diversity of research designs, heterogeneous samples, lack of control groups and the possible confounding of memory ...
journal_title:Neuropsychobiology
pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章
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journal_title:Neuropsychobiology
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更新日期:2002-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000054930
更新日期:2001-01-01 00:00:00
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journal_title:Neuropsychobiology
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journal_title:Neuropsychobiology
pub_type: 杂志文章
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更新日期:1992-01-01 00:00:00
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更新日期:1999-01-01 00:00:00
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doi:10.1159/000054950
更新日期:2002-01-01 00:00:00
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journal_title:Neuropsychobiology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000503750
更新日期:2020-01-01 00:00:00
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journal_title:Neuropsychobiology
pub_type: 杂志文章
doi:10.1159/000501025
更新日期:2019-01-01 00:00:00
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journal_title:Neuropsychobiology
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更新日期:2004-01-01 00:00:00
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journal_title:Neuropsychobiology
pub_type: 临床试验,杂志文章
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更新日期:1990-01-01 00:00:00
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journal_title:Neuropsychobiology
pub_type: 杂志文章,评审
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更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2016-01-01 00:00:00
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journal_title:Neuropsychobiology
pub_type: 杂志文章
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更新日期:1975-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
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journal_title:Neuropsychobiology
pub_type: 杂志文章
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更新日期:1980-01-01 00:00:00