Abstract:
:A new variant of hereditary hemolytic anemia in a family due to high adenosine triphosphate (ATP) is reported. The increase in ATP levels varied from 83 to 105% in the family members. Low 2,3-diphosphoglycerate levels and low 2,3-diphosphoglyceromutase activity were observed in three family members, with normal glucose-6-phosphate dehydrogenase and pyruvate kinase activity.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Bapat JP,Baxi AJdoi
10.1007/BF00504264subject
Has Abstractpub_date
1981-10-01 00:00:00pages
1017-22issue
9-10eissn
0006-2928issn
1573-4927journal_volume
19pub_type
杂志文章abstract::During a large-scale screen of a human fetal brain cDNA library, a full-length cDNA encoding a novel Rap2 interacting protein was isolated and sequenced. The cDNA is 3397bp long and has a predicted open reading frame encoding a protein of 329 aa. The predicted protein shows high homology to mouse and human RPIP8, and ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1020918411532
更新日期:2003-02-01 00:00:00
abstract::Genetic variation at three dipeptidase loci (Dip-A, Dip-B, and Dip-C) in Drosophila simulans was analyzed by starch gel electrophoresis. Dip-A was found to be polymorphic in four populations, while Dip-B and Dip-C were found to be polymorphic in one. The numbers of different alleles found at each respective locus were...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00486138
更新日期:1981-02-01 00:00:00
abstract::This haplotype-based case-control study investigated whether the aldosterone synthase gene (CYP11B2) might be implicated in the pathogenesis of essential hypertension in Yi (226 individuals) and Hani (296 individuals) minorities of China. Four tag SNPs (rs4536, rs4545, rs3097, and rs3802230) and the K173R polymorphism...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-010-9393-5
更新日期:2011-02-01 00:00:00
abstract::Electrophoretic variation of sorbitol dehydrogenase has been found in Mus musculus; the SDH-1 A phenotype migrates further toward the cathode under the conditions used than the SDH-1B phenotype. Mice with the SDH-1B phenotype have enzyme activity reduced to 25% of that found in mice with the SDH-1A phenotype, but no d...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00498928
更新日期:1983-08-01 00:00:00
abstract::Non-alcoholic fatty liver disease is one of the main causes of chronic liver disease and therefore is currently considered a major public health problem. Sirtuin 1 (SIRT1) is an NAD-dependent deacetylase enzyme that contributes in the regulation of metabolic processes and protects against lipid accumulation in hepatoc...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-019-09905-5
更新日期:2019-08-01 00:00:00
abstract::Glycogen synthase, which catalyzes the synthesis of glycogen, is especially important for Old World (Pteropodidae) and New World (Phyllostomidae) fruit bats that ingest high-carbohydrate diets. Glycogen synthase 1, encoded by the Gys1 gene, is the glycogen synthase isozyme that functions in muscles. To determine wheth...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-014-9659-4
更新日期:2014-10-01 00:00:00
abstract::The aldox-2 locus in Drosophila melanogaster has been shown to affect differentially three molybdoenzymes, aldehyde oxidase, pyridoxal oxidase, and xanthine dehydrogenase. These effects are most obvious at times surrounding the pupal-adult boundary, when the normal organism accumulates large amounts of these enzymes i...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499002
更新日期:1986-10-01 00:00:00
abstract::Variations at three flight-related enzyme loci, delta-glycerophosphate dehydrogenase (delta-Gpdh), glucose-6-phosphate dehydrogenase (G6pd), and phosphoglucomutase (Pgm), of Epiphyas postvittana (Walker) moths were investigated using starch gel electrophoresis. Among the three enzyme loci, delta-Gpdh and G6pd were fou...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554142
更新日期:1991-08-01 00:00:00
abstract::An Italian organophosphate-resistant strain of Culex pipiens (Lucca) was found to be polymorphic for elevated and nonelevated esterases. Selection for high esterase activity produced a strain homozygous for elevated esterases A2 and B2. Selection for low activity produced a strain homozygous for nonelevated esterases,...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02426878
更新日期:1993-12-01 00:00:00
abstract::The autoregulation of testicular luteinizing hormone (LH) receptors was studied in hypogonadal (hpg/hpg) and normal mice. The basal concentration of LH receptors was more than three-fold higher in hpg/hpg than in normal mice. After injection of hCG, hpg/hpg mice showed a decrease in LH receptor levels which was not ob...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484511
更新日期:1984-06-01 00:00:00
abstract::Genetic analysis of a polymorphic tissue esterase revealed a new locus (Est-6) with two alleles (Est-6a and Est-6b) on linkage group VI of the rabbit. Est-6 is closely linked to the Est-1,2,4 cluster. Esterase of Est-6 is found in many organs, particularly in liver and small intestine, but not in erythrocytes and seru...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554543
更新日期:1987-06-01 00:00:00
abstract::Fifty-six sequences encoding the pina protein were characterized from three species or subspecies of einkorn wheat. These sequences contained 1,595 nucleotides, including 1,270 conserved sites, 21 single nucleotide polymorphisms (SNPs), and 16 indels. The average frequency of SNPs and indels was one out of 76.1 and 99...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-009-9239-1
更新日期:2009-06-01 00:00:00
abstract::DNA damage repair elements accumulate at DNA damage sites to form ionizing radiation-induced foci (IRIF) for damage repair. IRIF, which represent direct evidence of DNA damage response activity, which are conveniently to be observed via immunofluorescence staining. Protein ubiquitination plays an important role in ini...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-015-9707-8
更新日期:2016-04-01 00:00:00
abstract::The domesticated turkey, Meleagris gallopavo, is believed to be a single breed with several varieties whose relatedness and origins remain poorly understood. Using the mitochondrial genome sequence (GenBank accession no. EF153719) that our group first reported, we investigated the relationships among 15 of the most wi...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-015-9668-y
更新日期:2015-04-01 00:00:00
abstract::Thirteen isolates of porcine reproductive and respiratory syndrome virus (PRRSV) from different provinces of China were studied and compared with several PRRSV isolates from other countries. Phylogenetic analysis shows that all Chinese isolates of PRRSV in this study belong to the American genotype, except for one str...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-006-9039-9
更新日期:2006-10-01 00:00:00
abstract::Skeletal muscle tissues from many species of salmonid fish are known to exhibit a set of three of five isozymes for A4-type lactate dehydrogenase (L-lactate: NAD oxidoreductase, E.C. 1.1.1.27), but the genetic basis for this isozyme system has not previously been assessed. This isozyme system was purified to homogenei...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484099
更新日期:1977-08-01 00:00:00
abstract::In an attempt to find clues for the significance of the gene ordering along the eukaryotic chromosome, a system consisting of germinating conida of Neurospora crassa was studied. Thirteen enzyme activities corresponding to genes widely distributed on five chromosomes were determined in dormant and in germinating conid...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484413
更新日期:1975-12-01 00:00:00
abstract::Upland rice landraces from different villages of Mizoram, Northeast India were analyzed for seed morphology, amylose content, aromatic characteristic, seed storage protein profiling and genetic diversity. Results revealed variation in grain length, width, weight and shape. Protein profiling showed polypeptide bands ra...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-018-09901-1
更新日期:2019-06-01 00:00:00
abstract::Genetic linkage maps are valuable tools for genetic, genomic, and crop breeding studies. Several genetic linkage maps were constructed for the olive (Olea europaea L.) genome, mainly using amplified fragment length polymorphisms (AFLPs) and simple sequence repeat (SSR) markers. However, AFLPs and SSR markers were not ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-016-9721-5
更新日期:2016-06-01 00:00:00
abstract::Arylsulfatase A (ASA) activity was studied from five blood fractions, leukocytes plus platelets (LKPL), leukocytes (LK), neutrophils (N), lymphocytes (LYM), and platelets (PL). No significant difference was found among the mean ASA specific activity values for the fractions. Electrophoretic examination revealed four d...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484068
更新日期:1982-10-01 00:00:00
abstract::The highly active esterases A' and B that cannot be dissociated from OP resistance in Culex pipiens from France and California are shown to have equivalent Km values (2.1 x 10(-6) M/min/mosquito) but different turnover rates (Vm = 2.13 and 0.57 x 10(-6) M/min/mosquito, respectively) and pH for maximum activity. Both ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00504256
更新日期:1981-10-01 00:00:00
abstract::Suspicious hybrids of painted storks and milky storks were found in a Malaysian zoo. Blood of these birds was sampled on FTA cards for DNA fingerprinting. Of 44 optimized primers, 6 produced diagnostic markers that could identify hybrids. The markers were based on simple, direct PCR-generated multilocus banding patter...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-013-9607-8
更新日期:2013-10-01 00:00:00
abstract::Sequence divergence of mitochondrial COII was analyzed in 50 specimens belonging to five subspecies of Polyura eudamippus (Lepidoptera: Nymphalidae) collected from southern China. There were nine haplotypes in the 405 bp of partial COII sequence. Distribution of the five subspecies was primarily consistent with the sp...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-006-9035-0
更新日期:2006-10-01 00:00:00
abstract::To determine the genetic structure and variation of Van cats and some other cats, seven enzyme loci were examined using horizontal starch gel electrophoresis. ME bands were observed for the first time in cats. For the enzyme loci CA ( 1 ), SOD, GPI, and GOT, neither the individual Van cats nor the specimens of other c...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-011-9426-8
更新日期:2011-08-01 00:00:00
abstract::Phenol sulfotransferase (PST) catalyzes the sulfate conjugation of catechol and phenolic drugs and xenobiotic compounds. Platelets and other tissues contain at least two forms of PST, forms that have been designated the "TL" and the "TS" forms. We measured the thermal stability of platelet TS PST in blood samples from...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499627
更新日期:1984-12-01 00:00:00
abstract::This study deals with the characterization of 10 populations of M. musculus from different geographical locations in India. The genetics of Indian wild mice has been completely obscure and this is the first report on allozyme variations in the natural population. We have used a set of 24 biochemical genetic markers to...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1018781026170
更新日期:1998-08-01 00:00:00
abstract::Restriction endonuclease analyses of DNA from one Black G gamma A gamma-HPFH homozygote and four Black and one Indian G gamma A gamma-HPFH heterozygotes have identified three different HPFH types which are the result of large deletions including the delta and beta genes. Two of the types are comparable to those charac...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499284
更新日期:1984-02-01 00:00:00
abstract::Non-alcoholic fatty liver disease (NAFLD) have a high prevalence in humans in the past two decades. Here, we elucidated the functions of miR-30a-3p in the development of NAFLD and identified its potential targets. HepG-2 cells and NAFLD patients' blood samples were used in our study. Bioinformatics analysis as well as...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09971-0
更新日期:2020-10-01 00:00:00
abstract::Single-chain variable fragment (scFv) is one of the most common antibody forms. This report describes the expression of the scFv gene as a soluble protein in Origami DE3 cytoplasm. The purified scFv recognized the epidermal growth factor receptor (EGFRvIII) on the surface of MCF-7 cells. The scFv protein was purified ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-012-9506-4
更新日期:2012-08-01 00:00:00
abstract::Two alleles are encoded at the malate dehydrogenase locus in largemouth bass, Micropterus salmoides. Populations in the extreme northern areas of the range of this fish are fixed or nearly fixed for the B1 allele, whereas populations in Florida are fixed for the alternative allele, B2. The MDH-B1B1 and MDH-B2B2 alleli...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00488466
更新日期:1983-12-01 00:00:00