The telomere-binding protein Taz1p as a target for modification by a SUMO-1 homologue in fission yeast.

abstract：:The murine polycystic kidney disease gene, pcy, is an autosomal recessive trait located on chromosome 9. To determine the genetic locus of pcy, 222 intraspecific backcross mice were obtained by mating C57BL/6FG-pcy and Mus molossinus. Restriction fragment length polymorphism analysis of 70 of the 222 backcross progeny...

journal_title：Biochemical genetics

authors： Nagao S,Watanabe T,Ogiso N,Marunouchi T,Takahashi H

更新日期：1995-12-01 00:00:00

abstract：:The goals of this study were to analyze the change in the global gene expression profile of exogenous human leukocyte antigen-G1 (HLA-G1) overexpressed in human embryonic stem (hES) cells and to explore the molecular mechanism by which the overexpression of HLA-G1 modifies immunologic pathways. Microarray and quantita...

journal_title：Biochemical genetics

authors： Zhu Y,Zhao S,Zhao H,Yao Y

更新日期：2012-10-01 00:00:00

abstract：:The nuclear factor of activated T lymphocytes (NFATc1) plays a critical role during valvular and septal development. Genetic variants may influence the biological function of the protein and thus play a role in susceptibility to valvuloseptal defects. Tandem repeat polymorphisms and a common nonsynonymous polymorphism...

journal_title：Biochemical genetics

authors： Gu H,Gong J,Qiu W,Cao H,Xu J,Chen S,Chen Y

更新日期：2011-10-01 00:00:00

abstract：:Polymorphic esterase and acetylcholinesterase alleles in the whitefly Bemisia tabaci were studied using electrophoretic and colorimetric assays. The segregation of these alleles between parental and F1 generations provided unequivocal evidence of haplodiploidy in this pest species. Unmated females, heterozygous at a p...

journal_title：Biochemical genetics

authors： Byrne FJ,Devonshire AL

更新日期：1996-04-01 00:00:00

abstract：:Phosphoglucomutase (PGM) of adult stage in Drosophilia melanogaster has been characterized by gel filtration, ion-exchange chromatography, and isoelectric focusing. The two common electrophoretic variants, PGMA and PGMB, differ with respect to their kinetic and stability parameters. PGMA is more thermostable than PGMB...

journal_title：Biochemical genetics

authors： Fucci L,Gaudio L,Rao R,Spanò A,Carfagna M

更新日期：1979-10-01 00:00:00

abstract：:Salvia miltiorrhiza is a well-known medicinal plant and functional food in Asia. The range of quality among its germplasms is irregular, which inevitably affects its health and economic benefits. We established a system comprising phenotypic characteristics, ISSR markers, and active constituents to facilitate the comp...

journal_title：Biochemical genetics

authors： Zhang Y,Li X,Wang Z

更新日期：2013-10-01 00:00:00

abstract：:Three new linkage groups of enzyme loci are described using Poeciliopsis monacha x P. viriosa-derived interspecific backcross hybrids. Comparison to known linkage groups of the confamilial genus Xiphophorus shows homology between Xiphophorus linkage group I and Poeciliopsis linkage group III, Xiphophorus linkage group...

journal_title：Biochemical genetics

authors： Morizot DC,Schultz RJ,Wells RS

更新日期：1990-02-01 00:00:00

abstract：:Nineteen inbred strains of the laboratory rat (Rattus norvegicus) were investigated for genetic differences by starch and agarose gel electrophoretic techniques. For six out of 21 loci, interstrain differences were observed: Tf, 6PGD, Es-1, Es-4, Es-5, and Svp. The variants are briefly described and the allelic distri...

journal_title：Biochemical genetics

authors： Bender K,Günther E

更新日期：1978-06-01 00:00:00

abstract：:Allelic frequencies at five polymorphic loci were determined in seven European and six Afrotropical populations of Drosophila melanogaster. African populations, which may be considered as ancestral for the species, showed a greater genetic diversity as measured by the number of alleles found. Within each geographic gr...

journal_title：Biochemical genetics

authors： David JR

更新日期：1982-08-01 00:00:00

abstract：:Eukaryotic translation initiation factors (eIFs) have been shown to be critical in the initiation of protein synthesis. Here, we report the cloning and characterization of a novel gene, LceIF1, from a potentially interesting forage grass, Leymus chinensis (Trin.). The expression results show that LceIF1 is expressed i...

journal_title：Biochemical genetics

authors： Sun YL,Hong SK

更新日期：2013-02-01 00:00:00

abstract：:The solubilized proteins of liver and brain from mice of two inbred strains (C57BL/6J and DBA/2J) and their hybrids were subfractionated by heparin Sepharose (H-S) CL-6B affinity chromatography. The H-S binding and nonbinding proteins were separated by two-dimensional electrophoresis. The protein patterns obtained wer...

journal_title：Biochemical genetics

authors： Jungblut P,Klose J

更新日期：1986-12-01 00:00:00

abstract：:Genetic variation of a codominantly inherited pancreas protease, designated CTRA-1, was discovered in the house mouse by isoelectric focusing in polyacrylamide gels. Phenotype CTRA-1A was found in MOLH/Fre and in the majority of common laboratory mouse strains. Phenotype CTRA-1B was found in PWD/Ph. It was characteriz...

journal_title：Biochemical genetics

authors： von Deimling OH,Gröning J,Gaa A

更新日期：1991-12-01 00:00:00

abstract：:Congenital heart disease is the most common congenital anomaly, representing an important cause of infant morbidity and mortality. Congenital heart disease represents a group of heart anomalies that include septal defects, valve defects, and outflow tract anomalies. The exact genetic, epigenetic, or environmental basi...

journal_title：Biochemical genetics

authors： Muntean I,Togănel R,Benedek T

更新日期：2017-04-01 00:00:00

abstract：:The Wood Stork (Mycteria americana) is a colonial wading bird of the tropical and lower subtropical zones. We assessed genetic structure within and among five stork colonies from the Brazilian Pantanal and compared our data with those from North American populations. Samples of 234 individuals were studied using prote...

journal_title：Biochemical genetics

authors： Del Lama SN,Lopes IF,Del Lama MA

更新日期：2002-04-01 00:00:00

abstract：:The aryl hydrocarbon hydroxylase (Ah) locus that controls the induction of chemical carcinogen-metabolizing enzymes in mice has been found to be linked to a new restriction-fragment length polymorphism (RFLP). Only C57BL/6 and closely related inbred strains displayed a 7.6-kb HindIII restriction fragment, while all ot...

journal_title：Biochemical genetics

authors： Cobb RR,Stoming TA,Whitney JB 3rd

更新日期：1987-06-01 00:00:00

abstract：:The primary structures of the alpha globins from CE/J, DBA/2J, and a stock of Potter's mice were determined to identify the amino acid substitutions associated with the unique isoelectric focusing patterns of these hemoglobins. In addition, the primary structures of the alpha globins from MOL III and PERU mice were st...

journal_title：Biochemical genetics

authors： Popp RA,Bailiff EG,Skow LC,Whitney JB 3rd

更新日期：1982-02-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) hypervariable segment I sequences (HVSI, 471 bp) of the control region and partial cytochrome b sequences (Cytb, 403 bp) were analyzed in three tentative species of the genus Mystacoleucus in China (M. chilopterus, M. marginatus, and M. lepturus). Not more than two mutations were found in bot...

journal_title：Biochemical genetics

authors： Kong QP,Yao YG,Huang SY,Huang JF,Zhang YP

更新日期：2003-10-01 00:00:00

abstract：:Human PQBP-1 is known to interact with triplet repeat disease gene products such as ataxin and huntingtin through their poly-glutamine (poly-Q) tracts. The poly-Q tracts show extensive variation in both the number and the configuration of repeats among species. A surface plasmon resonance assay showed clear interactio...

journal_title：Biochemical genetics

authors： Kurosaki T,Gojobori J,Ueda S

更新日期：2012-04-01 00:00:00

abstract：:Three distinct malathion carboxylesterase (MCE) phenotypes have been identified among strains of Lucilia cuprina. The high-activity phenotype shows 1.6- and 33-fold more MCE specific activity than the intermediate- and low-activity phenotypes, respectively. Flies with high MCE activity are 1000-fold more resistant to ...

journal_title：Biochemical genetics

authors： Smyth KA,Russell RJ,Oakeshott JG

更新日期：1994-12-01 00:00:00

abstract：:Nucleophosmin/nucleoplasmin has been studied mostly in mammals and amphibians. To clarify the characteristics and function of nucleophosmin/nucleoplasmin in teleost fish, we cloned a full-length cDNA sequence from two cyprinid fish, Carassius auratus gibelio and Carassius auratus. Molecular characterization and multip...

journal_title：Biochemical genetics

authors： Wu N,Li CJ,Gui JF

更新日期：2009-12-01 00:00:00

abstract：:Site-specific gene modifications in cells are initiated by the introduction of exogenous DNA. We used a recently established cell assay to compare the ability of DNA donors to induce a single point mutation that converts a target gene encoding blue fluorescent protein (BFP) into expressing green fluorescent protein (G...

journal_title：Biochemical genetics

authors： Wagner S,McCracken J,Cole S,Laible G

更新日期：2010-12-01 00:00:00

abstract：:Pancreatic cancer is the fourth leading cause of death in both males and females, with a 5-year relative survival rate of 8%. The Wnt signaling pathway has a significant role in the pathogenesis of many tumors, including those of pancreatic cancer. Hypermethylation of the Wnt inhibitory Factor-1 (WIF1) gene promoter h...

journal_title：Biochemical genetics

authors： Rahmani B,Hamedi Asl D,Naserpour Farivar T,Azad M,Sahmani M,Gheibi N

更新日期：2019-08-01 00:00:00

abstract：:Neurospora crassa can utilize numerous compounds including certain amino acids as a sole nitrogen source. Mutants of the nit-2 locus, a regulatory gene which is postulated to mediate nitrogen catabolite repression, are deficient in the ability to utilize several amino acids as well as other nitrogen sources used by wi...

journal_title：Biochemical genetics

authors： Facklam TJ,Marzluf GA

更新日期：1978-04-01 00:00:00

abstract：:Two complementing loci in different linkage groups of the basidiomycete Ustilago violacea are involved in urease activity: a structural one (ure-1) and a second inferred to involve a permease (ure-2) locus. Two types of complementing mutations occur in the structural locus: null activity (ure-la) and obviously reduced...

journal_title：Biochemical genetics

authors： Baird ML,Garber ED

更新日期：1981-12-01 00:00:00

abstract：:The locus for sorbitol dehydrogenase (SORD, E.C. 1.1.1.14) has been shown to segregate with hexosaminidase A and mannose phosphate isomerase in a series of human-Chinese hamster somatic cell hybrids. Cytogenetic analysis supports the assignment to chromosome 15 and further defines the gene locus to the region 15pter l...

journal_title：Biochemical genetics

authors： Donald LJ,Wang HS,Hamerton JL

更新日期：1980-06-01 00:00:00

abstract：:In Neurospora crassa, the expression of unlinked structural genes which encode nitrogen catabolic enzymes is subject to genetic and metabolic regulation. The negative-acting nmr regulatory gene appears to play a role in nitrogen catabolite repression. Using the N. crassa nmr gene as a probe, homologous sequences were ...

journal_title：Biochemical genetics

authors： Young JL,Marzluf GA

更新日期：1991-10-01 00:00:00

abstract：:Polysomes from 5.5-day and 6.5-day embryonic chick erythroid cells contain messenger RNA (mRNA) which can be translated into products in a cell-free protein-synthesizing system. The products of the cell-free system coelectrophoresed with carrier globin chains from the cells from which the polysomal pellet was isolated...

journal_title：Biochemical genetics

authors： Zagris N

更新日期：1977-10-01 00:00:00

abstract：:Experiments utilizing standard techniques of cell fractionation and disc electrophoresis have revealed the presence of three distinctly different enzymes which catalyze the oxidation of D-sorbitol in crude extracts of Drosophila melanogaster adults. These include (1) a soluble NAD-dependent sorbitol dehydrogenase (NAD...

journal_title：Biochemical genetics

authors： Bischoff WL

更新日期：1976-12-01 00:00:00

abstract：:In vitro DNA:DNA hybridizations and hydroxyapatite thermal-elution chromatography were employed to identify the diploid Triticum species ancestral to the B genome of T. turgidum. Unique and repeated sequences from the various Triticum species were separated by hybridization and thermal elution on hydroxyapatite. Uniqu...

journal_title：Biochemical genetics

authors： Thompson JP,Nath J

更新日期：1986-02-01 00:00:00

abstract：:For a number of decades, the lesser white-fronted goose (Anser erythropus) has been almost-absent from the Fennoscandian fauna and has a current population size of only about 60 breeding pairs, with fewer than 10 pairs in Sweden. During the period 1981-1991 more than 200 young have been reintroduced in northern Sweden...

journal_title：Biochemical genetics

authors： Tegelström H,von Essen L

更新日期：1996-08-01 00:00:00