Effects of pharmacological doses of 2-deoxyglucose on plasma catecholamines and glucose levels in patients with schizophrenia.

abstract：:Effects of chlordiazepoxide (CDP) and ethanolamine-O-sulphate (EOS) alone and in combination were tested on the acquisition and performance of continuous reinforcement - time out (CR-TO) and variable interval reinforcement - time out (VI-TO) operant discriminations in rats. CDP disrupted acquisition of CR-TO discrimin...

journal_title：Psychopharmacology

authors： Hodges H,Baum S,Taylor P,Green S

更新日期：1986-01-01 00:00:00

abstract：RATIONALE:The positive modulation of gamma-aminobutyric acid type-A (GABAA) receptors is a putative mechanism via which alcohol escalates aggressive behavior. Broad-spectrum benzodiazepine antagonists block alcohol-heightened aggression in rats and monkeys. However, the degree to which GABAA subunit composition plays a...

journal_title：Psychopharmacology

authors： de Almeida RM,Rowlett JK,Cook JM,Yin W,Miczek KA

更新日期：2004-03-01 00:00:00

abstract：RATIONALE:Longitudinal, population-based studies can better assess the relationship of ecstasy use with depression. OBJECTIVES:We examined whether change in ecstasy use was associated with change in depressive symptoms/probable depression over a 4-year period, among a large Australian sample. METHODS:The Personality ...

journal_title：Psychopharmacology

authors： George AM,Olesen S,Tait RJ

更新日期：2013-10-01 00:00:00

abstract：RATIONALE:The metabotropic glutamate (mGlu5) receptor subtype 5 antagonist MPEP attenuates self-administration of numerous drugs of abuse. OBJECTIVES:The purpose of the present study was to explore whether MPEP-induced decreases in nicotine and cocaine self-administration reflect attenuation of the reinforcing and inc...

journal_title：Psychopharmacology

authors： Paterson NE,Markou A

更新日期：2005-04-01 00:00:00

abstract：:Rats were chronically administered either haloperidol (HAL) or fluphenazine (FLU) via depot injections for 8 months, given these same drugs in their drinking water for the next 2 months, and then withdrawn from the drugs. Throughout the experiment the animals were tested repeatedly in an enclosed tube using a computer...

journal_title：Psychopharmacology

authors： See RE,Levin ED,Ellison GD

更新日期：1988-01-01 00:00:00

abstract：RATIONALE:Previous observations revealed that defeated and subsequently individually housed rats do not display behavioral anticipatory responses to the conditioned presentation of a bell/light stimulus associated with free access to a 5% sucrose solution reward. The absence of the appetitive responses suggests a decre...

journal_title：Psychopharmacology

authors： Von Frijtag JC,Van den Bos R,Spruijt BM

更新日期：2002-07-01 00:00:00

abstract：:Progabide inhibited male rat sexual behavior at a dose of 200 mg/kg. This dose had only modest effects on ambulatory activity and no effect at all on motor coordination as evaluated by a rotarod test. The GABAA antagonist bicuculline, at a dose of 1 mg/kg, blocked the effects of progabide on sex behavior. In contrast,...

journal_title：Psychopharmacology

authors： Agmo A,Paredes RG,Sierra L,Garcés I

更新日期：1997-01-01 00:00:00

abstract：RATIONALE:A variety of behavioral procedures have been developed to assess cannabinoid activity in mice; however, the feasibility of establishing Delta(9)-THC as a discriminative stimulus in mice has not been documented. OBJECTIVE:One goal was to establish Delta(9)-THC as a discriminative stimulus in mice; after havin...

journal_title：Psychopharmacology

authors： McMahon LR,Ginsburg BC,Lamb RJ

更新日期：2008-07-01 00:00:00

abstract：RATIONALE:Opioid use disorder (OUD) is a major epidemic in the USA. Despite evidence indicating that OUD may be particularly severe for women, preclinical models have yet to establish sex as a major factor in OUD. OBJECTIVES:Here, we examined sex differences in vulnerability to relapse following intermittent access fe...

journal_title：Psychopharmacology

authors： Bakhti-Suroosh A,Towers EB,Lynch WJ

更新日期：2021-01-06 00:00:00

abstract：RATIONALE:Virtually all cocaine self-administration studies have used a "unit dose" as a reinforcing stimulus; the subject is a passive recipient of an experimenter-selected dose. OBJECTIVES:The present experiments examined the consequence of requiring the subject to actively determine the dose and speed of each injec...

journal_title：Psychopharmacology

authors： Roberts DCS,Zimmer BA

更新日期：2020-09-01 00:00:00

abstract：:The effects of benzodiazepine (triazolam 0.25 and 0.50 mg) on different aspects of cognitive function were assessed. Triazolam impaired free recall and recognition of information presented after drug administration. In contrast to these impairments in explicit memory, a memory function that did not require conscious a...

journal_title：Psychopharmacology

authors： Weingartner HJ,Hommer D,Lister RG,Thompson K,Wolkowitz O

更新日期：1992-01-01 00:00:00

abstract：:The conditioned place preference technique was used to assess the affective properties of the direct dopamine D1 agonist, SKF38393, and the direct D2 agonist, LY171555 (quinpirole). A three compartment apparatus was used: the animals' pre-experimental preference for the two choice compartments was equal and, within ea...

journal_title：Psychopharmacology

authors： White NM,Packard MG,Hiroi N

更新日期：1991-01-01 00:00:00

abstract：:Effects of the dopamine D2 receptor antagonist sulpiride and the D1 antagonist SCH-23390 were examined, in rats, in two-bottle preference tests (sucrose versus water) and in single-bottle tests, at different sucrose concentrations. Both drugs decreased sucrose intake in single bottle tests, at low sucrose concentratio...

journal_title：Psychopharmacology

authors： Muscat R,Willner P

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Traumatic events are associated with alcohol use problems with increased alcohol craving as a potential mediator. There is still a lack of knowledge regarding the causal nature of this association and its underlying mechanisms. This study investigated the effects of acute trauma exposure on alcohol craving i...

journal_title：Psychopharmacology

authors： Trautmann S,Kräplin A,Dieterich R,Richter J,Muehlhan M

更新日期：2018-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVE:Schizophrenia displays sex differences in many aspects. Decreased brain-derived neurotrophic factor (BDNF) levels have been reported to be associated with high body weight or obesity as well as other psychopathological aspects in schizophrenia patients. This study aimed to explore sex difference...

journal_title：Psychopharmacology

authors： Yang F,Wang K,Du X,Deng H,Wu HE,Yin G,Ning Y,Huang X,Teixeira AL,de Quevedo J,Soares JC,Li X,Lang X,Zhang XY

更新日期：2019-02-01 00:00:00

abstract：RATIONALE:Prior research suggests that high levels of acetylcholine (ACh) in the nucleus accumbens (NAc) are associated with aversive states such as morphine withdrawal, but this has not been tested for nicotine withdrawal. OBJECTIVES:The goal was to test the hypothesis that acute nicotine decreases extracellular ACh ...

journal_title：Psychopharmacology

authors： Rada P,Jensen K,Hoebel BG

更新日期：2001-08-01 00:00:00

abstract：:The relationship between premenstrual dysphoria and alcohol acquistion and use patterns was studied in 14 women over 35 days on a clinical research ward. A 7-day drug-free baseline was followed by 21 days of alcohol availability and a post-alcohol drug-free period of 7 days. Women could earn alcohol or 50 cents for 30...

journal_title：Psychopharmacology

authors： Mello NK,Mendelson JH,Lex BW

更新日期：1990-01-01 00:00:00

abstract：RATIONALE:A positive relationship exists between chronic ethanol intoxication experiences and the severity of neural hyperactivity and withdrawal seizures. An important possibility is that withdrawal reactions also influence the motivation to obtain and consume ethanol. OBJECTIVES:To test this hypothesis, the effects ...

journal_title：Psychopharmacology

authors： Ciccocioppo R,Lin D,Martin-Fardon R,Weiss F

更新日期：2003-07-01 00:00:00

abstract：RATIONALE:Available neurochemical probes that lower brain dopamine (DA) levels in man are limited by their tolerability and efficacy. For instance, the acute lowering of brain tyrosine is well tolerated, but only modestly lowers brain DA levels. Modification of tyrosine depletion to robustly lower DA levels would provi...

journal_title：Psychopharmacology

authors： Brodnik Z,Double M,Jaskiw GE

更新日期：2013-05-01 00:00:00

abstract：:Mice were trained on a one-trial inhibitory avoidance task and given immediate post-training intraperitoneal injections of cocaine (0.03-1.00 mg/kg). On a retention test 24 h later, the retention latencies of mice given the 0.10 mg/kg dose were significantly higher than those of the controls. The effect of cocaine on ...

journal_title：Psychopharmacology

authors： Introini-Collison IB,McGaugh JL

更新日期：1989-01-01 00:00:00

abstract：AIM:Excess consumption of alcohol leads to impaired cognition and decision making; hence, alcohol-containing products and advertising contain warning messages about the adverse effects of excess drinking. However, there is a need to understand how alcohol influences the processing of advisory messages. METHOD:The curr...

journal_title：Psychopharmacology

authors： Phillips JG,Ogeil RP

更新日期：2010-03-01 00:00:00

abstract：:Preclinical studies suggest that acoustic startle amplitude is increased during ethanol withdrawal. The current study evaluated the effects of intravenous infusion of the alpha 2-adrenergic antagonist, yohimbine (0.4 mg/kg), the serotonin partial agonist m-chlorophenylpiperazine (mCPP, 0.1 mg/kg), and placebo administ...

journal_title：Psychopharmacology

authors： Krystal JH,Webb E,Grillon C,Cooney N,Casal L,Morgan CA 3rd,Southwick SM,Davis M,Charney DS

更新日期：1997-06-01 00:00:00

abstract：:Pigeons were trained to peck each of two response keys. Periods during which pecks on one key (the food key) produced access to grain according to a random-ratio 80 schedule alternated irregularly with periods during which food-key responses had no scheduled consequences (extinction). Both keys remained amber unless a...

journal_title：Psychopharmacology

authors： Dearing ME,Branch MN

更新日期：1981-01-01 00:00:00

abstract：RATIONALE:Caffeine is commonly believed to offset the acute effects of alcohol, but some evidence suggests that cognitive processes remain impaired when caffeine and alcohol are coadministered. OBJECTIVES:No previous study has investigated the separate and joint effects of alcohol and caffeine on conflict monitoring a...

journal_title：Psychopharmacology

authors： Bailey K,Amlung MT,Morris DH,Price MH,Von Gunten C,McCarthy DM,Bartholow BD

更新日期：2016-04-01 00:00:00

abstract：:In order to study the role of dopamine (DA) in the regulation of seizure mechanisms in man, a non-emetic dose of apomorphine, a direct stimulant of DA receptors, was administered to eight patients effected by different types of epilepsy. The EEG changes induced by apomorphine administration in comparison to those elic...

journal_title：Psychopharmacology

authors： Del Zompo M,Tocco F,Marrosu F,Passino N,Corsini GU

更新日期：1983-01-01 00:00:00

abstract：:Many behavioral effects of cocaine are attenuated by dopamine (DA) receptor antagonists. Yet, long-term DA antagonist administration enhances neuronal responsiveness to DA in several pathways, including the mesolimbic system. This study compared the effects of short-term versus long-term administration of the DA antag...

journal_title：Psychopharmacology

authors： Kosten TA,DeCaprio JL,Nestler EJ

更新日期：1996-12-01 00:00:00

abstract：RATIONALE:The zebrafish dopaminergic system is thought to be evolutionarily conserved and may be amenable to pharmacological manipulation using drugs developed for mammalian receptors. However, only few studies have examined the role of specific receptor subtypes in behaviour of adult zebrafish. OBJECTIVES:The objecti...

journal_title：Psychopharmacology

authors： Tran S,Nowicki M,Muraleetharan A,Gerlai R

更新日期：2015-02-01 00:00:00

abstract：RATIONALE:Like other monoamine releasers such as D-amphetamine, chronic treatment with phenmetrazine can attenuate cocaine self-administration in monkeys. OBJECTIVES:The present studies extended this finding to rodents and to cocaine-primed reinstatement, a putative laboratory animal model of relapse. METHODS:In expe...

journal_title：Psychopharmacology

authors： Czoty PW,Tran P,Thomas LN,Martin TJ,Grigg A,Blough BE,Beveridge TJ

更新日期：2015-07-01 00:00:00

abstract：RATIONALE:Indirect-acting serotonin (5-HT) receptor agonists can enhance the antinociceptive effects of morphine; however, the specific 5-HT receptor subtype(s) mediating this enhancement is not established. OBJECTIVE:This study examined interactions between morphine and both 5-HT(1A) and 5-HT(2A) receptor agonists in...

journal_title：Psychopharmacology

authors： Li JX,Shah AP,Patel SK,Rice KC,France CP

更新日期：2013-02-01 00:00:00

abstract：:Three sets of experiments were carried out in a Y water maze in which mice had to swim toward the light or the dark, in two different procedures. The first procedure involved, orientation toward a light source (L procedure), corresponding to natural preference, the latter involved orientation toward the dark (D proced...

journal_title：Psychopharmacology

authors： Castellano C

更新日期：1976-08-17 00:00:00