Conditioned medium from a clonal Rous sarcoma virus transformed cerebellar cell line induces process extension in glial lines.

abstract：:The localization of the two Ca-activated extralysosomal proteases m-calpain and mu-calpain in the eye of the adult rabbit was examined by immunohistochemistry, using poly- and monoclonal antibodies against the corresponding rabbit antigens. Immunoreactivity against the two forms of calpains was observed in the epithel...

journal_title：Brain research

authors： Persson H,Kawashima S,Karlsson JO

更新日期：1993-05-21 00:00:00

abstract：:Chick pineal cells contain a circadian oscillator that derives rhythmic synthesis and secretion of melatonin even in dispersed cell culture. Here, we demonstrate that the mRNA encoding tryptophan hydroxylase (TPH), the first enzyme in the melatonin synthetic pathway, is expressed rhythmically under the control of the ...

journal_title：Brain research

authors： Green CB,Besharse JC,Zatz M

更新日期：1996-10-28 00:00:00

abstract：:Aggression is a major source of social stress with negative effects on health and well-being, yet limited information is known about the molecular mechanisms mediating aggressive behavior in swine. Ractopamine (RAC) is a β-adrenoreceptor agonist that enhances growth but increases aggressive behaviors in female pigs. T...

journal_title：Brain research

authors： Poletto R,Cheng HW,Meisel RL,Richert BT,Marchant-Forde JN

更新日期：2011-03-24 00:00:00

abstract：:Alterations in brain high energy phosphate compounds, using 31P-NMR (nuclear magnetic resonance) spectroscopy, were measured in vivo in young adult (3-4 months) rats following prenatal exposure to ligands acting specifically at benzodiazepine (BDZ) binding sites. The exposure induced a decrease in intracellular pH tha...

journal_title：Brain research

authors： Miranda R,Ceckler T,Guillet R,Kellogg C

更新日期：1990-01-01 00:00:00

abstract：:There is emerging evidence that increased acetylcholine levels in brain reduce anxiety. More specifically there is evidence that some of these anxiolytic effects of acetylcholine are modulated by the hippocampus. In the present study we examined the roles of the cholinergic systems in the dorsal and ventral hippocampu...

journal_title：Brain research

authors： Degroot A,Treit D

更新日期：2002-09-13 00:00:00

abstract：:In most vertebrates and several insects, melatonin (N-acetyl-5-methoxytryptamine) is synthesized enzymatically from serotonin (5-hydroxytryptamine) by the sequential action of arylalkylamine N-acetyltransferase (NAT) and hydroxyindole-O-methyltransferase (HIOMT). In the freshwater planarian Dugesia japonica, which bel...

journal_title：Brain research

authors： Itoh MT,Shinozawa T,Sumi Y

更新日期：1999-05-29 00:00:00

abstract：:Avian circadian rhythms are regulated by a multiple oscillatory system consisting of the pineal, the suprachiasmatic nucleus (SCN) and the eye. In the present study, ontogeny of circadian clock in the pineal and the SCN of chick embryo was examined using Per2 expression as a marker. A daily rhythmicity of Per2 express...

journal_title：Brain research

authors： Okabayashi N,Yasuo S,Watanabe M,Namikawa T,Ebihara S,Yoshimura T

更新日期：2003-11-14 00:00:00

abstract：:The present study has investigated the long-term changes in the organisation of the corticomotor projection to the hand in a group of subjects who had sustained a subcortical hemispheric stroke up to 15 years previously and had subsequently recovered normal or near-normal motor function. Transcranial magnetic cortical...

journal_title：Brain research

authors： Byrnes ML,Thickbroom GW,Phillips BA,Mastaglia FL

更新日期：2001-01-19 00:00:00

abstract：:In a study of the capacity of neural grafts to promote functional recovery in rats with fimbria-fornix lesions, 5 groups of rats were studied behaviourally and with acetylcholinesterase (AChE) histochemistry: (1) sham-operated controls; (2) bilateral fimbria-fornix lesions; (3) bilateral lesions plus bilateral solid e...

journal_title：Brain research

authors： Dunnett SB,Low WC,Iversen SD,Stenevi U,Björklund A

更新日期：1982-11-18 00:00:00

abstract：:The mechanism of 3,4-methylenedioxymethamphetamine (d-MDMA)-induced neurotoxicity may involve formation of toxic radical species. Endogenous defenses against toxic radical species include tissue stores of vitamin E, and thiols. We examined whether vitamin E deficiency could alter d-MDMA-induced neurotoxicity by admini...

journal_title：Brain research

authors： Johnson EA,Shvedova AA,Kisin E,O'Callaghan JP,Kommineni C,Miller DB

更新日期：2002-04-19 00:00:00

abstract：:In the central nervous system (CNS) insulin mediates a variety of effects including feeding, metabolism and cognition. The cognitive enhancing effects of insulin are proposed to be mediated through activation of insulin receptors in the hippocampus, an important integration center for learning and memory in the mammal...

journal_title：Brain research

authors： Grillo CA,Piroli GG,Hendry RM,Reagan LP

更新日期：2009-11-03 00:00:00

abstract：:Five pairs of neurosecretory cells in the subesophageal ganglion of the silkmoth Bombyx mori discharge action potentials in (near) synchrony to release a pheromone biosynthesis-activating neuropeptide (PBAN). Waveforms of compound action potentials recorded extracellularly from axonal tracts were analyzed to determine...

journal_title：Brain research

authors： Ichikawa T

更新日期：2002-03-08 00:00:00

abstract：:Microinfusions of the benzodiazepine anxiolytic midazolam into the central or basolateral amygdaloid nuclei produced different anxiolytic effects in two tests of rat 'anxiety'. Infusions into the basolateral nucleus impaired open-arm avoidance in the elevated plus-maze test, but did not impair shock-probe avoidance in...

journal_title：Brain research

authors： Pesold C,Treit D

更新日期：1995-02-13 00:00:00

abstract：:The adrenergic transmitter norepinephrine (NE) dramatically increases the prominence of only two out of the hundreds of [35S]methionine-labeled pineal proteins resolved by two-dimensional polyacrylamide gel electrophoresis (2D-PAGE). One of these regulated proteins is AIP 37/6 (37 kDa, pI approximately 6). The labelin...

journal_title：Brain research

authors： Weller JL,Jaffe H,Roseboom PH,Zylka MJ,Klein DC

更新日期：1996-03-25 00:00:00

abstract：:Male rats were treated with barbital in their drinking fluid for about 40 weeks (daily dose 200 mg/kg). The treatment was stopped on day 0 and the number of muscarinic binding sites was measured in 3 brain parts (striatum; cortex and hippocampus; medulla oblongata and midbrain) during the abstinence with labeled quinu...

journal_title：Brain research

authors： Nordberg A,Wahlström G

更新日期：1982-08-19 00:00:00

abstract：:The electrical property of delayed K+ currents (IKD) was studied in pyramidal neurones freshly isolated from the rat hippocampal CA1 region. The IKD was separated pharmacologically from other membrane currents. Activation and inactivation processes of the IKD were highly voltage-dependent in the potential range betwee...

journal_title：Brain research

authors： Oyama Y,Harata N,Akaike N

更新日期：1991-12-24 00:00:00

abstract：:Pretreatment with the alpha(2)-adrenoceptor agonist clonidine (31.25, 62.5, or 125 microg/kg, i.p.) dose-dependently reduced long-term potentiation (LTP) elicited in vivo in the occipital cortex of anesthetized rats, whereas pretreatment with the alpha(2)-adrenoceptor antagonist yohimbine (0.133, 0.4, or 1.2 mg/kg, i....

journal_title：Brain research

authors： Mondaca M,Hernández A,Pérez H,Valladares L,Sierralta W,Fernández V,Soto-Moyano R

更新日期：2004-09-24 00:00:00

abstract：:With the aim of determining a possible role of the entorhinal cortex (EC) in the processing of olfactory information, its electrical activity was recorded during different types of odour sampling behaviour. The EC spontaneous field potentials (EEGs) were related to those recorded simultaneously from the more rostrally...

journal_title：Brain research

authors： Boeijinga PH,Lopes da Silva FH

更新日期：1989-01-30 00:00:00

abstract：:Treated carbon fiber electrodes were used with differential normal pulse voltammetry (DNPV) for in vivo determination of the relative participation of uric acid (UA) to peak 3 derived between 250-300 mV in the dorsal horn of the spinal cord of anesthetized rats. In vitro, treated carbon fiber electrodes respond linear...

journal_title：Brain research

authors： Rivot JP,Noret E,Ory-Lavollée L,Besson JM

更新日期：1987-09-01 00:00:00

abstract：:The current experiment aimed to explore age differences in brain activity associated with successful memory retrieval in older adults with different levels of executive functioning, at different levels of task demand. Memory performance and fMRI activity during a recognition task were compared between a young group an...

journal_title：Brain research

authors： Angel L,Bastin C,Genon S,Salmon E,Fay S,Balteau E,Maquet P,Luxen A,Isingrini M,Collette F

更新日期：2016-01-15 00:00:00

abstract：:The organization of motor responses in the orbicularis oris muscle following the delivery of punctate mechanical inputs to vermilion skin of the lips was studied in a group of young infants, school-age children, and adults during periods of voluntary lip muscle activation. A specially designed multi-point array skin c...

journal_title：Brain research

authors： Barlow SM,Finan DS,Bradford PT,Andreatta RD

更新日期：1993-10-01 00:00:00

abstract：:Immunohistochemical staining with mouse monoclonal antibody R24 recognizing the ganglioside GD3 was used to study the distribution of GD3 in the human brain. Positive staining was primarily found in the surrounding neuropil of many neuronal groups in the brainstem and spinal cord, cerebellum, retina and dentate gyrus ...

journal_title：Brain research

authors： Graus F,Cordon-Cardo C,Houghton AN,Melamed MR,Old LJ

更新日期：1984-12-17 00:00:00

abstract：:Previous research has suggested the potential involvement of the hypothalamic-pituitary-adrenal (HPA) axis in psychostimulant reinforcement. In particular, we have found significant correlations between electric footshock-induced increases in plasma corticosterone and the acquisition, or lack thereof, of intravenous c...

journal_title：Brain research

authors： Goeders NE,Guerin GF

更新日期：1996-05-25 00:00:00

abstract：:Transplantation of fetal substantia nigra into the brain can alleviate some of the manifestations of animal models of Parkinson's disease. The purpose of the present experiment was to determine the optimal embryonic donor age for solid tissue substantia nigra grafts. Rats with unilateral substantia nigra lesions were ...

journal_title：Brain research

authors： Simonds GR,Freed WJ

更新日期：1990-10-15 00:00:00

abstract：:Using fMRI, cerebral activations were studied in 24 classically-trained keyboard performers and 12 musically unskilled control subjects. Two groups of musicians were recruited: improvising (n=12) and score-dependent (non-improvising) musicians (n=12). While listening to both familiar and unfamiliar music, subjects eit...

journal_title：Brain research

authors： Harris R,de Jong BM

更新日期：2015-10-22 00:00:00

abstract：:Beta-amyloid (Abeta) peptides, the major component of senile plaques in brains of patients with Alzheimer's disease (AD), were found in the low pH organelles (i.e. endosome/lysosome) of cultured neuronal cells. Since acidic pH values have been shown to promote the self-assembly of Abetas, which seems to be a prerequis...

journal_title：Brain research

authors： Su Y,Chang PT

更新日期：2001-03-02 00:00:00

abstract：:The effects of acetylcholine (ACh) and physostigmine (PHY) on thoracic ganglion neurons of Locusta migratoria were investigated using whole-cell and cell-attached voltage clamp. ACh activated whole-cell currents with variable amplitudes, time course and ion channel block between cells, suggesting differential expressi...

journal_title：Brain research

authors： van den Beukel I,van Kleef RG,Zwart R,Oortgiesen M

更新日期：1998-04-13 00:00:00

abstract：:In human brain, regulation of agonist binding to the D2 dopamine receptors by guanine nucleotides is different between several regions. In membranes of the anterior pituitary lobe, agonist binding is fully sensitive to GTP or Gpp(NH)p, whereas it is resistant in membranes of globus pallidus. Both guanine nucleotide-se...

journal_title：Brain research

authors： De Keyser J,Walraevens H,De Backer JP,Ebinger G,Vauquelin G

更新日期：1989-04-10 00:00:00

abstract：:An inhibitor of tissue plasminogen activator (tPA) was tested for its effects on the rapid kindling induced by a series of afterdischarges (ADs) triggered in hippocampus over a 3-h period. Rats injected with vehicle prior to the session had prolonged ADs in tests carried out 10 days later. This was not the case for an...

journal_title：Brain research

authors： Hoffman KB,Hwee V,Larson J,Lynch G

更新日期：2000-04-07 00:00:00

abstract：:We examined whether there are the neurotransmitter candidate amino acid L-proline containing neurons localized in the rat brain. Antibodies against L-proline conjugated with rabbit serum albumin were raised in a rabbit and purified with affinity chromatography. Strong L-proline-like immunoreactivity was confined to se...

journal_title：Brain research

authors： Takemoto Y,Semba R

更新日期：2006-02-16 00:00:00