Linkage analyses and biochemical genetics of sorbitol dehydrogenase-1 (Sdh-1) in the mouse.

abstract：:Because alternative RNA splicing regulation in the testis is prevalent, we explored testes of Sprague-Dawley rats for existence of alternatively spliced colony-stimulating factor 1 receptor (CSF-1R) mRNA. Using RT-PCR and sequencing, we identified a variant of CSF-1R mRNA that was 284 bp shorter than the full-length C...

journal_title：Biochemical genetics

authors： Su H,Wang Y,Söder O,Hou M

更新日期：2014-06-01 00:00:00

abstract：:Panagrellus redivivus when placed in 7% ethanol or methanol becomes immobile. After 1 hr the animals resume normal swimming and will grow in alcohol. The ability to recover requires ADH activity and translation, but not transcription, as determined by inhibitor studies. Recovery decreases with longer-chain alcohols, w...

journal_title：Biochemical genetics

authors： Kriger F,Burke D,Samoiloff MR

更新日期：1977-12-01 00:00:00

abstract：:A significant challenge in epistasis detection is the huge amount of data, which leads to combinatorial explosion. This study focuses on a two-stage approach for detecting epistasis only among single nucleotide polymorphisms (SNPs) that show some marginal effect. We present this two-stage approach based on the fusion ...

journal_title：Biochemical genetics

authors： Liao Z,Zeng Q,Liao B,Li X

更新日期：2014-10-01 00:00:00

abstract：:Three new linkage groups of enzyme loci are described using Poeciliopsis monacha x P. viriosa-derived interspecific backcross hybrids. Comparison to known linkage groups of the confamilial genus Xiphophorus shows homology between Xiphophorus linkage group I and Poeciliopsis linkage group III, Xiphophorus linkage group...

journal_title：Biochemical genetics

authors： Morizot DC,Schultz RJ,Wells RS

更新日期：1990-02-01 00:00:00

abstract：:Markhors (Capra falconeri) are among the most endangered mammal species, and several conservation measures, including ex situ breeding, are implemented to prevent their extinction. We studied sequence diversity and differentiation of the first hypervariable segment of the mitochondrial DNA control region among C. f. h...

journal_title：Biochemical genetics

authors： Hammer SE,Schwammer HM,Suchentrunk F

更新日期：2008-04-01 00:00:00

abstract：:The solute carrier family 11 member 1 (SLC11A1) protein plays important roles in macrophage activation and displays pleiotropic effects on various macrophage functions, including the regulation of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and oxidative burst. Considering the important role...

journal_title：Biochemical genetics

authors： Kim EJ,Kim KM,Park SH,Kim JS,Lee WK,Cha SI,Kim CH,Kang YM,Han SB,Jung TH,Park JY

更新日期：2008-08-01 00:00:00

abstract：:Examination of eight Atlantic species of the genus Littorina by starch gel electrophoresis of purine nucleoside phosphorylase revealed extensive polymorphism within the L. saxatilis complex. In this group, four alleles have been identified. Heterozygotes are four banded, and thus, as in vertebrates, the enzyme is like...

journal_title：Biochemical genetics

authors： Knight AJ,Ward RD

更新日期：1986-06-01 00:00:00

abstract：:The highly active esterases A' and B that cannot be dissociated from OP resistance in Culex pipiens from France and California are shown to have equivalent Km values (2.1 x 10(-6) M/min/mosquito) but different turnover rates (Vm = 2.13 and 0.57 x 10(-6) M/min/mosquito, respectively) and pH for maximum activity. Both ...

journal_title：Biochemical genetics

authors： Pasteur N,Iseki A,Georghiou GP

更新日期：1981-10-01 00:00:00

abstract：:Using megagametophyte (maternal haploid) and embryo (diploid) tissues of incense-cedar seeds, the expression of one of three malate dehydrogenase (MDH) loci was found to be influenced by a second, unlinked, modifier locus. Whereas alleles of the affected structural locus are codominant, the modifier alleles show domin...

journal_title：Biochemical genetics

authors： Harry DE

更新日期：1983-06-01 00:00:00

abstract：:Single nucleotide polymorphisms (SNP) in the resistin gene (RETN) are linked to obesity and resistin levels in various populations. However, results have been inconsistent. This study aimed to investigate association between polymorphisms in the resistin gene with obesity in a homogenous Malaysian Malay population. Th...

journal_title：Biochemical genetics

authors： Apalasamy YD,Rampal S,Salim A,Moy FM,Su TT,Majid HA,Bulgiba A,Mohamed Z

更新日期：2015-06-01 00:00:00

abstract：:The stem-loop potential of a nucleic acid segment (expressed as a FONS value), decomposes into base composition-dependent and base order-dependent components. The latter, expressed as a FORS-D value, is derived by subtracting the value of the base composition-dependent component (FORS-M) from the FONS value. FORS-D an...

journal_title：Biochemical genetics

authors： Zhang CY,Wei JF,Wu JS,Xu WR,Sun X,He SH

更新日期：2008-02-01 00:00:00

abstract：:The concentration of mouse kidney histidine decarboxylase (HDC) is modulated by estrogen, testosterone, and thyroxine in a tissue-specific manner. Variation in HDC levels between strains of mice can be used to investigate the genetic regulation of enzyme structure, tissue specific expression, and induction and repress...

journal_title：Biochemical genetics

authors： Martin SA,Bulfield G

更新日期：1984-08-01 00:00:00

abstract：:Three serum transferrin phenotypes of Praomys (Mastomys) natalensis, and African rodent having a high incidence of many varieties of spontaneous neoplasms, were detected by electrophoresis and autoradiography. On electrophoresis, transferrin of Trf-K was found to be a protein that migrates slowly toward the cathode, w...

journal_title：Biochemical genetics

authors： Ootsu K,Matsumoto T,Hirano T

更新日期：1976-10-01 00:00:00

abstract：:Restriction endonuclease fragment length variations (RFLVs) were detected by using a rat cDNA probe for the bilirubin UDP-glucuronosyltransferase (UDPGT) gene between two mouse strains, 129/Sv and MOL-MIT. RFLVs of the gene were found by EcoRI and PvuII digestions. From linkage analyses of the three-point cross test u...

journal_title：Biochemical genetics

authors： Sato H,Sakai Y,Koiwai O,Watanabe T

更新日期：1992-08-01 00:00:00

abstract：:The goals of this study were to analyze the change in the global gene expression profile of exogenous human leukocyte antigen-G1 (HLA-G1) overexpressed in human embryonic stem (hES) cells and to explore the molecular mechanism by which the overexpression of HLA-G1 modifies immunologic pathways. Microarray and quantita...

journal_title：Biochemical genetics

authors： Zhu Y,Zhao S,Zhao H,Yao Y

更新日期：2012-10-01 00:00:00

abstract：:The retinal pigment epithelium (RPE) plays a key role in the maintenance of the normal functions of the retina. Tissue engineering using amniotic membrane as a substrate to culture RPE cells may provide a promising new strategy to replace damaged RPE. We established a method of culturing RPE cells over the amniotic me...

journal_title：Biochemical genetics

authors： Akrami H,Soheili ZS,Sadeghizadeh M,Khalooghi K,Ahmadieh H,Kanavi MR,Samiei S,Pakravesh J

更新日期：2011-06-01 00:00:00

abstract：:Upland rice landraces from different villages of Mizoram, Northeast India were analyzed for seed morphology, amylose content, aromatic characteristic, seed storage protein profiling and genetic diversity. Results revealed variation in grain length, width, weight and shape. Protein profiling showed polypeptide bands ra...

journal_title：Biochemical genetics

authors： Vanlalsanga,Singh YT

更新日期：2019-06-01 00:00:00

abstract：:The genetic and cytogenetic locations of the structural gene (Men) for malic enzyme have been determined. Men maps genetically between kar and ry at 51.73 +/- 0.02. Cytogenetically, Men probably lies in the proximal edge of 87D1,2, based on the results of mapping utilizing a number of deficiencies with breakpoints in ...

journal_title：Biochemical genetics

authors： Voelker RA,Ohnishi S,Langley CH,Gausz J,Gyurkovics H

更新日期：1981-06-01 00:00:00

abstract：:The ribosomal RNA cistrons of three species of trout: Salvelinus namaycush (lake trout), Salvelinus fontinalis (brook trout), and Salmo gairdneri (rainbow trout) were examined by Southern blot analysis of genomic DNA. The repeat length of the cistron of S. namaycush is 26 kb. A repeat-length polymorphism was observed ...

journal_title：Biochemical genetics

authors： Popodi EM,Greve D,Phillips RB,Wejksnora PJ

更新日期：1985-12-01 00:00:00

abstract：:Histone H1 from erythrocytes of Japanese quail was resolved in a sodium dodecyl sulfate (SDS)-polyacrylamide gel into five fractions differing in apparent molecular weights. A polymorphism of histone H1.1, H1.2, and H1.3 bands was detected among quail individuals. While some birds possessed either a high (phenotype .3...

journal_title：Biochemical genetics

authors： Pałyga J

更新日期：1991-10-01 00:00:00

abstract：:UMP synthase was characterized biochemically in dairy cattle heterozygous for a deficiency of this enzyme. Both activities comprising this bifunctional enzyme are decreased, with OMP decarboxylase more affected than orotate phosphoribosyltransferase. Immunotitration of UMP synthase activity revealed the presence of th...

journal_title：Biochemical genetics

authors： Harden KK,Robinson JL

更新日期：1987-08-01 00:00:00

abstract：:Techniques are presented to detect 23 isozyme loci in the long-lived perennial plant, ponderosa pine. Meiotically derived megagametophyte from seeds is used to examine directly the segregation of allelic variants. Approximately seven seeds were initially examined for 12 enzymes from each of 47 trees from ten stands th...

journal_title：Biochemical genetics

authors： O'Malley DM,Allendorf FW,Blake GM

更新日期：1979-04-01 00:00:00

abstract：:In this study, the geographic patterns of genetic variation of three rodent species belonging to the tribe Oryzomyini were investigated using the mitochondrial cytochrome b and nuclear IRBP genes in biomes that are undergoing degradation processes to a greater or lesser degree. The samples are from 25 collecting local...

journal_title：Biochemical genetics

authors： Miranda GB,Andrades-Miranda J,Oliveira LF,Langguth A,Mattevi MS

更新日期：2007-12-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) have a high prevalence in humans in the past two decades. Here, we elucidated the functions of miR-30a-3p in the development of NAFLD and identified its potential targets. HepG-2 cells and NAFLD patients' blood samples were used in our study. Bioinformatics analysis as well as...

journal_title：Biochemical genetics

authors： Wang DR,Wang B,Yang M,Liu ZL,Sun J,Wang Y,Sun H,Xie LJ

更新日期：2020-10-01 00:00:00

abstract：:DNA damage repair elements accumulate at DNA damage sites to form ionizing radiation-induced foci (IRIF) for damage repair. IRIF, which represent direct evidence of DNA damage response activity, which are conveniently to be observed via immunofluorescence staining. Protein ubiquitination plays an important role in ini...

journal_title：Biochemical genetics

authors： Wang D,Tian Y,Wei D,Jing Y,Niu H,Xie K,Song Y

更新日期：2016-04-01 00:00:00

abstract：:In fission yeast (Schizosaccharomyces pombe) the homologue of the mammalian SUMO-1 ubiquitin-like modifier is encoded by the pmt3 gene. A two-hybrid screen using the telomere-binding protein Taz1p as bait identified Pmt3p as an interacting factor. In vitro experiments using purified components of the fission yeast Pmt...

journal_title：Biochemical genetics

authors： Spink K,Ho JC,Tanaka K,Watts FZ,Chambers A

更新日期：2005-04-01 00:00:00

abstract：:Scirpophaga incertulas, commonly referred to as yellow stem borer, is a predominant pest of rice causing serious losses in its yield. Genetic variation among populations of Scirpophaga incertulas collected from 28 hotspot locations in India was examined using the randomly amplified polymorphic DNA-polymerase chain rea...

journal_title：Biochemical genetics

authors： Kumar LS,Sawant AS,Gupta VS,Ranjekar PK

更新日期：2001-02-01 00:00:00

abstract：:Human PQBP-1 is known to interact with triplet repeat disease gene products such as ataxin and huntingtin through their poly-glutamine (poly-Q) tracts. The poly-Q tracts show extensive variation in both the number and the configuration of repeats among species. A surface plasmon resonance assay showed clear interactio...

journal_title：Biochemical genetics

authors： Kurosaki T,Gojobori J,Ueda S

更新日期：2012-04-01 00:00:00

abstract：:The frequency distributions of apolipoprotein C alleles in native Asian sheep (Bengal, Kagi, Lampuchhre, Vietnamese, Myanmar, Baruwal, Bhyanglung, Khalkhas, and Kuwait) were determined using a one-dimensional polyacrylamide gel isoelectric-focusing immunoblotting technique. Among these Asian sheep, the genetic locus c...

journal_title：Biochemical genetics

authors： Tsunoda K,Watanabe S,Sato J,Sato K

更新日期：2002-12-01 00:00:00

abstract：:Experimental analysis of background dependent effects of genetic interactions can be designed using strains generated by introgression of small genetic regions containing identical genotypes at loci in question into different inbred strains. We use a novel multilocus paradigm, denoted conditional intergenic functional...

journal_title：Biochemical genetics

authors： Kovac I,Marinkovic D

更新日期：1999-02-01 00:00:00