Abstract:
:The behavioural effects of increasing doses of apomorphine and haloperidol were observed in a group of six marmosets. Behaviour was classified quantitatively into categories: Locomotion, inactivity, checking (small head movements), social interaction and purposeful activities. Statistical analysis revealed that apomorphine had a stimulant effect on checking and locomotion which could be antagonized by haloperidol. Activities and social contact were severly reduced by both apomorphine and haloperidol. Inactivity was increased by the lowest dose of apomorphine in otherwise untreated animals. It is suggested that haloperidol antagonizes the stimulant effects of apomorphine but is synergistic to its suppressant effects, and that the low dose effect of apomorphine on inactivity is mediated by a mechanism which may be different from that acted upon by haloperidol.
journal_name
Psychopharmacology (Berl)journal_title
Psychopharmacologyauthors
Scraggs PR,Baker HF,Ridley RMdoi
10.1007/BF00431987subject
Has Abstractpub_date
1979-01-01 00:00:00pages
41-3issue
1eissn
0033-3158issn
1432-2072journal_volume
66pub_type
杂志文章abstract::The effects of benzodiazepine (triazolam 0.25 and 0.50 mg) on different aspects of cognitive function were assessed. Triazolam impaired free recall and recognition of information presented after drug administration. In contrast to these impairments in explicit memory, a memory function that did not require conscious a...
journal_title:Psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::The urinary excretion of 4-hydroxy-3-methoxyphenylglycol was compared in a group of 23 depressive patients and 27 control subjects of similar age. There was no difference between patients and controls although female controls excreted less than males. After 6 weeks' treatment with 150 mg daily of amitriptyline there w...
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pub_type: 杂志文章,评审
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journal_title:Psychopharmacology
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00432506
更新日期:1985-01-01 00:00:00
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doi:10.1007/s00213-018-4979-4
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journal_title:Psychopharmacology
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doi:10.1007/BF02245214
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journal_title:Psychopharmacology
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journal_title:Psychopharmacology
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00174512
更新日期:1988-01-01 00:00:00
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journal_title:Psychopharmacology
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journal_title:Psychopharmacology
pub_type: 杂志文章,随机对照试验
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journal_title:Psychopharmacology
pub_type: 临床试验,杂志文章
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journal_title:Psychopharmacology
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doi:10.1007/BF00212779
更新日期:1988-01-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00213-007-0963-0
更新日期:2008-02-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/s002130000531
更新日期:2000-10-01 00:00:00
abstract::In the studies reported here, we investigated the effects of nicotine on memory for unrelated word lists. Nicotine was delivered through cigarette smoking, and memory performance was assessed using both intentional and incidental recall tasks, and employing an additional, indirect measure of memory. We report the resu...
journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF02245856
更新日期:1995-06-01 00:00:00
abstract::The place-preference paradigm was evaluated as a measure of morphine's positive reinforcing properties. Previous place-preference studies obtained a morphine place preference of 26%-63%. In order to examine whether differences in procedure may account for this scatter, the present experiment investigated whether there...
journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00432040
更新日期:1984-01-01 00:00:00
abstract::Carbachol, muscarine, eserine and neostigmine injected into the cerebral ventricles of conscious cats evoked emotional behaviour with aggression, autonomic and motor phenomena as well as clonic-tonic convulsions. The main and the most impressive feature of the gross behavioural effects of intraventricular carbachol, m...
journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00427131
更新日期:1979-04-11 00:00:00
abstract:RATIONALE:The ultra-short-acting mu opioid agonist analgesic/anesthetic remifentanil (RMF) is extremely rapidly eliminated from blood (half-life in rats, 0.3-0.7 min). This extremely fast elimination is thought to be the main reason why RMF maintains such high rates of responding in animal operant-conditioning models o...
journal_title:Psychopharmacology
pub_type: 杂志文章
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更新日期:2005-12-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/s00213-004-1914-7
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:In recent years, there has been growing research interest in using nicotine replacement medications to aid smoking reduction prior to a quit attempt. Gaining a better understanding of how treatments influence smoking reduction may allow for better tailoring of treatments and, ultimately, better cessation out...
journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/s00213-017-4604-y
更新日期:2017-07-01 00:00:00