Induction of the alcohol-metabolizing pathway in the nematode Panagrellus redivivus: phenotypic effects.

Abstract:

:Panagrellus redivivus when placed in 7% ethanol or methanol becomes immobile. After 1 hr the animals resume normal swimming and will grow in alcohol. The ability to recover requires ADH activity and translation, but not transcription, as determined by inhibitor studies. Recovery decreases with longer-chain alcohols, with a greater recovery for branched rather than n-alcohols. Coincident with recovery is a threefold increase in alcohol dehydrogenase and aldehyde dehydrogenase activity. A model involving posttranscriptional control of the levels of these enzymes is presented.

journal_name

Biochem Genet

journal_title

Biochemical genetics

authors

Kriger F,Burke D,Samoiloff MR

doi

10.1007/BF00484508

subject

Has Abstract

pub_date

1977-12-01 00:00:00

pages

1181-91

issue

11-12

eissn

0006-2928

issn

1573-4927

journal_volume

15

pub_type

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