Angiotensin II-mediated vascular changes in aged offspring rats exposed to perinatal nicotine.

abstract：:Antimicrobial peptides produced by multicellular organisms protect against pathogenic microorganisms, whereas such peptides produced by bacteria provide an ecological advantage over competitors. Certain antimicrobial peptides of metazoan origin are also toxic to eukaryotic cells, with preference for a variety of cance...

journal_title：Peptides

authors： Sand SL,Oppegård C,Ohara S,Iijima T,Naderi S,Blomhoff HK,Nissen-Meyer J,Sand O

更新日期：2010-07-01 00:00:00

abstract：:The effects of intracerebroventricular (ICV) and intravenous injections of bombesin (BBS) on food intake were investigated in turkeys. Adult turkey hens were injected ICV with 50 to 1000 ng of BBS. In addition, the effect of pretreatment with the BBS antagonist [d-Arg1, D-Phe5, D-Trp7,9, Leu11]-substance P was investi...

journal_title：Peptides

authors： Denbow DM

更新日期：1989-03-01 00:00:00

abstract：:The role of central neuropeptide Y (NPY) in the cardiovascular response to social stress was evaluated in freely moving rats using telemetry. In unstressed rats, intracerebroventricular (ICV) administration of NPY and the selective Y1 receptor agonist [Leu31, Pro34]-NPY decreased blood pressure and heart rate, while t...

journal_title：Peptides

authors： Klemfuss H,Southerland S,Britton KT

更新日期：1998-01-01 00:00:00

abstract：:Peptides of the short neuropeptide F (sNPF) family have been shown to modulate feeding behavior in a wide variety of insect species. While these peptides stimulate feeding and food-searching behavior in Drosophila melanogaster and Apis mellifera, an opposite effect has recently been demonstrated in the desert locust, ...

journal_title：Peptides

authors： Dillen S,Verdonck R,Zels S,Van Wielendaele P,Vanden Broeck J

更新日期：2014-03-01 00:00:00

abstract：:Endomorphin1-ol (Tyr-Pro-Trp-Phe-ol, EM1-ol) and endomorphin2-ol (Tyr-Pro-Phe-Phe-ol, EM2-ol), with C-terminal alcohol (-ol) containing, have been shown to exhibit higher affinity and lower intrinsic efficacy in vitro than endomorphins. In the present study, in order to investigate the alterations of systemic hemodyna...

journal_title：Peptides

authors： Yu Y,Wang CL,Cui Y,Fan YZ,Liu J,Shao X,Liu HM,Wang R

更新日期：2006-01-01 00:00:00

abstract：:Crustacean hyperglycemic hormone (CHH) not only plays an important role in the modulation of hemolymph glucose level but also functions in other biological events including molting, reproduction and stress response. Of the six CHHs characterized in Marsupenaeus japonicus, an expression system for recombinant Pej-SGP-V...

journal_title：Peptides

authors： Nagai C,Asazuma H,Nagata S,Ohira T,Nagasawa H

更新日期：2009-03-01 00:00:00

abstract：:The localization of CCK8-, bombesin- and VIP-like immunoreactivities in the myenteric plexus of the guinea pig small intestine has been studied by radioimmunoassay of extracts of longitudinal muscle strips obtained with and without adherent myenteric plexus; concentrations were compared with those in other regions of ...

journal_title：Peptides

authors： Hutchison JB,Dimaline R,Dockray GJ

更新日期：1981-04-01 00:00:00

abstract：:Although many studies have demonstrated the action of motilin on migrating motor complex by using human subjects and relatively large animals, the precise physiological mechanisms of motilin remain obscure. One reason for the lack of progress in this research field is that large animals are generally not suitable for ...

journal_title：Peptides

authors： Tsutsui C,Kajihara K,Yanaka T,Sakata I,Itoh Z,Oda S,Sakai T

更新日期：2009-02-01 00:00:00

abstract：:We examined the expressions of the prepro-orexin gene in the lateral hypothalamic area (LHA), the genes of the neuropeptide Y (NPY) and proopiomelanocortin (POMC) in the arcuate nucleus (ARC), the orexin type 1 receptor (OX1R) gene in the ventromedial hypothalamic nucleus (VMH) and the orexin type 2 receptor (OX2R) ge...

journal_title：Peptides

authors： Yamamoto Y,Ueta Y,Yamashita H,Asayama K,Shirahata A

更新日期：2002-09-01 00:00:00

abstract：:Neuropeptide Y (NPY) induces feeding in previously satiated animals after injection into the hypothalamus, especially the perifornical region (PFH). NPY also appears to have rewarding properties as evidenced by its ability to produce a conditioned place preference following injection into the nucleus accumbens (N.Acc)...

journal_title：Peptides

authors： Brown CM,Fletcher PJ,Coscina DV

更新日期：1998-01-01 00:00:00

abstract：:Bradykinin (BK) has been proposed as the principal mediator of hypersensitivity reactions (HSR) in patients dialyzed using negatively charged membranes and concomitantly treated with angiotensin-converting enzyme (ACE) inhibitors. We investigated the metabolism of exogenous BK added to the sera of 13 patients dialyzed...

journal_title：Peptides

authors： Blais C Jr,Marc-Aurèle J,Simmons WH,Loute G,Thibault P,Skidgel RA,Adam A

更新日期：1999-01-01 00:00:00

abstract：:Four potent angiotensin converting enzyme (ACE) inhibitory peptides, IY, RIY, VW and VWIS, were isolated from subtilisin digest of rapeseed protein. Among them RIY and VWIS are new peptides with IC(50) 28 and 30 microM, respectively. All isolated peptides lowered blood pressure of spontaneously hypertensive rats (SHR)...

journal_title：Peptides

authors： Marczak ED,Usui H,Fujita H,Yang Y,Yokoo M,Lipkowski AW,Yoshikawa M

更新日期：2003-06-01 00:00:00

abstract：:The presence of human melanin-concentrating hormone (MCH) was studied in the human brain by radioimmunoassay and immunocytochemistry. Immunoreactive MCH concentrations in the human brain ranged from 0.07 to 19.7 pmol/g wet weight. High performance liquid chromatography of the hypothalamus showed a large immunoreactive...

journal_title：Peptides

authors： Mouri T,Takahashi K,Kawauchi H,Sone M,Totsune K,Murakami O,Itoi K,Ohneda M,Sasano H,Sasano N

更新日期：1993-05-01 00:00:00

abstract：:Japonicin-1 (FFPIGVFCKIFKTC) and japonicin-2 (FGLPMLSILPKALCILLKRKC), two peptides with differential growth-inhibitory activity against the Gram-negative bacterium, Escherichia coli and the Gram-positive bacterium Staphylococcus aureus, were isolated from an extract of the skin of the Japanese brown frog Rana japonica...

journal_title：Peptides

authors： Isaacson T,Soto A,Iwamuro S,Knoop FC,Conlon JM

更新日期：2002-03-01 00:00:00

abstract：:The peptide IIAEK derived from beta-lactoglobulin has a hypocholesterolemic activity greater than that of beta-sitosterol. To create food proteins with multiple copies of this valuable peptide sequence, we introduced tandem multimers of the nucleotide sequence encoding the peptide into DNA regions corresponding to the...

journal_title：Peptides

authors： Prak K,Maruyama Y,Maruyama N,Utsumi S

更新日期：2006-06-01 00:00:00

abstract：:The rat central and peripheral nervous system contains a widespread distribution of BPP-like immunoreactive neurons. Some of these neurons coexist with a catecholamine, probably mostly NE. This peptide appears to be releaseable by nerve stimulation. Catecholamine releasing agents such as reserpine do not appear to dep...

journal_title：Peptides

authors： Jacobowitz DM,Olschowka JA

更新日期：1982-05-01 00:00:00

abstract：:We show here that crotamine, a polypeptide from the South American rattlesnake venom with cell penetrating and selective anti-fungal and anti-tumoral properties, presents a potent anti-plasmodial activity in culture. Crotamine inhibits the development of the Plasmodium falciparum parasites in a dose-dependent manner [...

journal_title：Peptides

authors： El Chamy Maluf S,Dal Mas C,Oliveira EB,Melo PM,Carmona AK,Gazarini ML,Hayashi MA

更新日期：2016-04-01 00:00:00

abstract：:The effects of amiloride on ANF binding and ANF stimulation of cGMP were evaluated in rat glomeruli. Amiloride increased ANF binding to whole glomeruli and to glomerular membrane preparations. In contrast, amiloride enhanced ANF-stimulated cGMP accumulation only at 37 degrees C in whole glomeruli, but not at 4 degrees...

journal_title：Peptides

authors： Iwata T,Hardee E,Frohlich ED,Cole FE

更新日期：1989-05-01 00:00:00

abstract：:In the rodent cerebellum, PACAP is expressed by Purkinje neurons and PAC1 receptors are present on granule cells during both the development period and in adulthood. Treatment of granule neurons with PACAP inhibits proliferation, slows migration, promotes survival and induces differentiation. PACAP also protects cereb...

journal_title：Peptides

authors： Botia B,Basille M,Allais A,Raoult E,Falluel-Morel A,Galas L,Jolivel V,Wurtz O,Komuro H,Fournier A,Vaudry H,Burel D,Gonzalez BJ,Vaudry D

更新日期：2007-09-01 00:00:00

abstract：:We studied the expression of the osteogenic and antinociceptive C-terminal histone H4-related peptide fragments, H4-(89-102) (OGP) and H4-(86-100), respectively, within various rat tissues and isolated alveolar macrophages (AM) by radioimmunoassay (RIA). OGP was located mainly within the bone marrow, spleen, thymus, a...

journal_title：Peptides

authors： Poirier R,Lemaire I,Dumont M,Leduc N,Le HT,Lemaire S

更新日期：2005-08-01 00:00:00

abstract：:The goal of our study was to explore the effect of social isolation stress of varying durations on the plasma oxytocin (OT), messenger ribonucleic acid (mRNA) for oxytocin receptor (OTR), plasma arginine vasopressin (AVP) and mRNA for V1a receptor of AVP (V1aR) expression in the hypothalamus and heart of socially mono...

journal_title：Peptides

authors： Pournajafi-Nazarloo H,Kenkel W,Mohsenpour SR,Sanzenbacher L,Saadat H,Partoo L,Yee J,Azizi F,Carter CS

更新日期：2013-05-01 00:00:00

abstract：:The teleost salmon calcitonin (sCT), but not mammalian CT, shows similar biologic actions in the skeletal muscle as amylin and calcitonin gene-related peptide (CGRP). The peptides have also been shown to reduce food intake in rams. Because sCT, but not amylin, binds irreversibly to amylin binding sites, the aim of the...

journal_title：Peptides

authors： Lutz TA,Tschudy S,Rushing PA,Scharrer E

更新日期：2000-02-01 00:00:00

abstract：:The effects of dipeptide cyclo-[His-Pro] (CHP), known to participate in the appetite behavior and food intake control, have been investigated using PC12 cells in culture as model system. We found that only in the presence of experimental conditions that cause cellular stress the cyclic dipeptide affect cellular prolif...

journal_title：Peptides

authors： Minelli A,Bellezza I,Grottelli S,Pinnen F,Brunetti L,Vacca M

更新日期：2006-01-01 00:00:00

abstract：:Dissociated neurointermediate lobe cells (75%) bound [biotinyl-Ser1]corticotropin releasing hormone (bio-CRH) and secreted adrenocorticotropin [ACTH(25-39)] in a reverse hemolytic plaque assay (RHPA). The bio-CRH was rapidly internalized (less than 1 min) in vesicles and scattered vacuoles. Plaque percentages increase...

journal_title：Peptides

authors： Childs GV

更新日期：1990-07-01 00:00:00

abstract：:Amylin can evoke insulin resistance by antagonizing insulin in a non-competitive manner. Here, we investigated the glycogenolytic effect of amylin in isolated skeletal muscle and compared it to the effects of a calcitonin gene-related peptide (CGRP). Amylin alone had no statistically significant effect on glucose tran...

journal_title：Peptides

authors： Abaffy T,Cooper GJ

更新日期：2004-12-01 00:00:00

abstract：:Peptic digestion of bovine hemoglobin at low degree of hydrolysis yields an intermediate peptide fraction exhibiting antibacterial activity against Micrococcus luteus A270, Listeria innocua, Escherichia coli and Salmonella enteritidis after separation by reversed-phase HPLC. From this fraction a pure peptide was isola...

journal_title：Peptides

authors： Daoud R,Dubois V,Bors-Dodita L,Nedjar-Arroume N,Krier F,Chihib NE,Mary P,Kouach M,Briand G,Guillochon D

更新日期：2005-05-01 00:00:00

abstract：:Mate attraction in Aplysia involves the long-distance water-borne protein pheromones attractin, enticin, and temptin which are released during egg-laying. Other water-borne pheromones are predicted to act in concert with attractin, enticin, and temptin, but their identities were unknown. We recently identified a highl...

journal_title：Peptides

authors： Cummins SF,Nichols AE,Warso CJ,Nagle GT

更新日期：2005-03-01 00:00:00

abstract：:Beta-amyloid (Aβ) peptides are secreted from neurons, resulting in extracellular accumulation of Aβ and neurodegeneration of Alzheimer's disease. Because neuronal secretion is fundamental for the release of neurotransmitters, this study assessed the hypothesis that Aβ undergoes co-release with neurotransmitters. Model...

journal_title：Peptides

authors： Toneff T,Funkelstein L,Mosier C,Abagyan A,Ziegler M,Hook V

更新日期：2013-08-01 00:00:00

abstract：:Three neurotensin (NT) receptors have been cloned to date, two of which, NTS1 and NTS2, belong to the family of seven transmembrane domain receptors coupled to G proteins (GPCRs). NTS1 and NTS2 may activate multiple signal transduction pathways, involving several G proteins. However, whereas NT acts as an agonist towa...

journal_title：Peptides

authors： Pelaprat D

更新日期：2006-10-01 00:00:00

abstract：:In order to elucidate the relationship between secretory pathway and processing for precursor molecule of peptide hormones, we performed immunoelectron microscopic studies to localize POMC-derived peptides in mouse cultured L cells (fibroblasts without secretory granules) and in mouse AtT20 cells (ACTH secreting pitui...

journal_title：Peptides

authors： Osamura RY,Suemizu Y,Yoshimura S,Hori S,Inada K,Watanabe K,Nakai Y,Imura H

更新日期：1991-05-01 00:00:00