Lithium RBC/plasma ratio in subgroups of patients with affective disorders.

abstract：:77 primary depressive in-patients aged 18-70 years (mean = 46/47 years) were assigned randomly to experimental and control groups and treated in double-blind conditions in ten centers. Butriptyline and amitriptyline were both administered with an identical increasing schedule, up to 150 mg daily in the first week and ...

journal_title：Neuropsychobiology

authors： Guelfi JD,Dreyfus JF,Delcros M,Pichot P

更新日期：1983-01-01 00:00:00

abstract：:The prevalence of an abnormal response to the 1 mg dexamethasone suppression test (DST) was examined in 40 inpatients suffering from a major depressive disorder (MDD), 17 inpatients suffering from schizophrenia, and 30 normal controls. 23.5% of the schizophrenics were DST nonsuppressors compared to 52.5% of MDD patien...

journal_title：Neuropsychobiology

authors： Asnis GM,Eisenberg J,Lemus CZ,Halbreich U

更新日期：1986-01-01 00:00:00

abstract：:Previously, we performed an MRI study that revealed smaller volumes of the subregions of the cerebellar vermis in men and women with chronic schizophrenia. An issue that arose from that study was whether similar structural changes in the cerebellum are found in patients with first-episode schizophrenia. In the present...

journal_title：Neuropsychobiology

authors： Okugawa G,Nobuhara K,Takase K,Kinoshita T

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:Neurotrophins such as brain-derived neurotrophic factor (BDNF) are vital for neuronal survival and adaptive plasticity. With high BDNF gene expression in the prefrontal cortex, BDNF is a potential regulatory factor for building and maintaining cognitive reserves. Recent studies suggest that individual d...

journal_title：Neuropsychobiology

authors： Koven NS,Collins LR

更新日期：2014-01-01 00:00:00

abstract：:Both thyrotropin-releasing hormone (TRH) and amphetamine antagonize pentobarbital. They are more effective in the day than at night. This is true for TRH even when the dose of pentobarbital is increased at night to prolong sedation. Under this condition the day-night difference is lost for amphetamine. Both substances...

journal_title：Neuropsychobiology

authors： Prange AJ Jr,Breese GR,Jahnke GD,Cooper BR,Cott JM,Wilson IC,Lipton MA,Plotnikoff NP

更新日期：1975-01-01 00:00:00

abstract：:Recent findings indicate that the memory-impairing effects of benzodiazepines may preferentially involve the basolateral nucleus of the amygdala. To test this hypothesis we examined the effects on pretrial injection of diazepam into the central as compared to the lateral/basolateral amygdaloid nuclei on memory for a c...

journal_title：Neuropsychobiology

authors： Silva MA,Tomaz C

更新日期：1995-01-01 00:00:00

abstract：:Cephalosporins may induce nonconvulsive status epilepticus (NCSE), a potentially reversible condition. Despite the wide use of these antibiotics, there are only few reported cases, because this condition is probably underestimated. We report two new cases of NCSE occurring during treatment with cefepime and ceftazidim...

journal_title：Neuropsychobiology

authors： Primavera A,Cocito L,Audenino D

更新日期：2004-01-01 00:00:00

abstract：:Three anxiolytic drugs (bromazepam 3 mg, buspirone 10 mg, and clobazam 10 mg p.o.) were evaluated for their effects on memory, psychomotor performance and subjective response in a double-blind, placebo-controlled, crossover study in 20 healthy volunteers. At each session, measurements were made before and 2 and 6 h af...

journal_title：Neuropsychobiology

authors： Bourin M,Auget JL,Colombel MC,Larousse C

更新日期：1989-01-01 00:00:00

abstract：:Single, 50- and 100-mg oral doses of phenobarbital and a matching placebo were administered double-blind to 8 young, healthy male subjects. Multilead electroencephalographic (EEG) samples were recorded prior to, and at regular intervals within the 2 h following administration. The EEG signal was processed by power spe...

journal_title：Neuropsychobiology

authors： Sannita WG,Balbi A,Giacchino F,Rosadini G

更新日期：1990-01-01 00:00:00

abstract：:The relation between EEG spectral power and alterations of the visual evoked potential (VEP) during different behavioral states and after intraperitoneal application of neuroactive drugs have been investigated in Long-Evans rats. FFT power and field potential maps were made in five behavioral states of the unrestraine...

journal_title：Neuropsychobiology

authors： Bringmann A,Klingberg F

更新日期：1995-01-01 00:00:00

abstract：:Dopamine depletion induced by administration of Ro4-1284 produces a condition of rapid and repeated eye blinking in rats. This condition mimics the human disorder, blepharospasm, which often accompanies parkinsonism and other dopamine deficiency disorders. When given a 3-week course of a compound (SR-3) developed from...

journal_title：Neuropsychobiology

authors： Mostofsky DI,Yehuda S,Rabinovitz S,Carasso R

更新日期：2000-01-01 00:00:00

abstract：:This study was aimed to test the association between schizophrenia and a functional serotonin polymorphism (5-HTTLPR) in the upstream regulatory region. Genomic DNA analysis with polymerase chain reaction was used for 5-HTTLPR genotyping. One hundred and eleven patients with schizophrenia and 208 healthy individuals p...

journal_title：Neuropsychobiology

authors： Pae CU,Kim JJ,Lee SJ,Lee CU,Lee C,Paik IH,Park HR,Yang S,Serretti A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Structural brain changes and cognitive impairments have been identified as indicators of genetic risk for schizophrenia. However, the pattern of associations between such structural and functional liability markers has been less well investigated. METHODS:Magnetic resonance imaging data and cognitive assess...

journal_title：Neuropsychobiology

authors： Habets P,Krabbendam L,Hofman P,Suckling J,Oderwald F,Bullmore E,Woodruff P,Van Os J,Marcelis M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:So-called Porteus mazes are used to investigate prefrontal cortex (PFC) functioning in normal subjects and patients with different neuropsychiatric disorders. Here we present data confirming the involvement of the PFC for the first time by means of functional magnetic resonance imaging (fMRI). To minimize mo...

journal_title：Neuropsychobiology

authors： Kirsch P,Lis S,Esslinger C,Gruppe H,Danos P,Broll J,Wiltink J,Gallhofer B

更新日期：2006-01-01 00:00:00

abstract：:Quantitative assessment of regional cerebral blood flow (rCBF) was performed in a 22-year-old man with intractable temporal lobe epilepsy on long-term high-dose phenytoin (PHT) therapy, using single photon emission computed tomography (SPECT) with N-isopropyl-(iodine-123)-p-iodoamphetamine. In all the SPECT scans repe...

journal_title：Neuropsychobiology

authors： Jibiki I,Kido H,Yamaguchi N,Matsuda H,Hisada K

更新日期：1993-01-01 00:00:00

abstract：:The acute effects of alcohol (0.7 g/kg) on visual signal detection performance and critical flicker fusion frequency (CFF) of normal volunteers were investigated using a signal detection theory analysis. When signal probability was low, alcohol affected the stimulus sensitivity and the reaction times of hits. Under a ...

journal_title：Neuropsychobiology

authors： Jansen AA,de Gier JJ,Slangen JL

更新日期：1985-01-01 00:00:00

abstract：:The performance on spatial and nonspatial associative learning tasks was tested in a sample of male drug-free DSM III-diagnosed schizophrenic patients and in a closely matched normal control group. Schizophrenics showed a worse performance on both versions of the task, but especially on the nonspatial one. A significa...

journal_title：Neuropsychobiology

authors： Kemali D,Maj M,Galderisi S,Monteleone P,Mucci A

更新日期：1987-01-01 00:00:00

abstract：:This study aimed to investigate the binding affinity of [3H]GABA and [3H]beta-alanine to GABA transporters GAT-1 and GAT-3 in the human dorsolateral prefrontal cortex (Brodmanns' area 9) in schizophrenia. Using post mortem tissue from individuals diagnosed with schizophrenia (n=6) and control subjects (n=6), the densi...

journal_title：Neuropsychobiology

authors： Schleimer SB,Hinton T,Dixon G,Johnston GA

更新日期：2004-01-01 00:00:00

abstract：:Two preliminary studies have indicated a variation in season of birth in severely language-disordered children. In the current study, the season of birth in 472 Danish children with language disorder born between 1958 and 1976 was compared with the season of birth of all Danish live-born children in the same period. F...

journal_title：Neuropsychobiology

authors： Hauschild KM,Mouridsen SE,Nielsen S

更新日期：2005-01-01 00:00:00

abstract：:Nitric oxide (NO) has been implicated to play a role in the pathogenesis of depressive disorders. Adrenomedullin (AM) induces vasorelaxation by activating adenylate cyclase and also by stimulating the release of NO. AM immune reactivity is present in the brain, consistent with a role as neurotransmitter. Therefore, it...

journal_title：Neuropsychobiology

authors： Savaş HA,Herken H,Yürekli M,Uz E,Tutkun H,Zoroğlu SS,Ozen ME,Cengiz B,Akyol O

更新日期：2002-01-01 00:00:00

abstract：:Hallucinogenic drug-induced states are considered as models for acute schizophrenic disorders (experimental psychoses). In a double-blind study with healthy volunteers we investigated the influence of the serotonergic hallucinogen psilocybin, the ecstasy-like drug 3,4-methylenedioxyethylamphetamine (MDE), the stimulan...

journal_title：Neuropsychobiology

authors： Gouzoulis-Mayfrank E,Thelen B,Maier S,Heekeren K,Kovar KA,Sass H,Spitzer M

更新日期：2002-01-01 00:00:00

abstract：:The brain activity of 13 right-handed students (6 men and 7 women) was determined using high resolution (99m)Tc-HMPAO brain SPECT images during visuospatial tasks. The results showed that there was no significant gender-specific difference in solving the visuospatial tasks and that no meaningful statistical difference...

journal_title：Neuropsychobiology

authors： Unterrainer J,Wranek U,Staffen W,Gruber T,Ladurner G

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Schizophrenia is a genetically complex disorder with an unknown pathophysiology. Several genes implicated in glutamate metabolism have been associated with the disorder. Recent studies of polymorphisms in the dystrobrevin-binding protein 1 gene (DTNBP1; dysbindin) and D-amino-acid-oxidase (DAO) gene, both in...

journal_title：Neuropsychobiology

authors： Wirgenes KV,Djurovic S,Agartz I,Jonsson EG,Werge T,Melle I,Andreassen OA

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Butyrate is a short-chain fatty acid metabolite produced by microbiota in the colon. With its antioxidant properties, butyrate has also been shown to alter the neurological functions in affective disorder models, suggesting it as a key mediator in gut-brain interactions. OBJECTIVE:Here, we evaluated the n...

journal_title：Neuropsychobiology

authors： Rode J,Yang L,König J,Hutchinson AN,Wall R,Venizelos N,Brummer RJ,Rangel I,Vumma R

更新日期：2020-10-19 00:00:00

abstract：BACKGROUND:Reaction time variability (RTV) is considered a valid endophenotype of attention deficit/hyperactivity disorder (ADHD). It is also often used to examine the efficacy of drug treatment or individual patients' treatment responses and has been furthermore suggested to significantly reduce the potential number o...

journal_title：Neuropsychobiology

authors： Grant P,Kuepper Y,Wielpuetz C,Hennig J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Eugen Bleuler, in his book Dementia praecox oder Gruppe der Schizophrenien, discussed issues of social psychiatry, and he considered complex interventions pivotal in the care for people with schizophrenia. Bleuler emphasised the potential of therapeutic communities in providing care, the drawbacks of extende...

journal_title：Neuropsychobiology

authors： Becker T,Kösters M

更新日期：2012-01-01 00:00:00

abstract：:28 cases of suicide committed in a Swedish population subjected to repeated psychiatric investigations are described. Two groups of controls were selected from the same population: sex- and age-matched living persons (normal group) and sex-matched persons who had died from organic disease at ages corresponding to thos...

journal_title：Neuropsychobiology

authors： Hagnell O,Rorsman B

更新日期：1979-01-01 00:00:00

abstract：:The effects of febarbamat and pipamperon on agitational and aggressive states of patients with diffuse psycho-organic syndrome were compared in a double-blind study on patients over 60 years of age requiring nursing care. Such disorders, particularly in the field of psychiatric gerontology, represent an increasing pro...

journal_title：Neuropsychobiology

authors： Brenner HD,Alberti L,Keller F,Schaffner L

更新日期：1984-01-01 00:00:00

abstract：:Schizophrenia is a heterogeneous and multidimensional disorder. The different syndromes or dimensions of this disorder represent distinct pathophysiological processes. Evidence is growing that each of the composite syndromes or dimensions of this disorder is associated with specific validators. This article reviewed n...

journal_title：Neuropsychobiology

authors： Aderibigbe YA,Gureje O

更新日期：1996-01-01 00:00:00

abstract：:Fengabine is a new GABAmimetic compound active in animal models predictive of antidepressant activity. The present overview reports the results of 6 double-blind trials versus tricyclics (TCAs) (3 in outpatients and 3 in inpatients). Overall, 398 adult patients (149 males and 249 females) were treated; 194 with fengab...

journal_title：Neuropsychobiology

authors： Magni G,Garreau M,Orofiamma B,Palminteri R

更新日期：1989-01-01 00:00:00