A small amount of wheel running facilitates eating in nondeprived rats.

Abstract:

:A high level of dopaminergic activation such as that produced by a high dose of amphetamine suppresses eating, whereas a low level such as that produced by a low dose can have the opposite effect. Like a high dose of amphetamine, a high level of wheel running also suppresses eating. It was hypothesized that this suppression is due to dopaminergic activation produced by wheel running. If so, a relatively small amount of wheel running should produce a low level of dopaminergic activation and thus have the same effect as a low dose of amphetamine: facilitation of eating. In the present experiment, nondeprived rats were allowed to run in a wheel for 30 min before a feeding test. As predicted, a little wheel running facilitated eating in these rats relative to appropriate controls. The present results may be relevant to an understanding of eating disorders in humans.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Lett BT,Grant VL,Gaborko LL

doi

10.1037//0735-7044.110.6.1492

subject

Has Abstract

pub_date

1996-12-01 00:00:00

pages

1492-5

issue

6

eissn

0735-7044

issn

1939-0084

journal_volume

110

pub_type

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