Abstract：
:Suppressor of Hairless (Su(H)) is required at two stages of adult sensory organ development in Drosophila. Complete loss of Su(H) function results in a "neurogenic" phenotype in imaginal discs, in which too many cells adopt the sensory organ precursor cell fate. Su(H) is also involved in controlling the fates of sensillum accessory cells and is specifically expressed in two of these cells. Su(H) is the Drosophila homolog of the mouse J kappa RBP gene, whose product binds specifically to the recombination signal sequence of immunoglobulin J kappa segments. The Su(H) and J kappa RBP proteins are 82% identical over most of their length, and share with bacteriophage integrates and yeast recombinases a motif that includes residues directly involved in catalyzing recombination.
journal_name
Celljournal_title
Cellauthors
Schweisguth F,Posakony JWdoi
10.1016/0092-8674(92)90641-osubject
Has Abstractpub_date
1992-06-26 00:00:00pages
1199-212issue
7eissn
0092-8674issn
1097-4172pii
0092-8674(92)90641-Ojournal_volume
69pub_type
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