Changes in late auditory evoked potentials induced by growth hormone-releasing hormone (GHRH) but not somatostatin (SRIF) after peripheral administration in male controls.

abstract：:Diapause pupae of the swallowtail butterfly Papilio xuthus L. exhibit diapause-green, orange and brownish-orange color polymorphism. Development of orange pupae involves a neuroendocrine factor inducing orange pupa (Orange-Pupa-Inducing Factor, OPIF), which is secreted from the head-thoracic region during late pharate...

journal_title：Peptides

authors： Yamanaka A,Adachi M,Imai H,Uchiyama T,Inoue M,Islam AT,Kitazawa C,Endo K

更新日期：2006-03-01 00:00:00

abstract：:CR 1409, a glutaramic acid derivative with competitive cholecystokinin-antagonistic activity, was administered IP and evaluated in comparison with proglumide (the model CCK-receptor antagonist), gabexate (protease inhibitor) and PGE2 (cytoprotective) on two different models of experimental pancreatitis. Acute pancreat...

journal_title：Peptides

authors： Makovec F,Bani M,Cereda R,Chistè R,Revel L,Rovati LC,Setnikar I,Rovati LA

更新日期：1986-11-01 00:00:00

abstract：:The ability of acute exercise to stimulate appetite and food intake depends on intensity, duration, and agouti-related protein (AGRP) levels. Fasting, as well as any negative energy balance, has been reported to increase AGRP expression in the arcuate nucleus (ARC) of the hypothalamus and other extra-hypothalamic tiss...

journal_title：Peptides

authors： Ghanbari-Niaki A,Nabatchian S,Hedayati M

更新日期：2007-05-01 00:00:00

abstract：:Purified mast cell carboxypeptidase cleaved the C-terminal leucines from Leu5-enkephalin (Leu-ENK), neurotensin (NT), and kinetensin (KT), with Km values of 36, 16, and 15 microM, and kcat values of 44, 51, and 53 s-1, respectively. To better predict potential in vivo hydrolysis products generated by mast cell proteas...

journal_title：Peptides

authors： Goldstein SM,Leong J,Bunnett NW

更新日期：1991-09-01 00:00:00

abstract：:In this Festschrift, I discuss the career and guiding principles to which Abba J. Kastin has adhered during the last 20 years we worked together. I briefly describe the history of our joint laboratory group, the context of studies of peptide permeation across the blood-brain barrier (BBB), and newer developments in th...

journal_title：Peptides

authors： Pan W

更新日期：2015-10-01 00:00:00

abstract：:The effect of proadrenomedullin N-terminal 20 peptide (PAMP) on the proliferative activity of rat zona glomerulosa (ZG) cells has been investigated. Dispersed rat ZG cells were cultured in vitro for 24 h and then exposed to PAMP for an additional 24 h, and the proliferation rate was assessed by the 5-bromo-2'-deoxyuri...

journal_title：Peptides

authors： Rebuffat P,Gottardo L,Malendowicz LK,Neri G,Nussdorfer GG

更新日期：2001-11-01 00:00:00

abstract：:Urinary tract infections (UTI) are important health problems and predisposing causes of UTI are not entirely known. Neuro-immune interactions play an important role in human health and disease. Capsaicin-sensitive sensory nerves which in nerve bladder extensively regulate immune system through neuropeptides such as su...

journal_title：Peptides

authors： Altuntaş SÇ,Ipekçi T,Yakupoğlu G,Erin N

更新日期：2014-06-01 00:00:00

abstract：:Previous reports have demonstrated that systemic injection of cholecystokinin (CCK) in rats produces dose-related decreases in food intake, increases in neurohypophyseal secretion of oxytocin (OT), and decreases in gastric emptying. The present studies determined whether systemic injection of bombesin (BBS), another p...

journal_title：Peptides

authors： Verbalis JG,McCann MJ,Stricker EM

更新日期：1988-11-01 00:00:00

abstract：:We recently discovered that vascular responsiveness to adrenomedullin (AM), a vasoactive hormone, decreases after hemorrhage, which is markedly improved by the addition of its binding protein AMBP-1. One obstacle hampering the development of AM/AMBP-1 as resuscitation agents in trauma victims is the potential immunoge...

journal_title：Peptides

authors： Wu R,Dong W,Qiang X,Ji Y,Cui T,Yang J,Zhou M,Blau S,Marini CP,Ravikumar TS,Wang P

更新日期：2008-07-01 00:00:00

abstract：:Intracerebroventricular (ICV) bombesin increases grooming and decreases food intake in rats. We examined tolerance to these effects by administering a daily injection of either saline or 25 ng bombesin to rats for 8 days via lateral ventricular cannulas. Food intake and grooming were monitored. After 8 days bombesin n...

journal_title：Peptides

authors： Corwin RL,Corp ES,Gibbs J,Smith GP

更新日期：1992-11-01 00:00:00

abstract：:STKR is a neurokinin receptor derived from the stable fly, Stomoxys calcitrans. Insect tachykinin-related peptides, also referred to as "insectatachykinins", produce dose-dependent calcium and cyclic AMP responses in cultured Drosophila melanogaster Schneider 2 (S2) cells that were stably transfected with the cloned S...

journal_title：Peptides

authors： Poels J,Nachman RJ,Akerman KE,Oonk HB,Guerrero F,De Loof A,Janecka AE,Torfs H,Vanden Broeck J

更新日期：2005-01-01 00:00:00

abstract：:Tachykinins are thought to be involved in extrinsic control of motility in the gastrointestinal tract. Using the isolated perfused porcine antrum with intact vagal innervation, we studied the effects of substance P, neurokinin A and capsaicin infusion, and electrical stimulation of the vagus nerves on antral motility ...

journal_title：Peptides

authors： Schmidt PT,Rasmussen TN,Holst JJ

更新日期：1997-01-01 00:00:00

abstract：:There have been few reports on the effects of the brain-gut peptide motilin on the central nervous system (CNS). We administered motilin intracerebroventricularly to mice and investigated the effect of motilin on anxiety using an elevated plus-maze. Motilin produced a significant decrease in anxiety with an inverted U...

journal_title：Peptides

authors： Momose K,Inui A,Asakawa A,Ueno N,Nakajima M,Kasuga M

更新日期：1998-01-01 00:00:00

abstract：:Native peptides can be regarded as surrogate markers for protease activity in biological samples. Analysis of peptides by peptidomics allows to monitor protease activity in vivo and to describe the influence of protease inhibition. To elucidate the potential of peptides as markers for in vivo protease inhibition we an...

journal_title：Peptides

authors： Tammen H,Hess R,Rose H,Wienen W,Jost M

更新日期：2008-12-01 00:00:00

abstract：:Leptin, a hormone secreted by the adipocytes and involved in feeding and energy balance control, has been proposed to modulate alcohol craving in mice and humans. This study evaluated whether leptin modulates alcohol intake in Marchigian Sardinian alcohol-preferring (msP) rats. Rats were offered 10% ethanol either 2h ...

journal_title：Peptides

authors： Polidori C,Luciani F,Fedeli A,Geary N,Massi M

更新日期：2003-09-01 00:00:00

abstract：:Bradykinin-potentiating peptides (BPPs) are an important group of toxins present in Lachesis muta rhombeata venom. They act directly at renin-angiotensin-aldosterone system, through the inhibition of angiotensin-converting enzyme (ACE). This action may contribute to the hypotensive shock observed during the envenoming...

journal_title：Peptides

authors： Pinheiro-Júnior EL,Boldrini-França J,de Campos Araújo LMP,Santos-Filho NA,Bendhack LM,Cilli EM,Arantes EC

更新日期：2018-04-01 00:00:00

abstract：:Sex pheromone biosynthesis in many moth species is controlled by a cerebral neuropeptide, termed pheromone biosynthesis activating neuropeptide (PBAN). PBAN is a 33 amino acid C-terminally amidated neuropeptide that is produced by neuroendocrine cells of the subesophageal ganglion (SEG). Studies of the regulation of s...

journal_title：Peptides

authors： Altstein M

更新日期：2004-09-01 00:00:00

abstract：:This study determined the long-term influence of prenatal nicotine exposure (PN) on blood pressure and vascular functions in the aged offspring rats. PN did not affect body weight and plasma adrenocorticotropic hormone level; however, it significantly reduced plasma angiotensin I and angiotensin II in both sexes. Syst...

journal_title：Peptides

authors： Tao H,Rui C,Zheng J,Tang J,Wu L,Shi A,Chen N,He R,Wu C,Li J,Yin X,Zhang P,Zhu Z,Tao J,Xiao J,Mao C,Xu Z

更新日期：2013-06-01 00:00:00

abstract：:The present study demonstrates the occurrence of substance P (SP)- and calcitonin gene related peptide (CGRP)-immunoreactive nerve fibres in bone, bone marrow, periosteum, synovial membrane and soft tissues adjacent to the bone. The distribution pattern of the two types of nerves was similar, although the CGRP-positiv...

journal_title：Peptides

authors： Bjurholm A,Kreicbergs A,Brodin E,Schultzberg M

更新日期：1988-01-01 00:00:00

abstract：:The UII and urotensin II-related peptide (URP) genes belong to the same superfamily as the somatostatin gene. It has been previously shown that somatostatin activates the UII-receptor (UTR). In contrast, the possible interaction between UII and URP and somatostatin receptors has remained scarcely analyzed. Herein, we ...

journal_title：Peptides

authors： Malagon MM,Molina M,Gahete MD,Duran-Prado M,Martinez-Fuentes AJ,Alcain FJ,Tonon MC,Leprince J,Vaudry H,Castaño JP,Vazquez-Martinez R

更新日期：2008-05-01 00:00:00

abstract：:The effect of vasoactive intestinal peptide (VIP) on the nerve-stimulated contraction, tissue oxygenation, lipid peroxidation and antioxidant enzymes activities-superoxide dismutase and catalase was investigated in the rat gastrocnemius muscle exposed to 4 h ischemia-4hr reperfusion. Ischemia caused significant decrea...

journal_title：Peptides

authors： Tunçel N,Erden S,Uzuner K,Altiokka G,Tunçel M

更新日期：1997-01-01 00:00:00

abstract：:Bombesin (BBS) at doses of 0.1, 1.0, 10.0 and 100.0 nM stimulated chemiluminescence (CL) production by phagocytic cells (monocytes, macrophages and polymorphonuclear leucocytes) in mice in the presence of ZAP (opsonized zymosan particles containing luminol). These data suggest that BBS increased the phagocytic functio...

journal_title：Peptides

authors： Jin GF,Guo YS,Smith ER,Houston CW

更新日期：1990-03-01 00:00:00

abstract：:The role of muscarinic receptor subtype(s) in the control of gastric phase III contractions and motilin release was determined in dogs. Pirenzepine (226 nmol/kg/h) shortened the phase III cycle, causing an early increase in plasma motilin concentrations. Both AF-DX116BS and 4-DAMP inhibited the occurrence of spontaneo...

journal_title：Peptides

authors： Yamada T,Mizumoto A,Satoh M,Haga N,Itoh Z

更新日期：1997-01-01 00:00:00

abstract：:We show here that crotamine, a polypeptide from the South American rattlesnake venom with cell penetrating and selective anti-fungal and anti-tumoral properties, presents a potent anti-plasmodial activity in culture. Crotamine inhibits the development of the Plasmodium falciparum parasites in a dose-dependent manner [...

journal_title：Peptides

authors： El Chamy Maluf S,Dal Mas C,Oliveira EB,Melo PM,Carmona AK,Gazarini ML,Hayashi MA

更新日期：2016-04-01 00:00:00

abstract：:Unilateral intracerebroventricular (ICV) injections of a high dose of CCK7 have been reported to elicit barrel rotations accompanied by contralateral postural asymmetry; there was no spontaneous locomotor activity other than barrel rolling. The aim of the present study was to investigate the effects of lower doses of ...

journal_title：Peptides

authors： Morency MA,Ross GM,Hesketh D,Mishra RK

更新日期：1987-11-01 00:00:00

abstract：:Antimicrobial peptides (AMPs) are believed to be a promising class of antimicrobial agents against bacteria and fungi. To promote the clinical use of AMPs, their antimicrobial activity and susceptibility to protease degradation should be further improved. The antimicrobial peptide Jelleine-I was originally isolated fr...

journal_title：Peptides

authors： Jia F,Zhang Y,Wang J,Peng J,Zhao P,Zhang L,Yao H,Ni J,Wang K

更新日期：2019-02-01 00:00:00

abstract：:Neurotensin (NT) is a tridecapeptide (less than Glu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH). It has been suggested that the naturally occurring neurotensin in (Gln4)-NT and that it can be hydrolysed to (Glu4)-NT during extraction. The aim of the present study was to determine whether the neurotensin found ...

journal_title：Peptides

authors： Theodorsson-Norheim E

更新日期：1983-07-01 00:00:00

abstract：:Salusins originally identified using bioinformatics analyses have been shown to act on the cardiovascular and endocrine systems. Although the hypotensive activity of salusin-alpha is limited, it exerts a significant anti-atherosclerotic effect via suppression of foam cell formation in human monocyte-derived macrophage...

journal_title：Peptides

authors： Sato K,Koyama T,Shichiri M

更新日期：2008-12-01 00:00:00

abstract：:For clinical use, it is essential to develop potent endomorphin (EM) analogs with reduced antinociceptive tolerance. In the present study, the antinociceptive activities and tolerance development of four potent EM-1 analogs with C-terminal oligoarginine-conjugation was evaluated and compared in the radiant heat paw wi...

journal_title：Peptides

authors： Yuan BY,Liu WZ,Wang XF,Zhang YZ,Yang DJ,Wang CL

更新日期：2018-08-01 00:00:00

abstract：:Cholecystokinin induces a reduction in exploratory behaviors which could reflect an underlying behavioral state of either satiety or malaise. To investigate these alternative hypotheses, the effects of CCK were compared to the effects of (a) consumption of an extra quantity of palatable food, of (b) bombesin at doses ...

journal_title：Peptides

authors： Crawley JN

更新日期：1983-07-01 00:00:00