Abstract：
:The relationship between premenstrual dysphoria and alcohol acquistion and use patterns was studied in 14 women over 35 days on a clinical research ward. A 7-day drug-free baseline was followed by 21 days of alcohol availability and a post-alcohol drug-free period of 7 days. Women could earn alcohol or 50 cents for 30 min of performance on a simple operant task. The Premenstrual Assessment Form (PAF) was administered during baseline and at the premenstruum. Menstrual cycle phase was associated with changes in alcohol use by 8 of the 14 women. Five women drank more during the premenstruum and scored higher on 12 of 18 PAF factors than women whose drinking remained the same (N = 6) or decreased (N = 3). Women who increased drinking had significantly higher PAF scores on impaired social functioning, hostility/anger and hysteroid features (P less than 0.05, 0.01). Women who drank less during the premenstruum reported more pain and physical discomfort, whereas women who drank about the same amount were relatively asymptomatic. PAF profiles reported at the premenstruum and baseline PAF profiles based on recall of the preceding three menstrual cycles were concordant in 13 of the 14 women (P less than 0.001-0.0001). These data suggest that women's perceptions of premenstrual symptomatology are stable through time.
journal_name
Psychopharmacology (Berl)journal_title
Psychopharmacologyauthors
Mello NK,Mendelson JH,Lex BWdoi
10.1007/BF02244221subject
Has Abstractpub_date
1990-01-01 00:00:00pages
448-55issue
4eissn
0033-3158issn
1432-2072journal_volume
101pub_type
杂志文章abstract：:In a phase II study the antidepressive effect of citalopram, a selective and potent serotonin reuptake inhibitor, was examined in 20 endogenously and three non-endogenously depressed hospitalized patients. Four endogenously depressed patients dropped out due to deterioration early in the treatment period. The remainin...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00464566
更新日期：1982-01-01 00:00:00
abstract：RATIONALE:Lithium is the most widely prescribed mood stabilizer, but the precise mechanism of lithium is unresolved. OBJECTIVE:We examine the effects of the administration of therapeutically relevant concentrations of lithium on the expression of brain-derived neurotrophic factor (BDNF) and its receptor, Trk B, as wel...
journal_title：Psychopharmacology
pub_type： 杂志文章
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更新日期：2001-10-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02244335
更新日期：1993-01-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-019-05308-x
更新日期：2019-08-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-013-2977-0
更新日期：2013-05-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-020-05524-w
更新日期：2020-08-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
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更新日期：2014-03-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00432251
更新日期：1982-01-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02244749
更新日期：1994-06-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00439545
更新日期：1989-01-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00427793
更新日期：1983-01-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-010-1777-z
更新日期：2010-03-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-004-1777-y
更新日期：2004-08-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-011-2501-3
更新日期：2012-04-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02245605
更新日期：1996-03-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-006-0625-7
更新日期：2007-02-01 00:00:00
abstract：RATIONALE:The gut microbiota is increasingly recognized as a potential mediator of psychiatric diseases. Depressed patients have been shown to have a different microbiota composition compared with healthy controls, and several lines of research now aim to restore this dysbiosis. To develop novel treatments, preclinical...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-018-5094-2
更新日期：2019-05-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-004-2060-y
更新日期：2005-05-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-017-4619-4
更新日期：2017-07-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章,评审
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更新日期：2011-11-01 00:00:00
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更新日期：2018-10-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00427828
更新日期：1983-01-01 00:00:00
abstract：RATIONALE AND OBJECTIVES:Functional (pharmacodynamic) ethanol tolerance can be evidenced within a single session of exposure to ethanol (acute or within-session tolerance), or after repeated ethanol exposures (chronic or between-session tolerance). To investigate whether acute and chronic tolerance to ethanol are inter...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s002130100722
更新日期：2001-06-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-009-1499-2
更新日期：2009-07-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00213-014-3453-1
更新日期：2014-07-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s002130050329
更新日期：1997-07-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00213-018-4996-3
更新日期：2018-09-01 00:00:00
abstract：RATIONALE:Although psilocybin has been used for centuries for religious purposes, little is known scientifically about its acute and persisting effects. OBJECTIVES:This double-blind study evaluated the acute and longer-term psychological effects of a high dose of psilocybin relative to a comparison compound administer...
journal_title：Psychopharmacology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00213-006-0457-5
更新日期：2006-08-01 00:00:00
abstract：RATIONALE:In an animal model for vulnerability to drug abuse, rats that are more reactive to a novel environment (high responders, HRs) are more sensitive to behavioral effects of psychostimulants than are less reactive rats (low responders, LRs). In a companion article, we reported that HRs and LRs differ in sensitivi...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-004-1921-8
更新日期：2004-12-01 00:00:00
abstract：:We have previously demonstrated that depletion of forebrain norepinephrine (NE) led to an attenuation of neophobia in a novel environment, as defined by a greater preference for novel food over familiar food. To study further the role of forebrain NE in neophobia we chronically infused noradrenergic receptor ligands o...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02253601
更新日期：1992-01-01 00:00:00
