Abstract:
:Exposure to an acute stressful event enhances trace eyeblink conditioning in male rats, even when rats begin training days after the stressor (Shors, 2001). The authors examined whether the bed nucleus of the stria terminalis (BNST), an area involved in stress and anxiety, is critically involved in this effect and, if so, when. The authors found that excitotoxic lesions to the BNST prevented the enhanced conditioning after stressor exposure. In addition, temporary inactivation of the BNST during the stressor did not alter enhanced responding, whereas inactivation during training prevented the enhancement. These data indicate that stressful experience induces persistent changes in the BNST that are necessary for enhancing learning well after the stressful event has ceased.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Bangasser DA,Santollo J,Shors TJdoi
10.1037/0735-7044.119.6.1459subject
Has Abstractpub_date
2005-12-01 00:00:00pages
1459-66issue
6eissn
0735-7044issn
1939-0084pii
2006-00645-004journal_volume
119pub_type
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